Research Topics
| B M BrainardSummaryAffiliation: University of Georgia Country: USA Publications
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Detail Information
Publications
Evaluation of induction characteristics and hypnotic potency of isoflurane and sevoflurane in healthy dogsErik H Hofmeister
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
Am J Vet Res 69:451-6. 2008..To determine induction characteristics and the minimum alveolar concentration (MAC) at which consciousness returned (MACawake) in dogs anesthetized with isoflurane or sevoflurane...
Viscoelastic pharmacodynamics after dalteparin administration to healthy dogsBenjamin M Brainard
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
Am J Vet Res 73:1577-82. 2012..To evaluate the pharmacodynamic effects of dalteparin in dogs by means of viscoelastic coagulation monitoring with a thromboelastograph and a dynamic viscoelastic coagulometer...
Treatment with aspirin or clopidogrel does not affect equine platelet expression of P selectin or platelet-neutrophil aggregatesBenjamin M Brainard
College of Veterinary Medicine, University of Georgia, 501 D W Brooks Dr, Athens, GA 30602, USA
Vet Immunol Immunopathol 149:119-25. 2012..Due to small numbers of horses, this study may have been underpowered to detect a true decrease in expression, and differences between therapies may have been more pronounced if this study had evaluated horses with systemic inflammation...
RECOVER evidence and knowledge gap analysis on veterinary CPR. Part 5: MonitoringBenjamin M Brainard
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602 7371, USA
J Vet Emerg Crit Care (San Antonio) 22:S65-84. 2012..To systematically examine the evidence on patient monitoring before, during, and following veterinary CPR and to identify scientific knowledge gaps...
The effects of cytochalasin D and abciximab on hemostasis in canine whole blood assessed by thromboelastography and the PFA-100® platelet function analyzer systemBenjamin M Brainard
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, 501 D W Brooks Drive, Athens, GA 30602, USA
J Vet Diagn Invest 23:698-703. 2011..Abciximab does, however, inhibit platelet aggregation under shear stress as measured by the PFA-100. Inhibition of canine platelet function with cytochalasin D may allow further TEG studies in dogs with clinical disease...
Defects in coagulation encountered in small animal critical careBenjamin M Brainard
Department of Small Animal Medicine and Surgery, University of Georgia, 501 D W Brooks Drive, Athens, GA 30602, USA
Vet Clin North Am Small Anim Pract 41:783-803, vii. 2011..Pathophysiology, diagnosis, and treatment of coagulation dysfunction are discussed. Defects in coagulation in small animal patients are complex and a consensus on diagnosis and treatment has yet to be reached...
Effects of clopidogrel and aspirin on platelet aggregation, thromboxane production, and serotonin secretion in horsesB M Brainard
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
J Vet Intern Med 25:116-22. 2011..Critically ill horses are susceptible to thrombotic disease, which might be related to increased platelet reactivity and activation...
Pharmacodynamic and pharmacokinetic evaluation of clopidogrel and the carboxylic acid metabolite SR 26334 in healthy dogsBenjamin M Brainard
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
Am J Vet Res 71:822-30. 2010..To determine pharmacodynamic and pharmacokinetic properties of clopidogrel and the metabolite SR 26334 in dogs...
The effects of surgery and anesthesia on blood magnesium and calcium concentrations in canine and feline patientsBenjamin M Brainard
Section of Critical Care, Department of Clinical Studies, Matthew J Ryan Hospital of the Veterinary School, University of Pennsylvania, Pennsylvania, PA, USA
Vet Anaesth Analg 34:89-98. 2007..To demonstrate the effect of anesthesia and surgery on serum ionized magnesium and ionized calcium concentrations in clinical canine and feline patients...
Tracheostomy in the giant anteater (Myrmecophaga tridactyla)Benjamin M Brainard
Department of Clinical Studies, Veterinary Hospital of the University of Pennsylvania, 3900 Delancey Street, Philadelphia, Pennsylvania 19104, USA
J Zoo Wildl Med 39:655-8. 2008..This procedure, however, appears to be a feasible method to achieve endotracheal intubation in the anteater...
