Research Topics
| D A BrentSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Firearms and suicideD A Brent
Division of Child and Adolescent Psychiatry, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Suite 112, Pittsburgh, PA 15213, USA
Ann N Y Acad Sci 932:225-39; discussion; 239-40. 2001..The convergent finding from this wide range of studies is that there is a strong relationship between firearms in the home and risk for suicide, most firmly established in the United States...
Age- and sex-related risk factors for adolescent suicideD A Brent
Western Psychiatric Institute and Clinic, Pittsburgh
J Am Acad Child Adolesc Psychiatry 38:1497-505. 1999..To examine the impact of age and sex on adolescent suicide risk...
Familial pathways to early-onset suicide attempt: risk for suicidal behavior in offspring of mood-disordered suicide attemptersDavid A Brent
Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Arch Gen Psychiatry 59:801-7. 2002..Although adoption, twin, and family studies have shown that suicidal behavior is familial, the risk factors for familial transmission from parent to child remain unclear...
Compliance with recommendations to remove firearms in families participating in a clinical trial for adolescent depressionD A Brent
Division of Child and Adolescent Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
J Am Acad Child Adolesc Psychiatry 39:1220-6. 2000..To assess the rate and correlates of compliance with clinicians' recommendations to remove firearms from the homes of depressed adolescents participating in a clinical trial...
Assessment and treatment of the youthful suicidal patientD A Brent
Division of Child and Adolescent Psychiatry, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Ann N Y Acad Sci 932:106-28; discussion 128-31. 2001..Further research is necessary to identify the most effective approaches to the treatment of adolescent suicide attempters...
Subsyndromal depression in adolescents after a brief psychotherapy trial: course and outcomeD A Brent
Division of Child and Adolescent Psychiatry, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Affect Disord 63:51-8. 2001..Since treatment trials of adolescent MDD often result in subsyndromal depression as the outcome, the long-term course of these youth would be useful to understand...
Clinical outcome after short-term psychotherapy for adolescents with major depressive disorderB Birmaher
Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, PA 15213, USA
Arch Gen Psychiatry 57:29-36. 2000..However, the long-term impact of brief psychosocial interventions on the course of adolescent depression is not well established...
Familial pathways to early-onset suicidal behavior: familial and individual antecedents of suicidal behaviorNadine M Melhem
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Am J Psychiatry 164:1364-70. 2007..The authors sought to identify clinical predictors of new-onset suicidal behavior in children of parents with a history of mood disorder and suicidal behavior...
Psychometric properties of the Screen for Child Anxiety Related Emotional Disorders (SCARED): a replication studyB Birmaher
Division of Child Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Am Acad Child Adolesc Psychiatry 38:1230-6. 1999..To replicate and extend work on the psychometric properties of the Screen for Child Anxiety Related Emotional Disorders (SCARED), a child and parent self-report instrument used to screen for children with anxiety disorders...
Growth hormone secretion in children and adolescents at high risk for major depressive disorderB Birmaher
Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
Arch Gen Psychiatry 57:867-72. 2000..In this study, we sought to determine whether GH secretion is similarly altered in children and adolescents who had never experienced depression but were at high risk of developing depression...
Phenomenology of panic disorder in youthRasim Somer Diler
Division of Child Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
Depress Anxiety 20:39-43. 2004..Subjects with both panic and non-panic anxiety disorders were more likely to have comorbid major depression and conduct disorders than those with other non-anxiety disorders...
Cognitive and family therapies for adolescent depression: treatment specificity, mediation, and moderationD J Kolko
Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
J Consult Clin Psychol 68:603-14. 2000..As in adult studies, relatively few areas of treatment specificity or mediation were identified. The implications of these findings for clinical treatment and research in adolescent depression are discussed...
Antidepressants and pediatric depression--the risk of doing nothingDavid A Brent
Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, USA
N Engl J Med 351:1598-601. 2004
Emergent suicidality in a clinical psychotherapy trial for adolescent depressionJeffrey A Bridge
Western Psychiatric Institute and Clinic, Child and Adolescent Psychiatry, 3811 O'Hara St, BFT 311, Pittsburgh, PA 15213-2592, USA
Am J Psychiatry 162:2173-5. 2005..To evaluate accurately the role of treatment in emergent suicidality, it is important to assess self-reported suicidality at intake and to balance treatment groups on this key predictor of emergent suicidality...
