Research Topics
| Dawn BowersSummaryAffiliation: University of Florida Country: USA Publications
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Detail Information
Publications
Apathy and depression: separate factors in Parkinson's diseaseLindsey Kirsch-Darrow
Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida 32611, USA
J Int Neuropsychol Soc 17:1058-66. 2011..Such scoring may be important in providing useful information regarding differential treatment options...- Cognitive declines one year after unilateral deep brain stimulation surgery in Parkinson's disease: a controlled study using reliable changeLaura B Zahodne
Clinical and Health Psychology, University of Florida, Gainesville, FL 32610 0165, USA
Clin Neuropsychol 23:385-405. 2009..Finally, use of Reliable Change highlights the impact of individual variability and indicates that fluency declines likely reflect significant changes in a subset of patients who demonstrate a poorer surgical outcome overall... - Cognition and mood in Parkinson's disease in subthalamic nucleus versus globus pallidus interna deep brain stimulation: the COMPARE trialMichael S Okun
Movement Disorders Center, University of Florida, McKnight Brain Institute, College of Medicine, Department of Neurology, Gainesville, FL 32611, USA
Ann Neurol 65:586-95. 2009..Our aim was to compare in a prospective blinded study the cognitive and mood effects of subthalamic nucleus (STN) vs. globus pallidus interna (GPi) deep brain stimulation (DBS) in Parkinson disease... - Greater improvement in quality of life following unilateral deep brain stimulation surgery in the globus pallidus as compared to the subthalamic nucleusLaura B Zahodne
Department of Clinical and Health Psychology, University of Florida, PO Box 100165, Gainesville, FL 32610 0165, USA
J Neurol 256:1321-9. 2009..Patients receiving GPi DBS reported greater improvements that cannot be explained by differential mood or motor effects; however, verbal fluency changes may have partially contributed to lesser QoL improvements amongst STN patients... - Mood and motor trajectories in Parkinson's disease: multivariate latent growth curve modelingLaura B Zahodne
Department of Clinical and Health Psychology, University of Florida, P O Box 100165, Gainesville, FL 32610 0165, USA
Neuropsychology 26:71-80. 2012..The present study sought to characterize and compare trajectories of apathy, depression, and motor symptoms in PD over 18 months... 
Awareness of expressivity deficits in non-demented Parkinson diseaseAnia E Mikos
Department of Clinical and Health Psychology, University of Florida, Gainesville, FL 32601, USA
Clin Neuropsychol 23:805-17. 2009..These findings highlight the view that diminished emotional expressivity in PD should not be mistaken for decreased subjective emotional experience...
Abnormal affective startle modulation in individuals with psychogenic [corrected] movement disorderPaul J Seignourel
Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida, USA
Mov Disord 22:1265-71. 2007..Abnormal affective startle modulation may be used to help distinguish between malingering and PMD. Future studies using larger samples are needed to better understand the role of emotions in conversion disorder...- Deep brain stimulation and the role of the neuropsychologistMichael S Okun
Department of Neurology, Movement Disorders Center, University of Florida, Gainesville, FL 32610, USA
Clin Neuropsychol 21:162-89. 2007..Additionally, this article will review all aspects of the DBS procedure that can result in mood, cognitive, and behavioral effects and what role(s) the neuropsychologist should play in screening and follow-up... - Do patient's get angrier following STN, GPi, and thalamic deep brain stimulationAdam P Burdick
University of Florida Movement Disorders Center, Department of Neurosurgery, Gainesville, FL, USA
Neuroimage 54:S227-32. 2011.... - Startling facts about emotion in Parkinson's disease: blunted reactivity to aversive stimuliDawn Bowers
Department of Clinical and Health Psychology, McKnight Brain Institute, University of Florida, Gainesville, FL, USA
Brain 129:3356-65. 2006..Future studies are needed to address whether the physiologic blunting observed here might be a useful correlate of apathy... - The case for testing memory with both stories and word lists prior to dbs surgery for Parkinson's DiseaseLaura B Zahodne
Department of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA
