Daniel C Bowers

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi request reprint Phase I study of oral cyclophosphamide and oral topotecan for children with recurrent or refractory solid tumors
    Daniel C Bowers
    Department of Pediatrics, UT Southwestern Medical Center at Dallas, Dallas, Texas 75390 9063, USA
    Pediatr Blood Cancer 42:93-8. 2004
  2. ncbi request reprint Late-occurring stroke among long-term survivors of childhood leukemia and brain tumors: a report from the Childhood Cancer Survivor Study
    Daniel C Bowers
    Department of Pediatrics, The University of Texas Southwestern Medical School, Dallas, TX 75390 9063, USA
    J Clin Oncol 24:5277-82. 2006
  3. doi request reprint Subsequent neoplasms of the CNS among survivors of childhood cancer: a systematic review
    Daniel C Bowers
    Division of Pediatric Hematology Oncology, University of Texas Southwestern Medical School, Dallas, TX 75390 9063, USA
    Lancet Oncol 14:e321-8. 2013
  4. doi request reprint Back pain among long-term survivors of childhood leukemia
    Daniel C Bowers
    Department of Pediatrics, UT Southwestern Medical Center at Dallas, Dallas, TX, USA
    J Pediatr Hematol Oncol 34:624-9. 2012
  5. doi request reprint mTORC1 activation in childhood ependymoma and response to sirolimus
    Daniel C Bowers
    Department of Pediatrics, University of Texas Southwestern Medical School at Dallas, Dallas, TX 75390, USA
    J Neurooncol 103:797-801. 2011
  6. doi request reprint Survey of long-term follow-up programs in the United States for survivors of childhood brain tumors
    Daniel C Bowers
    Department of Pediatrics MC 9063, UT Southwestern Medical Center at Dallas, Dallas, Texas 75390 9063, USA
    Pediatr Blood Cancer 53:1295-301. 2009
  7. ncbi request reprint Impact of site of tumor recurrence upon survival for children with recurrent or progressive medulloblastoma
    Daniel C Bowers
    Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Texas 75390 9063, USA
    J Neurosurg 107:5-10. 2007
  8. ncbi request reprint Stroke as a late treatment effect of Hodgkin's Disease: a report from the Childhood Cancer Survivor Study
    Daniel C Bowers
    Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9063, USA
    J Clin Oncol 23:6508-15. 2005
  9. ncbi request reprint Prognostic factors in children and adolescents with low-grade oligodendrogliomas
    Daniel C Bowers
    Department of Pediatrics, UT Southwestern Medical School at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390 9063, USA
    Pediatr Neurosurg 37:57-63. 2002
  10. ncbi request reprint Study of the MIB-1 labeling index as a predictor of tumor progression in pilocytic astrocytomas in children and adolescents
    Daniel C Bowers
    Department of Pediatrics, University of Texas Southwestern Medical School at Dallas, Dallas, TX 75390 9063, USA daniel bowers utsouthwestern edu
    J Clin Oncol 21:2968-73. 2003

Detail Information

Publications28

  1. ncbi request reprint Phase I study of oral cyclophosphamide and oral topotecan for children with recurrent or refractory solid tumors
    Daniel C Bowers
    Department of Pediatrics, UT Southwestern Medical Center at Dallas, Dallas, Texas 75390 9063, USA
    Pediatr Blood Cancer 42:93-8. 2004
    ..To determine the maximum-tolerated duration and dose-limiting toxicity of a daily schedule of orally administered cyclophosphamide and topotecan in pediatric patients with recurrent or refractory malignant solid tumors...
  2. ncbi request reprint Late-occurring stroke among long-term survivors of childhood leukemia and brain tumors: a report from the Childhood Cancer Survivor Study
    Daniel C Bowers
    Department of Pediatrics, The University of Texas Southwestern Medical School, Dallas, TX 75390 9063, USA
    J Clin Oncol 24:5277-82. 2006
    ..This report examines the incidence of and risk factors for strokes that occur in > or = 5-year survivors of childhood leukemia and brain tumors...
  3. doi request reprint Subsequent neoplasms of the CNS among survivors of childhood cancer: a systematic review
    Daniel C Bowers
    Division of Pediatric Hematology Oncology, University of Texas Southwestern Medical School, Dallas, TX 75390 9063, USA
    Lancet Oncol 14:e321-8. 2013
    ..The current literature is insufficient to comment about the potential harms and benefits of routine screening for subsequent CNS neoplasms. ..
  4. doi request reprint Back pain among long-term survivors of childhood leukemia
    Daniel C Bowers
    Department of Pediatrics, UT Southwestern Medical Center at Dallas, Dallas, TX, USA
    J Pediatr Hematol Oncol 34:624-9. 2012
    ..The objectives of this study are to determine the prevalence and relative risk (RR) of back pain and identify possible mechanisms of back pain among childhood acute lymphoblastic leukemia (ALL) survivors...
