Research Topics
| Adel BozorgzadehSummaryAffiliation: University of Rochester Country: USA Publications
| Collaborators
|
Detail Information
Publications
Survival outcomes in liver transplantation for hepatocellular carcinoma, comparing impact of hepatitis C versus other etiology of cirrhosisAdel Bozorgzadeh
Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA
Liver Transpl 13:807-13. 2007..Our results suggest that Milan selection criteria may be too limiting and lose their predictive power when applied to patients without HCV infection...
Pharmacokinetics of mycophenolic acid in live donor liver transplant patients vs deceased donor liver transplant patientsAshok Jain
University of Rochester Medical Center, Department of Surgery, Division of Solid Organ Transplantation, Rochester, NY 14642, USA
J Clin Pharmacol 48:547-52. 2008..These observations point to the need to use a lower dosage (approximately 30%) of mycophenolate mofetil in live donor liver transplant patients compared with deceased donor liver transplant patients...- Pharmacokinetics of tacrolimus in living donor liver transplant and deceased donor liver transplant recipientsAshok Jain
Department of Surgery, Division of Solid Organ Transplant, University of Rochester Medical Center, Rochester, NY, USA
Transplantation 85:554-60. 2008..AIM.: The aim of the present study is to compare the dosage, concentration and pharmacokinetics parameters of tacrolimus between LDLT and deceased donor liver transplant (DDLT) recipients... - Stratifying risk of biliary complications in adult living donor liver transplantation by magnetic resonance cholangiographyRandeep Kashyap
Division of Transplantation, Department of Surgery, University of Rochester Medical Center, Rochester, NY 14642 8410, USA
Transplantation 85:1569-72. 2008..Accurate preoperative assessment of biliary anatomy in live donor hepatectomy may be helpful to assess the suitability of a graft and to stratify risk of biliary complications... - Potential immunological advantage of intravenous mycophenolate mofetil with tacrolimus and steroids in primary deceased donor liver transplantation and live donor liver transplantation without antibody inductionAshokkumar Jain
Department of Surgery, Division of Solid Organ Transplantation, University of Rochester Medical Center, Rochester, NY 14642, USA
Liver Transpl 14:202-9. 2008..All patients responded to steroid therapy. None of the patients required any antibody preparation. In conclusion, IV MMF with tacrolimus and steroids is useful and required antirejection therapy in 6.1% of liver transplant recipients... 
Is left lobe adult-to-adult living donor liver transplantation ready for widespread use? The US experience (1998-2010)Reza F Saidi
Division of Organ Transplantation, Department of Surgery, University of Massachusetts Medical School, Worcester, MA 01655, USA
HPB (Oxford) 14:455-60. 2012..Living donor liver transplantation (LDLT) is an accepted treatment for patients with end-stage liver disease. To minimize risk to the donor, left lobe (LL) LDLT may be an ideal option in adult LDLT...- Impact of center volume on outcomes of increased-risk liver transplantsDeepak K Ozhathil
Solid Organ Transplantation, Surgical Outcomes Analysis and Research SOAR, Department of Surgery, University of Massachusetts Medical School, Worcester, MA 01655, USA
Liver Transpl 17:1191-9. 2011..A greater understanding of the outcomes of transplantation with high-DRI livers may improve their utilization, the postoperative outcomes, and future allocation practices... - Should trichrome stain be used on all post-liver transplant biopsies with hepatitis C virus infection to estimate the fibrosis score?David Tretheway
Department of Pathology and Laboratory Medicine, Department of Surgery, Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Liver Transpl 14:695-700. 2008..The fibrosis stage may be an indicator of significant liver damage in these patients. Accuracy of its determination may be most easily facilitated by employment of a connective tissue stain... - High mortality in orthotopic liver transplant recipients who require hemodialysisMartin S Zand
Division of Nephrology, University of Rochester Medical Center, Rochester, NY 14642, USA
Clin Transplant 25:213-21. 2011..5, and male gender. We conclude that renal failure requiring hemodialysis post liver transplant, irrespective of pre-transplant dialysis status, is a profound risk factor for death in liver transplant recipients... - Outcomes in partial liver transplantation: deceased donor split-liver vs. live donor liver transplantationReza F Saidi
Division of Organ Transplantation, Department of Surgery, University of Massachusetts Medical School, Worcester, USA
HPB (Oxford) 13:797-801. 2011..Organ shortage has resulted in greater emphasis on partial liver transplantation (PLT) as an alternative to whole-organ liver transplantation... - Characterization of CD4, CD8, CD56 positive lymphocytes and C4d deposits to distinguish acute cellular rejection from recurrent hepatitis C in post-liver transplant biopsiesAshok Jain
Department of Surgery, Division of Transplantation, University of Rochester Medical Center, Rochester, NY 14642, USA
Clin Transplant 20:624-33. 2006..Hepatitis C viral recurrence in liver allograft is almost universal, which is often difficult to distinguish from acute cellular rejection (ACR)... - Pharmacokinetics of mycophenolic acid in liver transplant patients after intravenous and oral administration of mycophenolate mofetilAshok Jain
