James A Bonner

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. doi request reprint Treatment of small cell lung cancer with TRA-8 in combination with cisplatin and radiation
    James A Bonner
    Department of Radiation Oncology, The University of Alabama, Birmingham, AL 35249, USA
    Radiother Oncol 101:183-9. 2011
  2. ncbi request reprint Anti-EGFR-mediated radiosensitization as a result of augmented EGFR expression
    James A Bonner
    Department of Radiation Oncology, The University of Alabama School of Medicine, Birmingham, 35294 3300, USA
    Int J Radiat Oncol Biol Phys 59:2-10. 2004
  3. doi request reprint Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
    James A Bonner
    University of Alabama, Birmingham, AL, USA
    Lancet Oncol 11:21-8. 2010
  4. doi request reprint Inhibition of STAT-3 results in greater cetuximab sensitivity in head and neck squamous cell carcinoma
    James A Bonner
    Department of Radiation Oncology, The University of Alabama at Birmingham, USA
    Radiother Oncol 99:339-43. 2011
  5. ncbi request reprint Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells
    James A Bonner
    Department of Radiation Oncology, University of Alabama School of Medicine, Birmingham, Alabama, USA
    Int J Radiat Oncol Biol Phys 58:950-8. 2004
  6. doi request reprint Dosimetric factors associated with long-term dysphagia after definitive radiotherapy for squamous cell carcinoma of the head and neck
    Jimmy J Caudell
    Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Int J Radiat Oncol Biol Phys 76:403-9. 2010
  7. pmc Patterns of prophylactic gastrostomy tube placement in head and neck cancer patients: a consideration of the significance of social support and practice variation
    Julie L Locher
    Department of Medicine, Division of Gerontology, Geriatrics, and Palliative Care, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Laryngoscope 123:1918-25. 2013
  8. doi request reprint Gastrostomy tube placement and use in patients with head and neck cancer
    Julie L Locher
    Department of Medicine, Division of Gerontology, Geriatrics, and Palliative Care, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Head Neck 34:422-8. 2012
  9. doi request reprint Adjuvant radiotherapy for pancreatic cancer is associated with a survival benefit primarily in stage IIB patients
    John S Moody
    Department of Radiation Oncology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294 3300, USA
    J Gastroenterol 44:84-91. 2009
  10. pmc Synthesis and preliminary biological evaluation of high-drug-load paclitaxel-antibody conjugates for tumor-targeted chemotherapy
    Sherly Quiles
    Department of Radiation Oncology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Med Chem 53:586-94. 2010

Collaborators

Detail Information

Publications60

  1. doi request reprint Treatment of small cell lung cancer with TRA-8 in combination with cisplatin and radiation
    James A Bonner
    Department of Radiation Oncology, The University of Alabama, Birmingham, AL 35249, USA
    Radiother Oncol 101:183-9. 2011
    ..This study focused on the interaction of cisplatin/radiation with the anti-human DR5 monoclonal antibody TRA-8 in SCLC cells. TRA-8 binds specifically to DR5 and has been shown to activate apoptosis...
  2. ncbi request reprint Anti-EGFR-mediated radiosensitization as a result of augmented EGFR expression
    James A Bonner
    Department of Radiation Oncology, The University of Alabama School of Medicine, Birmingham, 35294 3300, USA
    Int J Radiat Oncol Biol Phys 59:2-10. 2004
    ..To explore this question, cells (LS174T) that did not display inherent anti-EGFR treatment-induced radiosensitization were selected for studies that could potentially enhance EGFR expression...
  3. doi request reprint Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
    James A Bonner
    University of Alabama, Birmingham, AL, USA
    Lancet Oncol 11:21-8. 2010
    ..Here we report the 5-year survival data, and investigate the relation between cetuximab-induced rash and survival...
  4. doi request reprint Inhibition of STAT-3 results in greater cetuximab sensitivity in head and neck squamous cell carcinoma
    James A Bonner
    Department of Radiation Oncology, The University of Alabama at Birmingham, USA
    Radiother Oncol 99:339-43. 2011
    ....
  5. ncbi request reprint Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells
    James A Bonner
    Department of Radiation Oncology, University of Alabama School of Medicine, Birmingham, Alabama, USA
    Int J Radiat Oncol Biol Phys 58:950-8. 2004
    ....
