Ellen Breen

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Impaired pulmonary defense against Pseudomonas aeruginosa in VEGF gene inactivated mouse lung
    Ellen C Breen
    Division of Physiology, Department of Medicine, University of California, San Diego, La Jolla, California 92093 0623, USA
    J Cell Physiol 228:371-9. 2013
  2. pmc Regional differences in expression of VEGF mRNA in rat gastrocnemius following 1 hr exercise or electrical stimulation
    Tom D Brutsaert
    Department of Physiology, School of Medicine, University of California, San Diego 92093 0623A, USA
    BMC Physiol 2:8. 2002
  3. doi request reprint Skeletal muscle capillarity during hypoxia: VEGF and its activation
    Ellen Breen
    Department of Medicine, University of California at San Diego, La Jolla, CA 92093 0623, USA
    High Alt Med Biol 9:158-66. 2008
  4. ncbi request reprint VEGF in biological control
    Ellen C Breen
    Department of Medicine, University of California at San Diego, San Diego, La Jolla, California 92093 0623, USA
    J Cell Biochem 102:1358-67. 2007
  5. ncbi request reprint Mechanical strain increases type I collagen expression in pulmonary fibroblasts in vitro
    E C Breen
    Division of Physiology, Department of Medicine, University of California, San Diego, La Jolla, California 92093 0623, USA
    J Appl Physiol 88:203-9. 2000
  6. ncbi request reprint Calcyclin (S100A6) regulates pulmonary fibroblast proliferation, morphology, and cytoskeletal organization in vitro
    Ellen C Breen
    Division of Physiology, Department of Medicine, University of California, San Diego, La Jolla, California, USA
    J Cell Biochem 88:848-54. 2003
  7. ncbi request reprint Lung-targeted VEGF inactivation leads to an emphysema phenotype in mice
    Kechun Tang
    Division of Physiology, Univ of California, San Diego, Dept of Medicine 0623A, 9500 Gilman Dr, La Jolla, CA 92093 0623, USA
    J Appl Physiol 97:1559-66; discussion 1549. 2004
  8. ncbi request reprint HIF and VEGF relationships in response to hypoxia and sciatic nerve stimulation in rat gastrocnemius
    Kechun Tang
    Division of Physiology 0623A, Department of Medicine, University of California at San Diego, La Jolla, CA 92093, USA
    Respir Physiol Neurobiol 144:71-80. 2004
  9. ncbi request reprint Capillary regression in vascular endothelial growth factor-deficient skeletal muscle
    Kechun Tang
    Division of Physiology, Department of Medicine, University of California, San Diego, La Jolla, California 92093 0623, USA
    Physiol Genomics 18:63-9. 2004
  10. ncbi request reprint Temporal thrombospondin-1 mRNA response in skeletal muscle exposed to acute and chronic exercise
    I Mark Olfert
    Division of Physiology, Department of Medicine, University of California San Diego, La Jolla, CA 92093 0623, USA
    Growth Factors 24:253-9. 2006