Antecedents and sequelae of sudden parental death in offspring and surviving caregiversNadine M Melhem
Western Psychiatric Institute and Clinic and the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Arch Pediatr Adolesc Med 162:403-10. 2008..To examine the psychiatric antecedents that put parents at risk for early death, and the psychological sequelae of bereavement in offspring and caregivers...
The stressful life events schedule for children and adolescents: development and validationDouglas E Williamson
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Psychiatry Res 119:225-41. 2003..48). The results of this study indicate that the SLES has good psychometric properties. The SLES is a useful, cost-effective tool for assessing stressful life events in children and adolescents...
Platelet serotonin reuptake inhibition and response to SSRIs in depressed adolescentsDavid A Axelson
Western Psychiatric Institute and Clinic, 3811 O'Hara St, Pittsburgh, PA 15213, USA
Am J Psychiatry 162:802-4. 2005..CONCLUSIONS: Platelet serotonin reuptake inhibition may be an appropriate surrogate biological marker for the pharmacodynamic activity of SSRIs in depressed adolescents...
Family genetic studies, suicide, and suicidal behaviorDavid A Brent
Child and Adolescent Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Am J Med Genet C Semin Med Genet 133:13-24. 2005..Shared environment effects such as abuse, imitation, or transmission of psychopathology are other possible explanations...
Steady-state pharmacokinetics of bupropion SR in juvenile patientsW Burleson Daviss
Western Psychiatric Institute and Clinic, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Am Acad Child Adolesc Psychiatry 44:349-57. 2005..To examine the steady-state pharmacokinetic properties of bupropion sustained release (SR) and their potential developmental differences in youths...
Brief interpersonal psychotherapy for depressed mothers whose children are receiving psychiatric treatmentHolly A Swartz
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, USA
Am J Psychiatry 165:1155-62. 2008....
Steady-state clinical pharmacokinetics of bupropion extended-release in youthsW Burleson Daviss
Western Psychiatric Institute and Clinic, University of Pittsburgh, USA
J Am Acad Child Adolesc Psychiatry 45:1503-9. 2006..To examine in children and adolescents the 24-hour, steady-state clinical pharmacokinetics of an extended-release (XL) formulation of bupropion (Wellbutrin XL)...
Familial transmission of suicidal behaviorDavid A Brent
Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Psychiatr Clin North Am 31:157-77. 2008..However, so-called family environmental factors often are related to risk factors that are heritable. Conversely, genetic factors exert their impact on depression and suicidal behavior via interaction with a stressful environment...
Sleep disturbance preceding completed suicide in adolescentsTina R Goldstein
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
J Consult Clin Psychol 76:84-91. 2008..Sleep difficulties should therefore be carefully considered in prevention and intervention efforts for adolescents at risk for suicide...
History of suicide attempts in pediatric bipolar disorder: factors associated with increased riskTina R Goldstein
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Bipolar Disord 7:525-35. 2005..Despite evidence indicating high morbidity associated with pediatric bipolar disorder (BP), little is known about the prevalence and clinical correlates of suicidal behavior among this population...
Acute antidepressant response and plasma levels of bupropion and metabolites in a pediatric-aged sample: an exploratory studyW Burleson Daviss
Western Psychiatric Institute and Clinic, Pittsburgh, PA, and the University of Pittsburgh, Pittsburgh, PA 15213, USA
Ther Drug Monit 28:190-8. 2006..009). These preliminary findings suggest that plasma levels of bupropion and metabolites, particularly hydroxybupropion, may predict acute antidepressant response in depressed youths taking bupropion SR...
Dialectical behavior therapy for adolescents with bipolar disorder: a 1-year open trialTina R Goldstein
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
J Am Acad Child Adolesc Psychiatry 46:820-30. 2007..To describe an adapted version of dialectical behavior therapy for adolescents with bipolar disorder...
Treatment-resistant depression in adolescents: recognition and managementDavid A Brent
Department of Child and Adolescent Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara Street, BFT 311, Pittsburgh, PA 15213 2592, USA
Child Adolesc Psychiatr Clin N Am 15:1015-34, x. 2006....
Glad for what TADS adds, but many TADS grads still sadDavid A Brent
Department of Psychiatry at Western Psychiatric Institute, PA 45213, USA
J Am Acad Child Adolesc Psychiatry 45:1461-4. 2006
Recent trends in suicide among U.S. adolescent males, 1992-2001Jeffrey A Bridge
University of Pittsburgh School of Medicine, 3811 O'Hara Street, Pittsburgh, PA 15213-2592, USA
Psychiatr Serv 56:522. 2005
Familial transmission of mood disorders: convergence and divergence with transmission of suicidal behaviorDavid A Brent
Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Am Acad Child Adolesc Psychiatry 43:1259-66. 2004..In this study, the authors examine the factors associated with the familial transmission of these two related conditions to learn which are shared or unique risk factors for familial transmission...
