Birgit G Bradel-Tretheway

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy
    Pauline Chugh
    Department of Microbiology and Immunology, School of Medicine, University of Rochester Medical Center 601 Elmwood Avenue Box 672 Rochester, New York 14742 USA
    Retrovirology 5:11. 2008
  2. pmc The human H5N1 influenza A virus polymerase complex is active in vitro over a broad range of temperatures, in contrast to the WSN complex, and this property can be attributed to the PB2 subunit
    Birgit G Bradel-Tretheway
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Gen Virol 89:2923-32. 2008

Collaborators

  • Pauline Chugh
  • Stephen Dewhurst
  • Vicente Planelles
  • Sanjay B Maggirwar
  • Baek Kim
  • Carlos M R Monteiro-Filho

Detail Information

Publications2

  1. pmc Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy
    Pauline Chugh
    Department of Microbiology and Immunology, School of Medicine, University of Rochester Medical Center 601 Elmwood Avenue Box 672 Rochester, New York 14742 USA
    Retrovirology 5:11. 2008
    ..Unlike CD4+ T cells, HIV-1 infected macrophages exhibit extended life span even upon stress, consistent with their in vivo role as long-lived HIV-1 reservoirs...
  2. pmc The human H5N1 influenza A virus polymerase complex is active in vitro over a broad range of temperatures, in contrast to the WSN complex, and this property can be attributed to the PB2 subunit
    Birgit G Bradel-Tretheway
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Gen Virol 89:2923-32. 2008
    ..These results show that PB2 plays an important role in regulating the temperature optimum for IAV RNA polymerase activity, possibly due to effects on the functional stability of the 3P complex...