Lynn Boyd

Summary

Affiliation: University of Alabama in Huntsville
Country: USA

Publications

  1. pmc Ubiquitination is involved in secondary growth, not initial formation of polyglutamine protein aggregates in C. elegans
    Gregory A Skibinski
    Department of Biological Sciences, University of Alabama in Huntsville, Huntsville AL 35899, USA
    BMC Cell Biol 13:10. 2012
  2. ncbi request reprint Interactions within the ubiquitin pathway of Caenorhabditis elegans
    Michelle Gudgen
    Department of Biological Sciences, University of Alabama in Huntsville, Huntsville, AL 35899, USA
    Biochem Biophys Res Commun 325:479-86. 2004
  3. pmc Ubiquitin conjugating enzymes participate in polyglutamine protein aggregation
    Rebecca A Howard
    Department of Biological Sciences, University of Alabama in Huntsville, Huntsville, AL 35899, USA
    BMC Cell Biol 8:32. 2007
  4. ncbi request reprint Caenorhabditis elegans UBC-2 functions with the anaphase-promoting complex but also has other activities
    Tyralynn Frazier
    Department of Biological Sciences, University of Alabama in Huntsville, Huntsville, AL 35899, USA
    J Cell Sci 117:5427-35. 2004
  5. ncbi request reprint Analysis of RING finger genes required for embryogenesis in C. elegans
    Rhonda Moore
    Department of Biological Sciences, University of Alabama in Huntsville, Huntsville, Alabama, USA
    Genesis 38:1-12. 2004
  6. pmc Stabilization of cell polarity by the C. elegans RING protein PAR-2
    Yingsong Hao
    Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Dev Cell 10:199-208. 2006

Research Grants

Collaborators

  • Rebecca A Howard
  • Guy A Caldwell
  • Gregory A Skibinski
  • Tyralynn Frazier
  • Yingsong Hao
  • Michelle Gudgen
  • Rhonda Moore
  • Geraldine Seydoux
  • Uma Hota
  • Diane Shakes
  • Anantharaman Chandrasekaran

Detail Information

Publications6

  1. pmc Ubiquitination is involved in secondary growth, not initial formation of polyglutamine protein aggregates in C. elegans
    Gregory A Skibinski
    Department of Biological Sciences, University of Alabama in Huntsville, Huntsville AL 35899, USA
    BMC Cell Biol 13:10. 2012
    ..Thus, UBCs may serve an important role in the cellular response to misfolded proteins and the fate of protein aggregates...
  2. ncbi request reprint Interactions within the ubiquitin pathway of Caenorhabditis elegans
    Michelle Gudgen
    Department of Biological Sciences, University of Alabama in Huntsville, Huntsville, AL 35899, USA
    Biochem Biophys Res Commun 325:479-86. 2004
    ..Using NHL-1 as the E3 in the assays, ubiquitination was observed when both UBC-1 and UBC-13 were present but not with either alone. These data imply that some E2s require dimerization in order to function...
  3. pmc Ubiquitin conjugating enzymes participate in polyglutamine protein aggregation
    Rebecca A Howard
    Department of Biological Sciences, University of Alabama in Huntsville, Huntsville, AL 35899, USA
    BMC Cell Biol 8:32. 2007
    ..In this report, nematode and cell culture models for polyglutamine aggregation are used to investigate the role of the ubiquitin pathway in protein aggregation...
  4. ncbi request reprint Caenorhabditis elegans UBC-2 functions with the anaphase-promoting complex but also has other activities
    Tyralynn Frazier
    Department of Biological Sciences, University of Alabama in Huntsville, Huntsville, AL 35899, USA
    J Cell Sci 117:5427-35. 2004
    ....
  5. ncbi request reprint Analysis of RING finger genes required for embryogenesis in C. elegans
    Rhonda Moore
    Department of Biological Sciences, University of Alabama in Huntsville, Huntsville, Alabama, USA
    Genesis 38:1-12. 2004
    ..5 (an ortholog of rbx1). Embryos from RNAi of the APC11 and rbx1 orthologs were arrested in the cell cycle, confirming the role of these particular RING finger proteins in regulation of the cell cycle. genesis 38:1-12, 2004...
  6. pmc Stabilization of cell polarity by the C. elegans RING protein PAR-2
    Yingsong Hao
    Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Dev Cell 10:199-208. 2006
    ..Our findings suggest that reciprocal inhibitory interactions among PAR proteins stabilize polarity by reinforcing an initial asymmetry in PKC-3...

Research Grants2

  1. Analysis of ubiquitination enzymes in C. elegans
    Lynn Boyd; Fiscal Year: 2005
    ..Fourth, the two interacting pairs, UBC-13 with UBC-1 and UBC-13 with UEV-1, will be studied in vitro to determine the nature of those interactions and how they affect E3 interaction and ubiquitin chain formation. ..