Christopher L Brace

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Tissue contraction caused by radiofrequency and microwave ablation: a laboratory study in liver and lung
    Christopher L Brace
    Department of Radiology, University of Wisconsin, 1111 Highland Avenue, Room 1303, Madison, WI 53705, USA
    J Vasc Interv Radiol 21:1280-6. 2010
  2. pmc Dual-slot antennas for microwave tissue heating: parametric design analysis and experimental validation
    Christopher L Brace
    Departments of Radiology and Biomedical Engineering, University of Wisconsin, Madison, Wisconsin 53792, USA
    Med Phys 38:4232-40. 2011
  3. pmc Periodic contrast-enhanced computed tomography for thermal ablation monitoring: a feasibility study
    Christopher L Brace
    Department of Radiology, University of Wisconsin, Madison, WI 53705, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:4299-302. 2009
  4. pmc Pulmonary thermal ablation: comparison of radiofrequency and microwave devices by using gross pathologic and CT findings in a swine model
    Christopher L Brace
    Department of Radiology, University of Wisconsin, Clinical Sciences Center, E1 322, 600 Highland Ave, Madison, WI 53792 3252, USA
    Radiology 251:705-11. 2009
  5. pmc Radiofrequency and microwave ablation of the liver, lung, kidney, and bone: what are the differences?
    Christopher L Brace
    Department of Radiology, University of Wisconsin, Madison, WI 53792 3252, USA
    Curr Probl Diagn Radiol 38:135-43. 2009
  6. pmc Microwave ablation technology: what every user should know
    Christopher L Brace
    Department of Radiology, University of Wisconsin, Madison, WI 53792 3252, USA
    Curr Probl Diagn Radiol 38:61-7. 2009
  7. doi request reprint Temperature-dependent dielectric properties of liver tissue measured during thermal ablation: toward an improved numerical model
    Christopher L Brace
    University of Wisconsin, Madison, WI 53792, USA
    Conf Proc IEEE Eng Med Biol Soc 2008:230-3. 2008
  8. pmc Radiofrequency ablation: simultaneous application of multiple electrodes via switching creates larger, more confluent ablations than sequential application in a large animal model
    Christopher L Brace
    Department of Radiology, University of Wisconsin, Clinical Sciences Center, Madison, WI 53792, USA
    J Vasc Interv Radiol 20:118-24. 2009
  9. pmc Microwave tissue ablation: biophysics, technology, and applications
    Christopher L Brace
    Department of Radiology, University of Wisconsin, Madison, WI 53705, USA
    Crit Rev Biomed Eng 38:65-78. 2010
  10. ncbi request reprint Electrical isolation during radiofrequency ablation: 5% dextrose in water provides better protection than saline
    Christopher L Brace
    Department of Radiology, Wisconsin University, Madison, WI 53792, USA
    Conf Proc IEEE Eng Med Biol Soc 1:5021-4. 2006

