Andrew J M Boulton

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. ncbi request reprint Clinical practice. Neuropathic diabetic foot ulcers
    Andrew J M Boulton
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Miami School of Medicine, Miami, FL 33101, USA
    N Engl J Med 351:48-55. 2004
  2. pmc Comprehensive foot examination and risk assessment: a report of the task force of the foot care interest group of the American Diabetes Association, with endorsement by the American Association of Clinical Endocrinologists
    Andrew J M Boulton
    Manchester Diabetes Centre, Manchester, UK
    Diabetes Care 31:1679-85. 2008
  3. doi request reprint The pathway to foot ulceration in diabetes
    Andrew J M Boulton
    European Association for the Study of Diabetes, Dusseldorf, Germany
    Med Clin North Am 97:775-90. 2013
  4. pmc Mechanisms and management of diabetic painful distal symmetrical polyneuropathy
    Solomon Tesfaye
    Diabetes Research Unit, Sheffield Teaching Hospitals, Royal Hallamshire Hospital, Sheffield, UK
    Diabetes Care 36:2456-65. 2013
  5. doi request reprint Diabetic neuropathy: is pain God's greatest gift to mankind?
    Andrew J M Boulton
    Universities of Manchester, Manchester, UK
    Semin Vasc Surg 25:61-5. 2012
  6. doi request reprint Diabetic foot--what can we learn from leprosy? Legacy of Dr Paul W. Brand
    Andrew J M Boulton
    University of Manchester, Manchester, UK
    Diabetes Metab Res Rev 28:3-7. 2012
  7. pmc Hydrodebridement of wounds: effectiveness in reducing wound bacterial contamination and potential for air bacterial contamination
    Frank L Bowling
    Department of Medicine Manchester Royal Infirmary, University of Manchester, Manchester, UK
    J Foot Ankle Res 2:13. 2009
  8. doi request reprint The diabetic foot--an update
    Andrew J M Boulton
    University of Manchester, Manchester, UK
    Foot Ankle Surg 14:120-4. 2008
  9. ncbi request reprint What you can't feel can hurt you
    Andrew J M Boulton
    Manchester Diabetes Centre, 193 Hathersage Rd, Manchester M13 0JE, England
    J Am Podiatr Med Assoc 100:349-52. 2010
  10. doi request reprint What you can't feel can hurt you
    Andrew J M Boulton
    Manchester Royal Infirmary, and the Universities of Manchester, UK
    J Vasc Surg 52:28S-30S. 2010

Detail Information

Publications86

  1. ncbi request reprint Clinical practice. Neuropathic diabetic foot ulcers
    Andrew J M Boulton
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Miami School of Medicine, Miami, FL 33101, USA
    N Engl J Med 351:48-55. 2004
  2. pmc Comprehensive foot examination and risk assessment: a report of the task force of the foot care interest group of the American Diabetes Association, with endorsement by the American Association of Clinical Endocrinologists
    Andrew J M Boulton
    Manchester Diabetes Centre, Manchester, UK
    Diabetes Care 31:1679-85. 2008
  3. doi request reprint The pathway to foot ulceration in diabetes
    Andrew J M Boulton
    European Association for the Study of Diabetes, Dusseldorf, Germany
    Med Clin North Am 97:775-90. 2013
    ....
  4. pmc Mechanisms and management of diabetic painful distal symmetrical polyneuropathy
    Solomon Tesfaye
    Diabetes Research Unit, Sheffield Teaching Hospitals, Royal Hallamshire Hospital, Sheffield, UK
    Diabetes Care 36:2456-65. 2013
    ..S. and several European countries. All patients with DSPN are at increased risk of foot ulceration and require foot care, education, and if possible, regular podiatry assessment. ..
  5. doi request reprint Diabetic neuropathy: is pain God's greatest gift to mankind?
    Andrew J M Boulton
    Universities of Manchester, Manchester, UK
    Semin Vasc Surg 25:61-5. 2012
    ..Similarly, it must be remembered when treating neuropathic foot lesions that patients will willingly weight-bear on plantar ulcers: suitable offloading is therefore the first-line treatment for such lesions...
