Adel Bozorgzadeh

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi Survival outcomes in liver transplantation for hepatocellular carcinoma, comparing impact of hepatitis C versus other etiology of cirrhosis
    Adel Bozorgzadeh
    Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA
    Liver Transpl 13:807-13. 2007
  2. doi Pharmacokinetics of mycophenolic acid in live donor liver transplant patients vs deceased donor liver transplant patients
    Ashok Jain
    University of Rochester Medical Center, Department of Surgery, Division of Solid Organ Transplantation, Rochester, NY 14642, USA
    J Clin Pharmacol 48:547-52. 2008
  3. doi Pharmacokinetics of tacrolimus in living donor liver transplant and deceased donor liver transplant recipients
    Ashok Jain
    Department of Surgery, Division of Solid Organ Transplant, University of Rochester Medical Center, Rochester, NY, USA
    Transplantation 85:554-60. 2008
  4. ncbi Stratifying risk of biliary complications in adult living donor liver transplantation by magnetic resonance cholangiography
    Randeep Kashyap
    Division of Transplantation, Department of Surgery, University of Rochester Medical Center, Rochester, NY 14642 8410, USA
    Transplantation 85:1569-72. 2008
  5. doi Potential immunological advantage of intravenous mycophenolate mofetil with tacrolimus and steroids in primary deceased donor liver transplantation and live donor liver transplantation without antibody induction
    Ashokkumar Jain
    Department of Surgery, Division of Solid Organ Transplantation, University of Rochester Medical Center, Rochester, NY 14642, USA
    Liver Transpl 14:202-9. 2008
  6. doi Impact of center volume on outcomes of increased-risk liver transplants
    Deepak K Ozhathil
    Solid Organ Transplantation, Surgical Outcomes Analysis and Research SOAR, Department of Surgery, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Liver Transpl 17:1191-9. 2011
  7. pmc Is left lobe adult-to-adult living donor liver transplantation ready for widespread use? The US experience (1998-2010)
    Reza F Saidi
    Division of Organ Transplantation, Department of Surgery, University of Massachusetts Medical School, Worcester, MA 01655, USA
    HPB (Oxford) 14:455-60. 2012
  8. doi Should trichrome stain be used on all post-liver transplant biopsies with hepatitis C virus infection to estimate the fibrosis score?
    David Tretheway
    Department of Pathology and Laboratory Medicine, Department of Surgery, Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Liver Transpl 14:695-700. 2008
  9. doi High mortality in orthotopic liver transplant recipients who require hemodialysis
    Martin S Zand
    Division of Nephrology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Clin Transplant 25:213-21. 2011
  10. pmc Outcomes in partial liver transplantation: deceased donor split-liver vs. live donor liver transplantation
    Reza F Saidi
    Division of Organ Transplantation, Department of Surgery, University of Massachusetts Medical School, Worcester, USA
    HPB (Oxford) 13:797-801. 2011

Collaborators

Detail Information

Publications37

  1. ncbi Survival outcomes in liver transplantation for hepatocellular carcinoma, comparing impact of hepatitis C versus other etiology of cirrhosis
    Adel Bozorgzadeh
    Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA
    Liver Transpl 13:807-13. 2007
    ..Our results suggest that Milan selection criteria may be too limiting and lose their predictive power when applied to patients without HCV infection...
  2. doi Pharmacokinetics of mycophenolic acid in live donor liver transplant patients vs deceased donor liver transplant patients
    Ashok Jain
    University of Rochester Medical Center, Department of Surgery, Division of Solid Organ Transplantation, Rochester, NY 14642, USA
    J Clin Pharmacol 48:547-52. 2008
    ..These observations point to the need to use a lower dosage (approximately 30%) of mycophenolate mofetil in live donor liver transplant patients compared with deceased donor liver transplant patients...
  3. doi Pharmacokinetics of tacrolimus in living donor liver transplant and deceased donor liver transplant recipients
    Ashok Jain
    Department of Surgery, Division of Solid Organ Transplant, University of Rochester Medical Center, Rochester, NY, USA
    Transplantation 85:554-60. 2008
    ..AIM.: The aim of the present study is to compare the dosage, concentration and pharmacokinetics parameters of tacrolimus between LDLT and deceased donor liver transplant (DDLT) recipients...
  4. ncbi Stratifying risk of biliary complications in adult living donor liver transplantation by magnetic resonance cholangiography
    Randeep Kashyap
    Division of Transplantation, Department of Surgery, University of Rochester Medical Center, Rochester, NY 14642 8410, USA
    Transplantation 85:1569-72. 2008
    ..Accurate preoperative assessment of biliary anatomy in live donor hepatectomy may be helpful to assess the suitability of a graft and to stratify risk of biliary complications...