Collaborators

Detail Information

Publications34

  1. pmc Tissue contraction caused by radiofrequency and microwave ablation: a laboratory study in liver and lung
    Christopher L Brace
    Department of Radiology, University of Wisconsin, 1111 Highland Avenue, Room 1303, Madison, WI 53705, USA
    J Vasc Interv Radiol 21:1280-6. 2010
    ..To determine the amount of tissue contraction during radiofrequency (RF) and microwave ablation...
  2. pmc Dual-slot antennas for microwave tissue heating: parametric design analysis and experimental validation
    Christopher L Brace
    Departments of Radiology and Biomedical Engineering, University of Wisconsin, Madison, Wisconsin 53792, USA
    Med Phys 38:4232-40. 2011
    ..Design and validate an efficient dual-slot coaxial microwave ablation antenna that produces an approximately spherical heating pattern to match the shape of most abdominal and pulmonary tumor targets...
  3. pmc Periodic contrast-enhanced computed tomography for thermal ablation monitoring: a feasibility study
    Christopher L Brace
    Department of Radiology, University of Wisconsin, Madison, WI 53705, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:4299-302. 2009
    ..Such improvements limit the amount of radiation and iodinated contrast material required to visualize the ablation zone, especially at early time points. Additional study of periodic CECT with HYPR processing appears warranted...
  4. pmc Pulmonary thermal ablation: comparison of radiofrequency and microwave devices by using gross pathologic and CT findings in a swine model
    Christopher L Brace
    Department of Radiology, University of Wisconsin, Clinical Sciences Center, E1 322, 600 Highland Ave, Madison, WI 53792 3252, USA
    Radiology 251:705-11. 2009
    ..To compare the performance of equivalently sized radiofrequency and microwave ablation applicators in a normal porcine lung model...
  5. pmc Radiofrequency and microwave ablation of the liver, lung, kidney, and bone: what are the differences?
    Christopher L Brace
    Department of Radiology, University of Wisconsin, Madison, WI 53792 3252, USA
    Curr Probl Diagn Radiol 38:135-43. 2009
    ..This article outlines the physics behind RF and microwave heating, discusses relevant properties of the liver, lung, kidney, and bone for thermal ablation and examines the roles of RF and microwave ablation in these tissues...
  6. pmc Microwave ablation technology: what every user should know
    Christopher L Brace
    Department of Radiology, University of Wisconsin, Madison, WI 53792 3252, USA
    Curr Probl Diagn Radiol 38:61-7. 2009
    ..This article attempts to provide an overview of each of these components, outline their functions and roles, and provide some insight into what every potential microwave ablation user should know about systems in development...
  7. doi request reprint Temperature-dependent dielectric properties of liver tissue measured during thermal ablation: toward an improved numerical model
    Christopher L Brace
    University of Wisconsin, Madison, WI 53792, USA
    Conf Proc IEEE Eng Med Biol Soc 2008:230-3. 2008
    ....
  8. pmc Radiofrequency ablation: simultaneous application of multiple electrodes via switching creates larger, more confluent ablations than sequential application in a large animal model
    Christopher L Brace
    Department of Radiology, University of Wisconsin, Clinical Sciences Center, Madison, WI 53792, USA
    J Vasc Interv Radiol 20:118-24. 2009
    ..To compare radiofrequency (RF) ablations created by using a sequential technique to those created simultaneously by using a switching algorithm in ex vivo and in vivo liver models...
  9. pmc Microwave tissue ablation: biophysics, technology, and applications
    Christopher L Brace
    Department of Radiology, University of Wisconsin, Madison, WI 53705, USA
    Crit Rev Biomed Eng 38:65-78. 2010
    ..This article reviews the basic biophysics of microwave tissue heating, provides an overview of the design and operation of current equipment, and outlines areas for future research...
  10. ncbi request reprint Electrical isolation during radiofrequency ablation: 5% dextrose in water provides better protection than saline
    Christopher L Brace
    Department of Radiology, Wisconsin University, Madison, WI 53792, USA
    Conf Proc IEEE Eng Med Biol Soc 1:5021-4. 2006
    ..Saline actually increased the amount of RF current in the adjacent tissue. Based on these results, we conclude that D5W is preferable to saline as a protective fluid...
  11. ncbi request reprint Microwave ablation with multiple simultaneously powered small-gauge triaxial antennas: results from an in vivo swine liver model
    Christopher L Brace
    Department of Radiology, University of Wisconsin Madison, 600 Highland Ave, Madison, WI 53792 3252, USA
    Radiology 244:151-6. 2007
