FRANCES BRODSKY

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step
    Christopher Esk
    Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA
    J Cell Biol 188:131-44. 2010
  2. pmc Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG
    Amy B Foraker
    Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 94143, USA
    J Cell Biol 198:591-605. 2012
  3. pmc The CHC22 clathrin-GLUT4 transport pathway contributes to skeletal muscle regeneration
    Sachiko Hoshino
    The G W Hooper Foundation, Departments of Bioengineering and Therapeutic Sciences, Pharmaceutical Chemistry, and Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America Department of Neurology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    PLoS ONE 8:e77787. 2013
  4. doi request reprint Diversity of clathrin function: new tricks for an old protein
    Frances M Brodsky
    Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California 94143 0552, USA
    Annu Rev Cell Dev Biol 28:309-36. 2012
  5. doi request reprint Evolutionary cell biology: Lessons from diversity
    Frances M Brodsky
    University of California, San Francisco, California 94143, USA
    Nat Cell Biol 14:651. 2012
  6. pmc Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
    Dun Yang
    G W Hooper Foundation and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143 0552, USA
    Proc Natl Acad Sci U S A 99:9942-7. 2002
  7. pmc Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain
    Jeremy D Wilbur
    Graduate Program in Biophysics, University of California, San Francisco, California 94143, USA
    Acta Crystallogr D Biol Crystallogr 66:314-8. 2010

Research Grants

  1. STRUCTURAL BASIS FOR CLATHRIN FUNCTION
    FRANCES BRODSKY; Fiscal Year: 2002

Collaborators

Detail Information

Publications7

  1. pmc The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step
    Christopher Esk
    Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA
    J Cell Biol 188:131-44. 2010
    ..Like CHC22, syntaxin 10 is not expressed in mice but is present in humans and other vertebrates, implicating two species-restricted endosomal traffic proteins in GLUT4 transport...
  2. pmc Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG
    Amy B Foraker
    Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 94143, USA
    J Cell Biol 198:591-605. 2012
    ..Therefore, we propose that clathrin promotes centrosome maturation by stabilizing the microtubule-binding protein ch-TOG, defining a novel role for the clathrin-ch-TOG-TACC3 complex...
  3. pmc The CHC22 clathrin-GLUT4 transport pathway contributes to skeletal muscle regeneration
    Sachiko Hoshino
    The G W Hooper Foundation, Departments of Bioengineering and Therapeutic Sciences, Pharmaceutical Chemistry, and Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America Department of Neurology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    PLoS ONE 8:e77787. 2013
    ..Extrapolating these findings, CHC22 and GLUT4 can be considered markers of muscle regeneration in humans. ..
  4. doi request reprint Diversity of clathrin function: new tricks for an old protein
    Frances M Brodsky
    Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California 94143 0552, USA
    Annu Rev Cell Dev Biol 28:309-36. 2012
    ..By considering these diverse clathrin functions, along with intracellular sorting roles and influences on mitosis, further relevance of clathrin function to human health and disease is established...
  5. doi request reprint Evolutionary cell biology: Lessons from diversity
    Frances M Brodsky
    University of California, San Francisco, California 94143, USA
    Nat Cell Biol 14:651. 2012
    ..Novel perspectives emerge from a recent conference on the origins of eukaryotic cells, which covered phylogenetics, population genetics and evolutionary consequences of energy requirements and host–pathogen interactions...
  6. pmc Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
    Dun Yang
    G W Hooper Foundation and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143 0552, USA
    Proc Natl Acad Sci U S A 99:9942-7. 2002
    ..esiRNA works by eliciting the destruction of its cognate mRNA. Because of its simplicity and potency, this approach is useful for analysis of mammalian gene functions...
  7. pmc Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain
    Jeremy D Wilbur
    Graduate Program in Biophysics, University of California, San Francisco, California 94143, USA
    Acta Crystallogr D Biol Crystallogr 66:314-8. 2010
    ..A hydrogen-bond network and changes in coiled-coil monomer interaction suggest that the HIP1 coiled-coil domain is uniquely suited to allow conformational flexibility...

Research Grants1

  1. STRUCTURAL BASIS FOR CLATHRIN FUNCTION
    FRANCES BRODSKY; Fiscal Year: 2002
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