John F Boggess

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. doi request reprint A comparative study of 3 surgical methods for hysterectomy with staging for endometrial cancer: robotic assistance, laparoscopy, laparotomy
    John F Boggess
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA
    Am J Obstet Gynecol 199:360.e1-9. 2008
  2. doi request reprint A case-control study of robot-assisted type III radical hysterectomy with pelvic lymph node dissection compared with open radical hysterectomy
    John F Boggess
    Division of Gynecology Oncology, Department of Obstetrics and Gynecology, UNC School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Am J Obstet Gynecol 199:357.e1-7. 2008
  3. ncbi request reprint Estrogen-receptor-dependent regulation of telomerase activity in human endometrial cancer cell lines
    John F Boggess
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Gynecol Oncol 103:417-24. 2006
  4. doi request reprint Perioperative outcomes of robotically assisted hysterectomy for benign cases with complex pathology
    John F Boggess
    Department of Obstetrics and Gynecology, Division of Gynecology Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Obstet Gynecol 114:585-93. 2009
  5. pmc Rapamycin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and induction of apoptosis
    Aaron Shafer
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, North Carolina 27599 7572, USA
    Int J Cancer 126:1144-54. 2010
  6. ncbi request reprint Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest
    Victoria L Bae-Jump
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, CB 7570, Chapel Hill, NC 27599, USA
    Gynecol Oncol 100:487-94. 2006
  7. doi request reprint Rapamycin inhibits cell proliferation in type I and type II endometrial carcinomas: a search for biomarkers of sensitivity to treatment
    Victoria L Bae-Jump
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Gynecol Oncol 119:579-85. 2010
  8. ncbi request reprint Consolidation therapy with weekly paclitaxel infusion in advanced epithelial ovarian cancer and primary peritoneal cancer: an extended follow-up
    Elizabeth N Skinner
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC 27599, USA
    Gynecol Oncol 98:59-62. 2005
  9. doi request reprint Synergistic effect of rapamycin and cisplatin in endometrial cancer cells
    Victoria L Bae-Jump
    Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC, USA
    Cancer 115:3887-96. 2009
  10. ncbi request reprint The PTEN tumor suppressor inhibits telomerase activity in endometrial cancer cells by decreasing hTERT mRNA levels
    Chunxiao Zhou
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of North Carolina at Chapel Hill, CB 7570, Chapel Hill, NC 27599, USA
    Gynecol Oncol 101:305-10. 2006

