Deborah Bowen

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Genetics as a tool to improve cancer outcomes: ethics and policy
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Box 357120, 1959 North East Pacific, Room A204, Seattle, Washington 98195 7120, USA
    Nat Rev Cancer 6:476-82. 2006
  2. ncbi request reprint Hereditary hemochromatosis: gene discovery and its implications for population-based screening
    W Burke
    Department of Medicine, University of Washington, Seattle 98105, USA
    JAMA 280:172-8. 1998
  3. ncbi request reprint Genetic testing
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, WA 98195, USA
    N Engl J Med 347:1867-75. 2002
  4. ncbi request reprint Family history as a predictor of asthma risk
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Box 357120, 1959 NE Pacific, Seattle, WA 98195, USA
    Am J Prev Med 24:160-9. 2003
  5. pmc Debating clinical utility
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Seattle, Wash 98195 7120, USA
    Public Health Genomics 13:215-23. 2010
  6. pmc Genetic assessment of breast cancer risk in primary care practice
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Seattle, Washington 98195 7120, USA
    Am J Med Genet A 149:349-56. 2009
  7. pmc Translational genomics: seeking a shared vision of benefit
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, WA 98195, USA
    Am J Bioeth 8:54-6; discussion W1-3. 2008
  8. ncbi request reprint Defining purpose: a key step in genetic test evaluation
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, Washington 98195 7120, USA
    Genet Med 9:675-81. 2007
  9. ncbi request reprint Ethical issues arising from the participation of children in genetic research
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle 98195 7120, USA
    J Pediatr 149:S34-8. 2006
  10. ncbi request reprint Ethical obligations and counseling challenges in cancer genetics
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Box 356120, 1959 NE Pacific, Room A204, Seattle, WA 98195 7120, USA
    J Natl Compr Canc Netw 4:185-91. 2006

Detail Information

Publications74

  1. ncbi request reprint Genetics as a tool to improve cancer outcomes: ethics and policy
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Box 357120, 1959 North East Pacific, Room A204, Seattle, Washington 98195 7120, USA
    Nat Rev Cancer 6:476-82. 2006
    ..When the benefits of testing are well established, efforts must also be made to ensure access to genetic services for all who can benefit...
  2. ncbi request reprint Hereditary hemochromatosis: gene discovery and its implications for population-based screening
    W Burke
    Department of Medicine, University of Washington, Seattle 98105, USA
    JAMA 280:172-8. 1998
    ..To evaluate the role of genetic testing in screening for hereditary hemochromatosis to help guide clinicians, policymakers, and researchers...
  3. ncbi request reprint Genetic testing
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, WA 98195, USA
    N Engl J Med 347:1867-75. 2002
  4. ncbi request reprint Family history as a predictor of asthma risk
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Box 357120, 1959 NE Pacific, Seattle, WA 98195, USA
    Am J Prev Med 24:160-9. 2003
    ..Positive family history may have utility in targeting some individual prevention efforts, but the low positive predictive value limits its value as a means to direct environmental remediation efforts...
  5. pmc Debating clinical utility
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Seattle, Wash 98195 7120, USA
    Public Health Genomics 13:215-23. 2010
    ..Addressing each of these issues requires attention to stakeholder values and methods for effective deliberation that incorporate consumer as well as health professional perspectives...
  6. pmc Genetic assessment of breast cancer risk in primary care practice
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Seattle, Washington 98195 7120, USA
    Am J Med Genet A 149:349-56. 2009
    ..Educational efforts may be most successful when they emphasize the value of genetic counseling for individuals at risk for inherited cancer and the connection between genetic risk and specific prevention measures...