Clin Neuropsychol 25:348-58. 2011..One should not rely solely on a word list task because patients exhibiting poor memory for word lists may perform better with stories and therefore deserve an interdisciplinary discussion for DBS surgery... - Depressive symptoms in Parkinson disease correlate with impaired global and specific cognitive performanceHubert H Fernandez
Department of Neurology McKnight Brain Institute, University of Florida, Gainesville, USA
J Geriatr Psychiatry Neurol 22:223-7. 2009..Our study shows that while depressive symptoms correlated with global cognitive performance, naming, verbal memory, and language are the most susceptible cognitive domains affected with depressive symptoms... - Examination of the Lille Apathy Rating Scale in Parkinson diseaseLaura B Zahodne
Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida 32610 0165, USA
Mov Disord 24:677-83. 2009..Although the present study does not compare the LARS to a diagnostic gold standard or promote its utility for diagnosing apathy, it provides further support for the LARS as a promising instrument to examine apathy in PD... - Cognitive declines after unilateral deep brain stimulation surgery in Parkinson's disease: a controlled study using Reliable Change, part IIAnia Mikos
Department of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA
Clin Neuropsychol 24:235-45. 2010..These findings must be interpreted in light of group-level differences between the PD control and DBS patients on demographic and disease-related factors... - Factors related to extended hospital stays following deep brain stimulation for Parkinson's diseaseAnia Mikos
Department of Clinical and Health Psychology, University of Florida, Movement Disorders Center, McKnight Brain Institute, Gainesville FL, USA
Parkinsonism Relat Disord 16:324-8. 2010..This study examined potential factors that might have corresponded to increased post-operative stays following unilateral DBS surgery... - Do stable patients with a premorbid depression history have a worse outcome after deep brain stimulation for Parkinson disease?Michael S Okun
UF Center for Movement Disorders and Neurorestoration, Gainesville, Florida 32607, USA
Neurosurgery 69:357-60; discussion 360-1. 2011..Deep brain stimulation (DBS) has been associated with mood sequelae in a subset of patients operated on in either the subthalamic nucleus or the globus pallidus internus for the treatment of Parkinson disease... - How cautious should we be when assessing apathy with the Unified Parkinson's Disease Rating Scale?Lindsey Kirsch-Darrow
Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, Florida 32610 0165, USA
Mov Disord 24:684-8. 2009..g., 3, 4) continues to increase specificity at the expense of dramatically reducing sensitivity. These findings suggest the use of caution when screening for apathy with item 4 due to its poor sensitivity in relation to the AS... - Right and left dorsolateral pre-frontal rTMS treatment of refractory depression: a randomized, sham-controlled trialWilliam J Triggs
Neurology Service and the Brain Rehabilitation Research Center of Excellence, Department of Veterans Affairs Medical Center, Gainesville, FL 32608 1197, USA
Psychiatry Res 178:467-74. 2010..2007), albeit not statistically significant. These results suggest that somatosensory stimuli that repeatedly engage the left hemisphere may be important to the achievement of therapeutic effect... - Deep brain stimulation in the internal capsule and nucleus accumbens region: responses observed during active and sham programmingMichael S Okun
Department of Neurology, Movement Disorders Center, University of Florida, PO Box 100236, Gainesville, FL 32610, USA
J Neurol Neurosurg Psychiatry 78:310-4. 2007..The stimulation-induced benefits and side effects can be reversibly and blindly applied to a variety of locations in this region... - Pre- and post- GPi DBS neuropsychological profiles in a case of X-linked dystonia-ParkinsonismNobuko Kemmotsu
Department of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA
Clin Neuropsychol 25:141-59. 2011..The possible mechanisms for his stable cognitive performance include the target of his DBS, reduced medication dosage, and improvement in dystonia that may in turn have reduced patient's pain... - Addiction-like manifestations and Parkinson's disease: a large single center 9-year experienceNatlada Limotai
Department of Neurology, Center for Movement Disorders and Neurorestoration, Gainesville, Florida 32611, USA
