Natasja Brooijmans

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Molecular recognition and docking algorithms
    Natasja Brooijmans
    Chemistry and Chemical Biology Graduate Program University of California San Francisco, San Francisco, California 94143 2240, USA
    Annu Rev Biophys Biomol Struct 32:335-73. 2003
  2. ncbi request reprint Development and validation of a modular, extensible docking program: DOCK 5
    Demetri T Moustakas
    Joint Graduate Program in Bioengineering, University of California, San Francisco, 600 16th Street, Genentech Hall, Box 2240, San Francisco, CA 94143, USA
    J Comput Aided Mol Des 20:601-19. 2006
  3. ncbi request reprint Stability of macromolecular complexes
    Natasja Brooijmans
    Graduate Program in Chemistry and Chemical Biology, University of California San Francisco, San Francisco, California 94143 0446, USA
    Proteins 48:645-53. 2002

Collaborators

  • Kim Sharp
  • Demetri T Moustakas
  • Irwin D Kuntz
  • SCOTT PEGG
  • Eric Pettersen
  • Robert C Rizzo
  • P Therese Lang

Detail Information

Publications3

  1. ncbi request reprint Molecular recognition and docking algorithms
    Natasja Brooijmans
    Chemistry and Chemical Biology Graduate Program University of California San Francisco, San Francisco, California 94143 2240, USA
    Annu Rev Biophys Biomol Struct 32:335-73. 2003
    ..More recent applications of computational chemistry tools involve library design and database screening. Last, we summarize several critical methodological issues that must be addressed in future developments...
  2. ncbi request reprint Development and validation of a modular, extensible docking program: DOCK 5
    Demetri T Moustakas
    Joint Graduate Program in Bioengineering, University of California, San Francisco, 600 16th Street, Genentech Hall, Box 2240, San Francisco, CA 94143, USA
    J Comput Aided Mol Des 20:601-19. 2006
    ..We point out that success rates could be improved through more advanced modeling of the receptor prior to docking and through improvement of the force field parameters, particularly for structures containing metal-based cofactors...
  3. ncbi request reprint Stability of macromolecular complexes
    Natasja Brooijmans
    Graduate Program in Chemistry and Chemical Biology, University of California San Francisco, San Francisco, California 94143 0446, USA
    Proteins 48:645-53. 2002
    ..These results are consistent with the widespread observation that proteins have not evolved to maximize thermodynamic stability, but are only marginally stable...