  6. doi request reprint Diabetic foot--what can we learn from leprosy? Legacy of Dr Paul W. Brand
    Andrew J M Boulton
    University of Manchester, Manchester, UK
    Diabetes Metab Res Rev 28:3-7. 2012
    ..In summary, Brand's understanding of 'the gift of pain' that, when lost, results in the late complications of diabetic neuropathy has guided the prevention, diagnosis and management of diabetic foot problems in the 21st century...
  7. pmc Hydrodebridement of wounds: effectiveness in reducing wound bacterial contamination and potential for air bacterial contamination
    Frank L Bowling
    Department of Medicine Manchester Royal Infirmary, University of Manchester, Manchester, UK
    J Foot Ankle Res 2:13. 2009
    ..The purpose of this study was to assess the level of air contamination with bacteria after surgical hydrodebridement and to determine the effectiveness of hydro surgery on bacterial reduction of a simulated infected wound...
  8. doi request reprint The diabetic foot--an update
    Andrew J M Boulton
    University of Manchester, Manchester, UK
    Foot Ankle Surg 14:120-4. 2008
    ..The next decades will undoubtedly see the application of stem cell therapy in the management of diabetic foot ulceration...
  9. ncbi request reprint What you can't feel can hurt you
    Andrew J M Boulton
    Manchester Diabetes Centre, 193 Hathersage Rd, Manchester M13 0JE, England
    J Am Podiatr Med Assoc 100:349-52. 2010
    ..If we are to succeed in reducing the high incidence of foot ulceration and particularly recurrent ulceration, we must realize that with loss of pain there is also diminished motivation in the healing and prevention of injury...
  10. doi request reprint What you can't feel can hurt you
    Andrew J M Boulton
    Manchester Royal Infirmary, and the Universities of Manchester, UK
    J Vasc Surg 52:28S-30S. 2010
    ..If we are to succeed in reducing the high incidence of foot ulceration and, particularly, recurrent ulceration, we must realize that with loss of pain there is also diminished motivation in the healing and the prevention of injury...
  11. ncbi request reprint Therapeutic footwear in diabetes: the good, the bad, and the ugly?
    Andrew J M Boulton
    Department of Medicine, Manchester Royal Infirmary, Manchester, UK
    Diabetes Care 27:1832-3. 2004
  12. ncbi request reprint Pressure and the diabetic foot: clinical science and offloading techniques
    Andrew J M Boulton
    Department of Medicine, University of Miami, Florida 33101, USA
    Am J Surg 187:17S-24S. 2004
    ....
  13. ncbi request reprint Diabetic somatic neuropathies
    Andrew J M Boulton
    Division of Endocrinology, University of Miami School of Medicine, P O Box 016960 D 110, Miami, Florida, USA
    Diabetes Care 27:1458-86. 2004
  14. doi request reprint The diabetic foot: grand overview, epidemiology and pathogenesis
    Andrew J M Boulton
    Universities of Manchester, Manchester, UK
    Diabetes Metab Res Rev 24:S3-6. 2008
    ..Some recent exciting developments are highlighted. This is followed by a brief discussion on the epidemiology and causal pathways to diabetic foot disease...
  15. ncbi request reprint Diabetic neuropathies: a statement by the American Diabetes Association
    Andrew J M Boulton
    Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, U K
    Diabetes Care 28:956-62. 2005
  16. ncbi request reprint Treatment of symptomatic diabetic neuropathy
    Andrew J M Boulton
    University of Manchester, Manchester, UK University of Miami School of Medicine, Miami, Florida, USA
    Diabetes Metab Res Rev 19:S16-21. 2003
    ..Additionally, other pharmacological and non-pharmacological pain management approaches may be useful. Patient education has a significant role to play in the avoidance of late neurological complications...
  17. ncbi request reprint The global burden of diabetic foot disease
    Andrew J M Boulton
    Department of Medicine, University of Manchester, Manchester, UK
    Lancet 366:1719-24. 2005
    ..An integrated care approach with regular screening and education of patients at risk requires low expenditure and has the potential to reduce the cost of health care...
  18. ncbi request reprint Patient Interpretation of Neuropathy (PIN) questionnaire: an instrument for assessment of cognitive and emotional factors associated with foot self-care
    Loretta Vileikyte
    Department of Medicine, University of Manchester, Oxford Road, Manchester M13 WL9, U K
    Diabetes Care 29:2617-24. 2006
    ..Using the common-sense model of illness behavior, we developed and validated a self-report instrument for assessment of patients' cognitive and emotional representations of diabetic peripheral neuropathy (DPN) influencing foot self-care...
