Helen M Brew

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Systematic variation of potassium current amplitudes across the tonotopic axis of the rat medial nucleus of the trapezoid body
    Helen M Brew
    Department of Cell Physiology and Pharmacology, University of Leicester, P O Box 138, Leicester LE1 9HN, UK
    Hear Res 206:116-32. 2005
  2. pmc Hyperexcitability and reduced low threshold potassium currents in auditory neurons of mice lacking the channel subunit Kv1.1
    Helen M Brew
    The Virginia Merrill Bloedel Hearing Research Center and the Department of Otolaryngology Head and Neck Surgery, Box 357923, University of Washington School of Medicine, Seattle, WA 98195, USA
    J Physiol 548:1-20. 2003
  3. ncbi request reprint Seizures and reduced life span in mice lacking the potassium channel subunit Kv1.2, but hypoexcitability and enlarged Kv1 currents in auditory neurons
    Helen M Brew
    Virginia Merrill Bloedel Hearing Research Center, Box 357923, University of Washington, Seattle, WA 98195 7923, USA
    J Neurophysiol 98:1501-25. 2007

Detail Information

Publications3

  1. ncbi request reprint Systematic variation of potassium current amplitudes across the tonotopic axis of the rat medial nucleus of the trapezoid body
    Helen M Brew
    Department of Cell Physiology and Pharmacology, University of Leicester, P O Box 138, Leicester LE1 9HN, UK
    Hear Res 206:116-32. 2005
    ....
  2. pmc Hyperexcitability and reduced low threshold potassium currents in auditory neurons of mice lacking the channel subunit Kv1.1
    Helen M Brew
    The Virginia Merrill Bloedel Hearing Research Center and the Department of Otolaryngology Head and Neck Surgery, Box 357923, University of Washington School of Medicine, Seattle, WA 98195, USA
    J Physiol 548:1-20. 2003
    ..2 and/or Kv1.6 (also DTX-sensitive). DTX increased excitability further in the already hyperexcitable -/- MNTB neurons, suggesting that -/- IKL limited excitability despite its reduced amplitude in the absence of Kv1.1 subunits...
  3. ncbi request reprint Seizures and reduced life span in mice lacking the potassium channel subunit Kv1.2, but hypoexcitability and enlarged Kv1 currents in auditory neurons
    Helen M Brew
    Virginia Merrill Bloedel Hearing Research Center, Box 357923, University of Washington, Seattle, WA 98195 7923, USA
    J Neurophysiol 98:1501-25. 2007
    ..If channel voltage dependence is determined by how many Kv1.2 subunits each contains, neurons might be able to fine-tune their excitability by adjusting the Kv1.1:Kv1.2 balance rather than altering Kv1 channel density...