  7. pmc Translational genomics: seeking a shared vision of benefit
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, WA 98195, USA
    Am J Bioeth 8:54-6; discussion W1-3. 2008
  8. ncbi request reprint Defining purpose: a key step in genetic test evaluation
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, Washington 98195 7120, USA
    Genet Med 9:675-81. 2007
  9. ncbi request reprint Ethical issues arising from the participation of children in genetic research
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle 98195 7120, USA
    J Pediatr 149:S34-8. 2006
    ..Because genetic information is often accorded special power in our society, careful attention should be paid to how genetic information is collected and used in research involving pediatric participants...
  10. ncbi request reprint Ethical obligations and counseling challenges in cancer genetics
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Box 356120, 1959 NE Pacific, Room A204, Seattle, WA 98195 7120, USA
    J Natl Compr Canc Netw 4:185-91. 2006
    ..Clinicians must also provide emotional support and accurate information about cancer risks and cancer risk reduction measures, including uncertainties. Teamwork among different specialties is important in addressing these challenges...
  11. ncbi request reprint Genetic testing in primary care
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, Washington 98195 7120, USA
    Annu Rev Genomics Hum Genet 5:1-14. 2004
    ..A partnership between medical genetics and primary care will help to ensure the development of effective policies, educational tools, and practice guidelines for the coming era of genomic health care...
  12. ncbi request reprint Ensuring the appropriate use of genetic tests
    Wylie Burke
    Department of Medical History and Ethics, Box 357120, University of Washington, 1959 NE Pacific, Room A204, Seattle, Washington 98195, USA
    Nat Rev Genet 5:955-9. 2004
    ..Other strategies, including resource allocation and matters related to clinical governance - such as practice-guideline development and health-provider education - are also important...
  13. ncbi request reprint Hereditary haemochromatosis: a realistic approach to prevention of iron overload disease in the population
    Wylie Burke
    Department of Medical History and Ethics, Box 357120, University of Washington, 1959 NE Pacific, Room A204, Seattle, WA 98195, USA
    Best Pract Res Clin Haematol 15:315-28. 2002
    ....
  14. pmc Genetic screening
    Wylie Burke
    Department of Bioethics and Humanities, A204 Health Sciences Building, Box 357120, University of Washington, Seattle, WA 98195, USA
    Epidemiol Rev 33:148-64. 2011
    ....
  15. ncbi request reprint Hemochromatosis: genetics helps to define a multifactorial disease
    W Burke
    University of Washington, Seattle 98105, USA
    Clin Genet 54:1-9. 1998
    ..HH is an important paradigm for medical genetics because it offers an opportunity to explore the complexity of gene gene and gene environment interactions...
  16. ncbi request reprint Screening for hereditary hemochromatosis: are DNA-based tests the answer?
    W Burke
    Department of Medicine Box 354765, University of Washington, 4245 Roosevelt Way NE, Seattle, WA 98105, USA
    Mol Med Today 5:428-30. 1999
    ..DNA-based tests do not provide a simple resolution to these questions...
  17. ncbi request reprint Genetic counseling for women with an intermediate family history of breast cancer
    W Burke
    Department of Medicine, Fred Hutchinson Cancer Research Center, University of Washington, Seattle 98195, USA
    Am J Med Genet 90:361-8. 2000
    ....
  18. ncbi request reprint Iron deficiency and iron overload: effects of diet and genes
    W Burke
    Department of Medical History and Ethics, University of Washington, Seattle 98195, USA
    Proc Nutr Soc 60:73-80. 2001
    ..This work is likely to lead to new insights into Fe disorders and potentially to new therapeutic approaches. It will not be complete, however, until coordinated study of both genetic and nutritional factors is undertaken...
  19. ncbi request reprint Misleading presentation of breast cancer in popular magazines
    W Burke
    Department of Medical History and Ethics, University of Washington, Seattle, Wash, USA
    Eff Clin Pract 4:58-64. 2001
    ..Women commonly misunderstand their risk for breast cancer, overestimating both their risk for developing the disease at a young age and their lifetime risk...
