S B Boppana

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi Congenital cytomegalovirus infection: association between virus burden in infancy and hearing loss
    Suresh B Boppana
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    J Pediatr 146:817-23. 2005
  2. ncbi Congenital cytomegalovirus (CMV) infection and hearing deficit
    Karen B Fowler
    Departments of Pediatrics, Epidemiology and Maternal and Child Health, University of Alabama at Birmingham, USA
    J Clin Virol 35:226-31. 2006
  3. ncbi Symptomatic congenital cytomegalovirus infection in infants born to mothers with preexisting immunity to cytomegalovirus
    S B Boppana
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Pediatrics 104:55-60. 1999
  4. ncbi Intrauterine transmission of cytomegalovirus to infants of women with preconceptional immunity
    S B Boppana
    Department of Pediatrics, University of Alabama at Birmingham, 35233, USA
    N Engl J Med 344:1366-71. 2001
  5. ncbi Saliva polymerase-chain-reaction assay for cytomegalovirus screening in newborns
    Suresh B Boppana
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    N Engl J Med 364:2111-8. 2011
  6. ncbi Dried blood spot real-time polymerase chain reaction assays to screen newborns for congenital cytomegalovirus infection
    Suresh B Boppana
    UAB Department of Pediatrics, CHB 114, 1600 Sixth Ave S, Birmingham, AL 35233, USA
    JAMA 303:1375-82. 2010
  7. ncbi Overview of the diagnosis of cytomegalovirus infection
    S A Ross
    Departments of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Infect Disord Drug Targets 11:466-74. 2011
  8. ncbi Cytomegalovirus reinfections in healthy seroimmune women
    Shannon A Ross
    Departments of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA
    J Infect Dis 201:386-9. 2010
  9. ncbi Cytomegalovirus blood viral load and hearing loss in young children with congenital infection
    Shannon A Ross
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Pediatr Infect Dis J 28:588-92. 2009
  10. ncbi Enzyme-linked immunosorbent assay method for detection of cytomegalovirus strain-specific antibody responses
    Zdenek Novak
    Department of Pediatrics, The University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Clin Vaccine Immunol 16:288-90. 2009