  5. doi request reprint mTORC1 activation in childhood ependymoma and response to sirolimus
    Daniel C Bowers
    Department of Pediatrics, University of Texas Southwestern Medical School at Dallas, Dallas, TX 75390, USA
    J Neurooncol 103:797-801. 2011
    ..Immunohistochemistry for phosphorylated S6, which has been reported to be associated with tumor sensitivity to mTORC1 inhibitors, was positive in this patient's tumor...
  6. doi request reprint Survey of long-term follow-up programs in the United States for survivors of childhood brain tumors
    Daniel C Bowers
    Department of Pediatrics MC 9063, UT Southwestern Medical Center at Dallas, Dallas, Texas 75390 9063, USA
    Pediatr Blood Cancer 53:1295-301. 2009
    ..Despite recognition that childhood brain tumor survivors often suffer multiple late effects following therapy, little is known regarding the long-term follow-up (LTFU) programs for these patients...
  7. ncbi request reprint Impact of site of tumor recurrence upon survival for children with recurrent or progressive medulloblastoma
    Daniel C Bowers
    Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Texas 75390 9063, USA
    J Neurosurg 107:5-10. 2007
    ..The object of this study was to identify prognostic factors for survival among children with recurrent medulloblastoma...
  8. ncbi request reprint Stroke as a late treatment effect of Hodgkin's Disease: a report from the Childhood Cancer Survivor Study
    Daniel C Bowers
    Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9063, USA
    J Clin Oncol 23:6508-15. 2005
    ..The objectives of this report are to examine the incidence of and risk factors for stroke among childhood Hodgkin's disease (HD) survivors...
  9. ncbi request reprint Prognostic factors in children and adolescents with low-grade oligodendrogliomas
    Daniel C Bowers
    Department of Pediatrics, UT Southwestern Medical School at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390 9063, USA
    Pediatr Neurosurg 37:57-63. 2002
    ..Other risk factors, including presenting symptoms, age at diagnosis, MIB-1 LI and the extent of tumor resection, were not associated with an increased frequency of tumor progression...
  10. ncbi request reprint Study of the MIB-1 labeling index as a predictor of tumor progression in pilocytic astrocytomas in children and adolescents
    Daniel C Bowers
    Department of Pediatrics, University of Texas Southwestern Medical School at Dallas, Dallas, TX 75390 9063, USA daniel bowers utsouthwestern edu
    J Clin Oncol 21:2968-73. 2003
    ..The pilocytic astrocytoma (PA) is the most common childhood brain tumor. This report examines the MIB-1 labeling index (LI) as a predictor of progression-free survival (PFS) among childhood PAs...
  11. doi request reprint Low-grade bone lesions in survivors of childhood medulloblastoma/primitive neuroectodermal tumor
    Korgun Koral
    Department of Radiology, University of Texas Southwestern Medical Center at Dallas and Children s Medical Center, 1935 Medical District Drive, Dallas, TX 75235, USA
    Acad Radiol 19:35-9. 2012
    ..The purpose of this study was to assess the frequency of the low-grade bone lesion development in the radiotherapy field in pediatric MB/PNET survivors and describe the imaging characteristics of these lesions...
  12. ncbi request reprint Nonperioperative strokes in children with central nervous system tumors
    Daniel C Bowers
    Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
    Cancer 94:1094-101. 2002
    ..Nonperioperative strokes are rare yet potentially devastating events for children with central nervous system (CNS) tumors. The incidence of and risk factors for nonperioperative strokes in children with CNS tumors is unknown...
  13. pmc Proliferative and metabolic markers in incompletely excised pediatric pilocytic astrocytomas--an assessment of 3 new variables in predicting clinical outcome
    Linda R Margraf
    Department of Pathology, The University of Texas Southwestern Medical School, 5323 Harry Hines Blvd, Dallas, TX 75390 9073, USA
    Neuro Oncol 13:767-74. 2011
    ..001), MCM2 reactivity was not independently associated with outcome. We conclude that MIB-1 labeling remains the best predictor of PFS in pediatric PAs...
  14. doi request reprint Common pediatric cerebellar tumors: correlation between cell densities and apparent diffusion coefficient metrics
    Korgun Koral
    Department of Radiology, University of Texas Southwestern Medical Center and Children s Medical Center, 1935 Medical District Dr, Dallas, TX 75235, USA
    Radiology 268:532-7. 2013
    ..To test whether there is correlation between cell densities and apparent diffusion coefficient (ADC) metrics of common pediatric cerebellar tumors...
  15. doi request reprint Predictive value of interleukin-5 and monocyte chemotactic protein-1 for bacteremia in children with febrile neutropenia
    Victor M Aquino
    Department of Pediatrics, Divisions of Pediatric Hematology and Oncology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75290 9063, USA
    J Pediatr Hematol Oncol 34:e241-5. 2012
    ..Prospective studies should be undertaken to determine whether these parameters retain predictive value in a larger series of patients and can select children for outpatient management or early discharge...
