Research Topics
Species | Barry BraunSummaryAffiliation: University of Massachusetts Country: USA Publications
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Publications
Independent and combined effects of exercise training and metformin on insulin sensitivity in individuals with prediabetesSteven K Malin
Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts, Amherst, Massachusetts, USA
Diabetes Care 35:131-6. 2012..We evaluated the effects of exercise training plus metformin on insulin sensitivity in men and women with prediabetes, compared with each treatment alone...
Effects of high altitude on substrate use and metabolic economy: cause and effect?Barry Braun
Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts Amherst, Amherst, MA 01003, USA
Med Sci Sports Exerc 40:1495-500. 2008..However, evidence from several experimental models is inconsistent with the idea that the increase in glucose use is causally related to greater metabolic economy...
Impact of metformin on peak aerobic capacityBarry Braun
Energy Metabolism Laboratory, Department of Kinesiology, School of Public Health and Health Sciences, 107 Totman Building, University of Massachusetts, Amherst, MA 01003, USA
Appl Physiol Nutr Metab 33:61-7. 2008..Whether this small but consistent effect is manifested in people with insulin resistance or diabetes who already have some degree of mitochondrial dysfunction remains to be determined...
The effect of carbohydrate availability following exercise on whole-body insulin actionKaila A Holtz
Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts, Amherst, MA 01003, USA
Appl Physiol Nutr Metab 33:946-56. 2008..82, p < 0.01). Following exercise, re-feeding expended energy, but not carbohydrate, increased fasting fat oxidation, and shifted insulin-mediated glucose disposal toward increased storage and away from oxidation...
Combining short-term metformin treatment and one bout of exercise does not increase insulin action in insulin-resistant individualsCarrie G Sharoff
Department of Kinesiology, University of Massachusetts Amherst, USA
Am J Physiol Endocrinol Metab 298:E815-23. 2010..These findings suggest that the combination of short-term metformin treatment and an acute bout of exercise does not enhance insulin sensitivity, and the addition of metformin may attenuate the well-documented effects of exercise alone...
Metformin's effect on exercise and postexercise substrate oxidationSteven K Malin
Dept of Kinesiology, University of Massachusetts Amherst, Amherst, MA, USA
Int J Sport Nutr Exerc Metab 20:63-71. 2010..68, p < .05). In healthy individuals, metformin has opposing actions on fat oxidation during and after exercise. Whether the same effects are evident in insulin-resistant individuals remains to be determined...
Effects of exercise on energy-regulating hormones and appetite in men and womenTodd A Hagobian
University of Massachusetts Amherst, Energy Metabolism Laboratory, Department of Kinesiology, 107 Totman Bldg, 30 Eastman Lane, Amherst, MA 01003, USA
Am J Physiol Regul Integr Comp Physiol 296:R233-42. 2009..In men, the response to exercise was abolished when energy balance was maintained. The data are consistent with the paradigm that mechanisms to maintain body fat are more effective in women...
Appetite regulation in response to sitting and energy imbalanceKirsten Granados
Department of Kinesiology, University of Massachusetts, Amherst, Amherst, MA 01003, USA
Appl Physiol Nutr Metab 37:323-33. 2012..Because a dramatic reduction in energy expenditure was not accompanied by reduced appetite, prolonged sitting may promote excess energy intake, leading to weight gain in both men and women...
Effects of short-term exercise and energy surplus on hormones related to regulation of energy balanceTodd A Hagobian
Department of Kinesiology, Energy Metabolism Laboratory, University of Massachusetts, Amherst, MA 01003, USA
Metabolism 57:393-8. 2008..These data suggest that the effect of short-term exercise on fasting leptin and insulin depends on energy balance but the ghrelin response may be partially mediated by effects of exercise independent of energy balance...
Effect of timing of energy and carbohydrate replacement on post-exercise insulin actionBrooke R Stephens
Energy Metabolism Laboratory, Department of Kinesiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003, USA
Appl Physiol Nutr Metab 32:1139-47. 2007..0%). A bout of exercise enhances insulin action even when expended energy and carbohydrate are replaced. Further, timing of energy and carbohydrate consumption subtly modulates the effectiveness of exercise to enhance insulin action...
Effects of insulin resistance on substrate utilization during exercise in overweight womenBarry Braun
Department of Exercise Science, University of Massachusetts, Amherst 01003, USA
J Appl Physiol 97:991-7. 2004..Insulin-resistant individuals with normoglycemia appear to have no defect in blood glucose uptake during exercise...
