M Bogyo

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs
    M Bogyo
    Departments of Biochemistry and Biophysics, University of California, San Francisco, CA 94143, USA
    Chem Biol 7:27-38. 2000
  2. pmc Global analysis of proteasomal substrate specificity using positional-scanning libraries of covalent inhibitors
    T Nazif
    Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 98:2967-72. 2001
  3. ncbi request reprint Defining a link between gap junction communication, proteolysis, and cataract formation
    A Baruch
    Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143, USA
    J Biol Chem 276:28999-9006. 2001
  4. ncbi request reprint Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense
    C R Caffrey
    Tropical Disease Research Unit, Department of Pathology, University of California San Francisco, VAMC, 4150 Clement Street-113B, San Francisco, CA 94121, USA
    Mol Biochem Parasitol 118:61-73. 2001
  5. ncbi request reprint Proteasome inhibitors: complex tools for a complex enzyme
    M Bogyo
    Department of Biochemistry and Biophysics, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, USA
    Curr Top Microbiol Immunol 268:185-208. 2002
  6. ncbi request reprint O-sulfonation of serine and threonine: mass spectrometric detection and characterization of a new posttranslational modification in diverse proteins throughout the eukaryotes
    K F Medzihradszky
    Department of Pharmaceutical Chemistry and Mass Spectrometry Facility, University of California, San Francisco, CA 94143, USA
    Mol Cell Proteomics 3:429-40. 2004

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs
    M Bogyo
    Departments of Biochemistry and Biophysics, University of California, San Francisco, CA 94143, USA
    Chem Biol 7:27-38. 2000
    ..A high degree of homology between family members and overlap in substrate specificity have made elucidating individual protease function, expression and activity difficult...
  2. pmc Global analysis of proteasomal substrate specificity using positional-scanning libraries of covalent inhibitors
    T Nazif
    Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 98:2967-72. 2001
    ..Finally, specificity profiles were used to design specific inhibitors of a single active site in the complex. These reagents can be used to further establish the role of each subunit in substrate processing by the proteasome...
  3. ncbi request reprint Defining a link between gap junction communication, proteolysis, and cataract formation
    A Baruch
    Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143, USA
    J Biol Chem 276:28999-9006. 2001
    ....
  4. ncbi request reprint Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense
    C R Caffrey
    Tropical Disease Research Unit, Department of Pathology, University of California San Francisco, VAMC, 4150 Clement Street-113B, San Francisco, CA 94121, USA
    Mol Biochem Parasitol 118:61-73. 2001
    ..S2 subsite mapping of rhodesain and cruzain with fluorogenic peptidyl substrates demonstrates that the presence of alanine rather than glutamate at S2 prevents rhodesain from cleaving substrates in which P2 is arginine...
  5. ncbi request reprint Proteasome inhibitors: complex tools for a complex enzyme
    M Bogyo
    Department of Biochemistry and Biophysics, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, USA
    Curr Top Microbiol Immunol 268:185-208. 2002
    ..It may only be a short while before the products of such research have safe application in a practical setting. Structural and combinatorial chemistry approaches are powerful techniques that will bring us closer to these goals...
  6. ncbi request reprint O-sulfonation of serine and threonine: mass spectrometric detection and characterization of a new posttranslational modification in diverse proteins throughout the eukaryotes
    K F Medzihradszky
    Department of Pharmaceutical Chemistry and Mass Spectrometry Facility, University of California, San Francisco, CA 94143, USA
    Mol Cell Proteomics 3:429-40. 2004
    ..These findings suggest that sulfonation of serine and threonine may be involved in multiple functions including protein assembly and signal transduction...