Andrew J Boyle

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi Quantitative automated assessment of myocardial perfusion at cardiac catheterization
    Andrew J Boyle
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 102:980-7. 2008
  2. pmc Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy
    Andrew J Boyle
    Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, CA 94143, United States
    Exp Gerontol 46:549-59. 2011
  3. pmc Myocardial production and release of MCP-1 and SDF-1 following myocardial infarction: differences between mice and man
    Andrew J Boyle
    Department of Medicine, Division of Cardiology, University of California San Francisco, USA
    J Transl Med 9:150. 2011
  4. doi Mesenchymal stem cell therapy for cardiac repair
    Andrew J Boyle
    Cardiology Division, Department of Medicine, University of California, San Francisco, CA, USA
    Methods Mol Biol 660:65-84. 2010
  5. doi Fractionation of mouse bone-marrow cells limits functional efficacy in non-reperfused mouse model of acute myocardial infarction
    Juha W Koskenvuo
    Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
    Ann Med 44:829-35. 2012
  6. doi Early improvement in cardiac tissue perfusion due to mesenchymal stem cells
    Karl H Schuleri
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Physiol Heart Circ Physiol 294:H2002-11. 2008
  7. doi Evidence of diminished coronary flow in pulmonary hypertension: explaining angina pectoris in this patient group?
    Juha W Koskenvuo
    Division of Cardiology, Department of Medicine, University of California, San Francisco, USA
    Clin Physiol Funct Imaging 31:477-84. 2011
  8. doi Treatment of pulmonary arterial hypertension with circulating angiogenic cells
    Rachel Mirsky
    Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
    Am J Physiol Lung Cell Mol Physiol 301:L12-9. 2011
  9. doi Timing of bone marrow cell therapy is more important than repeated injections after myocardial infarction
    Yan Zhang
    Division of Cardiology, Department of Medicine, University of California San Francisco, CA 94143 0103, USA
    Cardiovasc Pathol 20:204-12. 2011
  10. ncbi Multimodality noninvasive imaging demonstrates in vivo cardiac regeneration after mesenchymal stem cell therapy
    Luciano C Amado
    Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Am Coll Cardiol 48:2116-24. 2006

