Research Topics
| Christopher L BraceSummaryAffiliation: University of Wisconsin Country: USA Publications
Research Grants
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Detail Information
Publications
Periodic contrast-enhanced computed tomography for thermal ablation monitoring: a feasibility studyChristopher L Brace
Department of Radiology, University of Wisconsin, Madison, WI 53705, USA
Conf Proc IEEE Eng Med Biol Soc 2009:4299-302. 2009..Such improvements limit the amount of radiation and iodinated contrast material required to visualize the ablation zone, especially at early time points. Additional study of periodic CECT with HYPR processing appears warranted...- Microwave tissue ablation: biophysics, technology, and applicationsChristopher L Brace
Department of Radiology, University of Wisconsin, Madison, WI 53705, USA
Crit Rev Biomed Eng 38:65-78. 2010..This article reviews the basic biophysics of microwave tissue heating, provides an overview of the design and operation of current equipment, and outlines areas for future research... - Dual-slot antennas for microwave tissue heating: parametric design analysis and experimental validationChristopher L Brace
Departments of Radiology and Biomedical Engineering, University of Wisconsin, Madison, Wisconsin 53792, USA
Med Phys 38:4232-40. 2011..Design and validate an efficient dual-slot coaxial microwave ablation antenna that produces an approximately spherical heating pattern to match the shape of most abdominal and pulmonary tumor targets... - Pulmonary thermal ablation: comparison of radiofrequency and microwave devices by using gross pathologic and CT findings in a swine modelChristopher L Brace
Department of Radiology, University of Wisconsin, Clinical Sciences Center, E1 322, 600 Highland Ave, Madison, WI 53792 3252, USA
Radiology 251:705-11. 2009..To compare the performance of equivalently sized radiofrequency and microwave ablation applicators in a normal porcine lung model... - Radiofrequency and microwave ablation of the liver, lung, kidney, and bone: what are the differences?Christopher L Brace
Department of Radiology, University of Wisconsin, Madison, WI 53792 3252, USA
Curr Probl Diagn Radiol 38:135-43. 2009..This article outlines the physics behind RF and microwave heating, discusses relevant properties of the liver, lung, kidney, and bone for thermal ablation and examines the roles of RF and microwave ablation in these tissues... - Microwave ablation technology: what every user should knowChristopher L Brace
Department of Radiology, University of Wisconsin, Madison, WI 53792 3252, USA
Curr Probl Diagn Radiol 38:61-7. 2009..This article attempts to provide an overview of each of these components, outline their functions and roles, and provide some insight into what every potential microwave ablation user should know about systems in development... 
Temperature-dependent dielectric properties of liver tissue measured during thermal ablation: toward an improved numerical modelChristopher L Brace
University of Wisconsin, Madison, WI 53792, USA
Conf Proc IEEE Eng Med Biol Soc 2008:230-3. 2008....- Radiofrequency ablation: simultaneous application of multiple electrodes via switching creates larger, more confluent ablations than sequential application in a large animal modelChristopher L Brace
Department of Radiology, University of Wisconsin, Clinical Sciences Center, Madison, WI 53792, USA
J Vasc Interv Radiol 20:118-24. 2009..To compare radiofrequency (RF) ablations created by using a sequential technique to those created simultaneously by using a switching algorithm in ex vivo and in vivo liver models... 
