S Y Bookheimer

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Thickness in entorhinal and subicular cortex predicts episodic memory decline in mild cognitive impairment
    A C Burggren
    Center for Cognitive Neurosciences, Semel Resnick Institute, University of California, 760 Westwood Plaza No 17 369C, Los Angeles, CA 90095 1759, USA
    Int J Alzheimers Dis 2011:956053. 2011
  2. pmc Abnormal social reward processing in autism as indexed by pupillary responses to happy faces
    Leigh Sepeta
    Department of Psychology, University of California, Los Angeles, CA, 90095, USA
    J Neurodev Disord 4:17. 2012
  3. ncbi Brain imaging in FAS: commentary on the article by Malisza et al
    Susan Y Bookheimer
    Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA 90095, USA
    Pediatr Res 58:1148-9. 2005
  4. pmc APOE-4 genotype and neurophysiological vulnerability to Alzheimer's and cognitive aging
    Susan Bookheimer
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, CA 90095, USA
    Annu Rev Clin Psychol 5:343-62. 2009
  5. pmc Frontal contributions to face processing differences in autism: evidence from fMRI of inverted face processing
    Susan Y Bookheimer
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA
    J Int Neuropsychol Soc 14:922-32. 2008
  6. ncbi Pre-surgical language mapping with functional magnetic resonance imaging
    Susan Bookheimer
    Center for Cognitive Neurosciences, Semel Institute, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA
    Neuropsychol Rev 17:145-55. 2007
  7. ncbi Methodological issues in pediatric neuroimaging
    S Y Bookheimer
    Ahmanson Lovelace Brain Mapping Center, UCLA School of Medicine, Los Angeles, California, 90095, USA
    Ment Retard Dev Disabil Res Rev 6:161-5. 2000
  8. ncbi Functional MRI in children with epilepsy
    S Y Bookheimer
    Division of Brain Mapping, University of California, Los Angeles, CA, USA
    Dev Neurosci 21:191-9. 1999
  9. ncbi Functional MRI of language: new approaches to understanding the cortical organization of semantic processing
    Susan Bookheimer
    Brain Mapping Center, UCLA School of Medicine, 90095, USA
    Annu Rev Neurosci 25:151-88. 2002
  10. pmc Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
    G W Small
    Center on Aging and Department of Psychiatry and Biobehavioral Sciences, Neuropsychiatric Institute, 760 Westwood Plaza, Los Angeles, CA 90024, USA
    Proc Natl Acad Sci U S A 97:6037-42. 2000

Detail Information

Publications80

  1. pmc Thickness in entorhinal and subicular cortex predicts episodic memory decline in mild cognitive impairment
    A C Burggren
    Center for Cognitive Neurosciences, Semel Resnick Institute, University of California, 760 Westwood Plaza No 17 369C, Los Angeles, CA 90095 1759, USA
    Int J Alzheimers Dis 2011:956053. 2011
    ..Given the MTL's involvement in early stages of neurodegeneration in AD, clarifying the relationship of these brain regions and the link to resultant cognitive decline is critical in understanding disease progression...
  2. pmc Abnormal social reward processing in autism as indexed by pupillary responses to happy faces
    Leigh Sepeta
    Department of Psychology, University of California, Los Angeles, CA, 90095, USA
    J Neurodev Disord 4:17. 2012
    ..abstract:..
  3. ncbi Brain imaging in FAS: commentary on the article by Malisza et al
    Susan Y Bookheimer
    Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA 90095, USA
    Pediatr Res 58:1148-9. 2005
  4. pmc APOE-4 genotype and neurophysiological vulnerability to Alzheimer's and cognitive aging
    Susan Bookheimer
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, CA 90095, USA
    Annu Rev Clin Psychol 5:343-62. 2009
    ..This review examines the most recent data on brain changes in genetic risk for AD and discusses the benefits and potential risks of detecting individuals at risk...
