Laura N Borodinsky

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Activity-dependent homeostatic specification of transmitter expression in embryonic neurons
    Laura N Borodinsky
    Neurobiology Section, Division of Biological Sciences and Center for Molecular Genetics, UCSD, La Jolla, California 92093 0357, USA
    Nature 429:523-30. 2004
  2. ncbi request reprint Second messenger pas de deux: the coordinated dance between calcium and cAMP
    Laura N Borodinsky
    Neurobiology Section, Kavli Institute for Brain and Mind, University of California, San Diego, La Jolla, CA 92093, USA
    Sci STKE 2006:pe22. 2006
  3. ncbi request reprint Orchestrating neuronal differentiation: patterns of Ca2+ spikes specify transmitter choice
    Nicholas C Spitzer
    Neurobiology Section and Center for Molecular Genetics, Division of Biological Sciences, UCSD, La Jolla, CA 92093, USA
    Trends Neurosci 27:415-21. 2004
  4. ncbi request reprint Homeostatic activity-dependent paradigm for neurotransmitter specification
    Nicholas C Spitzer
    Neurobiology Section, Division of Biological Sciences and Center for Molecular Genetics, UCSD, La Jolla, CA 92093 0357, USA
    Cell Calcium 37:417-23. 2005
  5. pmc Activity-dependent neurotransmitter-receptor matching at the neuromuscular junction
    Laura N Borodinsky
    Neurobiology Section, Division of Biological Sciences and Center for Molecular Genetics, Kavli Institute for Brain and Mind, University of California at San Diego, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 104:335-40. 2007
  6. doi request reprint Imaging and manipulating calcium transients in developing Xenopus spinal neurons
    Nicholas C Spitzer
    Neurobiology Section and Center for Molecular Genetics, Kavli Institute for Brain and Mind, Division of Biological Sciences, University of California at San Diego, La Jolla, California 92093, USA
    Cold Spring Harb Protoc 2013:653-64. 2013
  7. pmc Implications of activity-dependent neurotransmitter-receptor matching
    Nicholas C Spitzer
    Neurobiology Section, Division of Biological Sciences, Center for Molecular Genetics, Kavli Institute for Brain and Mind, UCSD, La Jolla, CA 92093, USA
    Philos Trans R Soc Lond B Biol Sci 363:1393-9. 2008
  8. ncbi request reprint Contribution of Ca2+ calmodulin-dependent protein kinase II and mitogen-activated protein kinase kinase to neural activity-induced neurite outgrowth and survival of cerebellar granule cells
    Laura N Borodinsky
    Instituto de Investigaciones Farmacologicas, CONICET, FCEyN, UBA, Buenos Aires, Argentina
    J Neurochem 80:1062-70. 2002
  9. ncbi request reprint GABA-induced neurite outgrowth of cerebellar granule cells is mediated by GABA(A) receptor activation, calcium influx and CaMKII and erk1/2 pathways
    Laura N Borodinsky
    Instituto de Investigaciones Farmacológicas CONICET, Buenos Aires, Argentina
    J Neurochem 84:1411-20. 2003
  10. ncbi request reprint Neurobiology: how fast can you go?
    Laura N Borodinsky
    Nature 440:158-9. 2006

Detail Information

Publications10

  1. ncbi request reprint Activity-dependent homeostatic specification of transmitter expression in embryonic neurons
    Laura N Borodinsky
    Neurobiology Section, Division of Biological Sciences and Center for Molecular Genetics, UCSD, La Jolla, California 92093 0357, USA
    Nature 429:523-30. 2004
    ..The results identify a new role of patterned activity in development of the central nervous system...
  2. ncbi request reprint Second messenger pas de deux: the coordinated dance between calcium and cAMP
    Laura N Borodinsky
    Neurobiology Section, Kavli Institute for Brain and Mind, University of California, San Diego, La Jolla, CA 92093, USA
    Sci STKE 2006:pe22. 2006
    ..Second messenger reporters are now available to track multiple players and so provide a dynamic picture of signaling networks...
  3. ncbi request reprint Orchestrating neuronal differentiation: patterns of Ca2+ spikes specify transmitter choice
    Nicholas C Spitzer
    Neurobiology Section and Center for Molecular Genetics, Division of Biological Sciences, UCSD, La Jolla, CA 92093, USA
    Trends Neurosci 27:415-21. 2004
    ..changes in presynaptic transmitter expression pose a matching problem: are there corresponding changes in postsynaptic transmitter receptor expression, or are axons rerouted to novel targets with which functional synapses can be formed?..
  4. ncbi request reprint Homeostatic activity-dependent paradigm for neurotransmitter specification
    Nicholas C Spitzer
    Neurobiology Section, Division of Biological Sciences and Center for Molecular Genetics, UCSD, La Jolla, CA 92093 0357, USA
    Cell Calcium 37:417-23. 2005
    ....
  5. pmc Activity-dependent neurotransmitter-receptor matching at the neuromuscular junction
    Laura N Borodinsky
    Neurobiology Section, Division of Biological Sciences and Center for Molecular Genetics, Kavli Institute for Brain and Mind, University of California at San Diego, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 104:335-40. 2007
    ..In these cases, glutamatergic, GABAergic, and glycinergic synaptic currents are recorded from muscle cells, demonstrating that activity regulates matching of transmitters and their receptors in the assembly of functional synapses...
  6. doi request reprint Imaging and manipulating calcium transients in developing Xenopus spinal neurons
    Nicholas C Spitzer
    Neurobiology Section and Center for Molecular Genetics, Kavli Institute for Brain and Mind, Division of Biological Sciences, University of California at San Diego, La Jolla, California 92093, USA
    Cold Spring Harb Protoc 2013:653-64. 2013
    ....
  7. pmc Implications of activity-dependent neurotransmitter-receptor matching
    Nicholas C Spitzer
    Neurobiology Section, Division of Biological Sciences, Center for Molecular Genetics, Kavli Institute for Brain and Mind, UCSD, La Jolla, CA 92093, USA
    Philos Trans R Soc Lond B Biol Sci 363:1393-9. 2008
    ..Matching of postsynaptic receptor expression with the novel expression of transmitters ensues. These findings have intriguing implications for development, mature function and evolution of the nervous system...
  8. ncbi request reprint Contribution of Ca2+ calmodulin-dependent protein kinase II and mitogen-activated protein kinase kinase to neural activity-induced neurite outgrowth and survival of cerebellar granule cells
    Laura N Borodinsky
    Instituto de Investigaciones Farmacologicas, CONICET, FCEyN, UBA, Buenos Aires, Argentina
    J Neurochem 80:1062-70. 2002
    ..Ca2+ calmodulin-dependent protein kinase II activation determines the growth of neurites and the development of neuronal complexity...
  9. ncbi request reprint GABA-induced neurite outgrowth of cerebellar granule cells is mediated by GABA(A) receptor activation, calcium influx and CaMKII and erk1/2 pathways
    Laura N Borodinsky
    Instituto de Investigaciones Farmacológicas CONICET, Buenos Aires, Argentina
    J Neurochem 84:1411-20. 2003
    ..These data demonstrate that GABA exerts a stimulatory role on cerebellar granule cell neuritogenesis through calcium influx and activation of calcium-dependent kinases...
  10. ncbi request reprint Neurobiology: how fast can you go?
    Laura N Borodinsky
    Nature 440:158-9. 2006