Research Topics
| Andrew J BoyleSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Quantitative automated assessment of myocardial perfusion at cardiac catheterizationAndrew J Boyle
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Cardiol 102:980-7. 2008..Further studies to assess the prognostic value of this technique are warranted...
Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagyAndrew J Boyle
Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, CA 94143, United States
Exp Gerontol 46:549-59. 2011..In conclusion, we describe the functional, structural and genetic changes in murine hearts as they first develop cardiomyopathy of aging...- Mesenchymal stem cell therapy for cardiac repairAndrew J Boyle
Cardiology Division, Department of Medicine, University of California, San Francisco, CA, USA
Methods Mol Biol 660:65-84. 2010..This review discusses the mechanism of action of MSC therapy and summarizes the current literature in the field... - Myocardial production and release of MCP-1 and SDF-1 following myocardial infarction: differences between mice and manAndrew J Boyle
Department of Medicine, Division of Cardiology, University of California San Francisco, USA
J Transl Med 9:150. 2011..It remains unknown if they are produced by, and released from, the heart in order to attract stem cells to repair the damaged myocardium... - Early improvement in cardiac tissue perfusion due to mesenchymal stem cellsKarl H Schuleri
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am J Physiol Heart Circ Physiol 294:H2002-11. 2008..Cardiac MRI-based measures of blood flow may be a useful tool to predict a successful myocardial regenerative process after MSC treatment... - Evidence of diminished coronary flow in pulmonary hypertension: explaining angina pectoris in this patient group?Juha W Koskenvuo
Division of Cardiology, Department of Medicine, University of California, San Francisco, USA
Clin Physiol Funct Imaging 31:477-84. 2011..The role of pulmonary artery dilatation, septal wall motion abnormality, cardiac output or diastolic blood pressure in determining coronary blood flow (CBF) during PH was determined... - Treatment of pulmonary arterial hypertension with circulating angiogenic cellsRachel Mirsky
Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
Am J Physiol Lung Cell Mol Physiol 301:L12-9. 2011..Future studies should be geared toward either earlier therapeutic time points with varying doses of unmodified CACs or genetically modified cells as a means of delivery of factors to the pulmonary arterial circulation... - Timing of bone marrow cell therapy is more important than repeated injections after myocardial infarctionYan Zhang
Division of Cardiology, Department of Medicine, University of California San Francisco, CA 94143 0103, USA
Cardiovasc Pathol 20:204-12. 2011..Bone marrow cell treatment has been proposed as a therapy for myocardial infarction, but the optimal timing and number of injections remain unknown... 
Multimodality noninvasive imaging demonstrates in vivo cardiac regeneration after mesenchymal stem cell therapyLuciano C Amado
Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Am Coll Cardiol 48:2116-24. 2006....- The adult Göttingen minipig as a model for chronic heart failure after myocardial infarction: focus on cardiovascular imaging and regenerative therapiesKarl H Schuleri
Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA
Comp Med 58:568-79. 2008..New heart failure therapies and devices can be tested preclinically in this adult animal model of chronic heart failure... - Fractionation of mouse bone-marrow cells limits functional efficacy in non-reperfused mouse model of acute myocardial infarctionJuha W Koskenvuo
Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
Ann Med 44:829-35. 2012.... - Multivessel coronary artery disease predicts mortality, length of stay, and pressor requirements after liver transplantationCelina M Yong
Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA
Liver Transpl 16:1242-8. 2010..This study provides preliminary evidence showing that there may be significant prognostic value in coronary angiography as a part of the pretransplant workup... - Injection of bone marrow cell extract into infarcted hearts results in functional improvement comparable to intact cell therapyYerem Yeghiazarians
Department of Medicine, University of California San Francisco, 94143 0103, USA
Mol Ther 17:1250-6. 2009..Intact cells are not necessary and death of implanted cells may be a major component of the benefit... - The aging heart and post-infarction left ventricular remodelingHenry Shih
Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, California 94143, USA
J Am Coll Cardiol 57:9-17. 2011..We review the cellular and molecular aspects of post-infarction remodeling in the aged heart, and relate them to the clinical problem of post-infarction remodeling in elderly patients... - Assessment of a novel angiographic image stabilization system for percutaneous coronary interventionAndrew J Boyle
Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
J Interv Cardiol 20:153-7. 2007..We tested a novel system to stabilize angiographic images at the region of interest in order to assist during PCI... - Sterile radial artery granuloma after transradial procedures: a unique and avoidable complicationChristian Zellner
Department of Medicine, University of California, San Francisco, CA, USA
Catheter Cardiovasc Interv 76:673-6. 2010..2010 Wiley-Liss, Inc... - Sterile radial artery granuloma after transradial cardiac catheterizationChristian Zellner
Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA
Cardiovasc Revasc Med 12:187-9. 2011..The clinical presentation was suggestive of an infected pseudoaneurysm. Awareness of this entity may help clinicians avoid unnecessary surgical procedures, as these granulomata are transient self-limiting reactions... - Renal and hepatic function improve in advanced heart failure patients during continuous-flow support with the HeartMate II left ventricular assist deviceStuart D Russell
Johns Hopkins Hospital, 600 N Wolfe Street, Baltimore, MD 21287, USA
Circulation 120:2352-7. 2009..The effects of continuous blood flow and reduced pulsatility on major organ function have not been studied in detail... - A comparison of echocardiography to invasive measurement in the evaluation of pulmonary arterial hypertension in a rat modelJuha W Koskenvuo