  19. pmc Corneal confocal microscopy: a novel noninvasive test to diagnose and stratify the severity of human diabetic neuropathy
    Mitra Tavakoli
    Division of Cardiovascular Medicine, University of Manchester and Central Manchester Foundation Trust, Manchester, U K
    Diabetes Care 33:1792-7. 2010
    ..The accurate quantification of human diabetic neuropathy is important to define at-risk patients, anticipate deterioration, and assess new therapies...
  20. pmc High levels of foot ulceration and amputation risk in a multiracial cohort of diabetic patients on dialysis therapy
    Agbor Ndip
    Manchester Diabetes Centre, Manchester Academic Health Science Centre, Manchester National Institute of Health Research Biomedical Research Centre, Central Manchester University Hospitals National Health Service Foundation Trust, Manchester, UK
    Diabetes Care 33:878-80. 2010
    ..To evaluate the prevalence of lower-limb complications in a multiracial cohort of patients with diabetes receiving dialysis...
  21. pmc Dialysis treatment is an independent risk factor for foot ulceration in patients with diabetes and stage 4 or 5 chronic kidney disease
    Agbor Ndip
    Manchester Diabetes Centre, Manchester Academic Health Science Centre, Manchester National Institute Health Research Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, U K
    Diabetes Care 33:1811-6. 2010
    ..To determine whether dialysis treatment is an independent risk factor for foot ulceration in patients with diabetes and renal impairment...
  22. ncbi request reprint Corneal confocal microscopy detects early nerve regeneration after pancreas transplantation in patients with type 1 diabetes
    Sanjay Mehra
    Transplant Unit, Manchester Royal Infirmary, Manchester, UK
    Diabetes Care 30:2608-12. 2007
    ..We have used it to assess the neurological benefits of pancreas transplantation in type 1 diabetic patients...
  23. ncbi request reprint Diabetic peripheral neuropathy and depressive symptoms: the association revisited
    Loretta Vileikyte
    Department of Medicine, University of Manchester, UK
    Diabetes Care 28:2378-83. 2005
    ..We examined the association between severity of diabetic peripheral neuropathy and depressive symptoms and investigated the potential mediators of this association...
  24. ncbi request reprint The use of superoxidized aqueous solution versus saline as a replacement solution in the versajet lavage system in chronic diabetic foot ulcers: a pilot study
    Frank L Bowling
    University Department of Medicine and Diabetes, Manchester Royal Infirmary, Manchester, England
    J Am Podiatr Med Assoc 101:124-6. 2011
    ..Hydrodebridement (jet lavage) and superoxidized aqueous solution have been independently used for debriding wounds. We sought to investigate the use of superoxidized aqueous solution with a jet lavage system...
  25. ncbi request reprint Surrogate markers of small fiber damage in human diabetic neuropathy
    Cristian Quattrini
    Division of Cardiovascular Medicine, University of Manchester, Manchester Diabetes Centre and Manchester Royal Infirmary, Manchester, UK
    Diabetes 56:2148-54. 2007
    ..This may make it an ideal technique to accurately diagnose and assess progression of human diabetic neuropathy...
  26. doi request reprint Whither pathogenetic treatments for diabetic polyneuropathy?
    Andrew J M Boulton
    Centre for Endocrinology and Diabetes, University of Manchester, Manchester, UK
    Diabetes Metab Res Rev 29:327-33. 2013
    ..These advances in DSPN disease modification need to be confirmed with further robust evidence from clinical trials together with a better understanding of the mechanisms of action of promising treatments...
  27. ncbi request reprint Can motor nerve conduction velocity predict foot problems in diabetic subjects over a 6-year outcome period?
    Anne L Carrington
    Department of Medicine, Manchester Royal Infirmary, Manchester, U K
    Diabetes Care 25:2010-5. 2002
    ..This study examined motor nerve conduction velocity (MNCV) and other peripheral nerve and vascular tests as predictors for foot ulceration, amputation, and mortality in diabetes over a 6-year follow-up period...