  5. doi Potential immunological advantage of intravenous mycophenolate mofetil with tacrolimus and steroids in primary deceased donor liver transplantation and live donor liver transplantation without antibody induction
    Ashokkumar Jain
    Department of Surgery, Division of Solid Organ Transplantation, University of Rochester Medical Center, Rochester, NY 14642, USA
    Liver Transpl 14:202-9. 2008
    ..All patients responded to steroid therapy. None of the patients required any antibody preparation. In conclusion, IV MMF with tacrolimus and steroids is useful and required antirejection therapy in 6.1% of liver transplant recipients...
  6. doi Impact of center volume on outcomes of increased-risk liver transplants
    Deepak K Ozhathil
    Solid Organ Transplantation, Surgical Outcomes Analysis and Research SOAR, Department of Surgery, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Liver Transpl 17:1191-9. 2011
    ..A greater understanding of the outcomes of transplantation with high-DRI livers may improve their utilization, the postoperative outcomes, and future allocation practices...
  7. pmc Is left lobe adult-to-adult living donor liver transplantation ready for widespread use? The US experience (1998-2010)
    Reza F Saidi
    Division of Organ Transplantation, Department of Surgery, University of Massachusetts Medical School, Worcester, MA 01655, USA
    HPB (Oxford) 14:455-60. 2012
    ..Living donor liver transplantation (LDLT) is an accepted treatment for patients with end-stage liver disease. To minimize risk to the donor, left lobe (LL) LDLT may be an ideal option in adult LDLT...
  8. doi Should trichrome stain be used on all post-liver transplant biopsies with hepatitis C virus infection to estimate the fibrosis score?
    David Tretheway
    Department of Pathology and Laboratory Medicine, Department of Surgery, Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Liver Transpl 14:695-700. 2008
    ..The fibrosis stage may be an indicator of significant liver damage in these patients. Accuracy of its determination may be most easily facilitated by employment of a connective tissue stain...
  9. doi High mortality in orthotopic liver transplant recipients who require hemodialysis
    Martin S Zand
    Division of Nephrology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Clin Transplant 25:213-21. 2011
    ..5, and male gender. We conclude that renal failure requiring hemodialysis post liver transplant, irrespective of pre-transplant dialysis status, is a profound risk factor for death in liver transplant recipients...
  10. pmc Outcomes in partial liver transplantation: deceased donor split-liver vs. live donor liver transplantation
    Reza F Saidi
    Division of Organ Transplantation, Department of Surgery, University of Massachusetts Medical School, Worcester, USA
    HPB (Oxford) 13:797-801. 2011
    ..Organ shortage has resulted in greater emphasis on partial liver transplantation (PLT) as an alternative to whole-organ liver transplantation...
  11. ncbi Pharmacokinetics of mycophenolic acid in liver transplant patients after intravenous and oral administration of mycophenolate mofetil
    Ashok Jain
    Department of Surgery, Division of Transplantation, University of Rochester Medical Center, Rochester, NY 14642, USA
    Liver Transpl 13:791-6. 2007
    ..In conclusion, during the early postoperative period, LTx recipients have MPA exposure with oral MMF of less than half that of IV MMF. Use of IV MMF immediately post-LTx may provide an immunological advantage...
  12. ncbi Characterization of CD4, CD8, CD56 positive lymphocytes and C4d deposits to distinguish acute cellular rejection from recurrent hepatitis C in post-liver transplant biopsies
    Ashok Jain
    Department of Surgery, Division of Transplantation, University of Rochester Medical Center, Rochester, NY 14642, USA
    Clin Transplant 20:624-33. 2006
    ..Hepatitis C viral recurrence in liver allograft is almost universal, which is often difficult to distinguish from acute cellular rejection (ACR)...
  13. doi The faltering solid organ donor pool in the United States (2001-2010)
    Reza F Saidi
    Division of Organ Transplantation, Department of Surgery, University of Massachusetts Medical School, 55 Lake Avenue North, S6 426, Worcester, MA 01655, USA
    World J Surg 36:2909-13. 2012
    ..Organ shortage is the greatest challenge facing the field of organ transplantation today. Use of more organs of marginal quality has been advocated to address the shortage...
  14. ncbi HCV antibody quantitative levels in liver transplant patients: do they have any relevance in clinical practice?
    Ashok Jain
    University of Rochester Medical Center, Division of Transplantation, Department of Surgery, Rochester, NY 14642, USA
    Exp Clin Transplant 4:475-80. 2006
    ....
