Research Topics
| Eliot A BrintonSummaryAffiliation: University of Utah Country: USA Publications
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Detail Information
Publications
Does the addition of fibrates to statin therapy have a favorable risk to benefit ratio?Eliot A Brinton
Cardiovascular Genetics, University of Utah School of Medicine, 420 Chipeta Way, Room 1160, Salt Lake City, UT 84108, USA
Curr Atheroscler Rep 10:25-32. 2008..This review provides an update on the benefits and risks of fibrate monotherapy and addresses the benefits and risks of adding fibrates to statins...
Niacin extended-release therapy in phase III clinical trials is associated with relatively low rates of drug discontinuation due to flushing and treatment-related adverse events: a pooled analysisEliot A Brinton
Cardiovascular Genetics, University of Utah School of Medicine, Salt Lake City, UT 84108, USA
Am J Cardiovasc Drugs 11:179-87. 2011..In this study, we pooled safety data from available trials of at least 16 weeks' duration to evaluate the impact of flushing on patient adherence to niacin extended-release (NER) therapy...
Effects of ethanol intake on lipoproteins and atherosclerosisEliot A Brinton
Department of Cardiovascular Genetics, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
Curr Opin Lipidol 21:346-51. 2010..This article reviews published studies regarding effects of ethanol intake on lipoprotein levels and function as they relate to atherosclerosis, with special emphasis on recent publications in the past 2 years...
Can menopausal hormone therapy prevent coronary heart disease?Eliot A Brinton
Cardiovascular Genetics, University of Utah School of Medicine, Salt Lake City, UT 84108, USA
Trends Endocrinol Metab 19:206-12. 2008..We call for new research on this question, and an evidence-based review of existing recommendations for MHT...
Novel pathways for glycaemic control in type 2 diabetes: focus on bile acid modulationEliot A Brinton
Cardiovascular Genetics, University of Utah School of Medicine, Salt Lake City, UT 84108, USA
Diabetes Obes Metab 10:1004-11. 2008..There is renewed interest in the use of bile acid sequestrants in individuals with type 2 diabetes, most of whom would benefit from additional reductions in both LDL-cholesterol and glycaemia...
Plasma triglycerides and type III hyperlipidemia are independently associated with premature familial coronary artery diseasePaul N Hopkins
Cardiovascular Genetics, Department of Internal Medicine, Cardiology Division, University of Utah School of Medicine, 410 Chipeta Way, Salt Lake City, UT 84108, USA
J Am Coll Cardiol 45:1003-12. 2005..This study was designed to explore contributions of plasma total triglycerides (TGs) and type III hyperlipidemia to the risk of premature familial coronary artery disease (CAD)...
Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obeseTed D Adams
Department of Internal Medicine, Cardiovascular Genetics Division, University of Utah, Salt Lake City, Utah, USA
Obesity (Silver Spring) 18:121-30. 2010....
Effects of ethanol intake on lipoproteinsEliot A Brinton
Utah Foundation for Biomedical Research, Salt Lake City, UT, USA
Curr Atheroscler Rep 14:108-14. 2012..Application of these findings in clinical practice remains problematic, however, due to the lack of randomized, controlled clinical trials of ethanol and due to the potential hazards of ethanol consumption...
Controversies in dyslipidemias: atheroprevention in diabetes and insulin resistanceEliot A Brinton
Metabolism Section, Cardiology Division, University of Utah, Room 4A100, 30 North 1900 East, Salt Lake City, Utah 84132, USA
Ann N Y Acad Sci 1055:159-78. 2005..Finally, strategies for maintaining glucose control and the role of inflammation associated with MS/IR and CVD are described...
Altered composition of triglyceride-rich lipoproteins and coronary artery disease in a large case-control studyPaul N Hopkins
Cardiovascular Genetics Research, Department of Internal Medicine, Cardiology Division, University of Utah School of Medicine, Salt Lake City, UT 84108, USA
Atherosclerosis 207:559-66. 2009..30 with TG>150mg/dL) indicative of atherogenic remnant accumulation (type III hyperlipidemia). However, virtually no reports are available which examine potential associations between CAD and VLDL-C/TG at the lower end of the spectrum...
Is the estrogen controversy over? Deconstructing the Women's Health Initiative study: a critical evaluation of the evidenceS Mitchell Harman
Kronos Longevity Research Institute, 2222 E Highland, Ste 220, Phoenix, AZ 85016, USA
Ann N Y Acad Sci 1052:43-56. 2005..It will examine surrogate end points as well as risk factors for atherosclerosis...
Postmenopausal hormone therapy: new questions and the case for new clinical trialsJoAnn E Manson
Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
Menopause 13:139-47. 2006....
Women, hormones, and clinical trials: a beginning, not an endVirginia M Miller
J Appl Physiol 99:381-3. 2005
Is the WHI relevant to HRT started in the perimenopause?S Mitchell Harman
Kronos Longevity Research Institute, Phoenix, AZ, USA
Endocrine 24:195-202. 2004..Furthermore, animal and clinical evidence supports the use of lower doses of estrogen than were employed in the WHI in older/longer postmenopausal women...
Triglyceride-rich lipoprotein remnant levels and metabolism: time to adopt these orphan risk factors?Eliot A Brinton
J Am Coll Cardiol 43:2233-5. 2004
Estrogen receptor 1 variants and coronary artery disease: shedding light into a murky poolPaul N Hopkins
JAMA 290:2317-9. 2003
Lipid abnormalities in the metabolic syndromeEliot A Brinton
Carl T. Hayden VA Medical Center, Section of Metabolism, Endocrinology, and Nutrition, Department of Internal Medicine, 111 E, 650 East Indian School Road, Phoenix, AZ 85012, USA
Curr Diab Rep 3:65-72. 2003..These steps are now more feasible and more clearly desirable than ever before. Statins alone greatly reduce atherosclerosis risk, but combination lipid therapy is often required for optimal dyslipidemia management and atheroprevention...
Increased intra-abdominal fat may lower HDL levels by increasing the fractional catabolic rate of Lp A-I in postmenopausal womenZoltan Vajo
Section of Metabolism, Endocrinology and Nutrition, Department of Medicine, Carl T. Hayden VA Medical Center, 111E, 650 E Indian School Road, Phoenix, AZ 85012, USA
Atherosclerosis 160:495-501. 2002..84, P=0.04). We conclude that intra-abdominal fat may lower HDL levels by increasing the FCR of Lp A-I, suggesting a mechanism by which central adiposity may be proatherogenic...