    ..To prospectively investigate the ability of a single generator to power multiple small-diameter antennas and create large zones of ablation in an in vivo swine liver model...
  12. ncbi request reprint Radiofrequency ablation with a high-power generator: device efficacy in an in vivo porcine liver model
    C L Brace
    Department of Radiology, Madison, WI 53792, USA
    Int J Hyperthermia 23:387-94. 2007
    ..The purpose of this study was to test the feasibility and efficacy of using a high-power generator with nondeployable electrodes to create large zones of coagulation in an in vivo porcine liver model...
  13. pmc High-powered microwave ablation with a small-gauge, gas-cooled antenna: initial ex vivo and in vivo results
    Meghan G Lubner
    Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 3252, USA
    J Vasc Interv Radiol 23:405-11. 2012
    ..To evaluate the performance of a gas-cooled, high-powered microwave system...
  14. pmc Microwave ablation with a single small-gauge triaxial antenna: in vivo porcine liver model
    Christopher L Brace
    Department of Radiology, University of Wisconsin Madison, 600 Highland Ave, Madison, WI 53792, USA
    Radiology 242:435-40. 2007
    ..To evaluate the performance of a 17-gauge triaxial antenna at microwave ablation in an in vivo porcine liver model...
  15. pmc Microwave ablation versus radiofrequency ablation in the kidney: high-power triaxial antennas create larger ablation zones than similarly sized internally cooled electrodes
    Paul F Laeseke
    Department of Radiology, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792, USA
    J Vasc Interv Radiol 20:1224-9. 2009
    ..To determine whether microwave ablation with high-power triaxial antennas creates significantly larger ablation zones than radiofrequency (RF) ablation with similarly sized internally cooled electrodes...
  16. pmc High-powered gas-cooled microwave ablation: shaft cooling creates an effective stick function without altering the ablation zone
    Erica M Knavel
    Department of Radiology, University of Wisconsin, E3 311 CSC, 600 Highland Ave, Madison, WI 53792, USA
    AJR Am J Roentgenol 198:W260-5. 2012
    ..The purpose of our study was to validate the ability of a new gas-cooled microwave device to secure antennas into tissue before ablation via shaft cooling and to verify that such cooling does not compromise the intended ablation...
  17. doi request reprint Microwave ablation with triaxial antennas tuned for lung: results in an in vivo porcine model
    Nathan A Durick
    Department of Radiology, University of Wisconsin Madison, 600 Highland Ave, Box 3252, E3 311 CSC, Madison, WI 53792 3252, USA
    Radiology 247:80-7. 2008
    ....
  18. pmc A dual-slot microwave antenna for more spherical ablation zones: ex vivo and in vivo validation
    Jason Chiang
    Departments of Radiology, Biomedical Engineering, and Chemistry, University of Wisconsin, 1111 Highland Ave, WIMR 1303 O, Madison, WI 53705, USA
    Radiology 268:382-9. 2013
    ..To compare the performance of a microwave antenna design with two annular slots to that of a monopole antenna design in creating a more spherical ablation zone...
  19. pmc Contrast media-doped hydrodissection during thermal ablation: optimizing contrast media concentration for improved visibility on CT images
    Calista Campbell
    Department of Radiology, University of Wisconsin Madison, Madison, WI 53705, USA
    AJR Am J Roentgenol 199:677-82. 2012
    ....
  20. pmc Young's modulus reconstruction for radio-frequency ablation electrode-induced displacement fields: a feasibility study
    Jingfeng Jiang
    Medical Physics Department, University of Wisconsin, Madison, WI 53705, USA
    IEEE Trans Med Imaging 28:1325-34. 2009
    ..In both experiments, the geometries of the reconstructed modulus images of thermal ablation zones match well with the phantom design and the gross pathology image, respectively...
  21. pmc Tumor boundary estimation through time-domain peaks monitoring: numerical predictions and experimental results in tissue-mimicking phantoms
    Peng Wang
    Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706, USA
    IEEE Trans Biomed Eng 56:2634-41. 2009
    ..Additional work is needed to validate and optimize this method in tumor models...
  22. ncbi request reprint Multiple-electrode radiofrequency ablation creates confluent areas of necrosis: in vivo porcine liver results
    Paul F Laeseke
    Department of Radiology, University of Wisconsin, Box 3252, Clinical Science Center E3, 600 Highland Ave, Madison, WI 53792, USA
    Radiology 241:116-24. 2006
    ..To prospectively evaluate, in vivo in pigs, an impedance-based multiple-electrode radiofrequency (RF) ablation system for creation of confluent areas of hepatic coagulation...
  23. pmc A comparison of direct heating during radiofrequency and microwave ablation in ex vivo liver
    Anita Andreano
    Department of Radiology, University of Wisconsin, WIMR 1141, 1111 Highland Ave, Madison, WI 53705, USA