Thrombelastography in horses with acute gastrointestinal diseaseK L Epstein
Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, USA
J Vet Intern Med 25:307-14. 2011..Coagulopathies in horses with gastrointestinal disease are frequently identified and associated with morbidity and fatality...
Pharmacokinetic assessment of ketanserin in the horseI A Aljuffali
Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, GA 30602 2352, USA
J Vet Pharmacol Ther 35:472-7. 2012..87 L/h/kg. Model simulations followed by the examination in three healthy horses suggest 0.3 mg/kg q.8 h exhibited linear PK and produced consistent systemic blood concentrations of ketanserin above 3 ng/mL...
Thrombelastography in 26 healthy horses with and without activation by recombinant human tissue factorKira L Epstein
Department of Large Animal Medicine, University of Georgia, Athens, GA, USA
J Vet Emerg Crit Care (San Antonio) 19:96-101. 2009..To determine reference intervals for TEG parameters in the horse, and to determine if traditional coagulation tests correlate with TEG. Design: Prospective, observational...
Evaluating of veterinarians' and veterinary students' knowledge and clinical use of pulse oximetryErik H Hoffmeister
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA
J Vet Med Educ 32:272-7. 2005..We hypothesized that veterinarians and veterinary students may lack key knowledge about pulse oximetry, which may result in this type of patient monitor not being used on appropriate patient populations or to its full capabilities...
Effects of graded doses of propofol for anesthesia induction on cardiovascular parameters and intraocular pressures in normal dogsErik H Hofmeister
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
Vet Anaesth Analg 36:442-8. 2009..To determine the effects of graded doses of propofol on cardiovascular parameters and intraocular pressures (IOP) in normal dogs...
Sonoclot® evaluation of single- and multiple-dose subcutaneous unfractionated heparin therapy in healthy adult dogsD M Babski
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
J Vet Intern Med 26:631-8. 2012..While laboratory measurements of activated partial thromboplasin time (aPTT) and Anti-Xa activity (AXA) accurately describe heparin effect, their availability is limited...
Bilateral renal ischemia as a model of acute kidney injury in catsC W Schmiedt
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
Res Vet Sci 93:950-9. 2012..No changes were detected in BP. Platelet count and hematocrit decreased markedly after ischemia and reperfusion. Sixty minutes bilateral renal ischemia is an effective model for acute renal injury...
An evaluation of the Abaxis VSPro for the measurement of equine plasma fibrinogen concentrationsK L Epstein
Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA
Equine Vet J 44:449-52. 2012..Accurate measurement of plasma fibrinogen concentrations is an important tool for assessment of horses with inflammatory diseases...
Clinical and clinicopathologic effects of plateletpheresis on healthy donor dogsMary Beth Callan
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6010, USA
Transfusion 48:2214-21. 2008..The safety and feasibility of plateletpheresis using a commercially available apheresis system (COBE Spectra, Gambro BCT) were evaluated in donor dogs, with characterization of its clinical and clinicopathologic effects...
The effect of unfractionated heparin on thrombelastographic analysis in healthy dogsJennifer R Pittman
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
J Vet Emerg Crit Care (San Antonio) 20:216-23. 2010..To determine the effect of single and multiple doses of SQ heparin (200 U/kg) on the thrombelastogram of healthy dogs...
Changes in platelet function, hemostasis, and prostaglandin expression after treatment with nonsteroidal anti-inflammatory drugs with various cyclooxygenase selectivities in dogsBenjamin M Brainard
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens GA 30602, USA
Am J Vet Res 68:251-7. 2007..To determine the effects of nonsteroidal anti-inflammatory drugs of various cyclooxygenase selectivities on hemostasis and prostaglandin expression in dogs...
Prognostic indicators for dogs and cats with cardiopulmonary arrest treated by cardiopulmonary cerebral resuscitation at a university teaching hospitalErik H Hofmeister
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
J Am Vet Med Assoc 235:50-7. 2009....
Comparison of recovery from anesthesia with isoflurane, sevoflurane, or desflurane in healthy dogsLuis A Lopez
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
Am J Vet Res 70:1339-44. 2009..To determine the quality and speed of recovery from anesthesia with isoflurane, sevoflurane, or desflurane and determine end-tidal inhalant concentration at certain events during recovery in healthy dogs...
