Roberta Brambilla

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. doi request reprint Transgenic inhibition of astroglial NF-kappa B leads to increased axonal sparing and sprouting following spinal cord injury
    Roberta Brambilla
    Department of Neurological Surgery, University of Miami, Florida 33136, USA
    J Neurochem 110:765-78. 2009
  2. pmc Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination
    Roberta Brambilla
    The Miami Project to Cure Paralysis, Miller School of Medicine, University of Miami 1095 NW 14th Terrace, Miami, FL 33136, USA
    Brain 134:2736-54. 2011
  3. doi request reprint Transgenic inhibition of astroglial NF-kappa B improves functional outcome in experimental autoimmune encephalomyelitis by suppressing chronic central nervous system inflammation
    Roberta Brambilla
    The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, 1095 Northwest 14th Terrace, Miami, FL 33136, USA
    J Immunol 182:2628-40. 2009
  4. pmc Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury
    Roberta Brambilla
    The Miami Project to Cure Paralysis, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    J Exp Med 202:145-56. 2005
  5. pmc Transgenic inhibition of astroglial NF-κB protects from optic nerve damage and retinal ganglion cell loss in experimental optic neuritis
    Roberta Brambilla
    Department of Neurological Surgery, The Miami Project to Cure Paralysis, Miller School of Medicine, University of Miami, FL 33136, USA
    J Neuroinflammation 9:213. 2012
  6. pmc Inactivation of astroglial NF-kappa B promotes survival of retinal neurons following ischemic injury
    Galina Dvoriantchikova
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA
    Eur J Neurosci 30:175-85. 2009
  7. doi request reprint Glial NF-κB inhibition alters neuropeptide expression after sciatic nerve injury in mice
    Yan Ping Zhang
    Department of Anesthesiology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Brain Res 1385:38-46. 2011
  8. ncbi request reprint Astroglial nuclear factor-kappaB regulates learning and memory and synaptic plasticity in female mice
    Valerie Bracchi-Ricard
    The Miami Project to Cure Paralysis, Department of Neurological Surgery, University of Miami School of Medicine, Miami, Florida 33136, USA
    J Neurochem 104:611-23. 2008
  9. pmc NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation
    Wen Hui Hu
    The Miami Project to Cure Paralysis, Department of Neurological Surgery, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    J Biol Chem 280:29233-41. 2005
  10. pmc Transgenic inhibition of glial NF-kappa B reduces pain behavior and inflammation after peripheral nerve injury
    Eugene S Fu
    Department of Anesthesiology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Pain 148:509-18. 2010

Collaborators

Detail Information

Publications14

  1. doi request reprint Transgenic inhibition of astroglial NF-kappa B leads to increased axonal sparing and sprouting following spinal cord injury
    Roberta Brambilla
    Department of Neurological Surgery, University of Miami, Florida 33136, USA
    J Neurochem 110:765-78. 2009
    ....
  2. pmc Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination
    Roberta Brambilla
    The Miami Project to Cure Paralysis, Miller School of Medicine, University of Miami 1095 NW 14th Terrace, Miami, FL 33136, USA
    Brain 134:2736-54. 2011
    ....
  3. doi request reprint Transgenic inhibition of astroglial NF-kappa B improves functional outcome in experimental autoimmune encephalomyelitis by suppressing chronic central nervous system inflammation
    Roberta Brambilla
    The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, 1095 Northwest 14th Terrace, Miami, FL 33136, USA
    J Immunol 182:2628-40. 2009
    ..Our data indicate that inhibiting NF-kappaB in astrocytes results in neuroprotective effects following experimental autoimmune encephalomyelitis, directly implicating astrocytes in the pathophysiology of this disease...
  4. pmc Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury
    Roberta Brambilla
    The Miami Project to Cure Paralysis, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    J Exp Med 202:145-56. 2005
    ....
  5. pmc Transgenic inhibition of astroglial NF-κB protects from optic nerve damage and retinal ganglion cell loss in experimental optic neuritis
    Roberta Brambilla
    Department of Neurological Surgery, The Miami Project to Cure Paralysis, Miller School of Medicine, University of Miami, FL 33136, USA
    J Neuroinflammation 9:213. 2012
    ..However, to date, there is no conclusive evidence to support such a causal role for infiltrating peripheral immune cells in the etiopathology of optic neuritis...
  6. pmc Inactivation of astroglial NF-kappa B promotes survival of retinal neurons following ischemic injury
    Galina Dvoriantchikova
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA
    Eur J Neurosci 30:175-85. 2009
    ..The inhibition of these pathways in astrocytes may represent a feasible neuroprotective strategy for retinal ischemia and stroke...
  7. doi request reprint Glial NF-κB inhibition alters neuropeptide expression after sciatic nerve injury in mice
    Yan Ping Zhang
    Department of Anesthesiology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Brain Res 1385:38-46. 2011
    ..Our results showed that glial NF-κB inhibition reduces galanin and CGRP expression, which are neuropeptides that correlate with pain behavior and inflammation after peripheral nerve injury...
  8. ncbi request reprint Astroglial nuclear factor-kappaB regulates learning and memory and synaptic plasticity in female mice
    Valerie Bracchi-Ricard
    The Miami Project to Cure Paralysis, Department of Neurological Surgery, University of Miami School of Medicine, Miami, Florida 33136, USA
    J Neurochem 104:611-23. 2008
    ..These findings indicate that astroglial NF-kappaB is an important regulator of learning/memory and synaptic plasticity...
  9. pmc NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation
    Wen Hui Hu
    The Miami Project to Cure Paralysis, Department of Neurological Surgery, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    J Biol Chem 280:29233-41. 2005
    ..Because of its neuronal expression, we propose that NIBP may be a potential target for modulating the NF-(kappa)B signaling cascade in neuronal pathologies dependent upon abnormal activation of this pathway...
  10. pmc Transgenic inhibition of glial NF-kappa B reduces pain behavior and inflammation after peripheral nerve injury
    Eugene S Fu
    Department of Anesthesiology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Pain 148:509-18. 2010
    ..These findings suggest that targeting the inflammatory response in Schwann cells and satellite cells may be important in treating neuropathic pain...
  11. doi request reprint IL7Rα contributes to experimental autoimmune encephalomyelitis through altered T cell responses and nonhematopoietic cell lineages
    Jessica J Ashbaugh
    Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    J Immunol 190:4525-34. 2013
    ..Taken together, these data indicate that multiple cell types use IL7Rα signaling in the development of EAE, and inhibition of this pathway should be considered as a new therapeutic avenue for MS...
  12. doi request reprint Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppressing remyelination
    Roberta Brambilla
    The Miami Project to Cure Paralysis, Department of Neurological Surgery, Miller School of Medicine, University of Miami, Miami, Florida The Neuroscience Program, Miller School of Medicine, University of Miami, Miami, Florida
    Glia 62:452-67. 2014
    ..glia 2014;62:452-467. ..
  13. doi request reprint The effect of stroke on immune function
    Roberta Brambilla
    The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL, United States
    Mol Cell Neurosci 53:26-33. 2013
    ..This article is part of a Special Issue entitled 'Neuroinflammation in neurodegeneration and neurodysfunction'...
  14. ncbi request reprint TNAP, a novel repressor of NF-kappaB-inducing kinase, suppresses NF-kappaB activation
    Wen Hui Hu
    Miami Project to Cure Paralysis, University of Miami School of Medicine, Miami, Florida 33136, USA
    J Biol Chem 279:35975-83. 2004
    ..These data suggest that TNAP is a repressor of NIK activity and regulates both the classical and alternative NF-kappaB signaling pathways...