  20. ncbi request reprint Contribution of different HFE genotypes to iron overload disease: a pooled analysis
    W Burke
    Department of Medical History and Ethics, University of Washington, Seattle, Washington 98195, USA
    Genet Med 2:271-7. 2000
    ..To determine the contribution of the C282Y and H63D mutations in the HFE gene to clinical expression of hereditary hemochromatosis...
  21. ncbi request reprint Categorizing genetic tests to identify their ethical, legal, and social implications
    W Burke
    Department of Medical History and Ethics, University of Washington, Seattle 98195, USA
    Am J Med Genet 106:233-40. 2001
    ..This approach to test categorization allows a rapid determination of the predominant ELSI concerns for different kinds of genetic tests and identifies the data most urgently needed for test evaluation...
  22. ncbi request reprint Application of population screening principles to genetic screening for adult-onset conditions
    W Burke
    Department of Medical History and Ethics, University of Washington, 1959 NE Pacific, Room A204, Seattle, WA 98195
    Genet Test 5:201-11. 2001
    ....
  23. pmc Systems medicine and the public's health
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Box 357120, 1959 NE Pacific, Room A204, Seattle, WA 98195 7120, USA
    Genome Med 3:47. 2011
    ..See correspondence article: http://genomemedicine.com/content/3/7/43...
  24. ncbi request reprint Genetics education for primary-care providers
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, Washington 98195, USA
    Nat Rev Genet 3:561-6. 2002
    ..Although most have little knowledge of genetics, their expertise in the prudent use of technology is relevant to the task. Successful educational programmes will need to forge partnerships between primary care and genetics...
  25. ncbi request reprint Contributions of public health to genetics education for health care professionals
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, WA 98195 7120, USA
    Health Educ Behav 32:668-75. 2005
    ....
  26. ncbi request reprint Genomics as a probe for disease biology
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle 98195, USA
    N Engl J Med 349:969-74. 2003
  27. ncbi request reprint Effect of exercise on serum androgens in postmenopausal women: a 12-month randomized clinical trial
    Anne McTiernan
    Cancer Prevention Research Program, Fred Hutchinson Cancer Research Center, and Department of Epidemiology, School of Public Health, University of Washington, Seattle, USA
    Cancer Epidemiol Biomarkers Prev 13:1099-105. 2004
    ..The association between exercise and breast cancer risk may be partly explained by the effects of exercise on these hormones...
  28. ncbi request reprint Effects of exercise on metabolic risk variables in overweight postmenopausal women: a randomized clinical trial
    Laura Lewis Frank
    Fred Hutchinson Cancer Research Center, Cancer Prevention, Seattle, WA 98109 1024, USA
    Obes Res 13:615-25. 2005
    ..This study examined the effects of exercise on metabolic risk variables insulin, leptin, glucose, and triglycerides in overweight/obese postmenopausal women...
  29. ncbi request reprint Effects of a moderate intensity exercise intervention on estrogen metabolism in postmenopausal women
    Charlotte Atkinson
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, P O Box 19024, Seattle, WA 98109, USA
    Cancer Epidemiol Biomarkers Prev 13:868-74. 2004
    ..Thus, this 12-month moderate intensity exercise intervention did not significantly alter urinary excretion of 2-OH E(1), 16alpha-OH E(1), or their ratio in this population of women...
  30. ncbi request reprint Effect of a yearlong, moderate-intensity exercise intervention on the occurrence and severity of menopause symptoms in postmenopausal women
    Erin J Aiello
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Cancer Prevention Research Program, Seattle, WA 98109, USA
    Menopause 11:382-8. 2004
    ..To evaluate the effect of moderate-intensity exercise on the occurrence and severity of menopause symptoms...
  31. pmc Health outcomes after stopping conjugated equine estrogens among postmenopausal women with prior hysterectomy: a randomized controlled trial
    Andrea Z LaCroix
    Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M3 A410, PO 19024, Seattle, WA 98109
    JAMA 305:1305-14. 2011
    ..1 years of follow-up because of an increased risk of stroke and little likelihood of altering the balance of risk to benefit by the planned trial termination date. Postintervention health outcomes have not been reported...