  28. ncbi request reprint Reduction of plantar pressure using a prototype pressure-relieving dressing
    Carine H M van Schie
    Manchester Diabetes Centre, Manchester Royal Infirmary, UK
    Diabetes Care 28:2236-7. 2005
  29. ncbi request reprint Reduced vascular endothelial growth factor expression and intra-epidermal nerve fiber loss in human diabetic neuropathy
    Cristian Quattrini
    Division of Cardiovascular Medicine, University of Manchester and Manchester Diabetes Centre, Manchester Royal Infirmary, Manchester, UK
    Diabetes Care 31:140-5. 2008
    ....
  30. pmc Liquid silicone to mitigate plantar pedal pressure: a literature review
    Frank L Bowling
    Central Manchester Foundation Trust, Manchester Diabetes Centre, University of Manchester, Manchester, United Kingdom
    J Diabetes Sci Technol 4:846-52. 2010
    ..In situations where the patient is sensate, the resultant skin on bone situation is extremely painful, especially when walking...
  31. ncbi request reprint A randomized trial of two irremovable off-loading devices in the management of plantar neuropathic diabetic foot ulcers
    Ira A Katz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Miami, DRI Building, 1450 N W 10th Ave, Room 3054, P O Box 016960 D110, Miami, FL 33101, USA
    Diabetes Care 28:555-9. 2005
    ..The purpose of this study was to compare the effectiveness of a removable cast walker (RCW) rendered irremovable (iTCC) with the total contact cast (TCC) in the treatment of diabetic neuropathic plantar foot ulcers...
  32. ncbi request reprint Larval therapy: a novel treatment in eliminating methicillin-resistant Staphylococcus aureus from diabetic foot ulcers
    Frank L Bowling
    University Department of Medicine and Diabetes, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, U K
    Diabetes Care 30:370-1. 2007
  33. ncbi request reprint Diabetic neuropathy: classification, measurement and treatment
    Andrew J M Boulton
    University of Manchester, Manchester, UK
    Curr Opin Endocrinol Diabetes Obes 14:141-5. 2007
    ..This review considers recent developments in the classification and noninvasive assessment of somatic neuropathy, and describes new approaches to the management of painful neuropathic symptoms...
  34. ncbi request reprint The development and validation of a neuropathy- and foot ulcer-specific quality of life instrument
    Loretta Vileikyte
    Departments of Medicine and Behavioral Science, Manchester Royal Infirmary, Manchester, UK
    Diabetes Care 26:2549-55. 2003
    ....
  35. ncbi request reprint Plantar soft-tissue thickness predicts high peak plantar pressure in the diabetic foot
    Frag Abouaesha
    Department of Medicine, Manchester Royal Infirmary, University of Manchester, Manchester, England
    J Am Podiatr Med Assoc 94:39-42. 2004
    ..The results of the study indicate that high plantar pressure can be predicted from plantar tissue thickness with high sensitivity and specificity...
  36. ncbi request reprint Mortality in diabetic and nondiabetic patients after amputations performed from 1990 to 1995: a 5-year follow-up study
    Nicholas Tentolouris
    University of Manchester, Department of Medicine, Manchester Royal Infirmary, Manchester, UK
    Diabetes Care 27:1598-604. 2004
    ..Survival status was assessed from the first amputation until 31 December 2001...
  37. ncbi request reprint The neuropathic diabetic foot
    Haris M Rathur
    Academic Department of Medicine, University of Manchester, Manchester, UK
    Nat Clin Pract Endocrinol Metab 3:14-25. 2007
    ..The success of other approaches to offloading similarly depends on the patient's adherence to the strategy used for pressure relief...
  38. pmc Explanations for the lower rates of diabetic neuropathy in Indian Asians versus Europeans
    Caroline A Abbott
    Cardiovascular Research Group, School of Biomedicine, University of Manchester, Manchester, UK
    Diabetes Care 33:1325-30. 2010
    ..K., possibly due to less neuropathy. We therefore compared signs, symptoms, and objective quantitative measures of diabetic neuropathy and their risk factors in Indian Asians and Europeans...
  39. ncbi request reprint Offloading diabetic foot wounds using the scotchcast boot: a retrospective study
    E Ann Knowles
    Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK
    Ostomy Wound Manage 48:50-3. 2002
    ....