    Cardiovasc Intervent Radiol 36:505-11. 2013
    ..This study was designed to determine the magnitude and spatial distribution of temperature elevations when using 480 kHz RF and 2.45 GHz microwave energy in ex vivo liver models...
  24. pmc Quantifying local stiffness variations in radiofrequency ablations with dynamic indentation
    Ryan J DeWall
    Department of Medical Physics, University of Wisconsin Madison, Madison, WI 53705, USA
    IEEE Trans Biomed Eng 59:728-35. 2012
    ....
  25. pmc Microwave tumor ablation: mechanism of action, clinical results, and devices
    Meghan G Lubner
    Department of Radiology, University of Wisconsin, E3 311 Clinical Sciences Center, 600 Highland Ave, Madison, WI 53792 3252, USA
    J Vasc Interv Radiol 21:S192-203. 2010
    ..As a result, larger, more customizable ablation zones may be created in less time. Although multiple microwave ablation systems are currently available, further study and continued development are needed...
  26. pmc Optimizing the protocol for pulmonary cryoablation: a comparison of a dual- and triple-freeze protocol
    J Louis Hinshaw
    Department of Radiology, University of Wisconsin, Mail Code 3252, 600 Highland Ave, Madison, WI 53792 3252, USA
    Cardiovasc Intervent Radiol 33:1180-5. 2010
    ....
  27. pmc Computational modelling of microwave tumour ablations
    Jason Chiang
    Department of Radiology, University of Wisconsin, Madison, WI 53705, USA
    Int J Hyperthermia 29:308-17. 2013
    ..This review will discuss the basic theory, current trends and future direction of computational modelling of microwave ablations...
  28. pmc Tissue dielectric measurement using an interstitial dipole antenna
    Peng Wang
    Department ofMedical Physics, University ofWisconsin Madison, Madison, WI 53705, USA
    IEEE Trans Biomed Eng 59:115-21. 2012
    ..Further development of this technique may facilitate real-time monitoring of microwave ablation treatments through the treatment applicator...
  29. pmc Expanded modeling of temperature-dependent dielectric properties for microwave thermal ablation
    Zhen Ji
    Department of Radiology, University of Wisconsin Madison, Madison, WI, USA
    Phys Med Biol 56:5249-64. 2011
    ..We can conclude from these studies that a sigmoidal model of tissue dielectric properties improves prediction of experimental results. More work is needed to refine and generalize this model...
  30. doi request reprint Does selective intubation increase ablation zone size during pulmonary cryoablation?
    J Louis Hinshaw
    Department of Radiology, University of Wisconsin, E3 311 CSC, 600 Highland Ave, Madison, WI 53792, USA
    J Vasc Interv Radiol 19:1497-501. 2008
    ..To determine the effect of selective intubation on ablation zone size during pulmonary cryoablation...
  31. pmc Thermal ablation of lung tumors
    P David Sonntag
    Department of Radiology, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792, USA
    Surg Oncol Clin N Am 20:369-87, ix. 2011
    ..The article compares and contrasts the three major thermal ablation modalities: radiofrequency ablation, microwave ablation, and cryoablation...
  32. doi request reprint Principles of and advances in percutaneous ablation
    Muneeb Ahmed
    Laboratory for Minimally Invasive Tumor Therapy, Section of Interventional Radiology, and Section of Abdominal Imaging, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 1 Deaconess Rd, Boston, MA 02215, USA
    Radiology 258:351-69. 2011
    ..Advances in technique will also be covered, including combination therapies, tissue property modulation, and the role of computer modeling for treatment optimization...
  33. pmc Flow-dependent vascular heat transfer during microwave thermal ablation
    Jason Chiang
    Department of Radiology and BiomedicalEngineering, University of Wisconsin, Madison, 53705 USA
    Conf Proc IEEE Eng Med Biol Soc 2012:5582-5. 2012
    ..High-flow conditions create the more familiar heat-sink effect that can protect perivascular tissues from the intended thermal damage. These results may help guide placement and use of microwave ablation technologies in future studies...
  34. doi request reprint Tumor ablation: common modalities and general practices
    Erica M Knavel
    Department of Radiology, University of Wisconsin Madison, Clinical Sciences Center, Madison, WI Electronic address
    Tech Vasc Interv Radiol 16:192-200. 2013
    ..Each technique, although similar in purpose, has specific and optimal indications. This review serves to discuss general principles and technique, reviews each modality, and discusses modality selection. ..

Research Grants2

  1. Optimizing microwave ablation techniques for targeted cancer therapy
    Christopher L Brace; Fiscal Year: 2010
    ....
  2. Periodic Contrast-Enhanced CT With HYPR Reconstruction For Ablation Monitoring
    Christopher L Brace; Fiscal Year: 2010
    ..abstract_text> ..