Barry Braun

Summary

Affiliation: University of Massachusetts
Country: USA

Publications

  1. pmc Independent and combined effects of exercise training and metformin on insulin sensitivity in individuals with prediabetes
    Steven K Malin
    Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts, Amherst, Massachusetts, USA
    Diabetes Care 35:131-6. 2012
  2. doi request reprint Effects of high altitude on substrate use and metabolic economy: cause and effect?
    Barry Braun
    Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts Amherst, Amherst, MA 01003, USA
    Med Sci Sports Exerc 40:1495-500. 2008
  3. doi request reprint Impact of metformin on peak aerobic capacity
    Barry Braun
    Energy Metabolism Laboratory, Department of Kinesiology, School of Public Health and Health Sciences, 107 Totman Building, University of Massachusetts, Amherst, MA 01003, USA
    Appl Physiol Nutr Metab 33:61-7. 2008
  4. doi request reprint The effect of carbohydrate availability following exercise on whole-body insulin action
    Kaila A Holtz
    Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts, Amherst, MA 01003, USA
    Appl Physiol Nutr Metab 33:946-56. 2008
  5. pmc Combining short-term metformin treatment and one bout of exercise does not increase insulin action in insulin-resistant individuals
    Carrie G Sharoff
    Department of Kinesiology, University of Massachusetts Amherst, USA
    Am J Physiol Endocrinol Metab 298:E815-23. 2010
  6. pmc Effects of exercise on energy-regulating hormones and appetite in men and women
    Todd A Hagobian
    University of Massachusetts Amherst, Energy Metabolism Laboratory, Department of Kinesiology, 107 Totman Bldg, 30 Eastman Lane, Amherst, MA 01003, USA
    Am J Physiol Regul Integr Comp Physiol 296:R233-42. 2009
  7. ncbi request reprint Metformin's effect on exercise and postexercise substrate oxidation
    Steven K Malin
    Dept of Kinesiology, University of Massachusetts Amherst, Amherst, MA, USA
    Int J Sport Nutr Exerc Metab 20:63-71. 2010
  8. pmc Mild fasting hyperglycemia shifts fuel reliance toward fat during exercise in adults with impaired glucose tolerance
    Steven K Malin
    Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts, Amherst, MA 01003, USA
    J Appl Physiol (1985) 115:78-83. 2013
  9. doi request reprint Appetite regulation in response to sitting and energy imbalance
    Kirsten Granados
    Department of Kinesiology, University of Massachusetts, Amherst, Amherst, MA 01003, USA
    Appl Physiol Nutr Metab 37:323-33. 2012
  10. doi request reprint Effects of short-term exercise and energy surplus on hormones related to regulation of energy balance
    Todd A Hagobian
    Department of Kinesiology, Energy Metabolism Laboratory, University of Massachusetts, Amherst, MA 01003, USA
    Metabolism 57:393-8. 2008

Collaborators

Detail Information

Publications41

  1. pmc Independent and combined effects of exercise training and metformin on insulin sensitivity in individuals with prediabetes
    Steven K Malin
    Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts, Amherst, Massachusetts, USA
    Diabetes Care 35:131-6. 2012
    ..We evaluated the effects of exercise training plus metformin on insulin sensitivity in men and women with prediabetes, compared with each treatment alone...
  2. doi request reprint Effects of high altitude on substrate use and metabolic economy: cause and effect?
    Barry Braun
    Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts Amherst, Amherst, MA 01003, USA
    Med Sci Sports Exerc 40:1495-500. 2008
    ..However, evidence from several experimental models is inconsistent with the idea that the increase in glucose use is causally related to greater metabolic economy...
  3. doi request reprint Impact of metformin on peak aerobic capacity
    Barry Braun
    Energy Metabolism Laboratory, Department of Kinesiology, School of Public Health and Health Sciences, 107 Totman Building, University of Massachusetts, Amherst, MA 01003, USA
    Appl Physiol Nutr Metab 33:61-7. 2008
    ..Whether this small but consistent effect is manifested in people with insulin resistance or diabetes who already have some degree of mitochondrial dysfunction remains to be determined...
