David A Brafman

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions
    D A Brafman
    Department of Cellular and Molecular Medicine, Stem Cell Program, University of California, La Jolla, CA 92093, USA
    Cell Death Differ 20:369-81. 2013
  2. ncbi Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments
    David A Brafman
    Department of Bioengineering, University of California, San Diego, USA
    Integr Biol (Camb) 1:513-24. 2009
  3. ncbi Arrayed cellular microenvironments for identifying culture and differentiation conditions for stem, primary and rare cell populations
    David A Brafman
    Cellular and Molecular Medicine, Stem Cell Program, University of California, San Diego, California, USA
    Nat Protoc 7:703-17. 2012
  4. ncbi Defining long-term maintenance conditions of human embryonic stem cells with arrayed cellular microenvironment technology
    David A Brafman
    Department of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0412, USA
    Stem Cells Dev 18:1141-54. 2009
  5. ncbi Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces
    David A Brafman
    Department of Bioengineering, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0695, United States
    Biomaterials 31:9135-44. 2010

Detail Information

Publications5

  1. ncbi Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions
    D A Brafman
    Department of Cellular and Molecular Medicine, Stem Cell Program, University of California, La Jolla, CA 92093, USA
    Cell Death Differ 20:369-81. 2013
    ..These data provide evidence that FN and VTN promote endoderm differentiation of hESCs through interaction with ITGA5 and ITGAV, and that ECMP-integrin interactions are required for hESC differentiation into functionally mature cells...
  2. ncbi Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments
    David A Brafman
    Department of Bioengineering, University of California, San Diego, USA
    Integr Biol (Camb) 1:513-24. 2009
    ..Our results indicate that array-based screens may provide an efficient means for identifying candidate signaling pathways to be targeted for anti-fibrotic therapies...
  3. ncbi Arrayed cellular microenvironments for identifying culture and differentiation conditions for stem, primary and rare cell populations
    David A Brafman
    Cellular and Molecular Medicine, Stem Cell Program, University of California, San Diego, California, USA
    Nat Protoc 7:703-17. 2012
    ..A standard ACME screen uses the technologies previously applied to the manufacture and analysis of DNA microarrays, requires standard cell-culture facilities and can be performed from beginning to end within 5-10 days...
  4. ncbi Defining long-term maintenance conditions of human embryonic stem cells with arrayed cellular microenvironment technology
    David A Brafman
    Department of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0412, USA
    Stem Cells Dev 18:1141-54. 2009
    ..In the future, the novel array platform and analysis procedure presented here will be applied toward the directed differentiation of hESCs and maintenance of other stem and progenitor cell populations...
  5. ncbi Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces
    David A Brafman
    Department of Bioengineering, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0695, United States
    Biomaterials 31:9135-44. 2010
    ....