  6. doi request reprint Dosimetric factors associated with long-term dysphagia after definitive radiotherapy for squamous cell carcinoma of the head and neck
    Jimmy J Caudell
    Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Int J Radiat Oncol Biol Phys 76:403-9. 2010
    ..Intensification of radiotherapy and chemotherapy for head-and-neck cancer may lead to increased rates of dysphagia. Dosimetric predictors of objective findings of long-term dysphagia were sought...
  7. pmc Patterns of prophylactic gastrostomy tube placement in head and neck cancer patients: a consideration of the significance of social support and practice variation
    Julie L Locher
    Department of Medicine, Division of Gerontology, Geriatrics, and Palliative Care, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Laryngoscope 123:1918-25. 2013
    ....
  8. doi request reprint Gastrostomy tube placement and use in patients with head and neck cancer
    Julie L Locher
    Department of Medicine, Division of Gerontology, Geriatrics, and Palliative Care, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Head Neck 34:422-8. 2012
    ..This study describes the frequency and timing of gastrostomy tube placement and corresponding Medicare nutritional support claims in patients with head and neck cancer...
  9. doi request reprint Adjuvant radiotherapy for pancreatic cancer is associated with a survival benefit primarily in stage IIB patients
    John S Moody
    Department of Radiation Oncology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294 3300, USA
    J Gastroenterol 44:84-91. 2009
    ..This study examines the survival impact of postoperative RT in a large population-based database...
  10. pmc Synthesis and preliminary biological evaluation of high-drug-load paclitaxel-antibody conjugates for tumor-targeted chemotherapy
    Sherly Quiles
    Department of Radiation Oncology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Med Chem 53:586-94. 2010
    ..These conjugates may have potential in the development of high-drug-load tumor-targeting taxanes...
  11. ncbi request reprint Results of a phase II study of high-dose thoracic radiation therapy with concurrent cisplatin and etoposide in limited-stage small-cell lung cancer (NCCTG 95-20-53)
    Steven E Schild
    Mayo Clinic Arizona, Department of Radiation Oncology, Scottsdale, AZ 85259, USA
    J Clin Oncol 25:3124-9. 2007
    ..To evaluate the outcome of patients with limited-stage small-cell lung cancer (L-SCLC) treated with cisplatin and etoposide (PE), early prophylactic cranial irradiation (PCI), and high-dose twice-daily thoracic radiotherapy (bid RT)...
  12. ncbi request reprint Site-specifically traced drug release and biodistribution of a paclitaxel-antibody conjugate toward improvement of the linker structure
    Ahmad Safavy
    Department of Radiation Oncology and Medicine, Biostatistics and Bioinformatics Unit, and Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Bioconjug Chem 15:1264-74. 2004
    ..These results demonstrated the first time use of radioiodinated 3'-OH-PTX for in vivo tracing of a paclitaxel conjugate and application of the resulting information to the design of a therapeutically more useful PTX-MAb linker...
  13. ncbi request reprint Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
    James A Bonner
    Department of Medicine, University of Alabama, Birmingham, USA
    N Engl J Med 354:567-78. 2006
    ....
  14. doi request reprint Impact of average weekly dose of radiation during radiotherapy alone or chemoradiotherapy in head and neck cancer
    Aleksandar F Dragovic
    Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Head Neck 33:1551-6. 2011
    ..We investigated patient outcomes using a new parameter: the average weekly dose (AWD)...
  15. doi request reprint Factors associated with long-term dysphagia after definitive radiotherapy for locally advanced head-and-neck cancer
    Jimmy J Caudell
    Department of Radiation Oncology, University of Alabama Birmingham, Birmingham, AL, USA
    Int J Radiat Oncol Biol Phys 73:410-5. 2009
    ..The use of altered fractionation radiotherapy (RT) regimens, as well as concomitant chemotherapy and RT, to intensify therapy for locally advanced head-and-neck cancer can lead to increased rates of long-term dysphagia...
  16. ncbi request reprint Synthesis and biological evaluation of paclitaxel-C225 conjugate as a model for targeted drug delivery
    Ahmad Safavy
    Department of Radiation Oncology, Biostatistics Unit, University of Alabama at Birmingham, 35294, USA
    Bioconjug Chem 14:302-10. 2003
    ....
  17. doi request reprint Dosimetric analysis of imaging changes following pulmonary stereotactic body radiation therapy
    Brendan M Prendergast
    Department of Radiation Oncology Thoracic Surgery, University of Alabama, Birmingham, Alabama, USA
    J Med Imaging Radiat Oncol 55:90-6. 2011
    ..The aim of this study was to determine whether late patterns of pulmonary fibrosis are related to specific radiation doses administered during thoracic stereotactic body radiation therapy (SBRT)...
