J M Bronstein

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Disrupted compaction of CNS myelin in an OSP/Claudin-11 and PLP/DM20 double knockout mouse
    E Chow
    Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095, USA
    Mol Cell Neurosci 29:405-13. 2005
  2. doi request reprint Deep brain stimulation for Parkinson disease: an expert consensus and review of key issues
    Jeff M Bronstein
    University of California, Los Angeles, School of Medicine, Department of Neurology, 710 Westwood Plaza, Los Angeles, CA 90095, USA
    Arch Neurol 68:165. 2011
  3. ncbi request reprint Function of tetraspan proteins in the myelin sheath
    J M Bronstein
    UCLA School of Medicine, Department of Neurology, Reed Neurological Research Center, 710 Westwood Plaza, Los Angeles, CA 90095, USA
    Curr Opin Neurobiol 10:552-7. 2000
  4. ncbi request reprint Involvement of OSP/claudin-11 in oligodendrocyte membrane interactions: role in biology and disease
    J M Bronstein
    Departments of Neurology and the Brain Research Institute, UCLA School of Medicine, Los Angeles, CA 90095, USA
    J Neurosci Res 59:706-11. 2000
  5. ncbi request reprint Stereotactic pallidotomy in the treatment of Parkinson disease: an expert opinion
    J M Bronstein
    Department of Neurology, University of California, Los Angeles, School of Medicine, 90024, USA
    Arch Neurol 56:1064-9. 1999
  6. ncbi request reprint A humoral response to oligodendrocyte-specific protein in MS: a potential molecular mimic
    J M Bronstein
    Department of Neurology and the Brain Research Institute, UCLA School of Medicine, Los Angeles, CA 90024, USA
    Neurology 53:154-61. 1999
  7. ncbi request reprint Oligodendrocyte-specific protein (OSP) is a major component of CNS myelin
    J M Bronstein
    Department of Neurology, University of California, Los Angeles School of Medicine, 90024, USA
    J Neurosci Res 50:713-20. 1997
  8. pmc OSP/claudin-11 forms a complex with a novel member of the tetraspanin super family and beta1 integrin and regulates proliferation and migration of oligodendrocytes
    S K Tiwari-Woodruff
    Department of Neurology, University of California at Los Angeles School of Medicine, Los Angeles, California 90095, USA
    J Cell Biol 153:295-305. 2001
  9. ncbi request reprint Developmental expression of OSP/claudin-11
    J M Bronstein
    Department of Neurology, UCLA School of Medicine, Los Angeles, California 90024, USA
    J Neurosci Res 60:284-90. 2000
  10. ncbi request reprint Cerebrospinal fluid immunoglobulin G promotes oligodendrocyte progenitor cell migration
    S K Tiwari-Woodruff
    Department of Neurology and the Brain Research Institute, UCLA School of Medicine, Los Angeles, California 90095, USA
    J Neurosci Res 77:363-6. 2004

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Disrupted compaction of CNS myelin in an OSP/Claudin-11 and PLP/DM20 double knockout mouse
    E Chow
    Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095, USA
    Mol Cell Neurosci 29:405-13. 2005
    ..These data demonstrate that OSP/claudin-11 and PLP have essential structural functions in maintaining normal compact myelin and there is redundancy in their functions...
  2. doi request reprint Deep brain stimulation for Parkinson disease: an expert consensus and review of key issues
    Jeff M Bronstein
    University of California, Los Angeles, School of Medicine, Department of Neurology, 710 Westwood Plaza, Los Angeles, CA 90095, USA
    Arch Neurol 68:165. 2011
    ..To provide recommendations to patients, physicians, and other health care providers on several issues involving deep brain stimulation (DBS) for Parkinson disease (PD)...
  3. ncbi request reprint Function of tetraspan proteins in the myelin sheath
    J M Bronstein
    UCLA School of Medicine, Department of Neurology, Reed Neurological Research Center, 710 Westwood Plaza, Los Angeles, CA 90095, USA
    Curr Opin Neurobiol 10:552-7. 2000
    ..In addition, several new myelin tetraspans have been identified that are involved in adhesion, molecular trafficking, growth regulation, and migration of oligodendrocytes and Schwann cells...