  5. pmc Frontal contributions to face processing differences in autism: evidence from fMRI of inverted face processing
    Susan Y Bookheimer
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA
    J Int Neuropsychol Soc 14:922-32. 2008
    ..Our results are consistent with other recent studies implicating frontal and limbic dysfunction during face processing in autism...
  6. ncbi Pre-surgical language mapping with functional magnetic resonance imaging
    Susan Bookheimer
    Center for Cognitive Neurosciences, Semel Institute, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA
    Neuropsychol Rev 17:145-55. 2007
    ..Each disorder presents unique challenges to language mapping. Specific case studies are presented highlighting the both the potential benefits of preclinical fMRI for language mapping as well as the potential risks and pitfalls...
  7. ncbi Methodological issues in pediatric neuroimaging
    S Y Bookheimer
    Ahmanson Lovelace Brain Mapping Center, UCLA School of Medicine, Los Angeles, California, 90095, USA
    Ment Retard Dev Disabil Res Rev 6:161-5. 2000
    ..A variety of technological, experimental, and practical difficulties are amplified when imaging children. This paper reviews some of the more challenging theoretical and practical concerns and provides suggestions for their management...
  8. ncbi Functional MRI in children with epilepsy
    S Y Bookheimer
    Division of Brain Mapping, University of California, Los Angeles, CA, USA
    Dev Neurosci 21:191-9. 1999
    ..This article presents some of the current methods for brain mapping in children as well as early results using fMRI for language mapping in pediatric epilepsy...
  9. ncbi Functional MRI of language: new approaches to understanding the cortical organization of semantic processing
    Susan Bookheimer
    Brain Mapping Center, UCLA School of Medicine, 90095, USA
    Annu Rev Neurosci 25:151-88. 2002
    ..Together, these lines of research broaden our understanding of how the brain stores, retrieves, and makes sense of semantic information, and they challenge some commonly held notions of functional modularity in the language system...
  10. pmc Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
    G W Small
    Center on Aging and Department of Psychiatry and Biobehavioral Sciences, Neuropsychiatric Institute, 760 Westwood Plaza, Los Angeles, CA 90024, USA
    Proc Natl Acad Sci U S A 97:6037-42. 2000
    ..These results indicate that the combination of cerebral metabolic rates and genetic risk factors provides a means for preclinical AD detection that will assist in response monitoring during experimental treatments...
  11. pmc Altered frontal-parietal functioning during verbal working memory in children and adolescents with heavy prenatal alcohol exposure
    Elizabeth D O'Hare
    Department of Neurology, University of California, Los Angeles, CA, USA
    Hum Brain Mapp 30:3200-8. 2009
    ..These findings may suggest that frontal-parietal processing during verbal WM is less efficient in alcohol-exposed individuals...
  12. ncbi Assessment of dementia risk in aging adults using both FDG-PET and FDDNP-PET imaging
    L M Ercoli
    Department of Psychiatry and Biobehavioral Sciences and Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA
    Int J Geriatr Psychiatry 27:1017-27. 2012
    ..In this follow-up investigation, we compared 2-deoxy-2-[F-18]fluoro- d-glucose (FDG)-PET cerebral metabolic patterns in the three FDDNP-PET binding subgroups...
  13. ncbi Neural correlates of facial affect processing in children and adolescents with autism spectrum disorder
    A Ting Wang
    Department of Psychology, UCLA, Los Angeles, CA, USA
    J Am Acad Child Adolesc Psychiatry 43:481-90. 2004
    ..To examine the neural basis of impairments in interpreting facial emotions in children and adolescents with autism spectrum disorders (ASD)...
  14. ncbi Specificity of brain activation patterns in people at genetic risk for Alzheimer disease
    Alison C Burggren
    Department of Psychiatry and Biobehavioral Sciences, Brain Mapping Division, UCLA School of Medicine, Los Angeles, CA 90095 7085, USA
    Am J Geriatr Psychiatry 10:44-51. 2002
    ....
  15. pmc fMRI activation in the amygdala and the orbitofrontal cortex in unmedicated subjects with major depressive disorder
    Jennifer D Townsend
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, and Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA
    Psychiatry Res 183:209-17. 2010
    ..The current study replicates previous research on unmedicated subjects showing no significant differences in amygdala function in depressed vs. control subjects with respect to simple tasks involving emotion observation...