  32. ncbi request reprint Effect of exercise on serum estrogens in postmenopausal women: a 12-month randomized clinical trial
    Anne McTiernan
    Cancer Prevention Research Program, The Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Cancer Res 64:2923-8. 2004
    ..The association between increased physical activity and reduced risk for postmenopausal breast cancer may be partly explained by effects on serum estrogens...
  33. ncbi request reprint Worry about ovarian cancer risk and use of screening by high-risk women: how you recruit affects what you find
    M Robyn Andersen
    Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Am J Med Genet A 129:130-5. 2004
    ..High-risk women recruited via mass mailing were less likely than those recruited via physicians or affected relatives to report either worry about their risk or use of ovarian cancer screening tests...
  34. doi request reprint Breast cancer risk communication: assessment of primary care physicians by standardized patients
    Julie O Culver
    Department of Bioethics and Humanities, University of Washington, Seattle, Washington 98195, USA
    Genet Med 11:735-41. 2009
    ..To assess primary care providers' communication about breast cancer risk...
  35. pmc Family history assessment to detect increased risk for colorectal cancer: conceptual considerations and a preliminary economic analysis
    Scott D Ramsey
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North M2 B230, P O Box 19024, Seattle, WA 98109, USA
    Cancer Epidemiol Biomarkers Prev 14:2494-500. 2005
    ..Although the rationale for earlier screening of persons with a family history of colorectal cancer is plausible, there is no direct evidence that earlier assessment is either effective or cost-effective...
  36. ncbi request reprint Gene expression profiling and breast cancer care: what are the potential benefits and policy implications?
    Nina Oestreicher
    University of Washington, Seattle, Washington, USA
    Genet Med 7:380-9. 2005
    ..However, the outcomes associated with gene expression profiling are not clear, and guidelines for the appropriate use of genomic technologies have not been established...
  37. pmc Low-fat, increased fruit, vegetable, and grain dietary pattern, fractures, and bone mineral density: the Women's Health Initiative Dietary Modification Trial
    Anne McTiernan
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, WA 98019, USA
    Am J Clin Nutr 89:1864-76. 2009
    ..The effects of dietary changes on osteoporosis, low bone density, and frequent falls are unestablished...
  38. ncbi request reprint Awareness and concern about ovarian cancer among women at risk because of a family history of breast or ovarian cancer
    M Robyn Andersen
    Cancer Prevention Research Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Obstet Gynecol 189:S42-7. 2003
    ..Almost 75% have not heard much about their risk for ovarian cancer. More than 90% failed to use 1 or another of 2 possible tests used for ovarian cancer screening regularly...
  39. ncbi request reprint Breast cancer risk counseling improves women's functioning
    Deborah J Bowen
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, MP 900, Seattle, WA 98109, USA
    Patient Educ Couns 53:79-86. 2004
    ..Cancer worry decreased in both counseling groups by one scale point (P < 0.05). These results indicate that counseling can relieve women's negative reactions to breast cancer risk...
  40. doi request reprint Educational needs in genetic medicine: primary care perspectives
    Susan B Trinidad
    Department of Medical History and Ethics, University of Washington, Seattle, Wash 98195 7120, USA
    Community Genet 11:160-5. 2008
    ..This study was performed to identify primary care physicians' (PCPs) attitudes toward genetic medicine and their perceived needs for education in this area...
  41. ncbi request reprint Personalized medicine in the era of genomics
    Wylie Burke
    Center for Genomics and Healthcare Equality and Department of Medical History and Ethics, University of Washington, Seattle, WA 98195, USA
    JAMA 298:1682-4. 2007
  42. doi request reprint Clinical validity and clinical utility of genetic tests
    Wylie Burke
    University of Washington, Seattle, Washington, USA
    Curr Protoc Hum Genet . 2004
    ..This unit defines clinical validity and clinical utility, provides examples, and considers the implications of these test properties for clinical practice...