  4. ncbi request reprint Involvement of OSP/claudin-11 in oligodendrocyte membrane interactions: role in biology and disease
    J M Bronstein
    Departments of Neurology and the Brain Research Institute, UCLA School of Medicine, Los Angeles, CA 90095, USA
    J Neurosci Res 59:706-11. 2000
    ..Furthermore, evidence is presented implicating OSP/claudin-11 as an autoantigen in the development of autoimmune demyelinating disease...
  5. ncbi request reprint Stereotactic pallidotomy in the treatment of Parkinson disease: an expert opinion
    J M Bronstein
    Department of Neurology, University of California, Los Angeles, School of Medicine, 90024, USA
    Arch Neurol 56:1064-9. 1999
    ..Benefits of pallidotomy appear to be long lasting. (5) Each institution's complication rate should be discussed before surgery...
  6. ncbi request reprint A humoral response to oligodendrocyte-specific protein in MS: a potential molecular mimic
    J M Bronstein
    Department of Neurology and the Brain Research Institute, UCLA School of Medicine, Los Angeles, CA 90024, USA
    Neurology 53:154-61. 1999
    ..To determine the antibody response to oligodendrocyte-specific protein (OSP) in patients with MS...
  7. ncbi request reprint Oligodendrocyte-specific protein (OSP) is a major component of CNS myelin
    J M Bronstein
    Department of Neurology, University of California, Los Angeles School of Medicine, 90024, USA
    J Neurosci Res 50:713-20. 1997
    ..No binding was found to several agglutinins or a HNK1-specific antibody suggesting that OSP is not a glycoprotein...
  8. pmc OSP/claudin-11 forms a complex with a novel member of the tetraspanin super family and beta1 integrin and regulates proliferation and migration of oligodendrocytes
    S K Tiwari-Woodruff
    Department of Neurology, University of California at Los Angeles School of Medicine, Los Angeles, California 90095, USA
    J Cell Biol 153:295-305. 2001
    ..These data suggest a role for OSP/claudin-11, OAP-1, and beta1 integrin complex in regulating proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair...
  9. ncbi request reprint Developmental expression of OSP/claudin-11
    J M Bronstein
    Department of Neurology, UCLA School of Medicine, Los Angeles, California 90024, USA
    J Neurosci Res 60:284-90. 2000
    ..These data demonstrate that OSP/claudin-11 expression is highly regulated during development and, therefore, may play an important role in growth and differentiation of oligodendrocytes and other cells outside the CNS...
  10. ncbi request reprint Cerebrospinal fluid immunoglobulin G promotes oligodendrocyte progenitor cell migration
    S K Tiwari-Woodruff
    Department of Neurology and the Brain Research Institute, UCLA School of Medicine, Los Angeles, California 90095, USA
    J Neurosci Res 77:363-6. 2004
    ..These data demonstrate that CSF IgG promotes OPC migration. Identification of the specific IgG fraction responsible for this effect could lead to novel therapies to promote recovery in MS...
  11. ncbi request reprint Motor, cognitive, and behavioral performance following unilateral ventroposterior pallidotomy for Parkinson disease
    D Masterman
    Department of Neurology, University of California, Los Angeles School of Medicine, USA
    Arch Neurol 55:1201-8. 1998
    ..To evaluate the effects of ventroposterior pallidotomy on motor disability and on behavior and cognition in patients with medically intractable idiopathic Parkinson disease...
  12. ncbi request reprint Staged bilateral pallidotomy for treatment of Parkinson disease
    P M Intemann
    Department of Neurology, University of California at Los Angeles School of Medicine, 90024, USA
    J Neurosurg 94:437-44. 2001
    ..CONCLUSIONS: Bilateral pallidotomy results in modest benefits but is associated with an increased risk of complications...
  13. ncbi request reprint T-cell responses to oligodendrocyte-specific protein in multiple sclerosis
    T Vu
    Department of Neurology and the Brain Research Institute, UCLA School of Medicine, Los Angeles, California 90095, USA
    J Neurosci Res 66:506-9. 2001
    ..Given the lack of specificity to MS, OSP-reactive T-cells are unlikely to be solely responsible for the disease process...