Sertraline pharmacokinetics and dynamics in adolescentsDavid A Axelson
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213, USA
J Am Acad Child Adolesc Psychiatry 41:1037-44. 2002..To determine the pharmacokinetics of sertraline in adolescents and assess its effect on a surrogate marker of serotonin transport...
Fluoxetine for the treatment of childhood anxiety disordersBoris Birmaher
Department of Child Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Am Acad Child Adolesc Psychiatry 42:415-23. 2003..To assess the efficacy and tolerability of fluoxetine for the acute treatment of children and adolescents with generalized anxiety disorder, separation anxiety disorder, and/or social phobia...
Peripubertal suicide attempts in offspring of suicide attempters with siblings concordant for suicidal behaviorDavid A Brent
Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Am J Psychiatry 160:1486-93. 2003....
Major depressive disorder in adolescents exposed to a friend's suicideJeffrey A Bridge
Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Am Acad Child Adolesc Psychiatry 42:1294-300. 2003....
The Treatment of Adolescent Suicide Attempters study (TASA): predictors of suicidal events in an open treatment trialDavid A Brent
University of Pittsburgh, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Am Acad Child Adolesc Psychiatry 48:987-96. 2009..To identify the predictors of suicidal events and attempts in adolescent suicide attempters with depression treated in an open treatment trial...
Lifetime history of sexual abuse, clinical presentation, and outcome in a clinical trial for adolescent depressionRémy P Barbe
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
J Clin Psychiatry 65:77-83. 2004..To investigate the impact of sexual abuse on clinical presentation and treatment outcome in depressed adolescents...
Predictors of spontaneous and systematically assessed suicidal adverse events in the treatment of SSRI-resistant depression in adolescents (TORDIA) studyDavid A Brent
University of Pittsburgh School of Medicine, Western University School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara St, Suite 112, Pittsburgh, PA 15213 2593, USA
Am J Psychiatry 166:418-26. 2009..The authors sought to identify predictors of self-harm adverse events in treatment-resistant, depressed adolescents during the first 12 weeks of treatment...
Recurrent abdominal pain, anxiety, and depression in primary careJohn V Campo
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Pediatrics 113:817-24. 2004..Our aim was to determine whether RAP is associated with psychiatric symptoms and disorders, anxious temperament, and functional impairment in pediatric primary care...
Psychosocial functioning in youths at high risk to develop major depressive disorderBoris Birmaher
Department of Child Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, Pittsburgh PA 15213, USA
J Am Acad Child Adolesc Psychiatry 43:839-46. 2004..To compare the psychosocial functioning of children and adolescents at high risk of major depressive disorder with youths with acute major depressive disorder and healthy controls...
Citalopram treatment of pediatric recurrent abdominal pain and comorbid internalizing disorders: an exploratory studyJohn V Campo
Department of Pyschiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
J Am Acad Child Adolesc Psychiatry 43:1234-42. 2004..To assess the potential efficacy, tolerability, and safety of citalopram in the treatment of functional pediatric recurrent abdominal pain and comorbid internalizing disorders...
Schedule for affective disorders and schizophrenia for school-age children (K-SADS-PL) for the assessment of preschool children--a preliminary psychometric studyBoris Birmaher
University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Psychiatr Res 43:680-6. 2009....
Pediatric depression: is there evidence to improve evidence-based treatments?David A Brent
University of Pittsburgh Medical Center, 200 Lothrop St, Pittsburgh, PA 15213 2582, USA
J Child Psychol Psychiatry 50:143-52. 2009..More effective treatments may emerge from being able to personalize interventions to the patient's cognitive, emotional, and developmental profile...
The prevalence and impact of large sudden improvements during adolescent therapy for depression: a comparison across cognitive-behavioral, family, and supportive therapyScott T Gaynor
Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
J Consult Clin Psychol 71:386-93. 2003..These findings suggest pretreatment and sudden within-treatment gains are important therapeutic events worthy of further investigation...