  16. doi request reprint Imaging characteristics of atypical teratoid-rhabdoid tumor in children compared with medulloblastoma
    Korgun Koral
    Department of Radiology, University of Texas Southwestern Medical Center at Dallas, 1935 Motor St, Dallas, TX 75235, USA
    AJR Am J Roentgenol 190:809-14. 2008
    ..The purpose of our study was to compare the imaging characteristics of atypical teratoid-rhabdoid tumor with medulloblastoma and seek distinguishing features that can aid in preoperative diagnosis...
  17. ncbi request reprint Neuropsychological performance and quality of life of 10 year survivors of childhood medulloblastoma
    Ann M Maddrey
    Division of Consult Liaison and Behavioral Medicine, Department of Psychiatry, U T Southwestern Medical Center, The Annette Strauss Center for Neuro Oncology, 5323 Harry Hines Blvd, Dallas, TX 75390 8898, USA
    J Neurooncol 72:245-53. 2005
    ..Cognitive performance, psychosocial functioning and quality of life were assessed in medulloblastoma survivors in the second decade after diagnosis...
  18. doi request reprint Optic nerve tumor in tuberous sclerosis complex is not responsive to sirolimus
    Steven P Sparagana
    Division of Neurology, Texas Scottish Rite Hospital for Children, 2222 Welborn Street, Dallas, TX 75219, USA
    Pediatr Neurol 42:443-6. 2010
    ..The quality of this child's vision has remained normal in both eyes, and she is otherwise asymptomatic with regard to the optic nerve tumor...
  19. doi request reprint Childhood medulloblastoma: current status of biology and treatment
    Laura J Klesse
    Division of Pediatric Hematology Oncology, Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9063, USA
    CNS Drugs 24:285-301. 2010
    ..Ultimately, our understanding of the basic biology of medulloblastoma may lead to further advances in therapy by providing targets that are more specific and potentially less toxic...
  20. ncbi request reprint Pediatric oligodendrogliomas: a study of molecular alterations on 1p and 19q using fluorescence in situ hybridization
    Ravi Raghavan
    Neuropathology Laboratory, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9073, USA
    J Neuropathol Exp Neurol 62:530-7. 2003
    ..Genomic screening on a larger series is clearly indicated to delineate the unique molecular characteristics of these rare pediatric tumors...
  21. ncbi request reprint Primary renal lymphoma presenting with hypertension
    Amy M Becker
    Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9063, USA
    Pediatr Blood Cancer 48:711-3. 2007
    ..PRL is more diagnosed in adults than children. We describe an asymptomatic child who presented with hypertension and was subsequently diagnosed with primary renal lymphoma. This case represents an atypical presentation for PRL...
  22. doi request reprint Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial
    Kent A Robertson
    Department of Pediatrics, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Lancet Oncol 13:1218-24. 2012
    ..We undertook an open-label phase 2 trial to test whether treatment with imatinib mesylate can decrease the volume burden of clinically significant plexiform neurofibromas in patients with NF1...
  23. ncbi request reprint Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children
    Alberto Broniscer
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
    J Neurooncol 76:313-9. 2006
    ..Although the heterogeneity of prognostic factors in our patients made assessment of treatment outcome more difficult, the addition of 6 cycles of temozolomide after radiotherapy did not seem to alter the poor outcome of these patients...
  24. ncbi request reprint Altered irinotecan pharmacokinetics in pediatric high-grade glioma patients receiving enzyme-inducing anticonvulsant therapy
    Kristine R Crews
    Departments of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Clin Cancer Res 8:2202-9. 2002
    ..The purpose of this study was to determine the effect of enzyme-inducing anticonvulsants (EIAs) on the disposition of irinotecan and metabolites in pediatric patients with high-grade glioma...
  25. ncbi request reprint Effect of intrapatient dosage escalation of irinotecan on its pharmacokinetics in pediatric patients who have high-grade gliomas and receive enzyme-inducing anticonvulsant therapy
    Amar Gajjar
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 97:2374-80. 2003
    ..The type and grade of toxicity did not differ between the two patient groups. Increasing the dosage of irinotecan increased the SN-38 AUC in some patients who received concomitant EIA therapy...
  26. ncbi request reprint Rhabdoid tumors in a shared parental environment
    Ryan M Swinney
    Pediatr Blood Cancer 47:343-4. 2006
  27. ncbi request reprint Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children: results of a multiinstitutional study (SJHG-98)
    Alberto Broniscer
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 103:133-9. 2005
    ..The role of chemotherapy in the treatment of children with newly diagnosed diffuse brainstem glioma is uncertain. In the current study, the authors tested the efficacy of temozolomide treatment after radiotherapy (RT) in this setting...
  28. ncbi request reprint Safety and efficacy of repeated monthly carboplatin desensitization
    Matt Morgan
    J Allergy Clin Immunol 114:974-5. 2004