  15. ncbi Intravenous mycophenolate mofetil with low-dose oral tacrolimus and steroid induction for live donor liver transplantation
    Ashok Jain
    Department of Surgery, Division of Transplantation, University of Rochester Medical Center, Box SURG, Rochester, NY 14642, USA
    Exp Clin Transplant 3:361-5. 2005
    ..Previously published studies have used oral formulations of MMF. In this study, we sought to examine survival, rejection, and nephrotoxicity rates using IV MMF in live donor liver transplantation (LDLT)...
  16. doi Survival after liver transplantation using hepatitis C virus-positive donor allografts: case-controlled analysis of the UNOS database
    Andrew T Burr
    Department of Surgery, Surgical Outcomes Analysis and Research, University of Massachusetts Medical School, Worcester, MA 01655, USA
    World J Surg 35:1590-5. 2011
    ..We aimed to examine if the use of a HCV+ liver allograft affects patient and graft survivals compared to HCV- donor allografts in a case-controlled analysis of the united network for organ sharing (UNOS) database...
  17. ncbi Postoperative impact of intraoperative biochemical changes at the completion of parenchymal division in living-donor liver transplantation
    Ashok Jain
    Department of Surgery, Division of Transplantation, University of Rochester Medical Center, Rochester, New York 14642, USA
    Exp Clin Transplant 4:544-8. 2006
    ....
  18. doi Minimizing morbidity of organ donation: analysis of factors for perioperative complications after living-donor nephrectomy in the United States
    Siddharth Patel
    Division of Transplantation, Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA
    Transplantation 85:561-5. 2008
    ..Wide variability exists in reported donor complications, and associated risk factors are ill defined. Use of administrative data can overcome the bias of single-center studies and identify variables associated with untoward events...
  19. ncbi University of Wisconsin versus histidine-tryptophan-ketoglutarate for tissue preservation in live-donor liver transplantation
    Ashok Jain
    Department of Surgery, Division of Transplantation, University of Rochester Medical Center, Rochester, NY 14642, USA
    Exp Clin Transplant 4:451-7. 2006
    ..We therefore sought to examine the hepatic function of live-donor liver transplantation allografts preserved in University of Wisconsin solution as compared with those preserved in histidine-tryptophan- ketoglutarate solution...
  20. doi Comparison of right lobe donor hepatectomy with elective right hepatectomy for other causes in New York
    Andrew T Burr
    Department of Surgery, Solid Organ Transplantation, Surgical Outcomes Analysis and Research, University of Massachusetts Medical School, 55 Lake Avenue North, S6 432, Worcester, MA 01655, USA
    Dig Dis Sci 56:1869-75. 2011
    ..Since there is no live donor registry in the United States, a population-based, unsolicited state-wide analysis has yet to be reported...
  21. pmc Effect of centre volume and high donor risk index on liver allograft survival
    Deepak K Ozhathil
    Department of Surgery, Surgical Outcomes Analysis and Research, University of Massachusetts Medical School, Worcester, MA, USA
    HPB (Oxford) 13:447-53. 2011
    ..Using risk-adjusted models, the aim of the present study was to determine whether a volume-outcome relationship existed among liver transplants at high risk for allograft failure...
  22. ncbi Pediatric liver and kidney transplantation with allografts from DCD donors: A review of UNOS data
    Peter Abt
    Department of Surgery, Solid Organ Transplantation and Hepatobiliary Surgery Division, University of Rochester Medical Center, Rochester, NY 14642 8410, USA
    Transplantation 82:1708-11. 2006
    ..While there is increasing acceptance of these grafts in adults, transplant centers appear reluctant to use these grafts in the pediatric population...
  23. ncbi Polysubstance abuse in liver transplant patients and its impact on survival outcome
    Mark Nickels
    Department of Psychiatry, University of Rochester Medical Center, Rochester, NY, USA
    Exp Clin Transplant 5:680-5. 2007
    ..It is important to understand posttransplant survival outcomes in patients with multiple substance abuse and pretransplant factors that predict relapse...
  24. ncbi Modification of a biventricular assist device to facilitate preservative infusion and organ recovery in a nonheart-beating donor
    Ron Angona
    Department of Surgery, Division of Cardiothoracic Surgery, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    J Extra Corpor Technol 38:157-60. 2006
    ..This report discusses the technical aspects of this potentially beneficial procedure...
  25. pmc Incidence, risk factors and consequences of portal vein and systemic thromboses in hepatocellular carcinoma
    Gregory C Connolly
    Department of Medicine, University of Rochester, Rochester, NY, USA
    Thromb Res 122:299-306. 2008
    ..Hepatocellular carcinoma (HCC) is commonly associated with portal vein thrombosis (PVT). Little is known about factors predictive for PVT in patients with HCC or its correlation with systemic venous thromboembolism (VTE)...