  40. ncbi request reprint The Diabetic Foot in 2008: an update from the 12th Malvern Diabetic Foot Meeting
    Agbor Ndip
    Diabetes Centre, Central Manchester and Manchester Children s University NHS Trust, Manchester, UK
    Int J Low Extrem Wounds 7:235-8. 2008
    ..This review puts together key messages emanating from the meeting. All effort has been made to highlight clearly where consensus exists as well as outline areas where controversy persists...
  41. doi request reprint Diabetic foot disease in people with advanced nephropathy and those on renal dialysis
    Agbor Ndip
    Diabetes Centre Department of Medicine, Manchester Royal Infirmary, 193 Hathersage Road, Manchester, M13 0JE, UK
    Curr Diab Rep 10:283-90. 2010
    ..Recent studies have demonstrated improved foot outcomes when chiropody programs are instituted within dialysis units...
  42. doi request reprint Critically evaluating the role of diagnostic imaging in osteomyelitis
    David Hankin
    Central Manchester Foundation Trust, Manchester Diabetes Centre, Manchester Diabetes Centre, UK
    Foot Ankle Spec 4:100-5. 2011
    ..Sequential selection of appropriate imaging modalities requires a thorough understanding of the disease processes and the process by which each modality visualizes this dynamic disease process...
  43. pmc Prevalence and characteristics of painful diabetic neuropathy in a large community-based diabetic population in the U.K
    Caroline A Abbott
    Division of Cardiovascular Medicine, Core Technology Facility, University of Manchester, Manchester, UK
    Diabetes Care 34:2220-4. 2011
    ....
  44. ncbi request reprint Corneal sensitivity is reduced and relates to the severity of neuropathy in patients with diabetes
    Mitra Tavakoli
    Division of Cardiovascular Medicine, University of Manchester and Manchester Royal Infirmary, Manchester, M13 9NT, UK
    Diabetes Care 30:1895-7. 2007
  45. ncbi request reprint The diabetic foot
    Haris M Rathur
    Department of Medicine, Manchester Royal Infirmary, Manchester M13 9WL, UK
    Clin Dermatol 25:109-20. 2007
    ..The success of other approaches to offloading similarly depends on the patients' adherence to the effectiveness of pressure relief...
  46. pmc The RANKL/RANK/OPG signaling pathway mediates medial arterial calcification in diabetic Charcot neuroarthropathy
    Agbor Ndip
    Department of Medicine and Diabetes, Manchester Royal Infirmary, Manchester, UK
    Diabetes 60:2187-96. 2011
    ..This study aimed to investigate the role of RANKL/OPG in MAC in patients with CN...
  47. doi request reprint Remote assessment of diabetic foot ulcers using a novel wound imaging system
    Frank L Bowling
    University of Manchester, Manchester Royal Infirmary, Manchester, UK
    Wound Repair Regen 19:25-30. 2011
    ..g., moistness or exudation. Clinicians gave positive feedback on visual fidelity. This pilot study showed that a clinician viewing only the three-dimensional images could accurately measure and assess a diabetic foot wound remotely...
  48. ncbi request reprint Vibration perception threshold--a valuable assessment of neural dysfunction in people with diabetes
    Adam P Garrow
    Diabetes Foot Clinic, Disablement Services Centre, Withington Hospital, Manchester, UK
    Diabetes Metab Res Rev 22:411-9. 2006
    ..Incorporating VPT testing into clinical practice has the potential to significantly improve the outcomes in patients with DPN, thereby substantially reducing the socio-economic burden of this common and challenging disease...
  49. ncbi request reprint Charcot neuroarthropathy: an unusual case and a review of the literature
    Eleanna V Salgami
    University Department of Medicine, Manchester Royal Infirmary, UK
    Int J Low Extrem Wounds 5:207-12. 2006
    ..Further investigation with magnetic resonance and white cell-labeled imaging revealed osteomyelitis. Below-knee amputation was the only therapeutic option in this hindfoot collapse complicated with osteomyelitis...
  50. doi request reprint Update on the diabetic foot 2012: the 14th biennial Malvern Diabetic Foot Conference, May 9-11, 2012
    Peter Lamont
    Manchester Foot Hospital, Manchester, UK
    Int J Low Extrem Wounds 12:71-5. 2013
    ..The conference has been an excellent platform from which to share new and ongoing research and it will without a doubt improve the treatment of the diabetic foot across the world...