  16. pmc fMRI abnormalities in dorsolateral prefrontal cortex during a working memory task in manic, euthymic and depressed bipolar subjects
    Jennifer Townsend
    Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA, USA
    Psychiatry Res 182:22-9. 2010
    ..The reduction of neural activation may suggest a trait-related deficit. Subjects with bipolar disorder activated other additional frontal and temporal regions, perhaps as a compensatory mechanism, but this remains to be further explored...
  17. ncbi Estrogen use and brain metabolic change in older adults. A preliminary report
    N L Rasgon
    Department of Psychiatry and Biobehavioral Sciences, University of California at Los Angeles, The Neuropsychiatric Institute, Los Angeles, CA 90095, USA
    Psychiatry Res 107:11-8. 2001
    ..These findings suggest that estrogen use may protect against regional cerebral metabolic decline in postmenopausal women...
  18. pmc Neural basis of self and other representation in autism: an FMRI study of self-face recognition
    Lucina Q Uddin
    Department of Psychiatry, Stanford University School of Medicine, Stanford, California, USA
    PLoS ONE 3:e3526. 2008
    ..Still, the neural mechanisms subserving self-representations in ASD are relatively unexplored...
  19. pmc Family history of Alzheimer's disease and hippocampal structure in healthy people
    Markus Donix
    Center for Cognitive Neurosciences, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at University of California Los Angeles, Semel Institute, Los Angeles, CA 90095, USA
    Am J Psychiatry 167:1399-406. 2010
    ..The authors investigated the influence of APOE-4 genotype and family history risks on cortical thickness in medial temporal lobe subregions among volunteers without cognitive impairment...
  20. pmc Effects of prenatal methamphetamine exposure on verbal memory revealed with functional magnetic resonance imaging
    Lisa H Lu
    Developmental Cognitive Neuroimaging Group, Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles, CA 90095 7334, USA
    J Dev Behav Pediatr 30:185-92. 2009
    ..We examined whether neurocognitive systems differed among children with differing prenatal teratogenic exposures when they engaged in a verbal memory task...
  21. pmc Reduced cortical thickness in hippocampal subregions among cognitively normal apolipoprotein E e4 carriers
    A C Burggren
    David Geffen School of Medicine at UCLA, Center for Cognitive Neurosciences, Semel Institute, 760 Westwood Plaza B8 169, Los Angeles, CA 90095, USA
    Neuroimage 41:1177-83. 2008
    ....
  22. pmc Reward processing in autism
    Ashley A Scott-Van Zeeland
    Center for Cognitive Neuroscience, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA
    Autism Res 3:53-67. 2010
    ..Together, these data support the hypothesis that children with ASD have diminished neural responses to SR, and that this deficit relates to social learning impairments...
  23. doi Selective corticostriatal dysfunction in schizophrenia: examination of motor and cognitive skill learning
    Karin Foerde
    Department of Psychology, University of California Los Angeles, Los Angeles, CA, USA
    Neuropsychology 22:100-9. 2008
    ..In contrast, patients were not impaired at learning on the SRT relative to controls, suggesting that patients with schizophrenia may have dysfunction in a specific corticostriatal subcircuit...
  24. doi Factors predicting language lateralization in patients with perisylvian vascular malformations. Clinical article
    Darrin J Lee
    Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California 90095 7039, USA
    J Neurosurg 113:723-30. 2010
    ..The authors conducted a study to determine the factors associated with right-sided language dominance in patients with cerebrovascular malformations...
  25. pmc Human hippocampal CA1 involvement during allocentric encoding of spatial information
    Nanthia A Suthana
    Center for Cognitive Neurosciences, Semel Institute, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, California 90095 1759, USA
    J Neurosci 29:10512-9. 2009
    ..Altogether, our results demonstrate that the CA1 subregion is involved in our ability to learn a map-like representation of an environment...