Int J Neurosci 122:145-53. 2012..Characterize potential risk factors and the relationship of dopamine agonist (DA) withdrawal syndrome (DAWS), dopamine dysregulation syndrome (DDS), and impulse control disorders (ICDs) in Parkinson's disease (PD)... - Faces of emotion in Parkinsons disease: micro-expressivity and bradykinesia during voluntary facial expressionsDawn Bowers
Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, Florida 32601, USA
J Int Neuropsychol Soc 12:765-73. 2006..Taken together, the characterization of Parkinson's disease as a model system for the neuroanatomic dissociation between voluntary and spontaneous expressions may be unjustified... - Are selective serotonin reuptake inhibitors associated with greater apathy in Parkinson's disease?Laura B Zahodne
Department of Neurology, Center for Movement Disorders and Neuro restoration, University of Florida, Gainesville, FL, USA
J Neuropsychiatry Clin Neurosci 24:326-30. 2012..Use of monoamine oxidase B inhibitors was associated with less apathy. Longitudinal studies are needed to evaluate a potential SSRI-induced apathy syndrome in PD... - Emotional state affects gait initiation in individuals with Parkinson's diseaseKelly M Naugle
Comprehensive Center for Pain Research, University of Florida, 1329 SW 16th Street, Rm 5180, P O Box 103628, Gainesville, FL 32610, USA
Cogn Affect Behav Neurosci 12:207-19. 2012.... - Does deep brain stimulation induce apathy in Parkinson's disease?Lindsey Kirsch-Darrow
University of Florida Department of Clinical and Health Psychology, P O Box 100165, Gainesville, FL 32610, USA
Front Biosci 13:5316-22. 2008..This review summarizes and evaluates the current state of the literature on apathy after DBS surgery, discusses methodological limitations in the literature, and makes suggestions for future research... - Depression symptoms in movement disorders: comparing Parkinson's disease, dystonia, and essential tremorKimberly M Miller
Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL 32608, USA
Mov Disord 22:666-72. 2007..Clinicians should be aware that depression is a frequent problem in dystonia and ET, in addition to PD, and inquire about depression symptoms in these patients so that they can be appropriately treated... - Neuropsychological profile of a Filipino gentleman with X-linked dystonia-parkinsonism: a case report of Lubag diseaseLaura L S Howe
Clinical and Health Psychology, McKnight Brain Institute, University of Florida, Gainesville, FL, USA
Clin Neuropsychol 23:100-17. 2009..He was evaluated for suitability for deep brain stimulation surgery. Neuropsychological findings demonstrated diffuse impairment involving memory, visuospatial, language, and executive functioning... - Prevalence of Twiddler's syndrome as a cause of deep brain stimulation hardware failureAdam P Burdick
Department of Neurosurgery, University of Florida, Gainesville, Fla, USA
Stereotact Funct Neurosurg 88:353-9. 2010..It possesses a characteristic presentation and with appropriate diagnostic evaluation it is treatable and future occurrences are preventable... - Clock drawing in the Montreal Cognitive Assessment: recommendations for dementia assessmentCatherine C Price
Department of Clinical and Health Psychology, University of Florida, 101 S Newell Drive, Gainesville, FL 32610, USA
Dement Geriatr Cogn Disord 31:179-87. 2011.... - Differences in startle reactivity during the perception of angry and fearful facesUtaka S Springer
Department of Clinical and Health Psychology, University of Florida Health Science Center, Gainesville, FL 32610, USA
Emotion 7:516-25. 2007.... - Selection of deep brain stimulation candidates in private neurology practices: referral may be simpler than a computerized triage systemGenko Oyama
Department of Neurology, University of Florida, Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, Gainesville, FL 32610, USA
Neuromodulation 15:246-50; discussion 250. 2012..Academic Centers in Selection of DBS Candidates [COMPRESS], NeuroTrax Corp., Bellaire, TX, USA) with traditional triage by a movement disorders specialized neurologist as the gold standard... - Laterality, region, and type of motor dysfunction correlate with cognitive impairment in Parkinson's diseaseLindsy N Williams
Department of Neurology, University of Florida College of Medicine, Gainesville, Florida 32610, USA
Mov Disord 22:141-5. 2007..22, t(105) = -1.95, P = 0.054. We therefore found that right-sided symptoms (for laterality), axial symptoms (for region), and bradykinesia (for type of symptoms) were the best predictors of cognitive function... - Measurement of patient-centered outcomes in Parkinson's disease: what do patients really want from their treatment?Anne N Nisenzon