Collaborators

Detail Information

Publications36

  1. doi Quantitative automated assessment of myocardial perfusion at cardiac catheterization
    Andrew J Boyle
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 102:980-7. 2008
    ..Further studies to assess the prognostic value of this technique are warranted...
  2. pmc Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy
    Andrew J Boyle
    Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, CA 94143, United States
    Exp Gerontol 46:549-59. 2011
    ..In conclusion, we describe the functional, structural and genetic changes in murine hearts as they first develop cardiomyopathy of aging...
  3. pmc Myocardial production and release of MCP-1 and SDF-1 following myocardial infarction: differences between mice and man
    Andrew J Boyle
    Department of Medicine, Division of Cardiology, University of California San Francisco, USA
    J Transl Med 9:150. 2011
    ..It remains unknown if they are produced by, and released from, the heart in order to attract stem cells to repair the damaged myocardium...
  4. doi Mesenchymal stem cell therapy for cardiac repair
    Andrew J Boyle
    Cardiology Division, Department of Medicine, University of California, San Francisco, CA, USA
    Methods Mol Biol 660:65-84. 2010
    ..This review discusses the mechanism of action of MSC therapy and summarizes the current literature in the field...
  5. doi Fractionation of mouse bone-marrow cells limits functional efficacy in non-reperfused mouse model of acute myocardial infarction
    Juha W Koskenvuo
    Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
    Ann Med 44:829-35. 2012
    ....
  6. doi Early improvement in cardiac tissue perfusion due to mesenchymal stem cells
    Karl H Schuleri
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Physiol Heart Circ Physiol 294:H2002-11. 2008
    ..Cardiac MRI-based measures of blood flow may be a useful tool to predict a successful myocardial regenerative process after MSC treatment...
  7. doi Evidence of diminished coronary flow in pulmonary hypertension: explaining angina pectoris in this patient group?
    Juha W Koskenvuo
    Division of Cardiology, Department of Medicine, University of California, San Francisco, USA
    Clin Physiol Funct Imaging 31:477-84. 2011
    ..The role of pulmonary artery dilatation, septal wall motion abnormality, cardiac output or diastolic blood pressure in determining coronary blood flow (CBF) during PH was determined...
  8. doi Treatment of pulmonary arterial hypertension with circulating angiogenic cells
    Rachel Mirsky
    Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
    Am J Physiol Lung Cell Mol Physiol 301:L12-9. 2011
    ..Future studies should be geared toward either earlier therapeutic time points with varying doses of unmodified CACs or genetically modified cells as a means of delivery of factors to the pulmonary arterial circulation...
  9. doi Timing of bone marrow cell therapy is more important than repeated injections after myocardial infarction
    Yan Zhang
    Division of Cardiology, Department of Medicine, University of California San Francisco, CA 94143 0103, USA
    Cardiovasc Pathol 20:204-12. 2011
    ..Bone marrow cell treatment has been proposed as a therapy for myocardial infarction, but the optimal timing and number of injections remain unknown...
  10. ncbi Multimodality noninvasive imaging demonstrates in vivo cardiac regeneration after mesenchymal stem cell therapy
    Luciano C Amado
    Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Am Coll Cardiol 48:2116-24. 2006
    ..The purpose of this study was to test the hypothesis, with noninvasive multimodality imaging, that allogeneic mesenchymal stem cells (MSCs) produce and/or stimulate active cardiac regeneration in vivo after myocardial infarction (MI)...
  11. pmc The adult Göttingen minipig as a model for chronic heart failure after myocardial infarction: focus on cardiovascular imaging and regenerative therapies
    Karl H Schuleri
    Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA
    Comp Med 58:568-79. 2008
    ..New heart failure therapies and devices can be tested preclinically in this adult animal model of chronic heart failure...
  12. doi Multivessel coronary artery disease predicts mortality, length of stay, and pressor requirements after liver transplantation
    Celina M Yong
    Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA
    Liver Transpl 16:1242-8. 2010
    ..This study provides preliminary evidence showing that there may be significant prognostic value in coronary angiography as a part of the pretransplant workup...
  13. pmc Injection of bone marrow cell extract into infarcted hearts results in functional improvement comparable to intact cell therapy
    Yerem Yeghiazarians
    Department of Medicine, University of California San Francisco, 94143 0103, USA
    Mol Ther 17:1250-6. 2009
    ..Intact cells are not necessary and death of implanted cells may be a major component of the benefit...
  14. doi Renal and hepatic function improve in advanced heart failure patients during continuous-flow support with the HeartMate II left ventricular assist device
    Stuart D Russell
    Johns Hopkins Hospital, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Circulation 120:2352-7. 2009
    ..The effects of continuous blood flow and reduced pulsatility on major organ function have not been studied in detail...
  15. pmc The aging heart and post-infarction left ventricular remodeling
    Henry Shih
    Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, California 94143, USA
    J Am Coll Cardiol 57:9-17. 2011
    ..We review the cellular and molecular aspects of post-infarction remodeling in the aged heart, and relate them to the clinical problem of post-infarction remodeling in elderly patients...
  16. ncbi Assessment of a novel angiographic image stabilization system for percutaneous coronary intervention
    Andrew J Boyle
    Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Interv Cardiol 20:153-7. 2007
    ..We tested a novel system to stabilize angiographic images at the region of interest in order to assist during PCI...
  17. doi Sterile radial artery granuloma after transradial procedures: a unique and avoidable complication
    Christian Zellner
    Department of Medicine, University of California, San Francisco, CA, USA
    Catheter Cardiovasc Interv 76:673-6. 2010
    ..2010 Wiley-Liss, Inc...
  18. doi Sterile radial artery granuloma after transradial cardiac catheterization
    Christian Zellner
    Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA
    Cardiovasc Revasc Med 12:187-9. 2011
    ..The clinical presentation was suggestive of an infected pseudoaneurysm. Awareness of this entity may help clinicians avoid unnecessary surgical procedures, as these granulomata are transient self-limiting reactions...
  19. pmc A comparison of echocardiography to invasive measurement in the evaluation of pulmonary arterial hypertension in a rat model
    Juha W Koskenvuo