  26. pmc The neural correlates of religious and nonreligious belief
    Sam Harris
    UCLA Ahmanson Lovelace Brain Mapping Center, David Geffen School of Medicine, University of California Los Angeles UCLA, Los Angeles, California, United States of America
    PLoS ONE 4:e0007272. 2009
    ..Our lab previously has used functional neuroimaging to study belief as a general mode of cognition [1], and others have looked specifically at religious belief [2]. However, no research has compared these two states of mind directly...
  27. ncbi A dissociation of encoding and retrieval processes in the human hippocampus
    Laura L Eldridge
    Department of Psychology, University of California, Los Angeles, Los Angeles, California 90095, USA
    J Neurosci 25:3280-6. 2005
    ..Different components of the hippocampal circuit likely contribute to different degrees to the two basic memory functions...
  28. ncbi An implicit learning task activates medial temporal lobe in patients with Parkinson's disease
    Teena D Moody
    Department of Psychology, University of California, Los Angeles, Los Angeles, CA 90095 1563, USA
    Behav Neurosci 118:438-42. 2004
    ..Patients with PD also showed activation of the MTL during the weather-prediction task. These findings are consistent with an interaction between memory systems of the MTL and the striatum...
  29. ncbi Dissociating neural mechanisms of temporal sequencing and processing phonemes
    Jenna R Gelfand
    Brain Mapping Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Neuron 38:831-42. 2003
    ....
  30. ncbi Unfolding the human hippocampus with high resolution structural and functional MRI
    M M Zeineh
    UCLA School of Medicine, Los Angeles, CA, USA
    Anat Rec 265:111-20. 2001
    ..We explain the principles behind this method and illustrate its application to a novelty-encoding paradigm...
  31. ncbi Activation of language cortex with automatic speech tasks
    S Y Bookheimer
    Epilepsy Research Branch, NINDS, National Institutes of Health, Bethesda, MD, USA
    Neurology 55:1151-7. 2000
    ..To identify automatic speech tasks that reliably demonstrate increased regional cerebral blood flow (rCBF) in Broca's and Wernicke's areas of the cortex using PET...
  32. pmc Differentiating prenatal exposure to methamphetamine and alcohol versus alcohol and not methamphetamine using tensor-based brain morphometry and discriminant analysis
    Elizabeth R Sowell
    Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles, Los Angeles, California 90095, USA
    J Neurosci 30:3876-85. 2010
    ....
  33. pmc Neurodevelopmental changes in verbal working memory load-dependency: an fMRI investigation
    Elizabeth D O'Hare
    Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles 90095 7334, USA
    Neuroimage 42:1678-85. 2008
    ....
  34. ncbi Working memory effects on semantic processing: priming differences in pars orbitalis
    Fred W Sabb
    Semel Institute for Neuroscience and Human Behavior, Department of Psychiatry, University of California, Los Angeles 760 Westwood Plaza, Los Angeles, CA 90095, USA
    Neuroimage 37:311-22. 2007
    ..fMRI signal changes in dorsolateral prefrontal cortex were negatively correlated with signal changes in pars orbitalis. The findings suggest that controlled semantic processing and working memory share neural system resources...
  35. pmc Cognitive and cerebral metabolic effects of celecoxib versus placebo in people with age-related memory loss: randomized controlled study
    Gary W Small
    Department of Psychiatry and Biobehavioral Sciences and Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at the University of California, Los Angeles, CA 90024, USA
    Am J Geriatr Psychiatry 16:999-1009. 2008
    ....
  36. pmc Influence of cognitive status, age, and APOE-4 genetic risk on brain FDDNP positron-emission tomography imaging in persons without dementia
    Gary W Small
    Semel Institute, 760 Westwood Plaza, Ste 88 201, Los Angeles, CA 90024, USA
    Arch Gen Psychiatry 66:81-7. 2009
    ..Here we investigated whether known risk factors for Alzheimer disease and dementia are associated with FDDNP-PET binding...