Clinical practice. Adolescent depressionDavid A Brent
Western Psychiatric Institute and Clinic, Division of Child and Adolescent Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, USA
N Engl J Med 347:667-71. 2002
Atypical symptoms of depression in a sample of depressed child and adolescent outpatientsD E Williamson
Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, USA
J Am Acad Child Adolesc Psychiatry 39:1253-9. 2000..To examine the presence of symptoms of atypical depression among children and adolescents with a major depressive disorder (MDD)...
Adolescent suicide and suicidal behaviorJeffrey A Bridge
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
J Child Psychol Psychiatry 47:372-94. 2006..On the basis of this review, clinical and public health approaches to the reduction in youth suicide and recommendations for further research will be discussed...
The risks and benefits of antidepressant treatment for youth depressionJeffrey A Bridge
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213-2592, USA
Ann Med 37:404-12. 2005....
Familial pathways to suicidal behavior--understanding and preventing suicide among adolescentsDavid A Brent
Services for Teens at Risk (STAR) Center at the University of Pittsburgh School of Medicine, Pittsburgh, USA
N Engl J Med 355:2719-21. 2006
Suicidality and its relationship to treatment outcome in depressed adolescentsRémy P Barbe
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2592, USA
Suicide Life Threat Behav 34:44-55. 2004..Hopelessness should be specifically targeted early in treatment. Suicidal depressed adolescents should not receive NST but a specific treatment like CBT...
Health risk behaviors in parentally bereaved youthMelissa Muñiz-Cohen
Child and Adolescent Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara St, Pittsburgh, PA 15213, USA
Arch Pediatr Adolesc Med 164:621-4. 2010..To investigate whether parentally bereaved offspring are more likely to engage in health risk behaviors than nonbereaved control offspring...
Family-focused treatment for adolescents with bipolar disorder: results of a 2-year randomized trialDavid J Miklowitz
Department of Psychology, University of Colorado, Boulder, CO 80309 0345, USA
Arch Gen Psychiatry 65:1053-61. 2008..Family interventions have been found to hasten episode recovery and delay recurrences among adults with bipolar disorder...
Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trialsJeffrey A Bridge
Department of Pediatrics and Columbus Children s Research Institute, The Ohio State University, Columbus, USA
JAMA 297:1683-96. 2007..The US Food and Drug Administration (FDA) has issued warnings that use of antidepressant medications poses a small but significantly increased risk of suicidal ideation/suicide attempt for children and adolescents...
Frequency of provider contact after FDA advisory on risk of pediatric suicidality with SSRIsElaine H Morrato
University of Colorado, Denver, CO 80262, USA
Am J Psychiatry 165:42-50. 2008..In this study, the authors compared trends in the frequency of provider contacts for patients with depression before and after the advisory was issued...
Physical and emotional health of mothers of youth with functional abdominal painJohn V Campo
Department of Psychiatry, Columbus Children s Hospital, The Ohio State University, Columbus 43205, USA
Arch Pediatr Adolesc Med 161:131-7. 2007..To determine if mothers of youth with functional abdominal pain (FAP) experience more anxiety, depressive, and somatic symptoms and disorders than mothers of unaffected children...
Comorbid anxiety in bipolar disorder: does it have an independent effect on suicidality?Atsuo Nakagawa
Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan
Bipolar Disord 10:530-8. 2008..This study examined the impact of comorbid Cluster B personality disorder and anxiety disorder on suicidality in bipolar disorder...
Depressed patients with co-occurring alcohol use disorders: a unique patient populationLeo Sher
Department of Psychiatry, Columbia University, and New York State Psychiatric Institute, New York, NY 10032, USA
J Clin Psychiatry 69:907-15. 2008..Few studies have assessed the impact of comorbid alcohol use disorders (AUDs) on clinical aspects of major depression. We compared depressed subjects with and without co-occurring AUDs with respect to demographic and clinical parameters...
Decline in treatment of pediatric depression after FDA advisory on risk of suicidality with SSRIsAnne M Libby
University of Colorado at Denver and Health Sciences Center, School of Medicine, Nighthorse Campbell Native Health Building, PO Box 6508, Campus Box F800, Aurora, CO 80045 0508, USA
Am J Psychiatry 164:884-91. 2007....
A comparison of the medical lethality of suicide attempts in bipolar and major depressive disordersGil Zalsman
Division of Neuroscience, Department of Psychiatry, Columbia University and New York State Psychiatric Institute, New York, NY 10032, USA
Bipolar Disord 8:558-65. 2006....
Family-focused treatment for adolescents with bipolar disorderDavid J Miklowitz
Department of Psychology, University of Colorado, Boulder, CO 80309 0345, USA
J Affect Disord 82:S113-28. 2004..The adult version of FFT has been shown to be effective in forestalling relapses in two randomized clinical trials involving bipolar adults...