Effects of a single exercise bout on insulin sensitivity in black and white individualsRebecca E Hasson
University of Massachusetts Amherst, Department of Kinesiology, Amherst, Massachusetts 01003, USA
J Clin Endocrinol Metab 95:E219-23. 2010..Therefore, the purpose of this study was to compare metabolic responses to a single bout of exercise in blacks and age-, sex-, and body mass index-matched whites...
No effect of short-term testosterone manipulation on exercise substrate metabolism in menBarry Braun
Department of Exercise Science, 106 Totman Bldg, University of Massachusetts, Amherst, MA 01003, USA
J Appl Physiol 99:1930-7. 2005..20). In conclusion, unlike the effect of acute elevation in E to constrain carbohydrate use in women, acute changes in circulating T concentrations do not appear to alter substrate use during exercise in men...
Improved insulin action following short-term exercise training: role of energy and carbohydrate balanceSteven E Black
Dept. of Exercise Science, University of Massachusetts, Amherst, MA 01003, USA
J Appl Physiol 99:2285-93. 2005..These findings suggest that changes in short-term energy and/or carbohydrate balance play a key role in mediating the beneficial effects of exercise on whole body and hepatic insulin action...
Effects of 1 day of inactivity on insulin action in healthy men and women: interaction with energy intakeBrooke R Stephens
Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts Amherst, Amherst, MA 01003, USA
Metabolism 60:941-9. 2011..04). One day of sitting considerably reduced insulin action; this effect was minimized, but not prevented, when energy intake was reduced to match expenditure. Strategies to limit daily sitting may reduce metabolic disease risk...
Postexercise insulin action in African-American womenRebecca E Hasson
Department of Kinesiology, University of Massachusetts, Amherst, MA 01003, USA
J Natl Med Assoc 98:1832-9. 2006..CONCLUSIONS: These results indicate that overweight/obese, sedentary, insulin resistant African-American women had a significant improvement in insulin sensitivity from 75 minutes of brisk walking...
Does stride length influence metabolic cost and biomechanical risk factors for knee osteoarthritis in obese women?Elizabeth M Russell
Biomechanics and Energy Metabolism Laboratories, Department of Kinesiology, University of Massachusetts, 30 Eastman Lane, Amherst, MA 01003, USA
Clin Biomech (Bristol, Avon) 25:438-43. 2010....
Use of continuous glucose monitoring in normoglycemic, insulin-resistant womenRebecca E Hasson
Department of Kinesiology, University of Massachusetts, 106 Totman Building, Amherst, MA 01003, USA
Eur J Appl Physiol 108:1181-7. 2010..Although CGM provided more information regarding post-prandial glucose responses, these results suggest that CGM may not closely match venous glucose measurements in normoglycemic participants...
Psychological responses to acute exercise in sedentary black and white individualsRebecca E Hasson
Dept of Kinesiology, University of Massachusetts, Amherst, MA, USA
J Phys Act Health 8:978-87. 2011..To date, no study has examined racial differences in the psychological responses during and after exercise. The objective of this study was to compare psychological outcomes of single exercise bouts in blacks and whites...
Physical activity and hormonal regulation of appetite: sex differences and weight controlTodd A Hagobian
Department of Kinesiology, University of Massachusetts Amherst, 01003, USA
Exerc Sport Sci Rev 38:25-30. 2010..The evolving story may influence our thinking regarding the use of physical activity to manage body composition...
Interactions between energy surplus and short-term exercise on glucose and insulin responses in healthy people with induced, mild insulin insensitivityTodd A Hagobian
Energy Metabolism Laboratory, Department of Exercise Science, University of Massachusetts, Amherst, MA 01003, USA
Metabolism 55:402-8. 2006..A single exercise bout, opposed by a concurrent energy surplus, decreased the insulin response to a glucose challenge, but only partially restored the insulin AUC to baseline and had no impact on C-ISI or fasting insulin concentrations...
Regulation of exercise carbohydrate metabolism by estrogen and progesterone in womenCarrie Sharoff
Department of Exercise Science, University of Massachusetts, Amherst, MA 01003, USA
Am J Physiol Endocrinol Metab 283:E1046-55. 2002..Progesterone increases EMGU but not glucose R(d). The opposing actions of E(2) and P(4) on EMGU may be mediated by their impact on FFA availability or vice versa...