  43. ncbi request reprint Potential for genetics to promote public health: genetics research on smoking suggests caution about expectations
    Chris Carlsten
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, Occupational and Environmental Medicine Program, University of Washington, Seattle, USA
    JAMA 296:2480-2. 2006
  44. ncbi request reprint Pharmacogenomic testing to prevent aminoglycoside-induced hearing loss in cystic fibrosis patients: potential impact on clinical, patient, and economic outcomes
    David L Veenstra
    Institute for Public Health Genetics, Department of Pharmacy, University of Washington, Seattle, Washington 98195, USA
    Genet Med 9:695-704. 2007
    ..Although the A1555G variant is very rare, it seems to confer a high risk of severe hearing loss in patients exposed to aminoglycosides...
  45. ncbi request reprint Effects of risk counseling on interest in breast cancer genetic testing for lower risk women
    Deborah J Bowen
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Genet Med 4:359-65. 2002
    ..A randomized trial was conducted to test the effects of two counseling methods (genetic counseling and group counseling) against a control no-intervention condition on interest in genetic testing in lower risk women...
  46. pmc Diabetes and HFE mutations: cause or coincidence?
    Linda E Pinsky
    Department of Medicine, Division of General Internal Medicine, University of Washington Medical Center, 4245 Roosevelt Way, NE Seattle, WA 98105 6920, USA
    West J Med 176:114-5. 2002
  47. pmc Population description and its role in the interpretation of genetic association
    Stephanie M Fullerton
    Department of Bioethics and Humanities, Center for Genomics and Healthcare Equality, University of Washington School of Medicine, Box 357120, Seattle, WA 98195, USA
    Hum Genet 127:563-72. 2010
    ..Instead, criteria which help investigators better distinguish justified and unjustified forms of population generalization may be required...
  48. pmc A formal risk-benefit framework for genomic tests: facilitating the appropriate translation of genomics into clinical practice
    David L Veenstra
    Department of Pharmacy, University of Washington, Seattle, Washington 98195, USA
    Genet Med 12:686-93. 2010
    ..To address these issues, this study presents a risk-benefit framework for assessing the health-related utility of genomic tests...
  49. doi request reprint Low-fat dietary pattern and risk of treated diabetes mellitus in postmenopausal women: the Women's Health Initiative randomized controlled dietary modification trial
    Lesley F Tinker
    Women s Health Initiative, Fred Hutchinson Cancer Research Center, PO Box 19024, Mail Stop M3 A410, Seattle, WA 98109, USA
    Arch Intern Med 168:1500-11. 2008
    ..This study was undertaken to assess the effects of a low-fat dietary pattern on incidence of treated diabetes among generally healthy postmenopausal women...
  50. doi request reprint Physician-patient colorectal cancer screening discussions by physicians' screening rates
    Cathleen M O'Farrell
    Department of Family Medicine, University of Washington, Seattle, WA 98195 4982, USA
    J Am Board Fam Med 25:771-81. 2012
    ..To better understand this finding, we explored the relationship between the content of hypothetical patient-physician CRC screening discussions and CRC screening rates in physicians' practices...
  51. pmc Evaluation of Cancer 101: an educational program for native settings
    Teresa Garrett Hill
    Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    J Cancer Educ 25:329-36. 2010
    ..Cancer 101 provides a critical pathway to increase knowledge and promote action to reduce the burden and improve survival of cancer within tribal communities...
  52. ncbi request reprint Effects of a yearlong moderate-intensity exercise and a stretching intervention on sleep quality in postmenopausal women
    Shelley S Tworoger
    The Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Cancer Prevention Research Program, Seattle, Wash 98109 1024, USA
    Sleep 26:830-6. 2003
    ....
  53. pmc Reconsidering the family history in primary care
    Eugene C Rich
    Department of Medicine, Creighton University, 601 N 30th Street, Suite 8850, Omaha, NE 68131, USA
    J Gen Intern Med 19:273-80. 2004
    ....
