Marcelo G Bonini
Affiliation: University of Illinois at Chicago
Baig M, Zaichick S, Mao M, de Abreu A, Bakhshi F, Hart P, et al
. NOS1-derived nitric oxide promotes NF-ÎºB transcriptional activity through inhibition of suppressor of cytokine signaling-1. J Exp Med. 2015;212:1725-38 pubmed publisher
..These findings demonstrate a fundamental role for NOS1-derived NO in regulating TLR4-mediated inflammatory gene transcription, as well as the intensity and duration of the resulting host immune response. ..
SchlÃ¤pfer M, Piegeler T, Dull R, Schwartz D, Mao M, Bonini M, et al
. Propofol increases morbidity and mortality in a rat model of sepsis. Crit Care. 2015;19:45 pubmed publisher
..The main mechanism responsible for adverse propofol effects could be an enhanced plasma endotoxin concentration, leading to profound hypotension, which was unresponsive to fluid resuscitation. ..
He C, Hart P, Germain D, Bonini M. SOD2 and the Mitochondrial UPR: Partners Regulating Cellular Phenotypic Transitions. Trends Biochem Sci. 2016;41:568-577 pubmed publisher
Ekoue D, Zaichick S, Valyi Nagy K, PICKLO M, Lacher C, HOSKINS K, et al
. Selenium levels in human breast carcinoma tissue are associated with a common polymorphism in the gene for SELENOP (Selenoprotein P). J Trace Elem Med Biol. 2017;39:227-233 pubmed publisher
..Furthermore, the obtained data provide evidence for the need to obtain data about the effects of selenium in breast cancer by examining samples from that particular tissue type. ..
Ekoue D, He C, Diamond A, Bonini M. Manganese superoxide dismutase and glutathione peroxidase-1 contribute to the rise and fall of mitochondrial reactive oxygen species which drive oncogenesis. Biochim Biophys Acta Bioenerg. 2017;1858:628-632 pubmed publisher
..This article is part of a Special Issue entitled Mitochondria in Cancer, edited by Giuseppe Gasparre, Rodrigue Rossignol and Pierre Sonveaux. ..
Blajszczak C, Bonini M. Mitochondria targeting by environmental stressors: Implications for redox cellular signaling. Toxicology. 2017;391:84-89 pubmed publisher
..e. heavy metals) on the regulation of mitochondrial ROS (mtROS) production and subsequent impact. ..