  4. doi request reprint The effect of carbohydrate availability following exercise on whole-body insulin action
    Kaila A Holtz
    Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts, Amherst, MA 01003, USA
    Appl Physiol Nutr Metab 33:946-56. 2008
    ..82, p < 0.01). Following exercise, re-feeding expended energy, but not carbohydrate, increased fasting fat oxidation, and shifted insulin-mediated glucose disposal toward increased storage and away from oxidation...
  5. pmc Combining short-term metformin treatment and one bout of exercise does not increase insulin action in insulin-resistant individuals
    Carrie G Sharoff
    Department of Kinesiology, University of Massachusetts Amherst, USA
    Am J Physiol Endocrinol Metab 298:E815-23. 2010
    ..These findings suggest that the combination of short-term metformin treatment and an acute bout of exercise does not enhance insulin sensitivity, and the addition of metformin may attenuate the well-documented effects of exercise alone...
  6. pmc Effects of exercise on energy-regulating hormones and appetite in men and women
    Todd A Hagobian
    University of Massachusetts Amherst, Energy Metabolism Laboratory, Department of Kinesiology, 107 Totman Bldg, 30 Eastman Lane, Amherst, MA 01003, USA
    Am J Physiol Regul Integr Comp Physiol 296:R233-42. 2009
    ..In men, the response to exercise was abolished when energy balance was maintained. The data are consistent with the paradigm that mechanisms to maintain body fat are more effective in women...
  7. ncbi request reprint Metformin's effect on exercise and postexercise substrate oxidation
    Steven K Malin
    Dept of Kinesiology, University of Massachusetts Amherst, Amherst, MA, USA
    Int J Sport Nutr Exerc Metab 20:63-71. 2010
    ..68, p < .05). In healthy individuals, metformin has opposing actions on fat oxidation during and after exercise. Whether the same effects are evident in insulin-resistant individuals remains to be determined...
  8. pmc Mild fasting hyperglycemia shifts fuel reliance toward fat during exercise in adults with impaired glucose tolerance
    Steven K Malin
    Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts, Amherst, MA 01003, USA
    J Appl Physiol (1985) 115:78-83. 2013
    ..Whether these differences in substrate use contribute to, or are the result of, movement along the continuum from prediabetes to type 2 diabetes awaits further work. ..
  9. doi request reprint Appetite regulation in response to sitting and energy imbalance
    Kirsten Granados
    Department of Kinesiology, University of Massachusetts, Amherst, Amherst, MA 01003, USA
    Appl Physiol Nutr Metab 37:323-33. 2012
    ..Because a dramatic reduction in energy expenditure was not accompanied by reduced appetite, prolonged sitting may promote excess energy intake, leading to weight gain in both men and women...
  10. doi request reprint Effects of short-term exercise and energy surplus on hormones related to regulation of energy balance
    Todd A Hagobian
    Department of Kinesiology, Energy Metabolism Laboratory, University of Massachusetts, Amherst, MA 01003, USA
    Metabolism 57:393-8. 2008
    ..These data suggest that the effect of short-term exercise on fasting leptin and insulin depends on energy balance but the ghrelin response may be partially mediated by effects of exercise independent of energy balance...
  11. ncbi request reprint Effect of timing of energy and carbohydrate replacement on post-exercise insulin action
    Brooke R Stephens
    Energy Metabolism Laboratory, Department of Kinesiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003, USA
    Appl Physiol Nutr Metab 32:1139-47. 2007
    ..0%). A bout of exercise enhances insulin action even when expended energy and carbohydrate are replaced. Further, timing of energy and carbohydrate consumption subtly modulates the effectiveness of exercise to enhance insulin action...
  12. ncbi request reprint Effects of insulin resistance on substrate utilization during exercise in overweight women
    Barry Braun
    Department of Exercise Science, University of Massachusetts, Amherst 01003, USA
    J Appl Physiol (1985) 97:991-7. 2004
    ..Insulin-resistant individuals with normoglycemia appear to have no defect in blood glucose uptake during exercise...
