FRANCES BRODSKY

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Diversity of clathrin function: new tricks for an old protein
    Frances M Brodsky
    Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California 94143 0552, USA
    Annu Rev Cell Dev Biol 28:309-36. 2012
  2. doi request reprint Evolutionary cell biology: Lessons from diversity
    Frances M Brodsky
    University of California, San Francisco, California 94143, USA
    Nat Cell Biol 14:651. 2012
  3. pmc Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
    Dun Yang
    G W Hooper Foundation and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143 0552, USA
    Proc Natl Acad Sci U S A 99:9942-7. 2002
  4. pmc Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain
    Jeremy D Wilbur
    Graduate Program in Biophysics, University of California, San Francisco, California 94143, USA
    Acta Crystallogr D Biol Crystallogr 66:314-8. 2010

Research Grants

  1. STRUCTURAL BASIS FOR CLATHRIN FUNCTION
    FRANCES BRODSKY; Fiscal Year: 2002
  2. CELLULAR REGULATION OF CLATHRIN ASSEMBLY AND FUNCTION
    FRANCES BRODSKY; Fiscal Year: 2006
  3. CELLULAR REGULATION OF CLATHRIN ASSEMBLY AND FUNCTION
    FRANCES BRODSKY; Fiscal Year: 2007
  4. CELLULAR REGULATION OF CLATHRIN ASSEMBLY AND FUNCTION
    FRANCES BRODSKY; Fiscal Year: 2007
  5. CELLULAR REGULATION OF CLATHRIN ASSEMBLY AND FUNCTION
    FRANCES BRODSKY; Fiscal Year: 2002
  6. MOLECULAR MECHANISM OF CLATHRIN ASSEMBLY
    FRANCES BRODSKY; Fiscal Year: 1990
  7. THE MOLECULAR MECHANISM OF CLATHRIN ASSEMBLY
    FRANCES BRODSKY; Fiscal Year: 1993
  8. CELLULAR REGULATION OF CLATHRIN ASSEMBLY AND FUNCTION
    Frances M Brodsky; Fiscal Year: 2010

Detail Information

Publications4

  1. doi request reprint Diversity of clathrin function: new tricks for an old protein
    Frances M Brodsky
    Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California 94143 0552, USA
    Annu Rev Cell Dev Biol 28:309-36. 2012
    ..By considering these diverse clathrin functions, along with intracellular sorting roles and influences on mitosis, further relevance of clathrin function to human health and disease is established...
  2. doi request reprint Evolutionary cell biology: Lessons from diversity
    Frances M Brodsky
    University of California, San Francisco, California 94143, USA
    Nat Cell Biol 14:651. 2012
    ..Novel perspectives emerge from a recent conference on the origins of eukaryotic cells, which covered phylogenetics, population genetics and evolutionary consequences of energy requirements and host–pathogen interactions...
  3. pmc Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
    Dun Yang
    G W Hooper Foundation and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143 0552, USA
    Proc Natl Acad Sci U S A 99:9942-7. 2002
    ..esiRNA works by eliciting the destruction of its cognate mRNA. Because of its simplicity and potency, this approach is useful for analysis of mammalian gene functions...
  4. pmc Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain
    Jeremy D Wilbur
    Graduate Program in Biophysics, University of California, San Francisco, California 94143, USA
    Acta Crystallogr D Biol Crystallogr 66:314-8. 2010
    ..A hydrogen-bond network and changes in coiled-coil monomer interaction suggest that the HIP1 coiled-coil domain is uniquely suited to allow conformational flexibility...

Research Grants31

  1. STRUCTURAL BASIS FOR CLATHRIN FUNCTION
    FRANCES BRODSKY; Fiscal Year: 2002
    ..abstract_text> ..
  2. CELLULAR REGULATION OF CLATHRIN ASSEMBLY AND FUNCTION
    FRANCES BRODSKY; Fiscal Year: 2006
    ..We anticipate that these latter studies will initiate new approaches to investigation of human disease states in which clathrin function is involved. ..
  3. CELLULAR REGULATION OF CLATHRIN ASSEMBLY AND FUNCTION
    FRANCES BRODSKY; Fiscal Year: 2007
    ..Understanding clathrin function therefore has relevance for establishing molecular mechanisms of a number of human disease states such as heart disease, diabetes, cancer, neuro-muscular defects and infection and immunity. ..
  4. CELLULAR REGULATION OF CLATHRIN ASSEMBLY AND FUNCTION
    FRANCES BRODSKY; Fiscal Year: 2007
    ..abstract_text> ..
  5. CELLULAR REGULATION OF CLATHRIN ASSEMBLY AND FUNCTION
    FRANCES BRODSKY; Fiscal Year: 2002
    ..Genetic deletion will be used to define LCa and LCb function in mice, providing the first insight into tissue-specific and systemic roles of CCV-mediated membrane traffic. ..
  6. MOLECULAR MECHANISM OF CLATHRIN ASSEMBLY
    FRANCES BRODSKY; Fiscal Year: 1990
    ....
  7. THE MOLECULAR MECHANISM OF CLATHRIN ASSEMBLY
    FRANCES BRODSKY; Fiscal Year: 1993
    ..This will ultimately contribute to design of receptor-mediated therapeutics and to new approaches to vaccination, since this pathway is utilized for the uptake and processing of foreign antigens...
  8. CELLULAR REGULATION OF CLATHRIN ASSEMBLY AND FUNCTION
    Frances M Brodsky; Fiscal Year: 2010
    ..Understanding clathrin function therefore has relevance for establishing molecular mechanisms of a number of human disease states such as heart disease, diabetes, cancer, neuro-muscular defects and infection and immunity. ..