  37. doi Your brain on Google: patterns of cerebral activation during internet searching
    Gary W Small
    Department of Psychiatry and Biobehavioral Sciences and Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA
    Am J Geriatr Psychiatry 17:116-26. 2009
    ....
  38. ncbi An event-related fMRI study of artificial grammar learning in a balanced chunk strength design
    Matthew D Lieberman
    University of California, Los Angeles, CA 90095 1563, USA
    J Cogn Neurosci 16:427-38. 2004
    ..Additionally, functional connectivity analyses revealed caudate and medial temporal lobe activations to be strongly negatively correlated (r= -.88) with one another during the performance of this task...
  39. doi Abnormal brain activation during working memory in children with prenatal exposure to drugs of abuse: the effects of methamphetamine, alcohol, and polydrug exposure
    Florence F Roussotte
    Department of Neurology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA 90095 7332, USA
    Neuroimage 54:3067-75. 2011
    ....
  40. pmc Alterations in functional activation in euthymic bipolar disorder and schizophrenia during a working memory task
    Liberty S Hamilton
    Laboratory of Neuro Imaging, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095 7334, USA
    Hum Brain Mapp 30:3958-69. 2009
    ..Both patient groups showed some regional task-related hypoactivation compared to controls across the brain. Within DLPFC specifically, patients with schizophrenia exhibited more severe WM-related dysfunction than bipolar subjects...
  41. pmc No neural evidence of statistical learning during exposure to artificial languages in children with autism spectrum disorders
    Ashley A Scott-Van Zeeland
    Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA
    Biol Psychiatry 68:345-51. 2010
    ..Importantly, early word segmentation skills have been shown to predict later language development in typically developing (TD) children...
  42. pmc Entorhinal cortex structure and functional MRI response during an associative verbal memory task
    MEREDITH N BRASKIE
    Ahmanson Lovelace Brain Mapping Center, David Geffen School of Medicine, University of California, Los Angeles, California, USA
    Hum Brain Mapp 30:3981-92. 2009
    ..Our results suggest that in healthy older adults, processes that engage frontal regions during memory retrieval are related to ERC structure...
  43. ncbi Dynamics of the hippocampus during encoding and retrieval of face-name pairs
    Michael M Zeineh
    Ahmanson Lovelace Brain Mapping Center, UCLA School of Medicine, 660 Charles Young Drive South, Los Angeles, CA 90095 7085, USA
    Science 299:577-80. 2003
    ..Activity in the subiculum showed the same temporal decline, but primarily during retrieval. Our results demonstrate that subdivisions within the hippocampus make distinct contributions to new memory formation...
  44. ncbi Hippocampal atrophy in persons with age-associated memory impairment: volumetry within a common space
    Michael S Mega
    Department of Neurology and Laboratory of Neuro Imaging, UCLA School of Medicine, Los Angeles, California 90095 1769, USA
    Psychosom Med 64:487-92. 2002
    ..The objective of this study is to demonstrate the assessment of hippocampal atrophy within a standard brain atlas for persons with age-associated memory impairment (AAMI) compared with cognitively intact elderly...
  45. doi The reliability of neuroanatomy as a predictor of eloquence: a review
    Nader Pouratian
    Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 7049, USA
    Neurosurg Focus 28:E3. 2010
    ..Perhaps most importantly, an individualized approach to mapping patients with brain tumors ensures that the risk of iatrogenic functional injury is minimized while maximizing the extent of resection...
  46. pmc Differential FDDNP PET patterns in nondemented middle-aged and older adults
    Linda M Ercoli
    Department of Psychiatry and Biobehavioral Sciences and Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90095 9668, USA
    Am J Geriatr Psychiatry 17:397-406. 2009
    ....
  47. pmc Depression and anxiety symptoms are associated with cerebral FDDNP-PET binding in middle-aged and older nondemented adults
    Helen Lavretsky
    Department of Psychiatry and Biobehavioral Sciences and Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90095 9668, USA
    Am J Geriatr Psychiatry 17:493-502. 2009
    ....
