Affiliation: University of Wisconsin
- Mapping quantitative trait loci onto a phylogenetic treeKarl W Broman
Department of Biostatistics and Medical Informatics, Genetics, University of Wisconsin, Madison, Wisconsin 53706, USA
Genetics 192:267-79. 2012..Finally, we explore the method's performance in computer simulations, and we illustrate its use through application to a set of four mouse intercrosses among five inbred strains, with data on HDL cholesterol...
- Genotype probabilities at intermediate generations in the construction of recombinant inbred linesKarl W Broman
Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, Wisconsin 53706, USA
Genetics 190:403-12. 2012..In addition, I present a number of useful quantities, including single-locus genotype probabilities, two-locus haplotype probabilities, and the fixation probability and map expansion at each generation along the course to inbreeding...
- Detecting single-nucleotide polymorphism by single-nucleotide polymorphism interactions in rheumatoid arthritis using a two-step approach with machine learning and a Bayesian threshold least absolute shrinkage and selection operator (LASSO) modelOscar González-Recio
Department of Dairy Science, University of Wisconsin Madison, 266 Animal Science Building, 1675 Observatory Drive, Madison, Wisconsin 53706, USA
BMC Proc 3:S63. 2009..g., rs2395175, rs660895, rs10484560, and rs2476601). Further, some other SNPs detected in this study may be considered in candidate gene studies...
- Differential MHC class I expression in distinct leukocyte subsetsJustin M Greene
Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, 53706 Wisconsin, USA
BMC Immunol 12:39. 2011..It is unclear how cDNA species are expressed in distinct cell subsets in humans and particularly in macaques which transcribe upwards of 20 distinct MHC class I alleles at variable levels...
- Characterization of killer immunoglobulin-like receptor genetics and comprehensive genotyping by pyrosequencing in rhesus macaquesAnna J Moreland
Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
BMC Genomics 12:295. 2011..Rhesus macaques serve as important animal models for many human diseases in which KIRs are implicated; however, the study of KIR activity in this model is hindered by incomplete characterization of KIR genetics...