Research Topics
Species | K A BoggessSummaryAffiliation: University of North Carolina Country: USA Publications
Research Grants
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Detail Information
Publications
Vitamin D status and periodontal disease among pregnant womenKim A Boggess
Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
J Periodontol 82:195-200. 2011..The objective of this study is to examine the relationship between maternal vitamin D status and periodontal disease...
Insulin-like growth factor and interleukin-1beta levels and subsequent fetal size in response to chronic Porphyromonas gingivalis exposure in the pregnant rabbitKim A Boggess
Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill School of Medicine, 27599, USA
Am J Obstet Gynecol 193:1219-23. 2005..The purpose of this study was to describe maternal insulin-like growth factor, interleukin-1beta, and fetal size in a rabbit model of Porphyromonas gingivalis exposure...- Pathophysiology of preterm birth: emerging concepts of maternal infectionKim A Boggess
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of North Carolina School of Medicine, CB 7516, Chapel Hill, NC 27599 7516, USA
Clin Perinatol 32:561-9. 2005..Maternal oral infection such as clinical periodontal disease has also been identified as a risk factor for preterm birth, and pilot data suggest that oral treatment interventions undertaken during pregnancy may reduce preterm birth risk... - Chronic maternal and fetal Porphyromonas gingivalis exposure during pregnancy in rabbitsKim A Boggess
Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, NC, USA
Am J Obstet Gynecol 192:554-7. 2005..This study was undertaken to develop a rabbit model of maternal exposure to Porphyromonas gingivalis and determine whether fetal or placental exposure occurs... 
Oral health in women during preconception and pregnancy: implications for birth outcomes and infant oral healthKim A Boggess
Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill School of Medicine, CB 7516, Chapel Hill, North Carolina 27599 7516, USA
Matern Child Health J 10:S169-74. 2006..Oral health promotion should include education of women and their health care providers ways to prevent oral disease from occurring, and referral for dental services when disease is present...- Maternal oral health in pregnancyKim A Boggess
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA
Obstet Gynecol 111:976-86. 2008..Research is ongoing to delineate the role of maternal oral health care in pregnancy outcomes and opportunities for positive intervention... - Maternal periodontal disease is associated with an increased risk for preeclampsiaKim A Boggess
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, North Carolina 27599, USA
Obstet Gynecol 101:227-31. 2003..To determine if maternal periodontal disease is associated with the development of preeclampsia... - Fetal immune response to oral pathogens and risk of preterm birthKim A Boggess
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of North Carolina School of Medicine, Chapel Hill 27599 7516, USA
Am J Obstet Gynecol 193:1121-6. 2005..The purpose of this study was to determine the relationship between fetal inflammatory and immune responses to oral pathogens and risk for preterm birth... - Oral hygiene practices and dental service utilization among pregnant womenKim A Boggess
Department of Obstetrics and Gynecology, School of Medicine, University of North Carolina at Chapel Hill, CB 7516, Chapel Hill, NC 27599, USA
J Am Dent Assoc 141:553-61. 2010..Daily oral hygiene and regular dental visits are important components of oral health care. The authors' objective in this study was to examine women's oral hygiene practices and use of dental services during pregnancy... - Antepartum or postpartum isoniazid treatment of latent tuberculosis infectionK A Boggess
Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA
Obstet Gynecol 96:757-62. 2000..To compare health outcomes and costs of different strategies for treatment of latent tuberculosis infection in pregnancy... - Maternal periodontitis and prematurity. Part II: Maternal infection and fetal exposureP N Madianos
Center for Oral and Systemic Diseases, Departments of Periodontology and Dental Ecology, University of North Carolina at Chapel Hill, School of Dentistry, Chapel Hill, NC, USA
Ann Periodontol 6:175-82. 2001..The high prevalence of elevated fetal IgM to C. rectus among premature infants raises the possibility that this specific maternal oral pathogen may serve as a primary fetal infectious agent eliciting prematurity... - Fetal exposure to oral pathogens and subsequent risk for neonatal intensive care admissionHeather Jared
Department of Dental Ecology, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
J Periodontol 80:878-83. 2009..The objective of this study was to determine the relationship between fetal exposure to oral pathogens and neonatal intensive care unit (NICU) admission... - Maternal serum C-reactive protein concentration early in pregnancy and subsequent pregnancy lossKim A Boggess
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, North Carolina 27599, USA
Am J Perinatol 22:299-304. 2005..Future study should be directed at determining the role of maternal inflammation during early pregnancy development and placentation... - Maternal periodontitis and prematurity. Part I: Obstetric outcome of prematurity and growth restrictionS Offenbacher