  13. ncbi request reprint No effect of short-term testosterone manipulation on exercise substrate metabolism in men
    Barry Braun
    Department of Exercise Science, 106 Totman Bldg, University of Massachusetts, Amherst, MA 01003, USA
    J Appl Physiol (1985) 99:1930-7. 2005
    ..20). In conclusion, unlike the effect of acute elevation in E to constrain carbohydrate use in women, acute changes in circulating T concentrations do not appear to alter substrate use during exercise in men...
  14. doi request reprint Effects of a single exercise bout on insulin sensitivity in black and white individuals
    Rebecca E Hasson
    University of Massachusetts Amherst, Department of Kinesiology, Amherst, Massachusetts 01003, USA
    J Clin Endocrinol Metab 95:E219-23. 2010
    ..Therefore, the purpose of this study was to compare metabolic responses to a single bout of exercise in blacks and age-, sex-, and body mass index-matched whites...
  15. pmc Metformin modifies the exercise training effects on risk factors for cardiovascular disease in impaired glucose tolerant adults
    Steven K Malin
    Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts, Amherst, Massachusetts, USA
    Obesity (Silver Spring) 21:93-100. 2013
    ..Impaired glucose tolerant (IGT) adults are at elevated risk for cardiovascular disease (CVD). Exercise or metformin reduce CVD risk, but the efficacy of combining treatments is unclear...
  16. ncbi request reprint Improved insulin action following short-term exercise training: role of energy and carbohydrate balance
    Steven E Black
    Dept of Exercise Science, University of Massachusetts, Amherst, MA 01003, USA
    J Appl Physiol 99:2285-93. 2005
    ..These findings suggest that changes in short-term energy and/or carbohydrate balance play a key role in mediating the beneficial effects of exercise on whole body and hepatic insulin action...
  17. doi request reprint Effects of 1 day of inactivity on insulin action in healthy men and women: interaction with energy intake
    Brooke R Stephens
    Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts Amherst, Amherst, MA 01003, USA
    Metabolism 60:941-9. 2011
    ..04). One day of sitting considerably reduced insulin action; this effect was minimized, but not prevented, when energy intake was reduced to match expenditure. Strategies to limit daily sitting may reduce metabolic disease risk...
  18. pmc Postexercise insulin action in African-American women
    Rebecca E Hasson
    Department of Kinesiology, University of Massachusetts, Amherst, MA 01003, USA
    J Natl Med Assoc 98:1832-9. 2006
    ..The purpose of this experiment was to evaluate the impact of a single bout of exercise on insulin resistance in African-American women...
  19. ncbi request reprint Psychological responses to acute exercise in sedentary black and white individuals
    Rebecca E Hasson
    Dept of Kinesiology, University of Massachusetts, Amherst, MA, USA
    J Phys Act Health 8:978-87. 2011
    ..To date, no study has examined racial differences in the psychological responses during and after exercise. The objective of this study was to compare psychological outcomes of single exercise bouts in blacks and whites...
  20. doi request reprint Use of continuous glucose monitoring in normoglycemic, insulin-resistant women
    Rebecca E Hasson
    Department of Kinesiology, University of Massachusetts, 106 Totman Building, Amherst, MA 01003, USA
    Eur J Appl Physiol 108:1181-7. 2010
    ..Although CGM provided more information regarding post-prandial glucose responses, these results suggest that CGM may not closely match venous glucose measurements in normoglycemic participants...
  21. doi request reprint Does stride length influence metabolic cost and biomechanical risk factors for knee osteoarthritis in obese women?
    Elizabeth M Russell
    Biomechanics and Energy Metabolism Laboratories, Department of Kinesiology, University of Massachusetts, 30 Eastman Lane, Amherst, MA 01003, USA
    Clin Biomech (Bristol, Avon) 25:438-43. 2010
    ....