Adolescents with depressionJeffrey A Bridge
JAMA 292:2578; author reply 2578-9. 2004
Posttraumatic stress disorder comorbid with major depression: factors mediating the association with suicidal behaviorMaria Oquendo
Department of Neuroscience, New York State Psychiatric Institute Columbia University, 1051 Riverside Dr, Unit 42, New York, NY 10032, USA
Am J Psychiatry 162:560-6. 2005....
The rewards of reducing riskDavid A Brent
Arch Pediatr Adolesc Med 158:824-5. 2004
Human 5-HT1A receptor C(-1019)G polymorphism and psychopathologyYung Yu Huang
Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
Int J Neuropsychopharmacol 7:441-51. 2004..The relationship does not appear to be explained by binding differences, although we cannot rule out altered receptor affinity and transduction...
Family history of suicidal behavior and mood disorders in probands with mood disordersJ John Mann
Department of Neuroscience, New York State Psychiatric Institute, 1051 Riverside Dr, Box 42, New York, NY 10032, USA
Am J Psychiatry 162:1672-9. 2005..This study examined the shared and distinctive factors associated with familial mood disorders and familial suicidal behavior...
Is the medication bottle for pediatric and adolescent depression half-full or half-empty?David A Brent
J Adolesc Health 37:431-3. 2005
Criterion validity of the Mood and Feelings Questionnaire for depressive episodes in clinic and non-clinic subjectsW Burleson Daviss
Western Psychiatric Institute and Clinic and the University of Pittsburgh, USA
J Child Psychol Psychiatry 47:927-34. 2006..The current study re-examines the criterion validity of child- and parent-versions of the Mood and Feelings Questionnaire (MFQ-C, MFQ-P) in a heterogeneous sample of children and adolescents from clinic and non-clinic sources...
Adolescent suicide and suicidal behavior: a time to assess and a time to treatDavid A Brent
Isr J Psychiatry Relat Sci 40:159-62. 2003
Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depressionGil Zalsman
Department of Neuroscience, New York State Psychiatric Institute, 1051 Riverside Dr, Box 42, New York, NY 10032, USA
Am J Psychiatry 163:1588-93. 2006..The authors examined the relationship of a triallelic 5-HTTLPR polymorphism to stressful life events, severity of major depression, and suicidality...
Cognitive behavioral therapy for depression in youthV Robin Weersing
Joint Doctoral Program in Clinical Psychology, San Diego State University University of California at San Diego, 6363 Alvarado Court, Suite 103, San Diego, CA 92120, USA
Child Adolesc Psychiatr Clin N Am 15:939-57, ix. 2006....
Association of serotonin 5-HT2A receptor binding and the T102C polymorphism in depressed and healthy Caucasian subjectsVadim D Khait
Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
Neuropsychopharmacology 30:166-72. 2005..The TT genotype appears associated with higher platelet 5-HT2A Bmax in the healthy population, but this genotypic effect appears absent in mood disorders and unrelated to psychopathology...
British warnings on SSRIs questionedDavid A Brent
J Am Acad Child Adolesc Psychiatry 43:379-80. 2004
Paroxetine and the FDADavid A Brent
J Am Acad Child Adolesc Psychiatry 43:127-8. 2004
Completed suicide in childhoodKanita Dervic
Department of Child and Adolescent Psychiatry University Hospital, Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
Psychiatr Clin North Am 31:271-91. 2008..Cognitive immaturity/misjudgment, age-related impulsivity, and availability of suicide methods play an important role. Psychologic autopsy studies that focus on suicides in this age group are needed...
[Depression in children and adolescents]Gil Zalsman
Neuroscience Division, Columbia University, USA
Harefuah 145:286-91, 318. 2006..Further research is needed to assess the efficacy and safety of these interventions and to better understand the etiological factors...
Screens and doors: the management of adolescent depression in primary careDavid A Brent
Arch Pediatr Adolesc Med 160:755-6. 2006
Effectiveness of cognitive-behavioral therapy for adolescent depression: a benchmarking investigationV Robin Weersing
Yale University School of Medicine, USA
Behav Ther 37:36-48. 2006..Results support further efforts to test the effectiveness of CBT in clinically representative community practice settings and samples...
Delinquent accounts: does delinquency account for suicidal behavior?David A Brent
J Adolesc Health 40:204-5. 2007