  48. ncbi Blunted activation in orbitofrontal cortex during mania: a functional magnetic resonance imaging study
    Lori L Altshuler
    Department of Psychiatry, Los Angeles, California, USA
    Biol Psychiatry 58:763-9. 2005
    ..Specifically, we sought to evaluate activation in the lateral orbitofrontal cortex, a brain region that is normally activated during activities that require response inhibition...
  49. ncbi Aging and brain activation with working memory tasks: an fMRI study of connectivity
    Ian A Cook
    UCLA Semel Institute for Neuroscience and Human Behavior, California 90024 1759, USA
    Int J Geriatr Psychiatry 22:332-42. 2007
    ..We hypothesized healthy older subjects would show lower connectivity than younger subjects...
  50. ncbi Functional magnetic resonance imaging of verbal learning in children with heavy prenatal alcohol exposure
    Elizabeth R Sowell
    Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles, California 90095 7334, USA
    Neuroreport 18:635-9. 2007
    ....
  51. ncbi Effects of a 14-day healthy longevity lifestyle program on cognition and brain function
    Gary W Small
    Department of Psychiatry and Biobehavioral Sciences and Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA 90024, USA
    Am J Geriatr Psychiatry 14:538-45. 2006
    ..The objective of this study was to determine the effects of a 14-day healthy longevity lifestyle program on cognition and cerebral metabolism in people with mild age-related memory complaints...
  52. ncbi Perceived loss of memory ability and cerebral metabolic decline in persons with the apolipoprotein E-IV genetic risk for Alzheimer disease
    Linda Ercoli
    Department of Psychiatry, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, 90024, USA
    Arch Gen Psychiatry 63:442-8. 2006
    ..Concerns about age-related memory loss are greater in persons who have the apolipoprotein E-IV (APOE4) genetic risk for Alzheimer disease, but the correlation between the degree of concerns and future cerebral metabolic decline is unknown...
  53. pmc Understanding emotions in others: mirror neuron dysfunction in children with autism spectrum disorders
    Mirella Dapretto
    Ahmanson Lovelace Brain Mapping Center, Semel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, 90095, USA
    Nat Neurosci 9:28-30. 2006
    ..Notably, activity in this area was inversely related to symptom severity in the social domain, suggesting that a dysfunctional 'mirror neuron system' may underlie the social deficits observed in autism...
  54. ncbi PET of brain amyloid and tau in mild cognitive impairment
    Gary W Small
    Department of Psychiatry and Biobehavioral Sciences and the Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at the University of California, Los Angeles, USA
    N Engl J Med 355:2652-63. 2006
    ..Noninvasive methods to detect these abnormal proteins are potentially useful in developing surrogate markers for drug discovery and diagnostics...
  55. ncbi An fMRI investigation of race-related amygdala activity in African-American and Caucasian-American individuals
    Matthew D Lieberman
    Department of Psychology, Franz Hall, University of California Los Angeles, Los Angeles, California 90095 1563, USA
    Nat Neurosci 8:720-2. 2005
    ..Additionally, verbal encoding of African-American targets produced significantly less amygdala activity than perceptual encoding of African-American targets...
  56. pmc Evidence for deficient modulation of amygdala response by prefrontal cortex in bipolar mania
    Lara C Foland
    Laboratory of Neuroimaging, Department of Neurology, University of California, Los Angeles, CA, USA
    Psychiatry Res 162:27-37. 2008
    ..These findings, taken in context with previous fMRI studies of bipolar mania, suggest that reductions in inhibitory frontal activity in these patients may lead to an increased reactivity of the amygdala...
  57. pmc Current and future uses of neuroimaging for cognitively impaired patients
    Gary W Small
    Department of Psychiatry and Biobehavioral Sciences and Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA
    Lancet Neurol 7:161-72. 2008
    ....
  58. ncbi The neural correlates of motor skill automaticity
    Russell A Poldrack
    Department of Psychology, University of California, Los Angeles, Los Angeles, California 90095 1563, USA
    J Neurosci 25:5356-64. 2005
    ....