Center for Oral and Systemic Diseases, Departments of Periodontology and Dental Ecology, University of North Carolina at Chapel Hill, School of Dentistry, Chapel Hill, NC, USA
Ann Periodontol 6:164-74. 2001..These studies underscore the need for further consideration of periodontal disease as a potentially new and modifiable risk for preterm birth and growth restriction... - Repeated fetal betamethasone treatment and birth weight and head circumferenceS D Shelton
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA
Obstet Gynecol 97:301-4. 2001..To assess the effect of repeated courses of betamethasone on birth weight and head circumference... - Altered expression of TCR-CD3zeta induced by sera from women with preeclampsiaP W Whitecar
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill School of Medicine, NC 27599-7516, USA
Am J Obstet Gynecol 185:812-8. 2001..This occurs remotely from the manifestation of clinical disease and suggests a deficiency in a serum factor in preeclampsia that may induce T cell zeta chain suppression in normal pregnancy... - Periodontal disease, oxidative stress, and risk for preeclampsiaAmanda L Horton
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of North Carolina, Chapel Hill, NC 27599 7516, USA
J Periodontol 81:199-204. 2010..The presence of periodontal disease did not appear to modify this risk... - Antepartum vaginal bleeding, fetal exposure to oral pathogens, and risk for preterm birth at <35 weeks of gestationKim A Boggess
Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC, USA
Am J Obstet Gynecol 194:954-60. 2006..6-16.0). CONCLUSION: Vaginal bleeding is associated with fetal exposure to oral pathogens, which increases preterm birth risk. Whether bleeding is the cause of or result of fetal exposure to oral pathogens remains to be determined... - Maternal serum granulocyte-colony stimulating factor in preterm birth with subclinical chorioamnionitisK A Boggess
Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC 27710, USA
J Reprod Immunol 33:45-52. 1997..Our data support this concept, as maternal serum G-CSF is elevated with subclinical infection in association with preterm birth... - The effect of teenage maternal obesity on perinatal outcomesSina Haeri
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7516, USA
Obstet Gynecol 113:300-4. 2009..To estimate the effect of obesity on perinatal outcomes among inner-city teenage pregnant women... - The oral conditions and pregnancy study: periodontal status of a cohort of pregnant womenSusan Lieff
University of North Carolina, Department of Dental Ecology and Center for Oral and Systemic Diseases, Chapel Hill, NC, USA
J Periodontol 75:116-26. 2004..Our objective was to describe the oral health of pregnant women, to determine oral health changes during pregnancy, and to determine factors associated with maternal periodontal health or disease... - Progressive periodontal disease and risk of very preterm deliverySteven Offenbacher
Department of Periodontology, Center for Oral and Systemic Diseases, University of North Carolina School of Dentistry, Chapel Hill, North Carolina 27599 7455, USA
Obstet Gynecol 107:29-36. 2006..The goal was to estimate whether maternal periodontal disease was predictive of preterm (less than 37 weeks) or very preterm (less than 32 weeks) births... - Maternal periodontal disease and soluble fms-like tyrosine kinase-1 expressionAmanda L Horton
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of North Carolina, Chapel Hill, NC, USA
J Periodontol 80:1506-10. 2009..This study was conducted to examine the relationship between maternal periodontal disease and plasma angiogenic factor expression of soluble fms-like tyrosine kinase (sFlt)-1... - Periodontal disease early in pregnancy is associated with maternal systemic inflammation among African American womenAmanda L Horton
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of North Carolina, Chapel Hill, NC 27599 7516, USA
J Periodontol 79:1127-32. 2008.... - Association of midgestational paraoxonase 1 activity with pregnancies complicated by preeclampsiaArthur M Baker
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, North Carolina 27599 7516, USA
Am J Perinatol 27:205-10. 2010..Prospective studies are needed to determine the significance of paraoxonase 1 in the pathogenesis of preeclampsia... - Differential expression of TcR-CD3 zeta as evidence for altered immunoregulation in preeclamptic versus normotensive womenGarrett K Lam
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, USA
Am J Obstet Gynecol 189:843-7. 2003..The study was undertaken to exhibit and quantify the difference in modulation of CD3-zeta protein (an integral component of the T-cell receptor) in preeclamptic and normotensive women... - Pathogenicity of periodontal pathogens during pregnancyKim A Boggess
Department of OB/BYN, University of North Carolina, Chapel Hill 27599, USA
Am J Obstet Gynecol 193:311-2. 2005 - Umbilical venous D-dimer concentrations with and without laborA P Murtha
Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina 27710, USA
Obstet Gynecol 92:184-6. 1998..To determine if labor activates the fetal fibrinolytic system... - Maternal periodontal disease in early pregnancy and risk for a small-for-gestational-age infantKim A Boggess
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC, USA
Am J Obstet Gynecol 194:1316-22. 2006..Understanding the mechanism of periodontal disease-associated adverse pregnancy outcomes could lead to interventions to improve fetal growth... 