  51. ncbi request reprint Consensus statement on negative pressure wound therapy (V.A.C. Therapy) for the management of diabetic foot wounds
    George Andros
    Diabetic Foot Center, Providence Saint Joseph Medical Center, Burbank, CA, USA
    Ostomy Wound Manage . 2006
    ..A.C. Therapy? (11) How should success in the use of V.A.C. Therapy be defined? (12) How can one combine effective offloading and V.A.C. Therapy?..
  52. ncbi request reprint Evaluation of removable and irremovable cast walkers in the healing of diabetic foot wounds: a randomized controlled trial
    David G Armstrong
    Center for Lower Extremity Ambulatory Research, Dr William M Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, 3333 Green Bay Rd, North Chicago, IL 60064, USA
    Diabetes Care 28:551-4. 2005
    ..The purpose of this study was to evaluate the effectiveness of a removable cast walker (RCW) and an "instant" total contact cast (iTCC) in healing neuropathic diabetic foot ulcerations...
  53. ncbi request reprint Plantar pressure changes using a novel negative pressure wound therapy technique
    David G Armstrong
    Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson, USA
    J Am Podiatr Med Assoc 94:456-60. 2004
    ....
  54. ncbi request reprint Variability in activity may precede diabetic foot ulceration
    David G Armstrong
    Dr William M Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, Chicago, Illinois 60064, USA
    Diabetes Care 27:1980-4. 2004
    ..To evaluate the role of activity in the development of neuropathic foot ulceration in individuals with diabetes...
  55. ncbi request reprint What is the shelf life of physician-mixed antibiotic-impregnated calcium sulfate pellets?
    David G Armstrong
    Department of Surgery, Southern Arizona Veterans Affairs Health Care System, Tucson, AZ 85723, USA
    J Foot Ankle Surg 42:302-4. 2003
    ....
  56. ncbi request reprint Diabetic foot syndrome: evaluating the prevalence and incidence of foot pathology in Mexican Americans and non-Hispanic whites from a diabetes disease management cohort
    Lawrence A Lavery
    Department of Surgery, Diabetex Research Group, Baltimore, Maryland, USA
    Diabetes Care 26:1435-8. 2003
    ..To report the incidence of diabetes-related lower-extremity complications in a cohort of patients enrolled in a diabetes disease management program...
  57. ncbi request reprint Predictive value of foot pressure assessment as part of a population-based diabetes disease management program
    Lawrence A Lavery
    Diabetex Research Group, Baltimore, Maryland, USA
    Diabetes Care 26:1069-73. 2003
    ..In choosing the cut point, we looked for an optimum combination of sensitivity and specificity of plantar pressure to screen for neuropathic ulceration...
  58. ncbi request reprint Ankle equinus deformity and its relationship to high plantar pressure in a large population with diabetes mellitus
    Lawrence A Lavery
    Diabetex Research Group, Baltimore, Maryland, USA
    J Am Podiatr Med Assoc 92:479-82. 2002
    ..Having a high index of suspicion for this deformity and subsequently addressing it through conservative or surgical means may help to reduce the risk of foot ulceration and amputation...
  59. ncbi request reprint Technique for fabrication of an "instant total-contact cast" for treatment of neuropathic diabetic foot ulcers
    David G Armstrong
    Research and Education, Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson 85723, USA
    J Am Podiatr Med Assoc 92:405-8. 2002
    ..In the authors' opinion, this technique addresses many of the disadvantages of the total-contact cast, resulting in an adequate compromise in this aspect of care...
  60. doi request reprint Resource utilization and economic costs of care based on a randomized trial of vacuum-assisted closure therapy in the treatment of diabetic foot wounds
    Jan Apelqvist
    Department of Endocrinology, University Hospital of Malmo, Malmo, Sweden
    Am J Surg 195:782-8. 2008
    ..To evaluate resource utilization and direct economic costs of care for patients treated with negative-pressure wound therapy (NPWT), using the Vacuum-Assisted Closure (V.A.C.) system, compared to standard moist wound therapy (MWT)...