  54. ncbi request reprint Practicing moral medicine: patient care to public health
    Denise M Dudzinski
    University of Washington, USA
    Am J Bioeth 6:75-6. 2006
  55. doi request reprint Clinical validity and clinical utility of genetic tests
    Wylie Burke
    University of Washington, Seattle, Washington, USA
    Curr Protoc Hum Genet . 2009
    ..This unit defines clinical validity and clinical utility, provides examples, and considers the implications of these test properties for clinical practice...
  56. pmc Motivating factors for physician ordering of factor V Leiden genetic tests
    Lucia A Hindorff
    Department of Epidemiology, University of Washington, Seattle, USA
    Arch Intern Med 169:68-74. 2009
    ..The factor V Leiden (FVL) genetic test is used by many physicians despite its uncertain clinical utility...
  57. ncbi request reprint Low-fat dietary pattern and risk of colorectal cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial
    Shirley A A Beresford
    Department of Epidemiology, University of Washington, Seattle, WA 98195 7236, USA
    JAMA 295:643-54. 2006
    ..Observational studies and polyp recurrence trials are not conclusive regarding the effects of a low-fat dietary pattern on risk of colorectal cancer, necessitating a primary prevention trial...
  58. pmc A case study of the South Puget Intertribal Planning Agency's comprehensive cancer control planning and community mobilization process
    Carrie Nass
    National Cancer Institute s Cancer Information Service Northwest Region, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, J2 400, P O Box 19024, Seattle, WA 98109, USA
    Prev Chronic Dis 5:A53. 2008
    ..The high rates of cancer among American Indians and Alaska Natives are of growing concern...
  59. ncbi request reprint The path from genome-based research to population health: development of an international public health genomics network
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, WA 98195 7120, USA
    Genet Med 8:451-8. 2006
  60. ncbi request reprint Genetic test evaluation: information needs of clinicians, policy makers, and the public
    Wylie Burke
    University of Washington, Seattle, WA, USA
    Am J Epidemiol 156:311-8. 2002
    ....
  61. ncbi request reprint Effects of individual and family functioning on interest in genetic testing
    Deborah J Bowen
    Fred Hutchinson Cancer Research Center, Seattle, Wash 98109, USA
    Community Genet 7:25-32. 2004
    ..The present study reports on the important issue of how family communication and support regarding breast cancer risk affects interest in genetic testing and mental health...
  62. ncbi request reprint Achieving utility with family history: colorectal cancer risk
    Deborah J Bowen
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, MP900, Seattle, WA 98109, USA
    Am J Prev Med 24:177-82. 2003
    ..Where available, we cite data to support the issues that could arise. Where there are no studies, we invite further research. The potential of family history as a health improvement tool is still under review...
  63. pmc Researcher perspectives on disclosure of incidental findings in genetic research
    Meredith C Meacham
    University of Washington s Institute of Public Health Genetics Master of Public Health program, Seattle, WA 98195 7120, USA
    J Empir Res Hum Res Ethics 5:31-41. 2010
    ....
  64. ncbi request reprint Jewish identity and intentions to obtain breast cancer screening
    Deborah J Bowen
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, MP900, Seattle, Washington 98109, USA
    Cultur Divers Ethnic Minor Psychol 9:79-87. 2003
    ..Religious identity was a significant predictor of intention to adhere to mammography recommendations. Findings show that culture and religion, although correlated, may have different associations with health attitudes...
  65. pmc The asthma consultative process: a collaborative approach to integrating genomics into public health practice
    Tabitha A Harrison
    Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98105, USA
    Prev Chronic Dis 2:A27. 2005
    ..This paper describes the methods used to conduct these professional and community consultations, referred to as the asthma consultative process, and discusses the lessons learned from this activity...
  66. pmc Does genomic risk information motivate people to change their behavior?
