John D Boughter

Summary

Affiliation: University of Tennessee
Country: USA

Publications

  1. pmc Behavioral genetics and taste
    John D Boughter
    Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    BMC Neurosci 8:S3. 2007
  2. ncbi request reprint C57BL/6J and DBA/2J mice vary in lick rate and ingestive microstructure
    J D Boughter
    Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Genes Brain Behav 6:619-27. 2007
  3. pmc Inbred mouse strains C57BL/6J and DBA/2J vary in sensitivity to a subset of bitter stimuli
    John D Boughter
    Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    BMC Genet 6:36. 2005
  4. pmc Genetic control of a central pattern generator: rhythmic oromotor movement in mice is controlled by a major locus near Atp1a2
    John D Boughter
    Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
    PLoS ONE 7:e38169. 2012
  5. pmc Sweet-bitter and umami-bitter taste interactions in single parabrachial neurons in C57BL/6J mice
    Kenichi Tokita
    Dept of Anatomy and Neurobiology, Univ of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Neurophysiol 108:2179-90. 2012
  6. ncbi request reprint Histopathological and postoperative behavioral comparison of rodent oral tongue resection: fiber-enabled CO2 laser versus electrocautery
    Courtney B Shires
    Department of Otolaryngology, Head and Neck Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Otolaryngol Head Neck Surg 147:716-21. 2012
  7. ncbi request reprint Taste sensitivities to PROP and PTC vary independently in mice
    Theodore M Nelson
    Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201 1509, USA
    Chem Senses 28:695-704. 2003
  8. pmc Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice
    Theodore M Nelson
    Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    BMC Genet 6:32. 2005
  9. pmc Variation in nicotine consumption in inbred mice is not linked to orosensory ability
    A Rebecca Glatt
    Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Chem Senses 34:27-35. 2009
  10. doi request reprint Gastric bypass surgery in rats produces weight loss modeling after human gastric bypass
    David S Tichansky
    Section of Minimally Invasive Surgery, Department of Surgery, College of Medicine, University of Tennessee Health Science Center, 910 Madison Ave, Suite 208, Memphis, TN, 38163, USA
    Obes Surg 18:1246-50. 2008

Research Grants

  1. Bitter Taste: Physiology and Behavior
    JOHN BOUGHTER; Fiscal Year: 2004
  2. SENSORY CODING IN TASTE
    JOHN BOUGHTER; Fiscal Year: 2007
  3. Genetic Dissection of a Motor Central Pattern Generator
    JOHN BOUGHTER; Fiscal Year: 2007

