Research Topics
| B R BrooksSummaryAffiliation: University of Wisconsin Country: USA Publications
| Collaborators
|
Detail Information
Publications
Risk factors in the early diagnosis of ALS: North American epidemiological studies. ALS CARE Study GroupB R Brooks
University of Wisconsin Hospital and Clinics, ALS Clinical Research Center, Madison 53792 5132, USA
Amyotroph Lateral Scler Other Motor Neuron Disord 1:S19-26. 2000..No significant difference was found in the median time to diagnose sporadic ALS patients compared with familial ALS patients...- Versailles minimal dataset for diagnosis of ALS: a distillate of the 2nd Consensus Conference on accelerating the diagnosis of ALS. Versailles 2nd Consensus Conference participantsB R Brooks
University of Wisconsin Hospital and Clinics, ALS Clinical Research Center, Madison 53792 5132, USA
Amyotroph Lateral Scler Other Motor Neuron Disord 1:S79-81. 2000.... - Functional magnetic resonance imaging (fMRI) clinical studies in ALS--paradigms, problems and promisesB R Brooks
Neurology Department, University of Wisconsin Madison Medical School, 53792 5132, USA
Amyotroph Lateral Scler Other Motor Neuron Disord 1:S23-32. 2000..fMRI studies will complement other clinical neurophysiological and neuroimaging techniques in our future attempts to solve the riddle of ALS and other motor neuron diseases... - Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trialB R Brooks
University of Wisconsin, 600 Highland Ave, Rm H6 563 CSC, Madison, WI 53792 5132, USA
Neurology 63:1364-70. 2004..Patients with ALS commonly exhibit pseudobulbar affect... - Problems in shortening the time to confirmation of ALS diagnosis: lessons from the 1st Consensus Conference, Chicago, May 1998B R Brooks
University of Wisconsin Hospital and Clinics, ALS Clinical Research Center, Madison 53792 5132, USA
Amyotroph Lateral Scler Other Motor Neuron Disord 1:S3-7. 2000..Refining this ALS knowledge-base is required to identify a minimum dataset required for the evaluation and diagnosis of ALS... - Earlier is better: the benefits of early diagnosisB R Brooks
ALS Clinical Research Center, University of Wisconsin Madison, and William S Middleton Memorial VA Medical Center, 53792 5132, USA
Neurology 53:S53-4; discussion S55-7. 1999..Finally, earlier diagnosis of ALS requires decisions to be made concerning the acceptable rate of misdiagnosis, which at present reaches 10% false-positive and up to 44% false-negative... - What are the implications of early diagnosis? Maintaining optimal health as long as possibleB R Brooks
ALS Clinical Research Center, University of Wisconsin Madison and William S Middleton Memorial VA Medical Center, 53792 5132, USA
Neurology 53:S43-5; discussion S55-7. 1999..The development of a staging system, analogous to the ones used in oncology, has implications for the concept of early diagnosis... - Defining optimal management in ALS: from first symptoms to announcementB R Brooks
ALS Clinical Research Center, University of Wisconsin Madison, and William S Middleton Memorial VA Medical Center, 53792 5132, USA
Neurology 53:S1-3; discussion S20-1. 1999..The goals were to examine current diagnosis and treatment pathways and to attempt to devise an algorithm that would foster early diagnosis, thus enhancing the possibility of optimal treatment... - Diagnostic dilemmas in amyotrophic lateral sclerosisB R Brooks
ALS Clinical Research Center, University of Wisconsin Hospital and Clinics, Clinical Science Center, Madison 53972 5132, USA
J Neurol Sci 165:S1-9. 1999..Neuroimaging and electromyography were important in shortening the time in which patients were given a diagnosis of clinically definite ALS. Other diagnostic dilemmas in ALS and the role of early diagnosis of this disease are discussed... - Quantitative assessment of motor fatigue in amyotrophic lateral sclerosisM Sanjak
ALS Clinical Research Center, University of Wisconsin Madison Medical School, Madison, WI 53792 5132, USA
J Neurol Sci 191:55-9. 2001..15%) in all muscles including muscles that were not clearly weak. Weakness and fatigue were poorly correlated in ALS patients and may be independent measures of the pathogeneses of ALS... - Zidovudine [AZT] myotoxicity: quantitative separation of AZT effects on proliferation and differentiation of muscle cells in vitro. Lack of myotoxicity potentiation by retrovirusA J Waclawik
Neurology Department, University of Wisconsin Medical School, William S Middleton Memorial Veterans Affairs Hospital, Madison 53792, USA
Neurotoxicology 20:49-56. 1999..These results suggest that AZT may impair muscle fiber regeneration in the course of retrovirus associated myopathy. The mechanism of AZT myotoxicity was not explained by alterations in total mitochondrial DNA content... - Dissociation between mechanical and myoelectrical manifestation of muscle fatigue in amyotrophic lateral sclerosisM Sanjak
Department of Neurology, H 6 577 ALS Clinical Research Center, Medical School, University of Wisconsin Madison, 600 Highland Avenue, Madison, WI 53799, USA
Amyotroph Lateral Scler Other Motor Neuron Disord 5:26-32. 2004..Alterations in motor unit functionality, especially in type II fast motor unit muscle fibers, and structural damage in denervated muscle fibers may contribute to the lower MFCV during motor fatigue in ALS patients... - Multiple tactile maps in the human cerebellumK O Bushara
Department of Neurology, University of Wisconsin, Minneapolis Veterans Affairs Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA
Neuroreport 12:2483-6. 2001..in agreement with previous functional imaging studies, our results show a large-scale, between-limb somatotopy comparable to that shown in early animal studies... - Failure to detect enterovirus in the spinal cord of ALS patients using a sensitive RT-PCR methodW A Nix
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Neurology 62:1372-7. 2004..CONCLUSION: The reported association between EV infection and ALS was not confirmed by testing this set of specimens with these sensitive methods... - Subcortical reorganization in amyotrophic lateral sclerosisC Konrad
Department of Psychiatry and Psychotherapy, IZKF, University of Muenster, Albert Schweitzer Str 11, 48149 Muenster, Germany
Exp Brain Res 172:361-9. 2006....