Division of Cardiology, Department of Medicine, University of California, 505 Parnassus Avenue, Box 0103, San Francisco, CA 94143, USA
Int J Cardiovasc Imaging 26:509-18. 2010..These non-invasive parameters may be used to replace invasive measurements in detecting successful disease induction and to complement invasive data in the evaluation of PAH severity in a rat model... - Cardiac Stem Cell Therapy. Need for Optimization of Efficacy and Safety MonitoringPeter Oettgen
Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA
Circulation 114:353-8. 2006 - CD45-positive cells are not an essential component in cardiosphere formationJianqin Ye
Department of Medicine, Division of Cardiology, University of California, San Francisco, San Francisco, CA, USA
Cell Tissue Res 351:201-5. 2013..0001). Purified CD45(+) cells from CS-forming cells did not form CSs in culture. Thus, BM-derived CD45(+) cells including BM progenitors are neither necessary nor sufficient for CS formation... - Safety of cardiac catheterization in patients with end-stage liver disease awaiting liver transplantationMadan Sharma
Division of Cardiology, University of California, San Francisco, San Francisco, California, USA corrected
Am J Cardiol 103:742-6. 2009..In conclusion, despite severe coagulopathy, left-sided cardiac catheterization may be performed safely in this patient population, with correction of coagulopathy and meticulous attention to procedural technique... - Left ventricular remodeling after myocardial infarction: characterization of a swine model on beta-blocker therapyFranca S Angeli
Division of Cardiology, Department of Medicine, University of California, San Francisco, California, USA
Comp Med 59:272-9. 2009..These findings suggest a dynamic pattern of remodeling over time in a closed-chest ischemia-reperfusion swine model of acute MI on beta-blocker therapy and may guide future studies... - Clinical outcomes for continuous-flow left ventricular assist device patients stratified by pre-operative INTERMACS classificationAndrew J Boyle
Division of Cardiology, Aurora St Luke s Medical Center, 2801 West Kinnickinnic River Parkway, Milwaukee, WI 53215, USA
J Heart Lung Transplant 30:402-7. 2011..We use the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) to stratify patients with continuous-flow devices and assess outcomes in less severe, but functionally impaired, heart failure patients... - Catheter-induced coronary artery dissection: risk factors, prevention and managementAndrew J Boyle
Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Invasive Cardiol 18:500-3. 2006..We discuss these risk factors and utilize them to propose methods to prevent dissections. Management options of coronary artery dissection are also discussed... - Is it time to burst the "balloon" for high-risk patients?Sukesh C Burjonroppa
Cardiology Division, Heart and Vascular Center, UCSF, San Francisco, CA 94143, USA
J Invasive Cardiol 19:347-8. 2007 - Coronary air embolism: a case report and review of the literatureJoud Dib
Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Catheter Cardiovasc Interv 68:897-900. 2006..A case report of air embolism and methods to prevent this complication from occurring are presented along with various management techniques... - Topical nitroglycerin and lidocaine locally vasodilate the radial artery without affecting systemic blood pressure: a dose-finding phase I studyDavid T Majure
Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, CA 94143, USA
J Crit Care 27:532.e9-13. 2012..We performed this study to determine if topical nitroglycerin and/or nitroglycerin plus topical lidocaine increases RAD without affecting systemic blood pressure... - Are ventricular assist devices underutilized?Andrew J Boyle
Division of Cardiology, Aurora St Luke s Medical Center, Milwaukee, Wisconsin 53215, USA
J Card Surg 25:421-4. 2010.... - Low thromboembolism and pump thrombosis with the HeartMate II left ventricular assist device: analysis of outpatient anti-coagulationAndrew J Boyle
Division of Cardiology, University of Minnesota, Minneapolis, Minnesota 55455, USA
J Heart Lung Transplant 28:881-7. 2009..We evaluated the risk of thromboembolism and hemorrhage related to the degree of anti-coagulation as reflected by the international normalized ratio (INR)... - Factor Xa inhibitors in acute coronary syndromes and venous thromboembolismCelina M Yong
Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, CA 94143, USA
Curr Vasc Pharmacol 8:5-11. 2010..In this review, we examine the key recent studies on efficacy and safety of FXa inhibitors in ACS and VTE management... - Is stem cell therapy ready for patients? Stem Cell Therapy for Cardiac Repair. Ready for the Next Step Andrew J Boyle
Department of Medicine, Division of Cardiology, Institute for Cell Engineering, and Specialized Center for Cell Based Therapy, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Circulation 114:339-52. 2006 - Additive effects of endothelial progenitor cells combined with ACE inhibition and beta-blockade on left ventricular function following acute myocardial infarctionAndrew J Boyle
University of Melbourne, Department of Medicine, St Vincent s Hospital, Fitzroy, Victoria, 3065, Australia
J Renin Angiotensin Aldosterone Syst 6:33-7. 2005..Clinical trials using stem cell therapy in conjunction with standard medical treatment are warranted... - Intra-coronary high-dose CD34+ stem cells in patients with chronic ischemic heart disease: a 12-month follow-upAndrew J Boyle
Department of Medicine, University of Melbourne, St Vincent s Hospital, Princes St, Fitzroy 3065, Victoria, Australia
Int J Cardiol 109:21-7. 2006..These results demonstrate the feasibility of G-CSF mobilization, leukapheresis and intracoronary transfer of CD34+ stem cells in patients with CIHD, but longer-term studies are required to ensure that this protocol is safe and effective... - Inhibition of protein kinase C reduces left ventricular fibrosis and dysfunction following myocardial infarctionAndrew J Boyle
Department of Medicine, St Vincent s Hospital, University of Melbourne, Melbourne, Princes Street, Fitzroy 3065, Vic, Australia
J Mol Cell Cardiol 39:213-21. 2005..PKC-inhibition with ruboxistaurin led to attenuation in both the pathological fibrosis and impaired cardiac function that follow experimental MI, suggesting a possible role for this agent in preventing post-infarction heart failure...