  18. pmc Kinomic profiling approach identifies Trk as a novel radiation modulator
    John S Jarboe
    Department of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, AL 35249 6832, USA
    Radiother Oncol 103:380-7. 2012
    ..Ionizing radiation treatment is used in over half of all cancer patients, thus determining the mechanisms of response or resistance is critical for the development of novel treatment approaches...
  19. doi request reprint Small-cell lung cancer: prognostic factors and changing treatment over 15 years
    Laurie E Gaspar
    University of Colorado School of Medicine, Department of Radiation Oncology, 1665 Aurora Court, Suite 1032, MS F706, Aurora, CO 80045 0510, USA
    Clin Lung Cancer 13:115-22. 2012
    ..Sixty-eight thousand six hundred eleven patients with SCLC in the National Cancer Data Base (NCDB) were analyzed to describe demographic, treatment, and survival changes between 1992 and 2007...
  20. doi request reprint Flattening filter-free linac improves treatment delivery efficiency in stereotactic body radiation therapy
    Brendan M Prendergast
    Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    J Appl Clin Med Phys 14:4126. 2013
    ..In addition, treatment with a FFF linac is associated with less physician-ordered image guidance, which contributes to further improvement in treatment delivery efficiency...
  21. pmc HER2 overexpression renders human breast cancers sensitive to PARP inhibition independently of any defect in homologous recombination DNA repair
    Somaira Nowsheen
    Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA
    Cancer Res 72:4796-806. 2012
    ..Our findings indicate that PARP inhibitors may be a novel therapeutic strategy for sporadic HER2+ breast cancer patients...
  22. pmc The poly(ADP-Ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy
    Somaira Nowsheen
    Department of Radiation Oncology, University of Alabama at Birmingham School of Medicine, USA
    Radiother Oncol 99:331-8. 2011
    ..Thus, we studied whether inhibition of poly(ADP-Ribose) polymerase (PARP), a key DNA repair enzyme, could improve efficacy of radiotherapy in human head and neck cancer...
  23. ncbi request reprint Treatment of pancreatic cancer xenografts with Erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation
    Donald J Buchsbaum
    Department of Radiation Oncology, University of Alabama at Birmingham, Wallace Tumor Institute, Room 674, 1824 6th Avenue South, Birmingham, AL 35294, USA
    Int J Radiat Oncol Biol Phys 54:1180-93. 2002
    ..To investigate treatment of human pancreatic cancer cell lines and xenografts with combinations of Erbitux (IMC-C225) anti-epidermal growth factor receptor (EGFR) antibody, gemcitabine, and radiation...
  24. doi request reprint Comparison of methods to reduce dose to swallowing-related structures in head and neck cancer
    Jimmy J Caudell
    Department of Radiation Oncology, University of Alabama at Birmingham, USA
    Int J Radiat Oncol Biol Phys 77:462-7. 2010
    ..Organ avoidance becomes difficult when the primary tumor or involved nodes are present at the level of the larynx...
  25. ncbi request reprint Inhibition of STAT-3 results in radiosensitization of human squamous cell carcinoma
    James A Bonner
    Department of Radiation Oncology, The University of Alabama at Birmingham, AL 35233, USA
    Radiother Oncol 92:339-44. 2009
    ..Studies were performed to determine if inhibition of this downstream protein produces radiosensitization...
  26. ncbi request reprint Radiosensitization by antisense anti-MDM2 mixed-backbone oligonucleotide in in vitro and in vivo human cancer models
    Zhuo Zhang
    Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0019, USA
    Clin Cancer Res 10:1263-73. 2004
    ..In the present study, we investigated the effect of the antisense oligonucleotide on radiation therapy...
  27. ncbi request reprint Differential responses by pancreatic carcinoma cell lines to prolonged exposure to Erbitux (IMC-C225) anti-EGFR antibody
    Zhi Qiang Huang
    Division of General Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294 0016, USA
    J Surg Res 111:274-83. 2003
    ..We investigated the effect of prolonged Erbitux treatment to the sensitivity to gemcitabine and/or radiation and the epidermal growth factor receptor (EGFR) signal transduction pathway...