Detail Information

Publications22

  1. pmc Behavioral genetics and taste
    John D Boughter
    Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    BMC Neurosci 8:S3. 2007
    ..Recent advances in development of genomic resources make behavioral genetics a powerful approach for understanding mechanisms of taste...
  2. ncbi request reprint C57BL/6J and DBA/2J mice vary in lick rate and ingestive microstructure
    J D Boughter
    Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Genes Brain Behav 6:619-27. 2007
    ..Overall, it appeared that D2 mice licked more efficiently, ingesting more rapidly during excursions to the spout that were fewer and farther between...
  3. pmc Inbred mouse strains C57BL/6J and DBA/2J vary in sensitivity to a subset of bitter stimuli
    John D Boughter
    Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    BMC Genet 6:36. 2005
    ..Here, we used a taste-salient brief-access procedure to measure taste sensitivity to eight stimuli characterized as bitter or aversive in C57BL/6J (B6) and DBA/2J (D2) mice...
  4. pmc Genetic control of a central pattern generator: rhythmic oromotor movement in mice is controlled by a major locus near Atp1a2
    John D Boughter
    Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
    PLoS ONE 7:e38169. 2012
    ....
  5. pmc Sweet-bitter and umami-bitter taste interactions in single parabrachial neurons in C57BL/6J mice
    Kenichi Tokita
    Dept of Anatomy and Neurobiology, Univ of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Neurophysiol 108:2179-90. 2012
    ..Although a peripheral basis for QHCl suppression has been demonstrated, our results suggest that convergence in the PbN plays a role in shaping responses to taste mixtures...
  6. ncbi request reprint Histopathological and postoperative behavioral comparison of rodent oral tongue resection: fiber-enabled CO2 laser versus electrocautery
    Courtney B Shires
    Department of Otolaryngology, Head and Neck Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Otolaryngol Head Neck Surg 147:716-21. 2012
    ....
  7. ncbi request reprint Taste sensitivities to PROP and PTC vary independently in mice
    Theodore M Nelson
    Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201 1509, USA
    Chem Senses 28:695-704. 2003
    ..Most strikingly, these results demonstrate that in mice, unlike in humans, PTC and PROP taste sensitivities vary independently, thereby suggesting a subtle functional diversity of bitter-taste mechanisms across mammalian species...
  8. pmc Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice
    Theodore M Nelson
    Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    BMC Genet 6:32. 2005
    ..However, there is evidence for both receptor-dependent and -independent transduction mechanisms for a number of bitter stimuli, including quinine hydrochloride (QHCl) and denatonium benzoate (DB)...
  9. pmc Variation in nicotine consumption in inbred mice is not linked to orosensory ability
    A Rebecca Glatt
    Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Chem Senses 34:27-35. 2009
    ..This study provides evidence that variation in intake level of nicotine is likely not due to differences in taste or trigeminal sensitivity but likely due to postingestive factors...
  10. doi request reprint Gastric bypass surgery in rats produces weight loss modeling after human gastric bypass
    David S Tichansky
    Section of Minimally Invasive Surgery, Department of Surgery, College of Medicine, University of Tennessee Health Science Center, 910 Madison Ave, Suite 208, Memphis, TN, 38163, USA
    Obes Surg 18:1246-50. 2008
    ..The study of the mechanisms of weight loss after bariatric surgery requires an animal model that mimics the human procedure and subsequent weight loss. A rat model eliminates the cognitive efforts associated with human weight loss and gain...
  11. pmc Genetic analysis of tongue size and taste papillae number and size in recombinant inbred strains of mice
    David J Reiner
    Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, College of Medicine, 855 Monroe Avenue, Memphis, TN 38163, USA
    Chem Senses 33:693-707. 2008
    ..This study is an important first step in identifying genetic factors underlying tongue size, papillae size, and papillae number using QTL analysis...
  12. doi request reprint Ultrasound-guided fine-needle aspiration of the tongue base: a cadaver feasibility study
    Ryan K Meacham
    University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Otolaryngol Head Neck Surg 147:864-9. 2012
    ..After reasonable success of injecting dye into cadaver tongue bases, the authors conclude that there appears to be a future clinical role for ultrasound-guided fine-needle aspiration of the tongue base for tongue base lesions...
  13. pmc Gustatory neural responses to umami stimuli in the parabrachial nucleus of C57BL/6J mice
    Kenichi Tokita
    Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Neurophysiol 107:1545-55. 2012
    ..The distribution pattern of reconstructed recording sites of specific neuron types suggested chemotopic organization in the PbN...
  14. doi request reprint Cerebellar cortical output encodes temporal aspects of rhythmic licking movements and is necessary for normal licking frequency
    Jeri L Bryant
    Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, USA
    Eur J Neurosci 32:41-52. 2010
    ....
  15. doi request reprint Effects of sensory or motor nerve deafferentation on oromotor function in mice
    Courtney B Shires
    University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Otolaryngol Head Neck Surg 144:915-20. 2011
    ..To investigate the effect of sensory or motor nerve damage to the tongue using a mouse model...
  16. doi request reprint Sphenopalatine artery ligation: a cadaver anatomic study
    Courtney B Shires
    Department of Otolaryngology, University of Tennessee Health Science Center, Memphis, TN, USA
    Otolaryngol Head Neck Surg 145:494-7. 2011
    ..To clarify endoscopic anatomy of the sphenopalatine artery (SPA) in relation to intranasal endoscopic landmarks using a human cadaver model and to simplify the surgical approach to SPA ligation...
  17. ncbi request reprint Taste change after laparoscopic Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding
    David S Tichansky
    Section of Minimally Invasive Surgery, Department of Surgery, University of Tennessee College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Surg Obes Relat Dis 2:440-4. 2006
    ..Many patients have described changes in taste perception after weight loss surgery. Our hypothesis was that patients develop postoperative changes in taste that vary by bariatric procedure...
  18. pmc A low-cost solution to measure mouse licking in an electrophysiological setup with a standard analog-to-digital converter
    Abdallah Hayar
    Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, 855 Monroe Avenue, Suite 515, Memphis, TN 38163, USA
    J Neurosci Methods 153:203-7. 2006
    ..This method does not produce any significant electrical artifacts and can be combined with electrophysiological measurements of single unit activity from neurons involved in the control of the licking behavior...
  19. ncbi request reprint The contribution of taste bud populations to bitter avoidance in mouse strains differentially sensitive to sucrose octa-acetate and quinine
    Steven J St John
    Department of Psychology, Reed College, Portland, OR 97202, USA
    Chem Senses 29:775-87. 2004
    ..These findings are discussed with regard to the distribution in the oral cavity of putative taste receptors for quinine and SOA and the peripheral organization of bitter taste...
  20. ncbi request reprint Phenylthiocarbamide produces conditioned taste aversions in mice
    Steven J St John
    Department of Psychology, Reed College, Portland, OR 97202, USA
    Chem Senses 30:377-82. 2005
    ..We conclude that PTC can cause a conditioned taste aversion and discuss the importance of considering toxic effects of aversive tastants when analyzing behavioral strain differences...
  21. ncbi request reprint Taste transduction: appetizing times in gustation
    Timothy A Gilbertson
    Department of Biology, Utah State University, Logan 84322 5305, USA
    Neuroreport 14:905-11. 2003
    ..This basic information will be critical to answer longstanding questions regarding the coding of taste information and may help elucidate the role of the taste system in the control of food intake...
  22. ncbi request reprint A brief-access test for bitter taste in mice
    John D Boughter
    Department of Anatomy and Neurobiology and Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201 1509, USA
    Chem Senses 27:133-42. 2002
    ..The brief-access test is a suitable assay for bitter taste function in mice because it minimizes possible post-ingestive influences on taste...

Research Grants5

  1. Bitter Taste: Physiology and Behavior
    JOHN BOUGHTER; Fiscal Year: 2004
    ..By examining these strain differences in receptor cell function, these studies should help to link ongoing molecular advances to the neural mechanisms underlying bitter taste function. ..
  2. SENSORY CODING IN TASTE
    JOHN BOUGHTER; Fiscal Year: 2007
    ..These experiments test the hypothesis that there are differences in voltage- activated conductances and cell morphology between neurons projecting to the VPMpc and the CeA. ..
  3. Genetic Dissection of a Motor Central Pattern Generator
    JOHN BOUGHTER; Fiscal Year: 2007
    ..Comparison of the genes and mechanisms underlying stereotyped repetitive movements versus plastic behaviors will be a source of information relevant for a number of human CMS disorders involving abnormal repetitive movements. ..