  59. pmc Mapping white matter integrity and neurobehavioral correlates in children with fetal alcohol spectrum disorders
    Elizabeth R Sowell
    Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles, Los Angeles, California 90095 7334, USA
    J Neurosci 28:1313-9. 2008
    ..This suggests that this region of white matter is particularly susceptible to damage from prenatal alcohol exposure and that disruption of splenial fibers in this group is associated with poorer visuomotor integration...
  60. ncbi Memory self-appraisal and depressive symptoms in people at genetic risk for Alzheimer's disease
    G W Small
    Department of Psychiatry and Biobehavioral Sciences, The Neuropsychiatric Institute, University of California at Los Angeles, 90024, USA
    Int J Geriatr Psychiatry 16:1071-7. 2001
    ..No previous study has focused on subjective memory complaints and depressive symptoms in the same subject population at genetic risk for Alzheimer's disease...
  61. ncbi Form and content: dissociating syntax and semantics in sentence comprehension
    M Dapretto
    Ahmanson Lovelace Brain Mapping Center, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles 90095, USA
    Neuron 24:427-32. 1999
    ....
  62. pmc A unique adolescent response to reward prediction errors
    Jessica R Cohen
    Department of Psychology, University of California Los Angeles, Los Angeles, California, USA
    Nat Neurosci 13:669-71. 2010
    ..This suggests that heightened dopaminergic prediction error responsivity contributes to adolescent reward seeking...
  63. pmc Vascular health risks and fMRI activation during a memory task in older adults
    MEREDITH N BRASKIE
    Ahmanson Lovelace Brain Mapping Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Neurobiol Aging 31:1532-42. 2010
    ..Our results are similar to those in prior AD risk research, and suggest that fMRI reveals an abnormal response to cognitive processes in cognitively intact older adults with increased vascular risk...
  64. pmc Relationships between brain activation and brain structure in normally developing children
    Lisa H Lu
    UCLA Laboratory of Neuro Imaging, Department of Neurology, Los Angeles, CA 90095, USA
    Cereb Cortex 19:2595-604. 2009
    ..These results localized cortical regions where mature morphology corresponds to mature patterns of activation, and may suggest a role for experience in mediating brain structure-activation relationships...
  65. pmc Advances in high-resolution imaging and computational unfolding of the human hippocampus
    Arne D Ekstrom
    Center for Cognitive Neuroscience, Semel Institute, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095 7039, USA
    Neuroimage 47:42-9. 2009
    ..Together, these methods provide a means to improve imaging of neural activity in the human hippocampus and surrounding cortex during cognitive tasks...
  66. ncbi Functional MRI changes during panic anticipation and imagery exposure
    A Bystritsky
    Department of Psychiatry, UCLA/NPI, 300 UCLA Medical Plaza, 2335 Los Angeles, CA 90095, USA
    Neuroreport 12:3953-7. 2001
    ..We propose that this pattern of activity may enhance the encoding and retrieval of strong emotional events, facilitating the recapitulation of traumatic experiences and leading to panic disorder in vulnerable individuals...
  67. doi Regional hippocampal atrophy in multiple sclerosis
    N L Sicotte
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Brain 131:1134-41. 2008
    ..Further understanding of this process could provide targets for therapeutic interventions including neuroprotective treatments...
  68. ncbi Temporal spatial differences observed by functional MRI and human intraoperative optical imaging
    A F Cannestra
    Laboratory of Neuro Imaging, Division of Neurosurgery, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095-1769, USA
    Cereb Cortex 11:773-82. 2001
    ..The temporal/spatial co-localization of the iOIS signal and the fMRI initial dip suggests the initial fMRI dip and the iOIS signal may result from similar physiologic events...
  69. pmc Spatial and temporal episodic memory retrieval recruit dissociable functional networks in the human brain
    Arne D Ekstrom
    Center for Cognitive Neurosciences, Semel Institute, Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, California 90095, USA
    Learn Mem 14:645-54. 2007
    ....