  22. doi request reprint Physical activity and hormonal regulation of appetite: sex differences and weight control
    Todd A Hagobian
    Department of Kinesiology, University of Massachusetts Amherst, 01003, USA
    Exerc Sport Sci Rev 38:25-30. 2010
    ..The evolving story may influence our thinking regarding the use of physical activity to manage body composition...
  23. ncbi request reprint Interactions between energy surplus and short-term exercise on glucose and insulin responses in healthy people with induced, mild insulin insensitivity
    Todd A Hagobian
    Energy Metabolism Laboratory, Department of Exercise Science, University of Massachusetts, Amherst, MA 01003, USA
    Metabolism 55:402-8. 2006
    ..A single exercise bout, opposed by a concurrent energy surplus, decreased the insulin response to a glucose challenge, but only partially restored the insulin AUC to baseline and had no impact on C-ISI or fasting insulin concentrations...
  24. doi request reprint Impact of nutrient intake timing on the metabolic response to exercise
    Brooke R Stephens
    Department of Kinesiology, Energy Metabolism Laboratory, School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts 01003, USA
    Nutr Rev 66:473-6. 2008
    ..Altered nutrient intake timing relative to exercise can modulate the metabolic response, which is relevant for individuals seeking to use exercise to enhance health...
  25. ncbi request reprint Regulation of exercise carbohydrate metabolism by estrogen and progesterone in women
    Tara M D'Eon
    Department of Exercise Science, University of Massachusetts, Amherst, MA 01003, USA
    Am J Physiol Endocrinol Metab 283:E1046-55. 2002
    ..Progesterone increases EMGU but not glucose R(d). The opposing actions of E(2) and P(4) on EMGU may be mediated by their impact on FFA availability or vice versa...
  26. ncbi request reprint Effect of high cardiorespiratory fitness and high body fat on insulin resistance
    Laura S Gerson
    Energy Metabolism Laboratory, Department of Kinesiology, University of Massachusetts, Amherst, MA 01003, USA
    Med Sci Sports Exerc 38:1709-15. 2006
    ..This effect is likely attributable to the inverse relationship between high CRF and insulin resistance. In this study, the independent effects of high body fat and high CRF on insulin resistance were assessed...
  27. doi request reprint Physical activity and gestational diabetes mellitus among Hispanic women
    Lisa Chasan-Taber
    Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts 01003 9304, USA
    J Womens Health (Larchmt) 17:999-1008. 2008
    ..There are few such studies in Hispanic women, a group at increased risk for GDM...
  28. doi request reprint Prenatal depressive symptoms and abnormalities of glucose tolerance during pregnancy among Hispanic women
    Karen A Ertel
    Division of Biostatistics and Epidemiology, Department of Public Health, School of Public Health and Health Sciences, University of Massachusetts, 423 Arnold House, 715 North Pleasant Street, Amherst, MA, 01003 9304, USA
    Arch Womens Ment Health 17:65-72. 2014
    ..Due to the small number of cases of IGT, our ability to evaluate the association between depression and IGT risk was constrained. ..
  29. ncbi request reprint Influence of gender, estrogen and exercise on anterior knee laxity
    Christine D Pollard
    Department of Exercise Science, University of Massachusetts, Amherst, MA, USA
    Clin Biomech (Bristol, Avon) 21:1060-6. 2006
    ..The purpose of this study was to investigate the collective effects of gender, estrogen and exercise on knee laxity...
  30. ncbi request reprint Feasibility and efficacy of a physical activity intervention among pregnant women: the behaviors affecting baby and you (B.A.B.Y.) study
    Lisa Chasan-Taber
    Dept of Public Health, University of Massachusetts, Amherst, MA, USA
    J Phys Act Health 8:S228-38. 2011
    ..We evaluated the feasibility and preliminary efficacy of an exercise intervention among a diverse sample of pregnant women...
  31. ncbi request reprint Effects of a single bout of exercise on resting heart rate variability
    David M Pober
    Department of Exercise Science and Department of Mathematics and Statistics, University of Massachusetts, Amherst, MA, USA
    Med Sci Sports Exerc 36:1140-8. 2004
    ....