Electrical isolation during radiofrequency ablation: 5% dextrose in water provides better protection than salineChristopher L Brace
Department of Radiology, Wisconsin University, Madison, WI 53792, USA
Conf Proc IEEE Eng Med Biol Soc 1:5021-4. 2006..Saline actually increased the amount of RF current in the adjacent tissue. Based on these results, we conclude that D5W is preferable to saline as a protective fluid...- Microwave ablation with multiple simultaneously powered small-gauge triaxial antennas: results from an in vivo swine liver modelChristopher L Brace
Department of Radiology, University of Wisconsin Madison, 600 Highland Ave, Madison, WI 53792 3252, USA
Radiology 244:151-6. 2007..To prospectively investigate the ability of a single generator to power multiple small-diameter antennas and create large zones of ablation in an in vivo swine liver model... - Radiofrequency ablation with a high-power generator: device efficacy in an in vivo porcine liver modelC L Brace
Department of Radiology, Madison, WI 53792, USA
Int J Hyperthermia 23:387-94. 2007..The purpose of this study was to test the feasibility and efficacy of using a high-power generator with nondeployable electrodes to create large zones of coagulation in an in vivo porcine liver model... - Tissue contraction caused by radiofrequency and microwave ablation: a laboratory study in liver and lungChristopher L Brace
Department of Radiology, University of Wisconsin, 1111 Highland Avenue, Room 1303, Madison, WI 53705, USA
J Vasc Interv Radiol 21:1280-6. 2010..To determine the amount of tissue contraction during radiofrequency (RF) and microwave ablation... - High-powered microwave ablation with a small-gauge, gas-cooled antenna: initial ex vivo and in vivo resultsMeghan G Lubner
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 3252, USA
J Vasc Interv Radiol 23:405-11. 2012..To evaluate the performance of a gas-cooled, high-powered microwave system... - Microwave ablation versus radiofrequency ablation in the kidney: high-power triaxial antennas create larger ablation zones than similarly sized internally cooled electrodesPaul F Laeseke
Department of Radiology, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792, USA
J Vasc Interv Radiol 20:1224-9. 2009..To determine whether microwave ablation with high-power triaxial antennas creates significantly larger ablation zones than radiofrequency (RF) ablation with similarly sized internally cooled electrodes... - Microwave ablation with a single small-gauge triaxial antenna: in vivo porcine liver modelChristopher L Brace
Department of Radiology, University of Wisconsin Madison, 600 Highland Ave, Madison, WI 53792, USA
Radiology 242:435-40. 2007..To evaluate the performance of a 17-gauge triaxial antenna at microwave ablation in an in vivo porcine liver model... - High-powered gas-cooled microwave ablation: shaft cooling creates an effective stick function without altering the ablation zoneErica M Knavel
Department of Radiology, University of Wisconsin, E3 311 CSC, 600 Highland Ave, Madison, WI 53792, USA
AJR Am J Roentgenol 198:W260-5. 2012..The purpose of our study was to validate the ability of a new gas-cooled microwave device to secure antennas into tissue before ablation via shaft cooling and to verify that such cooling does not compromise the intended ablation... - Microwave ablation with triaxial antennas tuned for lung: results in an in vivo porcine modelNathan A Durick
Department of Radiology, University of Wisconsin Madison, 600 Highland Ave, Box 3252, E3 311 CSC, Madison, WI 53792 3252, USA
Radiology 247:80-7. 2008.... - Contrast media-doped hydrodissection during thermal ablation: optimizing contrast media concentration for improved visibility on CT imagesCalista Campbell
Department of Radiology, University of Wisconsin Madison, Madison, WI 53705, USA
AJR Am J Roentgenol 199:677-82. 2012.... - Multiple-electrode radiofrequency ablation creates confluent areas of necrosis: in vivo porcine liver resultsPaul F Laeseke
Department of Radiology, University of Wisconsin, Box 3252, Clinical Science Center E3, 600 Highland Ave, Madison, WI 53792, USA
Radiology 241:116-24. 2006..To prospectively evaluate, in vivo in pigs, an impedance-based multiple-electrode radiofrequency (RF) ablation system for creation of confluent areas of hepatic coagulation... - Young's modulus reconstruction for radio-frequency ablation electrode-induced displacement fields: a feasibility studyJingfeng Jiang