  70. ncbi Utility of preoperative functional magnetic resonance imaging for identifying language cortices in patients with vascular malformations
    Nader Pouratian
    Department of Neurology, Laboratory of Neuro Imaging, UCLA School of Medicine, University of California, Los Angeles, California, USA
    Neurosurg Focus 13:e4. 2002
    ....
  71. ncbi Utility of preoperative functional magnetic resonance imaging for identifying language cortices in patients with vascular malformations
    Nader Pouratian
    Department of Neurology, UCLA School of Medicine, University of California, Los Angeles, USA
    J Neurosurg 97:21-32. 2002
    ....
  72. ncbi Applications and limitations of perfusion-dependent functional brain mapping for neurosurgical guidance
    Nader Pouratian
    Department of Surgery, Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California at Los Angeles, California 90095 1769, USA
    Neurosurg Focus 15:E2. 2003
    ..The authors review the evolution, interpretation, and limitations of perfusion-based brain mapping techniques, with special attention to clinical implications of the brain maps...
  73. ncbi Structural and functional neuroimaging in Alzheimer's disease: an update
    Alison C Burggren
    UCLA Department of Psychiatry and Biobehavioral Sciences, Brain Mapping Division, Ahmanson Lovelace Brain Mapping Center, 660 Charles E Young Dr South rm 205, Los Angeles, CA 90095 7085, USA
    Curr Top Med Chem 2:385-93. 2002
    ..A methodology review will be included here as well as a critical evaluation of the advantages and disadvantages of the various techniques...
  74. ncbi Recruitment of anterior dorsolateral prefrontal cortex in human reasoning: a parametric study of relational complexity
    James K Kroger
    Department of Psychology, University of Michigan, Ann Arbor, MI 48109 1109, USA
    Cereb Cortex 12:477-85. 2002
    ..Our data provide evidence that brain regions specific to integrating complex relations among stimuli are distinct from those involved in coping with general task difficulty and with working-memory demands...
  75. pmc Offering to share: how to put heads together in autism neuroimaging
    Matthew K Belmonte
    Department of Human Development, Cornell University, Martha Van Rensselaer Hall, Ithaca, NY 14853 4401, USA
    J Autism Dev Disord 38:2-13. 2008
    ..A theme in these requirements is the need to preserve creative approaches and risk-taking within individual laboratories at the same time as common standards are provided for these laboratories to build on...
  76. ncbi Functional magnetic resonance imaging and optical imaging for dominant-hemisphere perisylvian arteriovenous malformations
    Andrew F Cannestra
    Laboratory of Neuro Imaging, Department of Neurology, and Division of Neurosurgery, University of California at Los Angeles School of Medicine, 90095 1769, USA
    Neurosurgery 55:804-12; discussion 812-4. 2004
    ..We stratified the patients into three categories based on preoperative functional magnetic resonance imaging (fMRI) language activation pattern and relative location of the AVM...
  77. ncbi Category-specific naming deficit identified by intraoperative stimulation mapping and postoperative neuropsychological testing. Case report
    Nader Pouratian
    Laboratory of Neuro Imaging, Department of Neurology, University of California at Los Angeles School of Medicine, California 90095 1769, USA
    J Neurosurg 99:170-6. 2003
    ..They also emphasize the roles of preoperative and intraoperative testing in predicting clinical outcomes...
  78. ncbi Variability of intraoperative electrocortical stimulation mapping parameters across and within individuals
    Nader Pouratian
    Laboratory of Neuro Imaging and Brain Mapping Center, Department of Neurology, USA
    J Neurosurg 101:458-66. 2004
    ..The authors retrospectively reviewed their eperience with intraoperative electrocortical stimulation mapping to characterize variability of both mapping and afterdischarge thresholds...
  79. ncbi The neural correlates of grammatical gender decisions in Spanish
    Arturo E Hernandez
    Department of Psychology, University of Houston, 126 Heyne Building, Houston, TX 77204 5022, USA
    Neuroreport 15:863-6. 2004
    ..Taken together they support the notion that gender decisions for opaque items requires deeper and more effortful processing during the retrieval of lexical and syntactic information...

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