  61. ncbi request reprint Efficacy of multilayered hosiery in reducing in-shoe plantar foot pressure in high-risk patients with diabetes
    Adam P Garrow
    Diabetes Foot Clinic, Disablement Services Centre, Withington Hospital, Cavendish Road, Manchester M20 1LB, UK
    Diabetes Care 28:2001-6. 2005
    ..This study examines the ability of preventive foot care (PFC) socks to reduce plantar foot pressures in a sample of high-risk patients with diabetes...
  62. ncbi request reprint UKPDS 59: hyperglycemia and other potentially modifiable risk factors for peripheral vascular disease in type 2 diabetes
    Amanda I Adler
    Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK
    Diabetes Care 25:894-9. 2002
    ..To determine the role of hyperglycemia in prospective analyses of peripheral vascular disease (PVD) in type 2 diabetes, taking into account other potential risk factors...
  63. ncbi request reprint Does treatment with duloxetine for neuropathic pain impact glycemic control?
    Thomas Hardy
    Eli Lilly, Lilly Corporate Center DC 2138, Indianapolis, IN 46285, USA
    Diabetes Care 30:21-6. 2007
    ..We examined changes in metabolic parameters in clinical trials of duloxetine for diabetic peripheral neuropathic pain (DPNP)...
  64. ncbi request reprint Do US veterans wear appropriately sized shoes?: the Veterans Affairs shoe size selection study
    Brent P Nixon
    Department of Surgery, Southern Arizona Veterans Affairs Medical Center, Tucson, USA
    J Am Podiatr Med Assoc 96:290-2. 2006
    ..This implies that appropriate meticulous screening for shoe-foot mismatches may be useful in reducing the risk of lower-extremity ulceration...
  65. ncbi request reprint Negative pressure wound therapy via vacuum-assisted closure following partial foot amputation: what is the role of wound chronicity?
    David G Armstrong
    Scholl s Center for Lower Extremity Ambulatory Research, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA
    Int Wound J 4:79-86. 2007
    ..These results appear to indicate that wound duration should not deter the clinician from using this modality to treat complex wounds...
  66. ncbi request reprint Evidence-based protocol for diabetic foot ulcers
    Harold Brem
    Department of Surgery, Wound Healing Program, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Plast Reconstr Surg 117:193S-209S; discussion 210S-211S. 2006
    ..Strict adherence to evidence-based protocols as described herein will prevent the majority of these amputations...
  67. ncbi request reprint It's not what you put on, but what you take off: techniques for debriding and off-loading the diabetic foot wound
    David G Armstrong
    Department of Surgery, Dr William M Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA
    Clin Infect Dis 39:S92-9. 2004
    ..Specific debridement and off-loading techniques are discussed, along with available supporting evidence. This includes the use of the "instant" total contact cast, among other modalities...
  68. ncbi request reprint Wound-healing protocols for diabetic foot and pressure ulcers
    Harold Brem
    Wound Healing Program, Angiogenesis and Wound Healing Laboratory, The Mount Sinai Medical Center, New York, NY, USA
    Surg Technol Int 11:85-92. 2003
    ..If this paradigm is followed, most diabetic foot and pressure ulcers are expected to heal...
  69. ncbi request reprint Malignant melanoma misdiagnosed as a diabetic foot ulcer
    Lee C Rogers
    Diabetes Care 30:444-5. 2007
  70. ncbi request reprint Validation of a diabetic foot surgery classification
    David G Armstrong
    Scholl s Center for Lower Extremity Ambulatory Research at Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA
    Int Wound J 3:240-6. 2006
    ..This may assist the surgeon in better identifying risk when determining a rationale for and type of surgery in persons with diabetes...
  71. ncbi request reprint Therapeutic footwear in patients with diabetes
    Peter R Cavanagh
    JAMA 288:1231; author reply 1232-3. 2002
  72. ncbi request reprint Use of tobramycin-impregnated calcium sulphate pellets in addition to oral antibiotics: an alternative treatment to minor amputation in a case of diabetic foot osteomyelitis
    Eleanna V Salgami
    Diabetes Care 30:181-2. 2007
  73. ncbi request reprint Maggot debridement therapy: a primer
    David G Armstrong
    Research and Education, Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson 85723, USA
    J Am Podiatr Med Assoc 92:398-401. 2002
    ..This article describes the use of maggot debridement therapy for intractable wounds of the lower extremity...