Impact of nutrient intake timing on the metabolic response to exerciseBrooke R Stephens
Department of Kinesiology, Energy Metabolism Laboratory, School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts 01003, USA
Nutr Rev 66:473-6. 2008..Altered nutrient intake timing relative to exercise can modulate the metabolic response, which is relevant for individuals seeking to use exercise to enhance health...
Effect of high cardiorespiratory fitness and high body fat on insulin resistanceLaura S Gerson
Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts, Amherst, MA 01003, USA
Med Sci Sports Exerc 38:1709-15. 2006....
Physical activity and gestational diabetes mellitus among Hispanic womenLisa Chasan-Taber
Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts 01003 9304, USA
J Womens Health (Larchmt) 17:999-1008. 2008..There are few such studies in Hispanic women, a group at increased risk for GDM...
Effects of a single bout of exercise on resting heart rate variabilityDavid M Pober
Department of Exercise Science and Department of Mathematics and Statistics, University of Massachusetts, Amherst, MA, USA
Med Sci Sports Exerc 36:1140-8. 2004..These results may provide further evidence of the cardioprotective effects of a single bout of submaximal exercise...
Feasibility and efficacy of a physical activity intervention among pregnant women: the behaviors affecting baby and you (B.A.B.Y.) studyLisa Chasan-Taber
Dept of Public Health, University of Massachusetts, Amherst, MA, USA
J Phys Act Health 8:S228-38. 2011..We evaluated the feasibility and preliminary efficacy of an exercise intervention among a diverse sample of pregnant women...
Influence of gender, estrogen and exercise on anterior knee laxityChristine D Pollard
Department of Exercise Science, University of Massachusetts, Amherst, MA, USA
Clin Biomech (Bristol, Avon) 21:1060-6. 2006..The purpose of this study was to investigate the collective effects of gender, estrogen and exercise on knee laxity...
Critical importance of controlling energy status to understand the effects of "exercise" on metabolismBarry Braun
Department of Kinesiology, University of Massachusetts, Amherst, MA, USA
Exerc Sport Sci Rev 36:2-4. 2008
The roles of estrogen and progesterone in regulating carbohydrate and fat utilization at rest and during exerciseBarry Braun
Department of Exercise Science, University of Massachusetts, Amherst 01003, USA
J Womens Health Gend Based Med 11:225-37. 2002....
Endocrine responses to acute and chronic high-altitude exposure (4,300 meters): modulating effects of caloric restrictionKimberly E Barnholt
Clinical Studies Unit, VA Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304, USA
Am J Physiol Endocrinol Metab 290:E1078-88. 2006..Such suppression results in the preservation of energy stores but may sacrifice the facilitation of oxygen delivery and the use of oxygen-efficient fuels...
Three weeks of caloric restriction alters protein metabolism in normal-weight, young menAnne L Friedlander
Geriatric Research Education and Clinical Center and Research and Medical Services, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA
Am J Physiol Endocrinol Metab 289:E446-55. 2005..However, despite negative nitrogen balance and loss of lean mass, whole body exercise performance was well maintained in response to CR...
Five weeks of insulin-like growth factor-I treatment does not alter glucose kinetics or insulin sensitivity during a hyperglycemic clamp in older womenBarry Braun
Geriatric Research Education and Clinical Center and Medical Service, VA Palo Alto Health Care System, CA, USA
Metabolism 52:1182-90. 2003..The data suggest that 5 weeks of low-dose rhIGF-I treatment has no material influence on whole-body insulin sensitivity in normoglycemic postmenopausal women...
Continuous glucose monitoring counseling improves physical activity behaviors of individuals with type 2 diabetes: A randomized clinical trialNancy A Allen
Yale University School of Nursing, 100 Church Street South, P O Box 9740, New Haven, CT 06536 0740, United States
Diabetes Res Clin Pract 80:371-9. 2008..This pilot study tested the effects of a counseling intervention using continuous glucose monitoring system (CGMS) feedback on PA self-efficacy, PA levels, and physiological variables...
Cytokine responses at high altitude: effects of exercise and antioxidants at 4300 mTodd A Hagobian
Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304-1290, USA
Med Sci Sports Exerc 38:276-85. 2006....
Influence of alpha-adrenergic blockade on the catecholamine response to exercise at 4,300 metersRobert S Mazzeo
Department of Kinesiology and Applied Physiology, University of Colorado, Boulder 80309, USA
Metabolism 52:1471-7. 2003....