Medical Physics Department, University of Wisconsin, Madison, WI 53705, USA
IEEE Trans Med Imaging 28:1325-34. 2009..In both experiments, the geometries of the reconstructed modulus images of thermal ablation zones match well with the phantom design and the gross pathology image, respectively... - Tumor boundary estimation through time-domain peaks monitoring: numerical predictions and experimental results in tissue-mimicking phantomsPeng Wang
Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706, USA
IEEE Trans Biomed Eng 56:2634-41. 2009..Additional work is needed to validate and optimize this method in tumor models... - Quantifying local stiffness variations in radiofrequency ablations with dynamic indentationRyan J DeWall
Department of Medical Physics, University of Wisconsin Madison, Madison, WI 53705, USA
IEEE Trans Biomed Eng 59:728-35. 2012.... - Microwave tumor ablation: mechanism of action, clinical results, and devicesMeghan G Lubner
Department of Radiology, University of Wisconsin, E3 311 Clinical Sciences Center, 600 Highland Ave, Madison, WI 53792 3252, USA
J Vasc Interv Radiol 21:S192-203. 2010..As a result, larger, more customizable ablation zones may be created in less time. Although multiple microwave ablation systems are currently available, further study and continued development are needed... - Optimizing the protocol for pulmonary cryoablation: a comparison of a dual- and triple-freeze protocolJ Louis Hinshaw
Department of Radiology, University of Wisconsin, Mail Code 3252, 600 Highland Ave, Madison, WI 53792 3252, USA
Cardiovasc Intervent Radiol 33:1180-5. 2010.... - Tissue dielectric measurement using an interstitial dipole antennaPeng Wang
Department ofMedical Physics, University ofWisconsin Madison, Madison, WI 53705, USA
IEEE Trans Biomed Eng 59:115-21. 2012..Further development of this technique may facilitate real-time monitoring of microwave ablation treatments through the treatment applicator... - Expanded modeling of temperature-dependent dielectric properties for microwave thermal ablationZhen Ji
Department of Radiology, University of Wisconsin Madison, Madison, WI, USA
Phys Med Biol 56:5249-64. 2011..We can conclude from these studies that a sigmoidal model of tissue dielectric properties improves prediction of experimental results. More work is needed to refine and generalize this model... - Does selective intubation increase ablation zone size during pulmonary cryoablation?J Louis Hinshaw
Department of Radiology, University of Wisconsin, E3 311 CSC, 600 Highland Ave, Madison, WI 53792, USA
J Vasc Interv Radiol 19:1497-501. 2008..To determine the effect of selective intubation on ablation zone size during pulmonary cryoablation... - Thermal ablation of lung tumorsP David Sonntag
Department of Radiology, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792, USA
Surg Oncol Clin N Am 20:369-87, ix. 2011..The article compares and contrasts the three major thermal ablation modalities: radiofrequency ablation, microwave ablation, and cryoablation... - Principles of and advances in percutaneous ablationMuneeb Ahmed
Laboratory for Minimally Invasive Tumor Therapy, Section of Interventional Radiology, and Section of Abdominal Imaging, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 1 Deaconess Rd, Boston, MA 02215, USA
Radiology 258:351-69. 2011..Advances in technique will also be covered, including combination therapies, tissue property modulation, and the role of computer modeling for treatment optimization... - A comparison of direct heating during radiofrequency and microwave ablation in ex vivo liverAnita Andreano
Department of Radiology, University of Wisconsin, WIMR 1141, 1111 Highland Ave, Madison, WI 53705, USA
Cardiovasc Intervent Radiol 36:505-11. 2013..This study was designed to determine the magnitude and spatial distribution of temperature elevations when using 480 kHz RF and 2.45 GHz microwave energy in ex vivo liver models...
Research Grants
- Optimizing microwave ablation techniques for targeted cancer therapyChristopher L Brace; Fiscal Year: 2010....
- Periodic Contrast-Enhanced CT With HYPR Reconstruction For Ablation MonitoringChristopher L Brace; Fiscal Year: 2010..abstract_text> ..