    Nora B Henrikson
    Group Health Cooperative, Center for Health Studies, 1730 Minor Ave, Suite 1600, Seattle, WA 98101, USA
    Genome Med 1:37. 2009
    ....
  67. ncbi request reprint Predictors of women's Internet access and Internet health seeking
    Deborah Bowen
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Health Care Women Int 24:940-51. 2003
    ..Internet use motivators are complex; these findings have relevance to the design of Internet-based interventions...
  68. ncbi request reprint Incorporating principles and practical wisdom in research ethics education: a preliminary study
    Nicole Deming
    Department of Medical History and Ethics, University of Washington School of Medicine, Seattle, WA 98195 7120, USA
    Acad Med 82:18-23. 2007
    ..This study characterized researchers' responses to ethical dilemmas with the goal of aligning research ethics education programs with the demands of practice...
  69. pmc Genomic research and wide data sharing: views of prospective participants
    Susan Brown Trinidad
    Department of Bioethics and Humanities, University of Washington, Seattle, WA 98195 7120, USA
    Genet Med 12:486-95. 2010
    ..This study was designed to explore the perceptions, beliefs, and attitudes of research participants and possible future participants regarding genome-wide association studies and repository-based research...
  70. ncbi request reprint Effects of counseling Ashkenazi Jewish women about breast cancer risk
    Deborah J Bowen
    Department of Health Services, University of Washington, Seattle, WA 98109, USA
    Cultur Divers Ethnic Minor Psychol 12:45-56. 2006
    ..Counseling can help women gain a more accurate perception of their risk, expose them to the benefits and limitations of genetic testing, and reduce their worry about cancer...
  71. doi request reprint Cytochrome p450 enzyme polymorphism frequency in indigenous and native american populations: a systematic review
    Cheedy Jaja
    Center for Genomics and Healthcare Equality, University of Washington, Seattle, Wash, USA
    Community Genet 11:141-9. 2008
    ..The purpose of our study was to evaluate the evidence on the prevalence of cytochrome P450 enzyme polymorphisms as potential genetic factors influencing drug efficacy and safety in the indigenous populations of the American hemispheres...
  72. pmc Use of Factor V Leiden genetic testing in practice and impact on management
    Anne Marie Laberge
    Institute for Public Health Genetics, Center for Genomics and Healthcare Equality, University of Washington, Seattle, Washington, USA
    Genet Med 11:750-6. 2009
    ..To assess the use of the genetic test for Factor V Leiden in clinical practice, physician adherence to national and local guidelines, and impacts of test results on patient management...
  73. ncbi request reprint Genetic information: Special or not? Responses from focus groups with members of a health maintenance organization
    Brenda Diergaarde
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Am J Med Genet A 143:564-9. 2007
    ..These data may guide future research and policy concerning the use and protection of medical information, including genetic information...
  74. pmc An economic viewpoint on alternative strategies for identifying persons with hereditary nonpolyposis colorectal cancer
    Scott D Ramsey
    Fred Hutchinson Cancer Research Center, and Department of Medicine, University of Washington, Seattle, Washington, USA
    Genet Med 5:353-63. 2003
    ..There is uncertainty regarding the optimal strategy for identifying mutation carriers among those with hereditary nonpolyposis colorectal cancer (HNPCC)...

Research Grants10

  1. Genomic Health Care and the Medically Underserved
    Wylie Burke; Fiscal Year: 2007
    ..abstract_text> ..
  2. EVALUATING USE OF GENETIC INFORMATION: A MODEL PROCESS
    Wylie Burke; Fiscal Year: 2003
    ..5. To conduct an evaluation of the model process within a large health care system. ..
  3. Motivating Integrity in Research with Human Subjects
    Wylie Burke; Fiscal Year: 2003
    ..abstract_text> ..
  4. Genomic Health Care and the Medically Underserved
    Wylie Burke; Fiscal Year: 2007
    ..abstract_text> ..