  74. ncbi request reprint Whither clinical research in diabetic sensorimotor peripheral neuropathy? Problems of end point selection for clinical trials
    Andrew J M Boulton
    Diabetes Care 30:2752-3. 2007
  75. ncbi request reprint Outcomes of subatmospheric pressure dressing therapy on wounds of the diabetic foot
    David G Armstrong
    Department of Surgery, Southern Arizona Veterans Affairs Medical Center, Tucson, Ariz, USA
    Ostomy Wound Manage 48:64-8. 2002
    ....
  76. ncbi request reprint Activity patterns of patients with diabetic foot ulceration: patients with active ulceration may not adhere to a standard pressure off-loading regimen
    David G Armstrong
    Department of Surgery, Southern Arizona Veterans Affairs Medical Center, Tucson, Arizona 85723, USA
    Diabetes Care 26:2595-7. 2003
    ..To evaluate the activity of patients with diabetic foot ulcerations and their adherence to their pressure off-loading device...
  77. ncbi request reprint Quality of life in CAPD, transplant, and chronic renal failure patients with diabetes
    Theofanis Apostolou
    Evangelismos General Hospital, Athens, Greece
    Ren Fail 29:189-97. 2007
    ..Although quality of life (QoL) is an important outcome measure, there are few studies of QoL in diabetic patients. We performed a cross-sectional study to assess QoL in such patients comparable for age, sex, and co-morbidity...
  78. ncbi request reprint Negative pressure wound therapy in treatment of diabetic foot wounds: a marriage of modalities
    David G Armstrong
    Department of Surgery, Podiatry Section, Tucson Veterans Administration Hospital, Ariz, USA
    Ostomy Wound Manage 50:9-12. 2004
  79. ncbi request reprint Use of a maggot motility index to evaluate survival of therapeutic larvae
    Anthony Rosales
    Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson, USA
    J Am Podiatr Med Assoc 94:353-5. 2004
    ..There were significant differences in motility between refrigerated and nonrefrigerated larvae immediately after baseline until day 8. Larvae are more practical for repeated clinical use if kept refrigerated between applications...
  80. ncbi request reprint Protocol for treatment of diabetic foot ulcers
    Harold Brem
    Department of Surgery, Columbia University College of Physicians and Surgeons, 5141 Broadway, New York, New York 10034, USA
    Am J Surg 187:1S-10S. 2004
    ....
  81. ncbi request reprint Corneal nerve tortuosity in diabetic patients with neuropathy
    Panagiotis Kallinikos
    Eurolens Research, Department of Optometry and Neuroscience, University of Manchester Institute of Science and Technology, Manchester, United Kingdom
    Invest Ophthalmol Vis Sci 45:418-22. 2004
    ..The purpose of this study was to define alterations in the tortuosity of corneal nerve fibers in relation to age, duration of diabetes, glycemic control, and neuropathic severity...
  82. ncbi request reprint Clinical efficacy of the first metatarsophalangeal joint arthroplasty as a curative procedure for hallux interphalangeal joint wounds in patients with diabetes
    David G Armstrong
    Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson, Arizona, USA
    Diabetes Care 26:3284-7. 2003
    ..To evaluate the safety and efficacy of first metatarsophalangeal joint arthroplasty compared with standard, nonsurgical management of wounds at the plantar hallux interphalangeal joint in patients with diabetes...
  83. ncbi request reprint 2003 William J. Stickel Silver Award. Skin temperatures as a one-time screening tool do not predict future diabetic foot complications
    David G Armstrong
    Diabetex Research Group, Baltimore, MD, USA
    J Am Podiatr Med Assoc 93:443-7. 2003
    ..Regular assessment of skin temperatures, using the contralateral site as a physiologic control, may be a better use of this technology...
  84. ncbi request reprint Chronic inflammatory demyelinating polyneuropathy and diabetes
    Andrew J M Boulton
    Curr Diab Rep 3:437-8. 2003
  85. ncbi request reprint Trials in neuropathic diabetic foot ulceration: time for a paradigm shift?
    Andrew J M Boulton
    Diabetes Care 26:2689-90. 2003
  86. ncbi request reprint The Biogun: A novel way of eradicating methicillin-resistant Staphylococcus aureus colonization in diabetic foot ulcers
    Cuong Nguyen Dang
    Diabetes Care 29:1176. 2006