Department of Surgery, Division of Transplantation, University of Rochester Medical Center, Rochester, NY 14642, USA
Liver Transpl 13:791-6. 2007..In conclusion, during the early postoperative period, LTx recipients have MPA exposure with oral MMF of less than half that of IV MMF. Use of IV MMF immediately post-LTx may provide an immunological advantage... - Intravenous mycophenolate mofetil with low-dose oral tacrolimus and steroid induction for live donor liver transplantationAshok Jain
Department of Surgery, Division of Transplantation, University of Rochester Medical Center, Box SURG, Rochester, NY 14642, USA
Exp Clin Transplant 3:361-5. 2005..Previously published studies have used oral formulations of MMF. In this study, we sought to examine survival, rejection, and nephrotoxicity rates using IV MMF in live donor liver transplantation (LDLT)... - HCV antibody quantitative levels in liver transplant patients: do they have any relevance in clinical practice?Ashok Jain
University of Rochester Medical Center, Division of Transplantation, Department of Surgery, Rochester, NY 14642, USA
Exp Clin Transplant 4:475-80. 2006.... - Survival after liver transplantation using hepatitis C virus-positive donor allografts: case-controlled analysis of the UNOS databaseAndrew T Burr
Department of Surgery, Surgical Outcomes Analysis and Research, University of Massachusetts Medical School, Worcester, MA 01655, USA
World J Surg 35:1590-5. 2011..We aimed to examine if the use of a HCV+ liver allograft affects patient and graft survivals compared to HCV- donor allografts in a case-controlled analysis of the united network for organ sharing (UNOS) database... - Minimizing morbidity of organ donation: analysis of factors for perioperative complications after living-donor nephrectomy in the United StatesSiddharth Patel
Division of Transplantation, Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA
Transplantation 85:561-5. 2008..Wide variability exists in reported donor complications, and associated risk factors are ill defined. Use of administrative data can overcome the bias of single-center studies and identify variables associated with untoward events... - Comparison of right lobe donor hepatectomy with elective right hepatectomy for other causes in New YorkAndrew T Burr
Department of Surgery, Solid Organ Transplantation, Surgical Outcomes Analysis and Research, University of Massachusetts Medical School, 55 Lake Avenue North, S6 432, Worcester, MA 01655, USA
Dig Dis Sci 56:1869-75. 2011..Since there is no live donor registry in the United States, a population-based, unsolicited state-wide analysis has yet to be reported... - Postoperative impact of intraoperative biochemical changes at the completion of parenchymal division in living-donor liver transplantationAshok Jain
Department of Surgery, Division of Transplantation, University of Rochester Medical Center, Rochester, New York 14642, USA
Exp Clin Transplant 4:544-8. 2006.... - University of Wisconsin versus histidine-tryptophan-ketoglutarate for tissue preservation in live-donor liver transplantationAshok Jain
Department of Surgery, Division of Transplantation, University of Rochester Medical Center, Rochester, NY 14642, USA
Exp Clin Transplant 4:451-7. 2006..We therefore sought to examine the hepatic function of live-donor liver transplantation allografts preserved in University of Wisconsin solution as compared with those preserved in histidine-tryptophan- ketoglutarate solution... - Effect of centre volume and high donor risk index on liver allograft survivalDeepak K Ozhathil
Department of Surgery, Surgical Outcomes Analysis and Research, University of Massachusetts Medical School, Worcester, MA, USA
HPB (Oxford) 13:447-53. 2011..Using risk-adjusted models, the aim of the present study was to determine whether a volume-outcome relationship existed among liver transplants at high risk for allograft failure... - Polysubstance abuse in liver transplant patients and its impact on survival outcomeMark Nickels
Department of Psychiatry, University of Rochester Medical Center, Rochester, NY, USA
Exp Clin Transplant 5:680-5. 2007..It is important to understand posttransplant survival outcomes in patients with multiple substance abuse and pretransplant factors that predict relapse... - Pediatric liver and kidney transplantation with allografts from DCD donors: A review of UNOS dataPeter Abt
Department of Surgery, Solid Organ Transplantation and Hepatobiliary Surgery Division, University of Rochester Medical Center, Rochester, NY 14642 8410, USA
Transplantation 82:1708-11. 2006..While there is increasing acceptance of these grafts in adults, transplant centers appear reluctant to use these grafts in the pediatric population... - Modification of a biventricular assist device to facilitate preservative infusion and organ recovery in a nonheart-beating donorRon Angona
Department of Surgery, Division of Cardiothoracic Surgery, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
J Extra Corpor Technol 38:157-60. 2006..This report discusses the technical aspects of this potentially beneficial procedure... - The faltering solid organ donor pool in the United States (2001-2010)Reza F Saidi
Division of Organ Transplantation, Department of Surgery, University of Massachusetts Medical School, 55 Lake Avenue North, S6 426, Worcester, MA 01655, USA