  28. pmc Prognostic significance of thyroid or cricoid cartilage invasion in laryngeal or hypopharyngeal cancer treated with organ preserving strategies
    Marcus M Wagner
    Department of Radiation Oncology, University of Alabama at Birmingham, Hazelrig Salter Radiation Oncology Center, 1700 6th Avenue South, Birmingham, AL 35249 6832, USA
    Radiat Oncol 7:219. 2012
    ..A retrospective review of our experience was performed...
  29. doi request reprint Examination of laryngoesophageal dysfunction-free survival as an endpoint in nonsurgical treatment of squamous cell carcinomas of the larynx and hypopharynx
    Jimmy J Caudell
    Department of Radiation Oncology, University of Mississippi Medical Center, Jackson, Mississippi, USA
    Cancer 117:4447-51. 2011
    ..The authors of this report examined LEDFS in the context of definitive radiotherapy alone (RT) or with concurrent chemoradiotherapy (CRT)...
  30. doi request reprint Margin on gross tumor volume and risk of local recurrence in head-and-neck cancer
    Jimmy J Caudell
    Department of Radiation Oncology, University of Alabama Birmingham, Birmingham, AL 35249, USA
    Int J Radiat Oncol Biol Phys 76:164-8. 2010
    ....
  31. ncbi request reprint Validation of target volume and position in respiratory gated CT planning and treatment
    Sui Shen
    Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Med Phys 30:3196-205. 2003
    ..5-2.5 mm safety margin can be added regardless of the size of residual motion error. For respiratory rates > or = 30 cycles/min, the effectiveness of gating is limited by large residual motion in the 1 s CT acquisition time...
  32. ncbi request reprint Design and development of water-soluble curcumin conjugates as potential anticancer agents
    Ahmad Safavy
    Department of Radiation Oncology, University of Alabama at Birmingham, 1824 6th Avenue S, Birmingham, AL 35294 6832, USA
    J Med Chem 50:6284-8. 2007
    ..Synthesis, analyses of the rate of drug release, and cytotoxicity studies are herein reported. The water-soluble conjugates may provide information useful for the development of injectable curcumin conjugates...
  33. pmc Dosimetric impact of target definitions on normal structures in head and neck cancer
    Micah T Monaghan
    Department of Radiation Oncology, The University of Alabama at Birmingham, 1700 Sixth Avenue South, Birmingham, AL 35249, USA
    Head Neck Oncol 3:34. 2011
    ..Previous work by our group suggests smaller target volumes may result in equivalent locoregional control for head and neck cancer. We evaluated whether smaller target volumes may also result in improved normal tissue sparing...
  34. pmc Phase III comparison of prophylactic cranial irradiation versus observation in patients with locally advanced non-small-cell lung cancer: primary analysis of radiation therapy oncology group study RTOG 0214
    Elizabeth M Gore
    Department of Radiation Oncology, Medical College of Wisconsin, 9200 W Wisconsin Ave, Milwaukee, WI 53213, USA
    J Clin Oncol 29:272-8. 2011
    ..This study was conducted to determine if prophylactic cranial irradiation (PCI) improves survival in locally advanced non-small-cell lung cancer (LA-NSCLC)...
  35. ncbi request reprint RapidArc radiation therapy: first year experience at the University of Alabama at Birmingham
    Richard A Popple
    Department of Radiation Oncology, The University of Alabama at Birmingham, Birmingham, Alabama, USA
    Int J Radiat Oncol Biol Phys 77:932-41. 2010
    ..To evaluate treatment planning and delivery for patients treated during our initial year of experience with RapidArc radiation therapy...
  36. pmc Cetuximab augments cytotoxicity with poly (adp-ribose) polymerase inhibition in head and neck cancer
    Somaira Nowsheen
    Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America
    PLoS ONE 6:e24148. 2011
    ..Furthermore, this strategy may also be feasible for other EGFR overexpressing tumors, including lung and brain cancers...
  37. ncbi request reprint Locoregional failure and the risk of distant metastasis after modern radiotherapy for head and neck cancer
    Aleksandar F Dragovic
    Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Head Neck 35:381-7. 2013
    ..Evolving epidemiology and improvements in locoregional therapy necessitate reassessment of the relationship between locoregional failure and distant metastasis in squamous cell carcinoma of the head and neck (SCCHN)...
  38. pmc MARCKS regulates growth and radiation sensitivity and is a novel prognostic factor for glioma
    John S Jarboe
    The Departments of Radiation Oncology, The University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Clin Cancer Res 18:3030-41. 2012
    ..This study assessed whether myristoylated alanine-rich C-kinase substrate (MARCKS) can regulate glioblastoma multiforme (GBM) growth, radiation sensitivity, and clinical outcome...