Maternal antenatal complications and the risk of neonatal cerebral white matter damage and later cerebral palsy in children born at an extremely low gestational ageThomas F McElrath
Division of Maternal Fetal Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
Am J Epidemiol 170:819-28. 2009....- Prevalence of Epstein-Barr virus reactivation in pregnancySina Haeri
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599 7516, USA
Am J Perinatol 27:715-9. 2010..The pathophysiology and clinical implications of EBV reactivation during pregnancy need further study... - Bacterial infection promotes DNA hypermethylationY A Bobetsis
University of North Carolina at Chapel Hill, Center for Oral and Systemic Diseases, Department of Periodontology, UNC School of Dentistry, CB 7455, DRC Rm 222, Chapel Hill, NC 27599 7455, USA
J Dent Res 86:169-74. 2007..This novel finding, correlating infection with epigenetic alterations, provides a mechanism linking environmental signals to placental phenotype, with consequences for development... - Urinary interleukin-8 with asymptomatic bacteriuria in pregnancyS D Shelton
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Durham, North Carolina, USA
Obstet Gynecol 97:583-6. 2001..To evaluate urinary interleukin-8 (IL-8), an inflammatory cytokine, as a screening method for detecting asymptomatic bacteriuria in pregnancy... - The clinical content of preconception care: infectious diseases in preconception careDean V Coonrod
Department of Obstetrics and Gynecology, Maricopa Medical Center, Phoenix, AZ 85008, USA
Am J Obstet Gynecol 199:S296-309. 2008.... - Periodontal disease increases the risk of preterm delivery among preeclamptic womenEstelle L Riché
Center for Oral and Systemic Diseases and Comprehensive Center for Inflammatory Disorders, School of Dentistry, University of North Carolina, Chapel Hill, North Carolina, USA
Ann Periodontol 7:95-101. 2002..Our current objective was to determine whether maternal periodontal disease increases the risk for preterm delivery among preeclamptic women... - Effect of betamethasone on maternal glucoseS D Shelton
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA
J Matern Fetal Neonatal Med 12:191-5. 2002..One-hour postprandial values were not clinically abnormal... - The effect of excess weight gain in teenage pregnanciesSina Haeri
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7516, USA
Am J Perinatol 27:15-8. 2010..We concluded that excess weight gain places teen mothers at increased risk for cesarean delivery, postpartum febrile morbidity, and macrosomia. Interventions aimed at optimal weight gain in teen pregnancies are warranted... - The clinical content of preconception care: immunizations as part of preconception careDean V Coonrod
Department of Obstetrics and Gynecology, Maricopa Medical Center, Phoenix, AZ 85008, USA
Am J Obstet Gynecol 199:S290-5. 2008..The role of human papillomavirus, varicella, diphtheria, tetanus, and pertussis vaccinations as part of preconception care is also discussed... - Racial differences in C-reactive protein levels during normal pregnancyAmy H Picklesimer
Department of Obstetrics and Gynecology, Greenville Hospital System University Medical Center, Greenville, SC, USA
Am J Obstet Gynecol 199:523.e1-6. 2008..The purpose of this study was to characterize serum C-reactive protein (CRP) levels in a diverse population of healthy pregnant women with the use of a high sensitivity assay... - Use of DNA hybridization to detect vaginal pathogens associated with bacterial vaginosis among asymptomatic pregnant womenKim A Boggess
Department of Obstetrics and Gynecology, and Center for Oral and Systemic Diseases; University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Am J Obstet Gynecol 193:752-6. 2005..001). CONCLUSION: DNA hybridization may be a useful method to study shifts in vaginal flora during pregnancy...
Research Grants
- EFFECT OF CHRONIC INFECTION ON PLACENTAL DEVELOPMENTKim Boggess; Fiscal Year: 2005..Understanding of these mechanisms may assist in the development of interventions to protect the fetus and placenta from damage as a result of chronic maternal infection with oral pathogens. ..
- Understanding Barriers to Oral Health Care In Pregnancy: The First Step to ImprovKim Boggess; Fiscal Year: 2007....