  32. ncbi request reprint Critical importance of controlling energy status to understand the effects of "exercise" on metabolism
    Barry Braun
    Department of Kinesiology, University of Massachusetts, Amherst, MA, USA
    Exerc Sport Sci Rev 36:2-4. 2008
  33. doi request reprint Economy and rate of carbohydrate oxidation during running with rearfoot and forefoot strike patterns
    Allison H Gruber
    Department of Kinesiology, University of Massachusetts, Amherst, Massachusetts, USA
    J Appl Physiol (1985) 115:194-201. 2013
    ..05), but %CHO was not different (P > 0.05). The results suggest that the FF pattern is not more economical than the RF pattern. ..
  34. doi request reprint Effect of metformin on substrate utilization after exercise training in adults with impaired glucose tolerance
    Steven K Malin
    Energy Metabolism Laboratory, Department of Kinesiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003, USA
    Appl Physiol Nutr Metab 38:427-30. 2013
    ..Blood glucose use was unchanged. Training-induced enhancement of insulin sensitivity (clamp) correlated with higher peak oxygen uptake (r = 0.70; p < 0.05), but was independent of glucose kinetic and substrate metabolism...
  35. ncbi request reprint The roles of estrogen and progesterone in regulating carbohydrate and fat utilization at rest and during exercise
    Tara D'Eon
    Department of Exercise Science, University of Massachusetts, Amherst 01003, USA
    J Womens Health Gend Based Med 11:225-37. 2002
    ..Circulating levels of estrogen and progesterone are likely to play an important role in explaining this gender difference in exercise substrate utilization...
  36. ncbi request reprint Three weeks of caloric restriction alters protein metabolism in normal-weight, young men
    Anne L Friedlander
    Geriatric Research Education and Clinical Center and Research and Medical Services, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA
    Am J Physiol Endocrinol Metab 289:E446-55. 2005
    ..However, despite negative nitrogen balance and loss of lean mass, whole body exercise performance was well maintained in response to CR...
  37. pmc Continuous glucose monitoring counseling improves physical activity behaviors of individuals with type 2 diabetes: A randomized clinical trial
    Nancy A Allen
    Yale University School of Nursing, 100 Church Street South, P O Box 9740, New Haven, CT 06536 0740, United States
    Diabetes Res Clin Pract 80:371-9. 2008
    ..This pilot study tested the effects of a counseling intervention using continuous glucose monitoring system (CGMS) feedback on PA self-efficacy, PA levels, and physiological variables...
  38. ncbi request reprint Five weeks of insulin-like growth factor-I treatment does not alter glucose kinetics or insulin sensitivity during a hyperglycemic clamp in older women
    Barry Braun
    Geriatric Research Education and Clinical Center and Medical Service, VA Palo Alto Health Care System, CA, USA
    Metabolism 52:1182-90. 2003
    ..The data suggest that 5 weeks of low-dose rhIGF-I treatment has no material influence on whole-body insulin sensitivity in normoglycemic postmenopausal women...
  39. ncbi request reprint Endocrine responses to acute and chronic high-altitude exposure (4,300 meters): modulating effects of caloric restriction
    Kimberly E Barnholt
    Clinical Studies Unit, VA Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304, USA
    Am J Physiol Endocrinol Metab 290:E1078-88. 2006
    ..Such suppression results in the preservation of energy stores but may sacrifice the facilitation of oxygen delivery and the use of oxygen-efficient fuels...
  40. ncbi request reprint Influence of alpha-adrenergic blockade on the catecholamine response to exercise at 4,300 meters
    Robert S Mazzeo
    Department of Kinesiology and Applied Physiology, University of Colorado, Boulder 80309, USA
    Metabolism 52:1471-7. 2003
    ....
  41. ncbi request reprint Cytokine responses at high altitude: effects of exercise and antioxidants at 4300 m
    Todd A Hagobian
    Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304 1290, USA
    Med Sci Sports Exerc 38:276-85. 2006
    ....