  39. doi request reprint Locoregionally advanced head and neck cancer treated with primary radiotherapy: a comparison of the addition of cetuximab or chemotherapy and the impact of protocol treatment
    Jimmy J Caudell
    Department of Radiation Oncology, University of Alabama Birmingham, Birmingham, AL 35249, USA
    Int J Radiat Oncol Biol Phys 71:676-81. 2008
    ..However the optimal treatment regimen has not been defined. A retrospective study was performed to compare outcomes in patients who were treated definitively with ExRT or ChRT...
  40. doi request reprint Prophylactic percutaneous endoscopic gastrostomy tube placement in treatment of head and neck cancer: a comprehensive review and call for evidence-based medicine
    Julie L Locher
    Department of Medicine, Division of Gerontology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    JPEN J Parenter Enteral Nutr 35:365-74. 2011
    ..PEG tube placement, however, is not without risks...
  41. ncbi request reprint Epidermal growth factor receptor as a therapeutic target in head and neck cancer
    James A Bonner
    University of Alabama at Birmingham, 35294 3300, USA
    Semin Radiat Oncol 12:11-20. 2002
    ....
  42. ncbi request reprint Results of combined-modality therapy for limited-stage small cell lung carcinoma in the elderly
    Steven E Schild
    Department of Radiation Oncology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA
    Cancer 103:2349-54. 2005
    ..No difference in survival was identified between the two arms. The current analysis examined the relation between age and outcome for patients treated during this trial...
  43. doi request reprint Stage-specific survival differences associated with postoperative radiotherapy for gastrointestinal cancers
    John S Moody
    Department of Radiation Oncology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA
    J Gastrointest Cancer 39:86-99. 2008
    ..To study the frequency and effect associated with postoperative radiotherapy (RT) for patients with resected gastrointestinal (GI) cancers...
  44. ncbi request reprint Limited-stage small-cell lung cancer (stages I-III): observations from the National Cancer Data Base
    Laurie E Gaspar
    Department of Radiation Oncology, University of Colorado at Denver and Health Sciences Center, Aurora, CO 80045 0510, USA
    Clin Lung Cancer 6:355-60. 2005
    ..These results demonstrate the continued need for the evaluation of new treatments in this group of patients...
  45. doi request reprint Diagnosis-to-treatment interval and control of locoregionally advanced head and neck cancer
    Jimmy J Caudell
    Department of Radiation Oncology, University of Mississippi Medical Center, 350 Woodrow Wilson Dr, Ste 1600, Jackson, MS 39213, USA
    Arch Otolaryngol Head Neck Surg 137:282-5. 2011
    ..To assess the impact of prolonged diagnosis-to-treatment interval (DTI) that falls in the time frame associated with the increasing complexity of planning treatment for patients with locoregionally advanced head and neck cancer (LAHNC)...
  46. pmc Emerging roles of glycogen synthase kinase 3 in the treatment of brain tumors
    Caroline N Mills
    Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama Birmingham School of Medicine Birmingham, AL, USA
    Front Mol Neurosci 4:47. 2011
    ..A thorough understanding of this versatile protein is critical for improving the outcome of various diseases, especially cancer...
  47. ncbi request reprint Model prediction of treatment planning for dose-fractionated radioimmunotherapy
    Sui Shen
    Department of Radiation Oncology, University of Alabama at Birmingham, 35294, USA
    Cancer 94:1264-9. 2002
    ..Clinical trials of radioimmunotherapy (RIT) often use dose fractionation to reduce marrow toxicity. The dosing scheme can be optimized if marrow and tumor cell kinetics following radiation exposure are known...
  48. ncbi request reprint Quality of life in head and neck cancer patients after treatment with high-dose radiotherapy alone or in combination with cetuximab
    Desmond Curran
    Omega Research, Dublin, Ireland
    J Clin Oncol 25:2191-7. 2007
    ..In this randomized, phase III study, quality of life (QoL) was assessed in patients with locoregionally advanced squamous cell carcinoma of the head and neck (SCCHN) after high-dose radiotherapy alone or in combination with cetuximab...
