Charles Bridges

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Global cardiac-specific transgene expression using cardiopulmonary bypass with cardiac isolation
    Charles R Bridges
    Department of Surgery, University of Pennsylvania Medical Center, Philadelphia, USA
    Ann Thorac Surg 73:1939-46. 2002
  2. ncbi request reprint Association between indices of prosthesis internal orifice size and operative mortality after isolated aortic valve replacement
    Charles R Bridges
    Department of Surgery, The University of Pennsylvania Health System, Philadelphia, PA, USA
    J Thorac Cardiovasc Surg 133:1012-21. 2007
  3. ncbi request reprint Invited commentary
    Charles R Bridges
    Division of Cardiothoracic Surgery, University of Pennsylvania Medical Center, The Farm Journal Building, 230 W Washington Sq, 3rd Floor, Philadelphia, PA 19106, USA
    Ann Thorac Surg 82:1405-6. 2006
  4. ncbi request reprint Guidelines for the clinical use of transmyocardial laser revascularization
    Charles R Bridges
    Department of Surgery, the University of Pennsylvania Health System Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Semin Thorac Cardiovasc Surg 18:68-73. 2006
  5. ncbi request reprint Invited commentary
    Charles R Bridges
    Division of Cardiothoracic Surgery, University of Pennsylvania Medical Center, The Farm Journal Building, 230 W Washington Square, 3rd Floor, Philadelphia, PA 19106, USA
    Ann Thorac Surg 85:93. 2008
  6. ncbi request reprint Efficient myocyte gene delivery with complete cardiac surgical isolation in situ
    Charles R Bridges
    Department of Surgery of the University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    J Thorac Cardiovasc Surg 130:1364. 2005
  7. ncbi request reprint The Society of Thoracic Surgeons practice guideline series: transmyocardial laser revascularization
    Charles R Bridges
    Division of Cardiothoracic Surgery, Department of Surgery, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    Ann Thorac Surg 77:1494-502. 2004
  8. ncbi request reprint Cardiac surgery in African Americans
    Charles R Bridges
    Department of Surgery, the University of Pennsylvania Health System and Hospital of the University of Pennsylvania, Philadelphia, PA 19106, USA
    Ann Thorac Surg 76:S1356-62. 2003
  9. ncbi request reprint Fungal prosthetic mitral valve endocarditis caused by Scopulariopsis species: case report and review of the literature
    Alice May B Isidro
    Department of Surgery, The University of Pennsylvania Health System, Pennsylvania Hospital, Philadelphia, PA 19104, USA
    J Thorac Cardiovasc Surg 131:1181-3. 2006
  10. ncbi request reprint Perioperative blood transfusion and blood conservation in cardiac surgery: the Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists clinical practice guideline
    Victor A Ferraris
    Ann Thorac Surg 83:S27-86. 2007

Research Grants

  1. Retrograde In Situ Isolated Cardiac Gene Delivery
    Charles Bridges; Fiscal Year: 2004
  2. Translational studies in Heart Failure Gene Therapy
    Charles Bridges; Fiscal Year: 2009
  3. Translational studies in Heart Failure Gene Therapy
    Charles R Bridges; Fiscal Year: 2010