  14. ncbi request reprint Isolation and characterization of a novel oligodendrocyte-specific protein
    J M Bronstein
    UCLA School of Medicine, Department of Neurology 90024, USA
    Neurology 47:772-8. 1996
    ..Since OSP is localized to oligodendrocytes and myelin, has a similar structure with PMP-22, and has a developmental pattern of expression like other myelin proteins, it probably has an important role in CNS myelinogenesis...
  15. ncbi request reprint Treatment of a patient by vaccination with autologous dendritic cells pulsed with allogeneic major histocompatibility complex class I-matched tumor peptides. Case Report
    L M Liau
    Division of Neurosurgery, Department of Neurology, University of California at Los Angeles School of Medicine, Los Angeles, California 90095 6901, USA
    Neurosurg Focus 9:e8. 2000
    ..Phase I trials for malignant glioma are currently underway...
  16. ncbi request reprint Identification of a human glioma-associated growth factor gene, granulin, using differential immuno-absorption
    L M Liau
    Division of Neurosurgery, Jonsson Comprehensive Cancer Center, University of California at Los Angeles School of Medicine, 90095 6901, USA
    Cancer Res 60:1353-60. 2000
    ....
  17. ncbi request reprint Treatment of intracranial gliomas with bone marrow-derived dendritic cells pulsed with tumor antigens
    L M Liau
    Department of Neurology, Jonsson Comprehensive Cancer Center, University of California at Los Angeles School of Medicine, 90095, USA
    J Neurosurg 90:1115-24. 1999
    ..The authors investigated the ability of "professional" antigen-presenting cells (dendritic cells) to enhance host antitumor immune responses when injected as a vaccine into tumor-bearing animals...
  18. ncbi request reprint Prenatal ontogeny of the epidermal growth factor receptor and its ligand, transforming growth factor alpha, in the rat brain
    H I Kornblum
    Department of Molecular and Medical Pharmacology, UCLA School of Medicine 90095, USA
    J Comp Neurol 380:243-61. 1997
    ..These data indicate that TGF alpha and EGF-R are positioned to have a role in the genesis, differentiation, migration, or survival of numerous cell populations in the embryonic brain...
  19. ncbi request reprint TRPM-2 expression and tunel staining in neurodegenerative diseases: studies in wobbler and rd mice
    P Popper
    Department of Neurobiology, University of California, Los Angeles, California, 90095, USA
    Exp Neurol 143:246-54. 1997
    ..In the wobbler spinal cords dying motoneurons were not labeled. These data suggest that the process of neurodegenerative motoneuron cell death in wobbler mice is different from the apoptotic process of rd photoreceptors...
  20. ncbi request reprint Deep brain stimulation in intraoperative MRI environment - comparison of imaging techniques and electrode fixation methods
    M W Y Lee
    Division of Neurosurgery, University of California Los Angeles School of Medicine, Los Angeles, USA
    Minim Invasive Neurosurg 48:1-6. 2005
    ..Satisfactory microelectrode recording was feasible in low-field 0.2 T and high-field 1.5 T MRI environments. Further studies on performing DBS in real-time intraoperative MRI are warranted...
  21. ncbi request reprint Chromosomal localization of murine and human oligodendrocyte-specific protein genes
    J M Bronstein
    Department of Neurology, UCLA School of Medicine, Los Angeles, California, 90024, USA
    Genomics 34:255-7. 1996
    ..Fine mapping with fluorescence in situ hybridization placed the OSP gene at human chromosome 3q26.2-q26.3. To date, there are no known inherited neurological disorders that localize to these regions...
  22. ncbi request reprint CNS myelin and sertoli cell tight junction strands are absent in Osp/claudin-11 null mice
    A Gow
    Brookdale Center for Developmental and Molecular Biology, Mount Sinai School of Medicine, New York, New York 10029, USA
    Cell 99:649-59. 1999
    ..These novel results provide direct evidence of the pivotal role of the claudin family in generating the paracellular physical barrier of tight junctions necessary for spermatogenesis and normal CNS function...