World J Surg 36:2909-13. 2012..Organ shortage is the greatest challenge facing the field of organ transplantation today. Use of more organs of marginal quality has been advocated to address the shortage... - Incidence, risk factors and consequences of portal vein and systemic thromboses in hepatocellular carcinomaGregory C Connolly
Department of Medicine, University of Rochester, Rochester, NY, USA
Thromb Res 122:299-306. 2008..Hepatocellular carcinoma (HCC) is commonly associated with portal vein thrombosis (PVT). Little is known about factors predictive for PVT in patients with HCC or its correlation with systemic venous thromboembolism (VTE)... - Polyclonal rabbit antithymocyte globulin triggers B-cell and plasma cell apoptosis by multiple pathwaysMartin S Zand
Nephrology Unit, University of Rochester Medical Center, Rochester, NY 14642, USA
Transplantation 79:1507-15. 2005..The authors recently demonstrated that rabbit (r) ATG can be used in combination with plasmapheresis to effectively treat antibody-mediated renal allograft rejection. This observation suggested that rATG may have anti-B cell activity... - A renewable source of donor cells for repetitive monitoring of T- and B-cell alloreactivityMartin S Zand
Nephrology Unit, Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA
Am J Transplant 5:76-86. 2005..We conclude that sBc are a renewable source of donor-specific target/stimulator cells for use in repetitive and coordinate assays of B- and T-cell alloreactivity... - Current trends and short-term outcomes of live donor nephrectomy: a population-based analysis of the nationwide inpatient sampleBeth Colombo
Department of Surgery, Surgical Outcomes Analysis and Research, University of Massachusetts Medical School, 55 Lake Avenue North, S6 432, Worcester, MA 01655, USA
World J Surg 34:2985-90. 2010..Recent United Network for Organ Sharing (UNOS) data suggest that live kidney donation is stagnant. Current practices and trends in laparoscopic donor nephrectomy (LDN) among the transplant community remain largely unknown... - Postliver transplantation vascular and biliary surgical anatomyWael E A Saad
Vascular Interventional Radiology Section, Department of Imaging Sciences, University of Rochester Medical Center, Rochester, NY 14618, USA
Tech Vasc Interv Radiol 10:172-90. 2007..With radiologists as the target readers, the chapter focuses on the inflow and outflow connections and does not detail intricate surgical techniques or intraoperative maneuvers, operative stages, or vascular shunting... - Home glucometer monitoring markedly improves diagnosis of post renal transplant diabetes mellitus in renal transplant recipientsAmish Shah
Division of Nephrology, Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
Transplantation 80:775-81. 2005..All diagnoses were made based on prelunch or supper FPG >200 mg/dl. CONCLUSIONS: Overnight FPG are inadequate for diagnosis of PTDM. All renal transplant recipients with impaired FPG should, at minimum, have home FPG testing... - Impact of hepatitis C viral infection in primary cadaveric liver allograft versus primary living-donor allograft in 100 consecutive liver transplant recipients receiving tacrolimusAdel Bozorgzadeh
Department of Surgery, University of Rochester, Rochester, New York 14642, USA
Transplantation 77:1066-70. 2004..Patient survival, graft survival, rate of HCV recurrence, severity of HCV recurrence, graft loss from HCV, and interval for recurrence in CLTx and LLTx were similar... - Hepatic arterial reconstruction in 95 adult right lobe living donor liver transplants: evolution of anastomotic techniqueAmadeo Marcos
Section of Solid Organ Transplantation, Department of Surgery, University of Rochester Strong Hospital, NY, USA
Liver Transpl 9:570-4. 2003..Outcome and the incidence of hepatic artery thrombosis are reported... - TLR-dependent cross talk between human Kupffer cells and NK cellsZhengkun Tu
Department of Surgery, Division of Solid Organ Transplantation and Hepatobiliary Surgery, University of Rochester Medical Center, Rochester, NY 14642, USA
J Exp Med 205:233-44. 2008..Subversion of cellular mechanisms of innate immune response against viruses may be important for hepatotropic viruses (e.g., hepatitis B and C) to develop persistence... - Liver transplantation in sickle cell anemia: a case of acute sickle cell intrahepatic cholestasis and a case of sclerosing cholangitisMatthew M Baichi
Department of Medicine, Digestive and Liver Diseases Unit, University of Rochester, Strong Memorial Hospital, 601 Elmwood Avenue, Box 646, Rochester, NY 14642, USA
Transplantation 80:1630-2. 2005..Liver transplantation did not lead to a successful outcome in either case... - Hypophosphatemia after 95 right-lobe living-donor hepatectomies for liver transplantation is not a significant source of morbidityHenkie P Tan
Thomas E Starzl Transplant Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Transplantation 76:1085-8. 2003..Because hypophosphatemia appears to contribute to increased postoperative complications, routine hyperalimentation with supratherapeutic levels of phosphorus was advocated... - Common iliac artery lying posterior to psoas major identified during kidney transplantationAshok Jain
Transplantation 86:623-4. 2008 - Question of using valganciclovir for cytomegalovirus (CMV) infection prophylaxis in post-liver transplant recipientsAshok Jain
Liver Transpl 12:1020-1; author reply 1022-3. 2006