Department of Clinical and Health Psychology, University of Florida, Health Science Center, P O Box 100165, Gainesville, FL 32610 0165, USA
Parkinsonism Relat Disord 17:89-94. 2011..We therefore argue that taking the patients' perspectives of their condition may allow for a more in-depth assessment of patient goals and subsequent tailoring of care... - Asymmetry of the hippocampus and amygdala in MRI volumetric measurements of normal adultsOtto Pedraza
Department of Clinical and Health Psychology, University of Florida, Box 100165, Gainesville, Florida 32610, USA
J Int Neuropsychol Soc 10:664-78. 2004..These results expand on previous volumetric normative studies and may be relevant to investigators studying the clinical correlates of hippocampal and amygdala volumes... - Cerebral blood flow changes in depressed patients after treatment with repetitive transcranial magnetic stimulation: evidence of individual variabilityStephen E Nadeau
Geriatric Research, Education and Clinical Center, Malcolm Randall Department of Veteran Affairs Medical Center, Gainseville, Florida 32608 1197, USA
Neuropsychiatry Neuropsychol Behav Neurol 15:159-75. 2002..To elucidate the neural mechanisms of depression... - Components of depression in Parkinson diseaseLaura B Zahodne
Department of Clinical and Health Psychology, University of Florida, Gainesville, FL 32610, USA
J Geriatr Psychiatry Neurol 25:131-7. 2012..Future studies should examine the specific neural correlates and treatment response patterns unique to these 3 components... - Self-awareness of deficits in Parkinson diseaseElizabeth Leritz
Department of Clinical and Health Psychology, University of Florida Brain Institute, Gainesville, FL, USA
Clin Neuropsychol 18:352-61. 2004..This suggests the potential interaction of laterality and handedness. The importance of future investigations in PD patients with more severe cognitive impairment is stressed... - Long-term habituation of the smile response with deep brain stimulationUtaka S Springer
Clinical and Health Psychology, McKnight Brain Institute, University of Florida, Gainsville, Florida 32610 0165, USA
Neurocase 12:191-6. 2006..The smiles could not be elicited even with long washout periods. These findings imply potential long-term habituation and changes in the neural chemistry (possibly neuroplasticity) induced by chronic DBS... - Lateralized asymmetry of facial motor evoked potentialsWilliam J Triggs
Department of Neurology and Neuropsychology, McKnight Brain Institute, University of Florida, Gainesville, Florida, USA
Neurology 65:541-4. 2005..Transcranial magnetic stimulation (TMS) was used to test for lateralized asymmetry in the cortical control of muscles of facial expression in the lower face... - What's in a "smile?" Intra-operative observations of contralateral smiles induced by deep brain stimulationMichael S Okun
Movement Disorders Center, University of Florida, Department of Neurology, McKnight Brain Institute, Gaineville, FL 32610, USA
Neurocase 10:271-9. 2004..To describe smiling and euphoria induced by deep brain stimulation (DBS)... - Mayo's older African American normative studies: confirmatory factor analysis of a core batteryOtto Pedraza
Department of Clinical and Health Psychology and McKnight Brain Institute, University of Florida, Gainesville, Florida, USA
J Int Neuropsychol Soc 11:184-91. 2005.... - Mental object rotation in Parkinson's diseaseGregory P Crucian
Department of Neurology, University of Florida, Gainesville, Florida 32610, USA
J Int Neuropsychol Soc 9:1078-87. 2003..Although men and women with PD appear to engage different cognitive processes in this task, the reason for the sex difference remains to be elucidated... - Affect in patients with epilepsy undergoing video/EEG monitoring: retrospective versus momentary assessment and temporal relationship to seizuresKristen S Willard
Department of Psychology, Florida State University, Tallahassee, FL 32306, USA
Epilepsy Behav 8:625-34. 2006..The latter two periods were characterized by significantly less activated positive affect than were the interictal periods...
Research Grants
- Digitizing the Face:Priming,TMS&Hemispheric AsymmetriesDawn Bowers; Fiscal Year: 2004..abstract_text> ..
- Masked Faces in Parkinson Disease: Mechanism & TreatmentDawn Bowers; Fiscal Year: 2007..abstract_text> ..