J A Bridge

Summary

Affiliation: University of Nebraska Medical Center
Country: USA

Publications

  1. ncbi Trisomies 8 and 20 characterize a subgroup of benign fibrous lesions arising in both soft tissue and bone
    J A Bridge
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198 5440, USA
    Am J Pathol 154:729-33. 1999
  2. ncbi Regulation of MMP-9 (92 kDa type IV collagenase/gelatinase B) expression in stromal cells of human giant cell tumor of bone
    V H Rao
    Meyer Rehabilitation Institute and Department of Pediatrics, University of Nebraska Medical Center, Omaha 68198, USA
    Clin Exp Metastasis 15:400-9. 1997
  3. ncbi Cytogenetic analysis of a malignant triton tumor and a malignant peripheral nerve sheath tumor and a review of the literature
    E N McComb
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68198 5440, USA
    Cancer Genet Cytogenet 91:8-12. 1996
  4. ncbi Fusion of the ALK gene to the clathrin heavy chain gene, CLTC, in inflammatory myofibroblastic tumor
    J A Bridge
    Department of Pathology, Center for Human Molecular Genetics, 983135 University of Nebraska Medical Center, Omaha, NE 68198, USA
    Am J Pathol 159:411-5. 2001
  5. ncbi Extra copies of chromosomes 7, 8, 12, 19, and 21 are recurrent in adamantinoma
    M Kanamori
    Departments of Pathology and Microbiology, Center for Human Molecular Genetics, University of Nebraska Medical Center, Omaha, Nebraska, USA
    J Mol Diagn 3:16-21. 2001
  6. ncbi Recurrent chromosomal imbalances and structurally abnormal breakpoints within complex karyotypes of malignant peripheral nerve sheath tumour and malignant triton tumour: a cytogenetic and molecular cytogenetic study
    R S Bridge
    Department of Pathology, 983135 Nebraska Medical Center, Omaha, NE 68198-3135, USA
    J Clin Pathol 57:1172-8. 2004
  7. ncbi Translocation t(1;3)(p36.3;q25) is a nonrandom aberration in epithelioid hemangioendothelioma
    M R Mendlick
    Departments of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198-3135, USA
    Am J Surg Pathol 25:684-7. 2001
  8. ncbi Cytogenetic instability, predominantly involving chromosome 1, is characteristic of elastofibroma
    E N McComb
    Departments of Pathology and Microbiology, University of Nebraska Medical Center, 68198-3135, Omaha, NE, USA
    Cancer Genet Cytogenet 126:68-72. 2001
  9. ncbi Novel genomic imbalances in embryonal rhabdomyosarcoma revealed by comparative genomic hybridization and fluorescence in situ hybridization: an intergroup rhabdomyosarcoma study
    J A Bridge
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198 3135, USA
    Genes Chromosomes Cancer 27:337-44. 2000
  10. ncbi Interleukin-1beta upregulates MMP-9 expression in stromal cells of human giant cell tumor of bone
    V H Rao
    Center for Human Molecular Genetics, Munroe Meyer Institute for Genetics and Rehabilitation, and the Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68198, USA
    J Interferon Cytokine Res 19:1207-17. 1999