  26. ncbi Polyclonal rabbit antithymocyte globulin triggers B-cell and plasma cell apoptosis by multiple pathways
    Martin S Zand
    Nephrology Unit, University of Rochester Medical Center, Rochester, NY 14642, USA
    Transplantation 79:1507-15. 2005
    ..The authors recently demonstrated that rabbit (r) ATG can be used in combination with plasmapheresis to effectively treat antibody-mediated renal allograft rejection. This observation suggested that rATG may have anti-B cell activity...
  27. ncbi A renewable source of donor cells for repetitive monitoring of T- and B-cell alloreactivity
    Martin S Zand
    Nephrology Unit, Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA
    Am J Transplant 5:76-86. 2005
    ..We conclude that sBc are a renewable source of donor-specific target/stimulator cells for use in repetitive and coordinate assays of B- and T-cell alloreactivity...
  28. doi Current trends and short-term outcomes of live donor nephrectomy: a population-based analysis of the nationwide inpatient sample
    Beth Colombo
    Department of Surgery, Surgical Outcomes Analysis and Research, University of Massachusetts Medical School, 55 Lake Avenue North, S6 432, Worcester, MA 01655, USA
    World J Surg 34:2985-90. 2010
    ..Recent United Network for Organ Sharing (UNOS) data suggest that live kidney donation is stagnant. Current practices and trends in laparoscopic donor nephrectomy (LDN) among the transplant community remain largely unknown...
  29. ncbi Postliver transplantation vascular and biliary surgical anatomy
    Wael E A Saad
    Vascular Interventional Radiology Section, Department of Imaging Sciences, University of Rochester Medical Center, Rochester, NY 14618, USA
    Tech Vasc Interv Radiol 10:172-90. 2007
    ..With radiologists as the target readers, the chapter focuses on the inflow and outflow connections and does not detail intricate surgical techniques or intraoperative maneuvers, operative stages, or vascular shunting...
  30. ncbi Home glucometer monitoring markedly improves diagnosis of post renal transplant diabetes mellitus in renal transplant recipients
    Amish Shah
    Division of Nephrology, Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Transplantation 80:775-81. 2005
    ..Most patients are monitored for PTDM by 12-hour FPG levels drawn for clinic visits. In contrast, we describe the diagnosis of PTDM by home glucometer monitoring..
  31. ncbi Impact of hepatitis C viral infection in primary cadaveric liver allograft versus primary living-donor allograft in 100 consecutive liver transplant recipients receiving tacrolimus
    Adel Bozorgzadeh
    Department of Surgery, University of Rochester, Rochester, New York 14642, USA
    Transplantation 77:1066-70. 2004
    ..This study examines the survival outcome and HCV recurrence in CLTx versus LLTx performed at a single institution...
  32. ncbi Hepatic arterial reconstruction in 95 adult right lobe living donor liver transplants: evolution of anastomotic technique
    Amadeo Marcos
    Section of Solid Organ Transplantation, Department of Surgery, University of Rochester Strong Hospital, NY, USA
    Liver Transpl 9:570-4. 2003
    ..Outcome and the incidence of hepatic artery thrombosis are reported...
  33. pmc TLR-dependent cross talk between human Kupffer cells and NK cells
    Zhengkun Tu
    Department of Surgery, Division of Solid Organ Transplantation and Hepatobiliary Surgery, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Exp Med 205:233-44. 2008
    ..Subversion of cellular mechanisms of innate immune response against viruses may be important for hepatotropic viruses (e.g., hepatitis B and C) to develop persistence...
  34. ncbi Liver transplantation in sickle cell anemia: a case of acute sickle cell intrahepatic cholestasis and a case of sclerosing cholangitis
    Matthew M Baichi
    Department of Medicine, Digestive and Liver Diseases Unit, University of Rochester, Strong Memorial Hospital, 601 Elmwood Avenue, Box 646, Rochester, NY 14642, USA
    Transplantation 80:1630-2. 2005
    ..Liver transplantation did not lead to a successful outcome in either case...
  35. ncbi Hypophosphatemia after 95 right-lobe living-donor hepatectomies for liver transplantation is not a significant source of morbidity
    Henkie P Tan
    Thomas E Starzl Transplant Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Transplantation 76:1085-8. 2003
    ..Because hypophosphatemia appears to contribute to increased postoperative complications, routine hyperalimentation with supratherapeutic levels of phosphorus was advocated...
  36. doi Common iliac artery lying posterior to psoas major identified during kidney transplantation
    Ashok Jain
    Transplantation 86:623-4. 2008
  37. ncbi Question of using valganciclovir for cytomegalovirus (CMV) infection prophylaxis in post-liver transplant recipients
    Ashok Jain
    Liver Transpl 12:1020-1; author reply 1022-3. 2006