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Global cardiac-specific transgene expression using cardiopulmonary bypass with cardiac isolation
    Charles R Bridges
    Department of Surgery, University of Pennsylvania Medical Center, Philadelphia, USA
    Ann Thorac Surg 73:1939-46. 2002
    ..To address this problem, we developed a novel cannulation technique that achieves efficient isolation of the heart in situ using separate cardiopulmonary bypass (CPB) circuits for the heart and body in dogs...
  2. ncbi request reprint Association between indices of prosthesis internal orifice size and operative mortality after isolated aortic valve replacement
    Charles R Bridges
    Department of Surgery, The University of Pennsylvania Health System, Philadelphia, PA, USA
    J Thorac Cardiovasc Surg 133:1012-21. 2007
    ..Indices examined included projected in vivo effective orifice area and geometric orifice area, with patient size defined as body surface area...
  3. ncbi request reprint Invited commentary
    Charles R Bridges
    Division of Cardiothoracic Surgery, University of Pennsylvania Medical Center, The Farm Journal Building, 230 W Washington Sq, 3rd Floor, Philadelphia, PA 19106, USA
    Ann Thorac Surg 82:1405-6. 2006
  4. ncbi request reprint Guidelines for the clinical use of transmyocardial laser revascularization
    Charles R Bridges
    Department of Surgery, the University of Pennsylvania Health System Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Semin Thorac Cardiovasc Surg 18:68-73. 2006
    ..It also may be effective as an adjunct to CABG for a subset of patients with angina who cannot be completely revascularized surgically...
  5. ncbi request reprint Invited commentary
    Charles R Bridges
    Division of Cardiothoracic Surgery, University of Pennsylvania Medical Center, The Farm Journal Building, 230 W Washington Square, 3rd Floor, Philadelphia, PA 19106, USA
    Ann Thorac Surg 85:93. 2008
  6. ncbi request reprint Efficient myocyte gene delivery with complete cardiac surgical isolation in situ
    Charles R Bridges
    Department of Surgery of the University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    J Thorac Cardiovasc Surg 130:1364. 2005
    ....
  7. ncbi request reprint The Society of Thoracic Surgeons practice guideline series: transmyocardial laser revascularization
    Charles R Bridges
    Division of Cardiothoracic Surgery, Department of Surgery, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    Ann Thorac Surg 77:1494-502. 2004
    ....
  8. ncbi request reprint Cardiac surgery in African Americans
    Charles R Bridges
    Department of Surgery, the University of Pennsylvania Health System and Hospital of the University of Pennsylvania, Philadelphia, PA 19106, USA
    Ann Thorac Surg 76:S1356-62. 2003
    ..In this context we interpret both terms to refer to Americans of African descent. Similarly, we use the term "white" or "Caucasian" interchangeably to refer to Americans of European descent...
  9. ncbi request reprint Fungal prosthetic mitral valve endocarditis caused by Scopulariopsis species: case report and review of the literature
    Alice May B Isidro
    Department of Surgery, The University of Pennsylvania Health System, Pennsylvania Hospital, Philadelphia, PA 19104, USA
    J Thorac Cardiovasc Surg 131:1181-3. 2006
  10. ncbi request reprint Perioperative blood transfusion and blood conservation in cardiac surgery: the Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists clinical practice guideline
    Victor A Ferraris
    Ann Thorac Surg 83:S27-86. 2007
    ..Blood must be viewed as a scarce resource that carries risks and benefits. A careful review of available evidence can provide guidelines to allocate this valuable resource and improve patient outcomes...
  11. ncbi request reprint Bedside tool for predicting the risk of postoperative dialysis in patients undergoing cardiac surgery
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 114:2208-16; quiz 2208. 2006
    ..Estimation of an individual patient's risk for postoperative dialysis can support informed clinical decision making and patient counseling...
  12. ncbi request reprint From controlled trials to clinical practice: monitoring transmyocardial revascularization use and outcomes
    Eric D Peterson
    Duke Clinical Research Institute, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 42:1611-6. 2003
    ..We also identified important risk factors for TMR and compared outcomes of TMR combined with coronary artery bypass graft surgery (TMR + CABG) versus bypass alone in patients receiving incomplete revascularization...
  13. ncbi request reprint Uniform scale-independent gene transfer to striated muscle after transvenular extravasation of vector
    Leonard T Su
    Department of Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    Circulation 112:1780-8. 2005
    ..Previous studies in large-animal models have revealed a trade-off between the efficiency of gene transfer and the inherent safety of the required surgical and pharmacological interventions to achieve this...
  14. ncbi request reprint Impact of renal dysfunction on outcomes of coronary artery bypass surgery: results from the Society of Thoracic Surgeons National Adult Cardiac Database
    William A Cooper
    Division of Cardiothoracic Surgery, Joseph B Whitehead Department of Surgery, Carlyle Fraser Heart Center, Emory University School of Medicine, Atlanta, GA, USA