Collaborators

Detail Information

Publications11

  1. ncbi Trisomies 8 and 20 characterize a subgroup of benign fibrous lesions arising in both soft tissue and bone
    J A Bridge
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198 5440, USA
    Am J Pathol 154:729-33. 1999
    ..Our findings demonstrate that trisomy 8 and trisomy 20 are also nonrandom aberrations in histologically similar, but clinically distinct, benign fibrous lesions of bone...
  2. ncbi Regulation of MMP-9 (92 kDa type IV collagenase/gelatinase B) expression in stromal cells of human giant cell tumor of bone
    V H Rao
    Meyer Rehabilitation Institute and Department of Pediatrics, University of Nebraska Medical Center, Omaha 68198, USA
    Clin Exp Metastasis 15:400-9. 1997
    ..This suggests that multinucleated giant cells in primary cultures secrete a factor(s) that stimulates stromal cells to produce MMP-9, which, in turn, may contribute to the aggressive behavior of GCT...
  3. ncbi Cytogenetic analysis of a malignant triton tumor and a malignant peripheral nerve sheath tumor and a review of the literature
    E N McComb
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68198 5440, USA
    Cancer Genet Cytogenet 91:8-12. 1996
    ..The genes for peripheral neurofibromatosis (NF-1) and central neurofibromatosis (NF-2) have been mapped to these two chromosomes respectively...
  4. ncbi Fusion of the ALK gene to the clathrin heavy chain gene, CLTC, in inflammatory myofibroblastic tumor
    J A Bridge
    Department of Pathology, Center for Human Molecular Genetics, 983135 University of Nebraska Medical Center, Omaha, NE 68198, USA
    Am J Pathol 159:411-5. 2001
    ..One of these cases exhibited a 2;17 translocation in addition to other karyotypic anomalies [46,XX,t(2;17)(p23;q23),add(16)(q24)]...
  5. ncbi Extra copies of chromosomes 7, 8, 12, 19, and 21 are recurrent in adamantinoma
    M Kanamori
    Departments of Pathology and Microbiology, Center for Human Molecular Genetics, University of Nebraska Medical Center, Omaha, Nebraska, USA
    J Mol Diagn 3:16-21. 2001
    ..Adamantinoma may be confused with a variety of primary and metastatic epithelial and mesenchymal neoplasms. Observation of these aneuploidies may be useful in establishing the diagnosis of adamantinoma...
  6. ncbi Recurrent chromosomal imbalances and structurally abnormal breakpoints within complex karyotypes of malignant peripheral nerve sheath tumour and malignant triton tumour: a cytogenetic and molecular cytogenetic study
    R S Bridge
    Department of Pathology, 983135 Nebraska Medical Center, Omaha, NE 68198-3135, USA
    J Clin Pathol 57:1172-8. 2004
    ..FISH analysis was negative for amplification. CONCLUSIONS: These cytogenetic and molecular cytogenetic findings expand the knowledge of chromosomal alterations in MPNST and MTT, and point to possible recurring regions of interest...
  7. ncbi Translocation t(1;3)(p36.3;q25) is a nonrandom aberration in epithelioid hemangioendothelioma
    M R Mendlick
    Departments of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198-3135, USA
    Am J Surg Pathol 25:684-7. 2001
    ..Identification of the 1;3 translocation may be useful diagnostically. Should additional studies confirm these data, this could lead to the identification of the gene(s) central to this neoplastic process...
  8. ncbi Cytogenetic instability, predominantly involving chromosome 1, is characteristic of elastofibroma
    E N McComb
    Departments of Pathology and Microbiology, University of Nebraska Medical Center, 68198-3135, Omaha, NE, USA
    Cancer Genet Cytogenet 126:68-72. 2001
    ..The observation of clonal abnormalities in elastofibroma suggests that this lesion may represent a neoplastic rather than a reactive process...
  9. ncbi Novel genomic imbalances in embryonal rhabdomyosarcoma revealed by comparative genomic hybridization and fluorescence in situ hybridization: an intergroup rhabdomyosarcoma study
    J A Bridge
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198 3135, USA
    Genes Chromosomes Cancer 27:337-44. 2000
    ..In summary, CGH and FISH analyses of 12 E-RMS specimens revealed novel genomic imbalances that may be useful in directing further molecular studies for the determination of E-RMS critically involved genes...
  10. ncbi Interleukin-1beta upregulates MMP-9 expression in stromal cells of human giant cell tumor of bone
    V H Rao
    Center for Human Molecular Genetics, Munroe Meyer Institute for Genetics and Rehabilitation, and the Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68198, USA
    J Interferon Cytokine Res 19:1207-17. 1999
    ....
  11. ncbi Clonal karyotypic abnormalities of the hereditary multiple exostoses chromosomal loci 8q24.1 (EXT1) and 11p11-12 (EXT2) in patients with sporadic and hereditary osteochondromas
    J A Bridge
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68198 5440, USA
    Cancer 82:1657-63. 1998
    ..1 (EXT1), 11p11-12 (EXT2), and 19p (EXT3). Constitutional chromosomal microdeletions of 8q24.1 and 11p11-12 are features of the Langer-Giedion and DEFECT-11 syndromes, respectively. Cytogenetic studies of osteochondroma are rare...