    Division of Cardiology, Department of Medicine, University of California, 505 Parnassus Avenue, Box 0103, San Francisco, CA 94143, USA
    Int J Cardiovasc Imaging 26:509-18. 2010
    ..These non-invasive parameters may be used to replace invasive measurements in detecting successful disease induction and to complement invasive data in the evaluation of PAH severity in a rat model...
  20. ncbi Cardiac Stem Cell Therapy. Need for Optimization of Efficacy and Safety Monitoring
    Peter Oettgen
    Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA
    Circulation 114:353-8. 2006
  21. doi CD45-positive cells are not an essential component in cardiosphere formation
    Jianqin Ye
    Department of Medicine, Division of Cardiology, University of California, San Francisco, San Francisco, CA, USA
    Cell Tissue Res 351:201-5. 2013
    ..0001). Purified CD45(+) cells from CS-forming cells did not form CSs in culture. Thus, BM-derived CD45(+) cells including BM progenitors are neither necessary nor sufficient for CS formation...
  22. doi Safety of cardiac catheterization in patients with end-stage liver disease awaiting liver transplantation
    Madan Sharma
    Division of Cardiology, University of California, San Francisco, San Francisco, California, USA corrected
    Am J Cardiol 103:742-6. 2009
    ..In conclusion, despite severe coagulopathy, left-sided cardiac catheterization may be performed safely in this patient population, with correction of coagulopathy and meticulous attention to procedural technique...
  23. pmc Left ventricular remodeling after myocardial infarction: characterization of a swine model on beta-blocker therapy
    Franca S Angeli
    Division of Cardiology, Department of Medicine, University of California, San Francisco, California, USA
    Comp Med 59:272-9. 2009
    ..These findings suggest a dynamic pattern of remodeling over time in a closed-chest ischemia-reperfusion swine model of acute MI on beta-blocker therapy and may guide future studies...
  24. doi Topical nitroglycerin and lidocaine locally vasodilate the radial artery without affecting systemic blood pressure: a dose-finding phase I study
    David T Majure
    Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, CA 94143, USA
    J Crit Care 27:532.e9-13. 2012
    ..We performed this study to determine if topical nitroglycerin and/or nitroglycerin plus topical lidocaine increases RAD without affecting systemic blood pressure...
  25. doi Clinical outcomes for continuous-flow left ventricular assist device patients stratified by pre-operative INTERMACS classification
    Andrew J Boyle
    Division of Cardiology, Aurora St Luke s Medical Center, 2801 West Kinnickinnic River Parkway, Milwaukee, WI 53215, USA
    J Heart Lung Transplant 30:402-7. 2011
    ..We use the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) to stratify patients with continuous-flow devices and assess outcomes in less severe, but functionally impaired, heart failure patients...
  26. ncbi Coronary air embolism: a case report and review of the literature
    Joud Dib
    Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Catheter Cardiovasc Interv 68:897-900. 2006
    ..A case report of air embolism and methods to prevent this complication from occurring are presented along with various management techniques...
  27. ncbi Is it time to burst the "balloon" for high-risk patients?
    Sukesh C Burjonroppa
    Cardiology Division, Heart and Vascular Center, UCSF, San Francisco, CA 94143, USA
    J Invasive Cardiol 19:347-8. 2007
  28. ncbi Catheter-induced coronary artery dissection: risk factors, prevention and management
    Andrew J Boyle
    Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Invasive Cardiol 18:500-3. 2006
    ..We discuss these risk factors and utilize them to propose methods to prevent dissections. Management options of coronary artery dissection are also discussed...
  29. doi Percutaneous retrograde recanalization of a chronic total coronary artery occlusion in a 7 year old
    Luz Natal-Hernandez
    University of California San Francisco, Box 0103, San Francisco, CA 94143, USA
    Cardiovasc Revasc Med 14:113-7. 2013
    ..Important features of this technique in pediatric patients are discussed...
  30. doi Are ventricular assist devices underutilized?
    Andrew J Boyle
    Division of Cardiology, Aurora St Luke s Medical Center, Milwaukee, Wisconsin 53215, USA
    J Card Surg 25:421-4. 2010
    ....
  31. doi Low thromboembolism and pump thrombosis with the HeartMate II left ventricular assist device: analysis of outpatient anti-coagulation
    Andrew J Boyle
    Division of Cardiology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Heart Lung Transplant 28:881-7. 2009
    ..We evaluated the risk of thromboembolism and hemorrhage related to the degree of anti-coagulation as reflected by the international normalized ratio (INR)...
  32. ncbi Factor Xa inhibitors in acute coronary syndromes and venous thromboembolism
    Celina M Yong
    Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, CA 94143, USA
    Curr Vasc Pharmacol 8:5-11. 2010
    ..In this review, we examine the key recent studies on efficacy and safety of FXa inhibitors in ACS and VTE management...
  33. ncbi Is stem cell therapy ready for patients? Stem Cell Therapy for Cardiac Repair. Ready for the Next Step
    Andrew J Boyle
    Department of Medicine, Division of Cardiology, Institute for Cell Engineering, and Specialized Center for Cell Based Therapy, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Circulation 114:339-52. 2006
  34. ncbi Additive effects of endothelial progenitor cells combined with ACE inhibition and beta-blockade on left ventricular function following acute myocardial infarction
    Andrew J Boyle
    University of Melbourne, Department of Medicine, St Vincent s Hospital, Fitzroy, Victoria, 3065, Australia
    J Renin Angiotensin Aldosterone Syst 6:33-7. 2005
    ..Clinical trials using stem cell therapy in conjunction with standard medical treatment are warranted...
  35. ncbi Intra-coronary high-dose CD34+ stem cells in patients with chronic ischemic heart disease: a 12-month follow-up
    Andrew J Boyle
    Department of Medicine, University of Melbourne, St Vincent s Hospital, Princes St, Fitzroy 3065, Victoria, Australia
    Int J Cardiol 109:21-7. 2006
    ..These results demonstrate the feasibility of G-CSF mobilization, leukapheresis and intracoronary transfer of CD34+ stem cells in patients with CIHD, but longer-term studies are required to ensure that this protocol is safe and effective...
  36. ncbi Inhibition of protein kinase C reduces left ventricular fibrosis and dysfunction following myocardial infarction
    Andrew J Boyle
    Department of Medicine, St Vincent s Hospital, University of Melbourne, Melbourne, Princes Street, Fitzroy 3065, Vic, Australia
    J Mol Cell Cardiol 39:213-21. 2005
    ..PKC-inhibition with ruboxistaurin led to attenuation in both the pathological fibrosis and impaired cardiac function that follow experimental MI, suggesting a possible role for this agent in preventing post-infarction heart failure...