    Circulation 113:1063-70. 2006
    ..The purpose of this study was to compare outcomes in patients undergoing CABG with a range from normal renal function to dependence on dialysis...
  15. ncbi request reprint Minimally invasive cardiac surgery using a flexible aortic clamp
    B Reddy Dandolu
    University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    Heart Surg Forum 10:E428-30; discusson E430. 2007
    ..There have been no strokes, no mortalities, and no episodes of limb ischemia in our series. No patient has required reoperation...
  16. ncbi request reprint ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise th
    Jeffrey L Anderson
    J Am Coll Cardiol 50:e1-e157. 2007
  17. ncbi request reprint ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise th
    Jeffrey L Anderson
    Circulation 116:e148-304. 2007
  18. ncbi request reprint Cardiovascular function in normotensive offspring of persons with essential hypertension and black race
    Emile R Mohler
    Division of Cardiovascular Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Clin Hypertens (Greenwich) 9:506-12. 2007
    ..These same studies demonstrated some early changes in vascular function based on sex...
  19. ncbi request reprint Bicuspidization of the tricuspid valve for the treatment of posterior leaflet endocarditis: a case report
    Alice B Isidro
    Department of Surgery, University of Pennsylvania Health System, Pennsylvania Hospital, Philadelphia, Pennsylvania 19104, USA
    Heart Surg Forum 10:E129-30. 2007
    ....
  20. ncbi request reprint Valid comparisons of antifibrinolytic agents used in cardiac surgery
    Charles R Bridges
    Circulation 115:2790-2. 2007
  21. ncbi request reprint The Society of Thoracic Surgeons practice guideline series: aspirin and other antiplatelet agents during operative coronary revascularization (executive summary)
    Victor A Ferraris
    University of Kentucky Chandler Medical Center, Lexington, Kentucky 40536, USA
    Ann Thorac Surg 79:1454-61. 2005
  22. ncbi request reprint Homograft aortic root replacement during pregnancy
    Kapil Gopal
    Department of Surgery, Pennsylvania Hospital, Philadelphia 19106, USA
    Ann Thorac Surg 74:243-5. 2002
    ..Aortic root replacement with an aortic homograft in a 34-year-old pregnant woman with bacterial endocarditis at 18 weeks gestation is presented. Fetal echocardiography during and after bypass was employed...
  23. ncbi request reprint Guidelines for reporting data and outcomes for the surgical treatment of atrial fibrillation
    Richard J Shemin
    Division of Cardiothoracic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Ann Thorac Surg 83:1225-30. 2007
    ..Thus, more reliable evaluation and comparisons of results will advance our knowledge and further the development and application of these procedures...
  24. ncbi request reprint Cardiac surgery in nonagenarians and centenarians
    Charles R Bridges
    Department of Surgery, University of Pennsylvania Medical Center, Philadelphia, PA, USA
    J Am Coll Surg 197:347-56; discussion 356-7. 2003
    ..Nonagenarians and centenarians are a rapidly growing segment of the population. No previous study has used a national database to compare outcomes in these patients to those of other groups undergoing cardiac surgical procedures...
  25. ncbi request reprint Myosin gene mutation correlates with anatomical changes in the human lineage
    Hansell H Stedman
    Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Nature 428:415-8. 2004
    ..This represents the first proteomic distinction between humans and chimpanzees that can be correlated with a traceable anatomic imprint in the fossil record...
  26. ncbi request reprint The Society of Thoracic Surgeons Practice Guideline Series: Antibiotic Prophylaxis in Cardiac Surgery, Part I: Duration
    Fred H Edwards
    Division of Cardiothoracic Surgery, University of Florida, Jacksonville, Florida 32209, USA
    Ann Thorac Surg 81:397-404. 2006
  27. ncbi request reprint Aprotinin in cardiac surgery
    Victor A Ferraris
    N Engl J Med 354:1953-7; author reply 1953-7. 2006
  28. ncbi request reprint Relationship between race and mortality and morbidity after valve replacement surgery
    Nyali E Taylor
    Department of Surgery, The University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    Circulation 111:1305-12. 2005
    ..We could not identify a previous study that used a multivariable model to evaluate the association between race and operative mortality after AVR or MVR...

Research Grants7

  1. Retrograde In Situ Isolated Cardiac Gene Delivery
    Charles Bridges; Fiscal Year: 2004
    ..Further development of this approach may ultimately lead to the development of clinically relevant techniques of therapeutic cardiac gene delivery for the treatment of heart failure of diverse etiologies. ..
  2. Translational studies in Heart Failure Gene Therapy
    Charles Bridges; Fiscal Year: 2009
    ..Successful completion of this study may lead to alternatives to heart transplantation and permanent mechanical assist devices in the treatment of end stage heart failure. ..
  3. Translational studies in Heart Failure Gene Therapy
    Charles R Bridges; Fiscal Year: 2010
    ..Successful completion of this study may lead to alternatives to heart transplantation and permanent mechanical assist devices in the treatment of end stage heart failure. ..