AARON BRAULTSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Publications
Differential virulence of West Nile strains for American crowsAaron C Brault
Centers for Disease Control and Prevention, Fort Collins, Colorado, USA
Emerg Infect Dis 10:2161-8. 2004..These results suggest that genetic alterations in NY99 WNV are responsible for the crow-virulent phenotype and that increased replication of this strain in crows could spread WNV in North America...
A single positively selected West Nile viral mutation confers increased virogenesis in American crowsAaron C Brault
Center for Vector Borne Diseases and Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, California 95616, USA
Nat Genet 39:1162-6. 2007..These phenotypic and evolutionary results provide compelling evidence for the positive selection of a mutation encoding increased viremia potential and virulence in the AMCR sentinel bird species...- Changing patterns of West Nile virus transmission: altered vector competence and host susceptibilityAaron C Brault
Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Vet Res 40:43. 2009.... 
Overwintering of West Nile virus in Southern CaliforniaWilliam K Reisen
Department of Pathology, Microbiology and Immunology, Center for Vectorborne Diseases, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Med Entomol 43:344-55. 2006..Continued transmission andvertical transmission by Culex p. quinquefasciatus Say seem likely candidates for further study...- Limited interdecadal variation in mosquito (Diptera: Culicidae) and avian host competence for Western equine encephalomyelitis virus (Togaviridae: Alphavirus)William K Reisen
Arbovirus Research Unit, Center for Vectorborne Diseases, School of Veterinary Medicine, University of California, Davis, California 95616, USA
Am J Trop Med Hyg 78:681-6. 2008..tarsalis. Although temporal and spatial genetic changes have been documented, these seem to present limited phenotypic change in host competence and cannot explain the absence of equine and human cases... - Rapid West Nile virus antigen detectionNicholas A Panella
Arbovirus Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA
Emerg Infect Dis 11:1633-5. 2005..The VecTest detected WNV more frequently than the plaque assay and was comparable to a TaqMan reverse transcription-polymerase chain reaction... - West Nile virus detection in nonvascular feathers from avian carcassesNicole M Nemeth
Division of Vector Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA
J Vet Diagn Invest 21:616-22. 2009.... - Variation in virulence of West Nile virus strains for house sparrows (Passer domesticus)Stanley A Langevin
Center for Vector borne Diseases, Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis 95616, USA
Am J Trop Med Hyg 72:99-102. 2005..This study suggests that natural mortality in house sparrows due to Old World strains of WNV may be occurring where the KEN strain occurs... - Avian virulence and thermostable replication of the North American strain of West Nile virusRichard M Kinney
Division of Vector Borne Infectious Diseases, National Center for Zoonotic, Vector Borne and Enteric Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, PO Box 2087, Fort Collins, CO 80522, USA
J Gen Virol 87:3611-22. 2006..These results indicated that the ability of WNV NY99 to replicate at the high temperatures measured in infected AMCRs could be an important factor leading to the increased avian virulence and emergence of this strain of WNV... - Comparative pathogenesis of epidemic and enzootic Chikungunya viruses in a pregnant Rhesus macaque modelChing I Chen
Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, California 95616, USA
Am J Trop Med Hyg 83:1249-58. 2010..Our study establishes a non-human primate model for evaluating vaccines and antiviral therapies and indicates that Rhesus macaques could serve as a competent enzootic reservoir... - Comparative thermostability of West Nile, St. Louis encephalitis, and western equine encephalomyelitis viruses during heat inactivation for serologic diagnosticsYing Fang
Center for Vectorborne Diseases and Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, California 95616, USA
Am J Trop Med Hyg 80:862-3. 2009..Occasional presence of live virus within sera could lead to false negatives using standard plaque reduction neutralization test protocols... - Avian hosts for West Nile virus in St. Tammany Parish, Louisiana, 2002Nicholas Komar
Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA
Am J Trop Med Hyg 73:1031-7. 2005..The blue jay population was reduced by an estimated 47%. A variety of passerine bird species combined to play an important role as amplifying hosts in the WNV transmission cycle... - Virulence variation among isolates of western equine encephalitis virus in an outbred mouse modelChristopher H Logue
Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
J Gen Virol 90:1848-58. 2009.... - Phylogenetic analysis of North American West Nile virus isolates, 2001-2004: evidence for the emergence of a dominant genotypeC Todd Davis
Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, and Sealy Center for Vaccine Development, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77550-0609, USA
Virology 342:252-65. 2005..The implications of these findings are discussed as they relate to transmission and spread of the virus in the Western Hemisphere... - West Nile virus infection in a green-winged macaw (Ara chloropterus)Jonathan Stockman
William R Pritchard Veterinary Medical Teaching Hospital VMTH, School of Veterinary Medicine, University of California, Davis, Davis 95616, USA
Avian Dis 54:164-9. 2010..WNV was successfully isolated from brain, pancreas, spleen, and liver. To our knowledge, this is the first report characterizing WNV disease in a green-winged macaw and one of few reports of this disease in a psittacine bird... - Acute encephalitis, polyarthritis, and myocarditis associated with West Nile virus infection in a dogAllison B Cannon
Department of Medicine and Epidemiology, University of California, Davis 95616, USA
J Vet Intern Med 20:1219-23. 2006 - West Nile virus in North America: perspectives on epidemiology and interventionWilliam Reisen
Center for Vector Borne Diseases and Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Pest Manag Sci 63:641-6. 2007..Intervention has included mass vaccination of equines, and proactive and reactive mosquito control. Proactive mosquito control in areas with established infrastructure has been successful in reducing case incidence... - Venezuelan equine encephalitis virus in the guinea pig model: evidence for epizootic virulence determinants outside the E2 envelope glycoprotein geneIvorlyne P Greene
Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555-0609, USA
Am J Trop Med Hyg 72:330-8. 2005..However, early replication in lymphoid tissues appeared to be primarily envelope dependent... - Stone Lakes virus (family Togaviridae, genus Alphavirus), a variant of Fort Morgan virus isolated from swallow bugs (Hemiptera: Cimicidae) west of the Continental DivideAaron C Brault
Center for Vector borne Diseases, Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Old Davis Road, Davis, CA 95616, USA
J Med Entomol 46:1203-9. 2009.... - Genetic relationships among Mayaro and Una viruses suggest distinct patterns of transmissionAnn M Powers
Centers for Disease Control and Prevention, Division of Vector Borne Infectious Diseases, Fort Collins, Colorado 80522, USA
Am J Trop Med Hyg 75:461-9. 2006..These analyses provide possible explanations for the natural ecology and transmission of MAYV and UNAV...
Research Grants
- West Nile Virus Genotypic Affect on Host CompetenceAARON BRAULT; Fiscal Year: 2006..abstract_text> ..
- West Nile Viral Determinants of Avian PathogenesisAARON BRAULT; Fiscal Year: 2007..In addition, fundamental knowledge of viral replication and pathogenesis will provide insight for the development of vaccine and antiviral strategies. ..