Research Grants

  1. CONGENITAL CMV INFECTION IN OFFSPRING OF IMMUNE MOTHERS
    Suresh Boppana; Fiscal Year: 2005

Detail Information

Publications18

  1. ncbi Congenital cytomegalovirus infection: association between virus burden in infancy and hearing loss
    Suresh B Boppana
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    J Pediatr 146:817-23. 2005
    ..To determine the relationship between the virus burden in infancy and hearing loss in congenital CMV infection...
  2. ncbi Congenital cytomegalovirus (CMV) infection and hearing deficit
    Karen B Fowler
    Departments of Pediatrics, Epidemiology and Maternal and Child Health, University of Alabama at Birmingham, USA
    J Clin Virol 35:226-31. 2006
    ..Studies over the past four decades have further described the relationship between congenital CMV infection and SNHL in children...
  3. ncbi Symptomatic congenital cytomegalovirus infection in infants born to mothers with preexisting immunity to cytomegalovirus
    S B Boppana
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Pediatrics 104:55-60. 1999
    ..To determine the frequency of symptomatic congenital cytomegalovirus (CMV) infection in the offspring of women with a recurrent maternal CMV infection and to characterize the demographic and newborn findings...
  4. ncbi Intrauterine transmission of cytomegalovirus to infants of women with preconceptional immunity
    S B Boppana
    Department of Pediatrics, University of Alabama at Birmingham, 35233, USA
    N Engl J Med 344:1366-71. 2001
    ..Whether congenital CMV infection in the offspring of women who are seropositive for CMV can occur after maternal reinfection with a different strain of CMV is unknown...
  5. ncbi Saliva polymerase-chain-reaction assay for cytomegalovirus screening in newborns
    Suresh B Boppana
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    N Engl J Med 364:2111-8. 2011
    ..Two alternatives--real-time polymerase-chain-reaction (PCR)-based testing of a liquid-saliva or dried-saliva specimen obtained at birth--have been developed...
  6. ncbi Dried blood spot real-time polymerase chain reaction assays to screen newborns for congenital cytomegalovirus infection
    Suresh B Boppana
    UAB Department of Pediatrics, CHB 114, 1600 Sixth Ave S, Birmingham, AL 35233, USA
    JAMA 303:1375-82. 2010
    ..Since dried blood spots (DBS) are routinely collected for metabolic screening from all newborns in the United States, there has been interest in using DBS polymerase chain reaction (PCR)-based methods for newborn CMV screening...
  7. ncbi Overview of the diagnosis of cytomegalovirus infection
    S A Ross
    Departments of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Infect Disord Drug Targets 11:466-74. 2011
    ..However, lack of standardized real-time PCR protocols hinders the comparison of data from different centers and the development of uniform guidelines for the management of invasive CMV infections in immunocompromised individuals...
  8. ncbi Cytomegalovirus reinfections in healthy seroimmune women
    Shannon A Ross
    Departments of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA
    J Infect Dis 201:386-9. 2010
    ..None of the exposure factors were associated with CMV reinfection. Women with antibodies against at least 1 of the 4 antigens at baseline had a 63% decreased risk of reinfection, suggesting a protective role for strain-specific immunity...
  9. ncbi Cytomegalovirus blood viral load and hearing loss in young children with congenital infection
    Shannon A Ross
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Pediatr Infect Dis J 28:588-92. 2009
    ..This study was designed to determine whether elevated viral load in infants and young children is associated with congenital cytomegalovirus (CMV)-related hearing loss...
  10. ncbi Enzyme-linked immunosorbent assay method for detection of cytomegalovirus strain-specific antibody responses
    Zdenek Novak
    Department of Pediatrics, The University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Clin Vaccine Immunol 16:288-90. 2009
    ..This assay is useful for the detection of serologic responses to CMV strains and the identification of CMV reinfections...
  11. ncbi Cytomegalovirus strain diversity in seropositive women
    Zdenek Novak
    Department of Pediatrics, The University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Clin Microbiol 46:882-6. 2008
    ..The results also showed that the RFLP technique might not be sufficiently sensitive to detect all of the genomic variants present in a sample...
  12. ncbi Hearing loss in children with congenital cytomegalovirus infection born to mothers with preexisting immunity
    Shannon A Ross
    Department of Pediatrics, University of Alabama at Birmingham, 35233, USA
    J Pediatr 148:332-6. 2006
    ..To define hearing outcomes in children with congenital cytomegalovirus (CMV) infection born to mothers with non-primary CMV infection...
  13. ncbi Congenital cytomegalovirus infection following first trimester maternal infection: symptoms at birth and outcome
    Robert F Pass
    Department of Pediatrics, University of Alabama at Birmingham, USA
    J Clin Virol 35:216-20. 2006
    ..The relationship between gestational age at time of maternal cytomegalovirus (CMV) infection and outcome of fetal infection is not well defined because the timing of maternal infection is usually not known...
  14. ncbi Congenital cytomegalovirus infection: outcome and diagnosis
    Shannon A Ross
    Department of Pediatrics, The University of Alabama at Birmingham, AL 35233, USA
    Semin Pediatr Infect Dis 16:44-9. 2005
    ..However, more work must be done to standardize and validate these methods before they can be used routinely in establishing the diagnosis of congenital CMV infection...
  15. ncbi Cytomegalovirus viruria and DNAemia in healthy seropositive women
    Nitin Arora
    Department of Pediatrics, University of Alabama at Birmingham, Alabama 35233, USA
    J Infect Dis 202:1800-3. 2010
    ..In young seropositive women, CMV DNAemia and viruria are common, which suggests that naturally acquired immunity to CMV does not alter shedding patterns...
  16. ncbi Recognition of human cytomegalovirus gene products by HCMV-specific cytotoxic T cells
    S B Boppana
    Department of Pediatrics, University of Alabama at Birmingham 35233, USA
    Virology 222:293-6. 1996
    ..Characterization of the HCMV-specific CTL clones from two donors revealed that the majority of clones lysed targets expressing pp65 and that none of the clones recognized other HCMV proteins...
  17. ncbi Predictors of hearing loss in children with symptomatic congenital cytomegalovirus infection
    Lisa B Rivera
    Department of Pediatrics, University of Alabama School of Medicine, Birmingham, Alabama 35233, USA
    Pediatrics 110:762-7. 2002
    ..However, it was not possible to identify factors that are independently predictive of the development of progressive hearing loss...
  18. ncbi Congenital cytomegalovirus infection in a highly seropositive semi-urban population in India
    Lalit Dar
    Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India
    Pediatr Infect Dis J 27:841-3. 2008
    ..All 9 (2.1%) CMV positive infants were born to mothers who were CMV seropositive at the first antenatal visit. One child had hepatosplenomegaly at birth and another child had mild unilateral hearing loss at 4 months of age...

Research Grants8

  1. CONGENITAL CMV INFECTION IN OFFSPRING OF IMMUNE MOTHERS
    Suresh Boppana; Fiscal Year: 2005
    ....