Detail Information

Publications14

  1. pmc Impaired pulmonary defense against Pseudomonas aeruginosa in VEGF gene inactivated mouse lung
    Ellen C Breen
    Division of Physiology, Department of Medicine, University of California, San Diego, La Jolla, California 92093 0623, USA
    J Cell Physiol 228:371-9. 2013
    ..TPA-induced DSPC secretion and apoptosis were elevated in VEGF-deficient type II cells. These results suggest a potential protective role for type II cell-expressed VEGF against bacterial initiated infection...
  2. pmc Regional differences in expression of VEGF mRNA in rat gastrocnemius following 1 hr exercise or electrical stimulation
    Tom D Brutsaert
    Department of Physiology, School of Medicine, University of California, San Diego 92093 0623A, USA
    BMC Physiol 2:8. 2002
    ..Functional regions were visualized on muscle cross sections that were matched in series to slides processed through in situ hybridization with a VEGF165 probe. A greater upregulation in oxidative regions was hypothesized...
  3. doi request reprint Skeletal muscle capillarity during hypoxia: VEGF and its activation
    Ellen Breen
    Department of Medicine, University of California at San Diego, La Jolla, CA 92093 0623, USA
    High Alt Med Biol 9:158-66. 2008
    ....
  4. ncbi request reprint VEGF in biological control
    Ellen C Breen
    Department of Medicine, University of California at San Diego, San Diego, La Jolla, California 92093 0623, USA
    J Cell Biochem 102:1358-67. 2007
    ..The following review will discuss the role of VEGF in physiological angiogenesis as well as its role in non-angiogenic processes that take place in adult organs...
  5. ncbi request reprint Mechanical strain increases type I collagen expression in pulmonary fibroblasts in vitro
    E C Breen
    Division of Physiology, Department of Medicine, University of California, San Diego, La Jolla, California 92093 0623, USA
    J Appl Physiol 88:203-9. 2000
    ..No difference was detected in strained fibroblasts cultured on fibronectin. These results suggest that fibroblasts respond to mechanical strain in vitro, and this response is signaled by cell-extracellular matrix interactions...
  6. ncbi request reprint Calcyclin (S100A6) regulates pulmonary fibroblast proliferation, morphology, and cytoskeletal organization in vitro
    Ellen C Breen
    Division of Physiology, Department of Medicine, University of California, San Diego, La Jolla, California, USA
    J Cell Biochem 88:848-54. 2003
    ..These observations suggest a role for calcyclin in modulating calcium dependent signaling events that regulate progression through the cell cycle. J. Cell. Biochem. 88: 848-854, 2003...
  7. ncbi request reprint Lung-targeted VEGF inactivation leads to an emphysema phenotype in mice
    Kechun Tang
    Division of Physiology, Univ of California, San Diego, Dept of Medicine 0623A, 9500 Gilman Dr, La Jolla, CA 92093 0623, USA
    J Appl Physiol 97:1559-66; discussion 1549. 2004
    ....
  8. ncbi request reprint HIF and VEGF relationships in response to hypoxia and sciatic nerve stimulation in rat gastrocnemius
    Kechun Tang
    Division of Physiology 0623A, Department of Medicine, University of California at San Diego, La Jolla, CA 92093, USA
    Respir Physiol Neurobiol 144:71-80. 2004
    ....
  9. ncbi request reprint Capillary regression in vascular endothelial growth factor-deficient skeletal muscle
    Kechun Tang
    Division of Physiology, Department of Medicine, University of California, San Diego, La Jolla, California 92093 0623, USA
    Physiol Genomics 18:63-9. 2004
    ..These data implicate VEGF as an essential survival factor for muscle capillarity and also demonstrate insufficient VEGF-dependent signaling leads to apoptosis in mouse skeletal muscle...
  10. ncbi request reprint Temporal thrombospondin-1 mRNA response in skeletal muscle exposed to acute and chronic exercise
    I Mark Olfert
    Division of Physiology, Department of Medicine, University of California San Diego, La Jolla, CA 92093 0623, USA
    Growth Factors 24:253-9. 2006
    ....
  11. doi request reprint Doxycycline treatment prevents alveolar destruction in VEGF-deficient mouse lung
    Harry B Rossiter
    Institute of Membrane and Systems Biology, University of Leeds, Leeds LS2 9JT, UK
    J Cell Biochem 104:525-35. 2008
    ..These results suggest that doxycycline treatment largely prevents the aberrant lung remodeling response observed in VEGF-deficient mouse lungs and is associated with changes in protease and anti-protease expression...
  12. ncbi request reprint Hu protein R-mediated posttranscriptional regulation of VEGF expression in rat gastrocnemius muscle
    Kechun Tang
    Division of Physiology, Department of Medicine, University of California, La Jolla 92093, USA
    Am J Physiol Heart Circ Physiol 283:H1497-504. 2002
    ..In skeletal muscle, this specific protein-RNA interaction may be an important posttranscriptional regulatory mechanism for increasing VEGF expression in response to hypoxia or acute ischemia...
  13. ncbi request reprint Muscle-targeted deletion of VEGF and exercise capacity in mice
    Peter D Wagner
    Division of Physiology, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, DEPT 0623A, La Jolla, CA 92093, USA
    Respir Physiol Neurobiol 151:159-66. 2006
    ..Because VEGF deletion is embryonically lethal, its study requires conditional and/or organ-targeted strategies. We inactivated the muscle VEGF gene in two ways:..
  14. ncbi request reprint High-resolution three-dimensional magnetic resonance imaging of mouse lung in situ
    Miriam Scadeng
    Department of Radiology, Center for Functional Magnetic Resonance Imaging, University of California, San Diego, La Jolla, California 92093, USA
    Invest Radiol 42:50-7. 2007
    ..This study establishes a method for high-resolution isotropic magnetic resonance (MR) imaging of mouse lungs using tracheal liquid-instillation to remove MR susceptibility artifacts...