  49. ncbi request reprint Biology of interactions: antiepidermal growth factor receptor agents
    Paul M Harari
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    J Clin Oncol 25:4057-65. 2007
    ..Many questions remain to be answered, particularly with regard to how best combine EGFR inhibitors with conventional cancer therapies, and how to select those patients (tumors) most likely to benefit from EGFR inhibition strategies...
  50. ncbi request reprint More on severe cutaneous reaction with radiotherapy and cetuximab
    James A Bonner
    N Engl J Med 357:1872-3; author reply 1873. 2007
  51. ncbi request reprint Intraoperative radiotherapy for head and neck and skull base cancer
    A Daniel Pinheiro
    Department of Otorhinolaryngology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Head Neck 25:217-25; discussion 225-6. 2003
    ..The purpose of this study was to evaluate the use of intraoperative electron beam radiotherapy (IORT) as an adjuvant modality in the treatment of advanced head and neck and skull base cancer...
  52. ncbi request reprint Postoperative radiotherapy in non-small-cell lung cancer warrants further exploration in the era of adjuvant chemotherapy and conformal radiotherapy
    James A Bonner
    J Clin Oncol 24:2978-80. 2006
  53. ncbi request reprint A phase III study of surgical resection and paclitaxel/carboplatin chemotherapy with or without adjuvant radiation therapy for resected stage III non-small-cell lung cancer: Cancer and Leukemia Group B 9734
    Michael C Perry
    University of Missouri Ellis Fischel Cancer Center, Columbia, MO 65203, USA
    Clin Lung Cancer 8:268-72. 2007
    ..We added adjuvant chemotherapy to control presumed micrometastatic disease and then randomized patients to receive radiation therapy (RT) or observation to determine the benefit of local radiation consolidation...
  54. ncbi request reprint Patterns of surgical care of lung cancer patients
    Alex G Little
    Department of Surgery, Wright State University School of Medicine, Dayton, Ohio, USA
    Ann Thorac Surg 80:2051-6; discussion 2056. 2005
    ..This survey was performed to determine the patterns of surgical care provided patients with non-small cell lung carcinoma (NSCLC)...
  55. ncbi request reprint A quality-adjusted reanalysis of a Phase III trial comparing once-daily thoracic radiation vs. twice-daily thoracic radiation in patients with limited-stage small-cell lung cancer(1)
    Jeff A Sloan
    Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 52:371-81. 2002
    ....
  56. ncbi request reprint Quality of life in 650 lung cancer survivors 6 months to 4 years after diagnosis
    Adam Svobodnik
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    Mayo Clin Proc 79:1024-30. 2004
    ..To present the results of a quality-of-life (QOL) assessment performed with the current version of the Lung Cancer Symptom Scale (LCSS) questionnaire in a large single-institutional data set of 650 patients with lung cancer...
  57. ncbi request reprint Long-term results of a phase III trial comparing once-daily radiotherapy with twice-daily radiotherapy in limited-stage small-cell lung cancer
    Steven E Schild
    Mayo Clinic and Mayo Foundation, Rochester, MN, USA
    Int J Radiat Oncol Biol Phys 59:943-51. 2004
    ..This Phase III study was performed to determine whether twice-daily (b.i.d.) radiotherapy (RT) resulted in better survival than once-daily (q.d.) RT for patients with limited-stage small-cell lung cancer (LD-SCLC)...
  58. ncbi request reprint Smoking behavior of 226 patients with diagnosis of stage IIIA/IIIB non-small cell lung cancer
    Lisa Sanderson Cox
    Nicotine Research Program, Mayo Clinic, Rochester, MN 55905, USA
    Psychooncology 11:472-8. 2002
    ..Smoking cessation interventions are needed for lung cancer patients who continue to smoke...
  59. ncbi request reprint The outcome of combined-modality therapy for stage III non-small-cell lung cancer in the elderly
    Steven E Schild
    Mayo Clinic and Mayo Foundation, Rochester, MN, USA
    J Clin Oncol 21:3201-6. 2003
    ..No difference in survival was identified between the two arms. This secondary analysis was performed to examine the relationship between patient age and outcome...
  60. ncbi request reprint Epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib, and concurrent 5-fluorouracil, cisplatin and radiotherapy for patients with esophageal cancer: a phase I study
    Michael C Dobelbower
    University of Alabama at Birmingham, Alabama 35249 6832, USA
    Anticancer Drugs 17:95-102. 2006
    ..The major toxicities encountered were grade 1-2 diarrhea, grade 1 skin rash, grade 1-3 nausea and grade 3 dehydration. A phase II study is planned...