Collaborators

Detail Information

Publications33

  1. doi request reprint A comparative study of 3 surgical methods for hysterectomy with staging for endometrial cancer: robotic assistance, laparoscopy, laparotomy
    John F Boggess
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA
    Am J Obstet Gynecol 199:360.e1-9. 2008
    ..The purpose of this study was to compare outcomes in women who underwent endometrial cancer staging by different surgical techniques...
  2. doi request reprint A case-control study of robot-assisted type III radical hysterectomy with pelvic lymph node dissection compared with open radical hysterectomy
    John F Boggess
    Division of Gynecology Oncology, Department of Obstetrics and Gynecology, UNC School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Am J Obstet Gynecol 199:357.e1-7. 2008
    ..The purpose of this study was to compare robotically assisted hysterectomy (RAH) with open (ORH) type III radical hysterectomy in the treatment of early-stage cervical cancer...
  3. ncbi request reprint Estrogen-receptor-dependent regulation of telomerase activity in human endometrial cancer cell lines
    John F Boggess
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Gynecol Oncol 103:417-24. 2006
    ....
  4. doi request reprint Perioperative outcomes of robotically assisted hysterectomy for benign cases with complex pathology
    John F Boggess
    Department of Obstetrics and Gynecology, Division of Gynecology Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Obstet Gynecol 114:585-93. 2009
    ..To report on the perioperative outcomes after robotically assisted total hysterectomy for benign indications in a large patient population with predominantly complex pathology...
  5. pmc Rapamycin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and induction of apoptosis
    Aaron Shafer
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, North Carolina 27599 7572, USA
    Int J Cancer 126:1144-54. 2010
    ..This suggests that the combination of rapamycin and paclitaxel may be a promising effective targeted therapy for endometrial cancer...
  6. ncbi request reprint Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest
    Victoria L Bae-Jump
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, CB 7570, Chapel Hill, NC 27599, USA
    Gynecol Oncol 100:487-94. 2006
    ..Our goal was to examine the ability of rapamycin to suppress growth and regulate telomerase activity in cervical and ovarian cancer cell lines...
  7. doi request reprint Rapamycin inhibits cell proliferation in type I and type II endometrial carcinomas: a search for biomarkers of sensitivity to treatment
    Victoria L Bae-Jump
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Gynecol Oncol 119:579-85. 2010
    ..Our goal was to evaluate the effect of rapamycin, an mTOR inhibitor, in type I and II human endometrial cancer tumor explants...
  8. ncbi request reprint Consolidation therapy with weekly paclitaxel infusion in advanced epithelial ovarian cancer and primary peritoneal cancer: an extended follow-up
    Elizabeth N Skinner
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC 27599, USA
    Gynecol Oncol 98:59-62. 2005
    ..To determine the impact of weekly paclitaxel consolidation on progression-free survival (PFS) of women undergoing treatment for ovarian cancer...
  9. doi request reprint Synergistic effect of rapamycin and cisplatin in endometrial cancer cells
    Victoria L Bae-Jump
    Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC, USA
    Cancer 115:3887-96. 2009
    ..Because rapamycin is known to enhance the cytotoxicity of chemotherapeutic drugs, the authors' goal was to examine the effects of rapamycin and cisplatin in endometrial cancer cell lines...
  10. ncbi request reprint The PTEN tumor suppressor inhibits telomerase activity in endometrial cancer cells by decreasing hTERT mRNA levels
    Chunxiao Zhou
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of North Carolina at Chapel Hill, CB 7570, Chapel Hill, NC 27599, USA
    Gynecol Oncol 101:305-10. 2006
    ..Given that PTEN is often absent and telomerase is overexpressed by endometrial cancers, we hypothesize that PTEN signaling is important in telomerase regulation...
  11. doi request reprint Survival outcomes for women undergoing type III robotic radical hysterectomy for cervical cancer: a 3-year experience
    Leigh A Cantrell
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of North Carolina, Chapel Hill, NC 27599 7572, USA
    Gynecol Oncol 117:260-5. 2010
    ..Longer follow-up is needed, but early data are supportive of at least equivalent oncologic outcomes compared with other surgical modalities...
  12. doi request reprint Recurrence-free and 5-year survival following robotic-assisted surgical staging for endometrial carcinoma
    Joshua E Kilgore
    Division of Gynecologic Oncology, University of North Carolina, Chapel Hill, NC, USA
    Gynecol Oncol 129:49-53. 2013
    ..The aim of this study is to report recurrence-free and overall survival for women with endometrial adenocarcinoma who were surgically staged using robotic-assisted laparoscopy...
  13. ncbi request reprint Induction of apoptosis and inhibition of telomerase activity by arsenic trioxide (As2O3) in endometrial carcinoma cells
    Chunxiao Zhou
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, CB 7570 MacNider Building, Chapel Hill, NC 27599 7570, USA
    Gynecol Oncol 105:218-22. 2007
    ..To examine the effects of arsenic trioxide (As2O3) on human endometrial carcinoma cell lines with respect to cytotoxicity and the induction of apoptosis and telomerase expression in vitro...
  14. ncbi request reprint Uterine serous and grade 3 endometrioid carcinomas: is there a survival difference?
    David M Boruta
    Department of Obstetrics and Gynecology, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599, USA
    Cancer 101:2214-21. 2004
    ....
  15. doi request reprint Arsenic trioxide (As2O3) inhibits expression of estrogen receptor-alpha through regulation of the mitogen-activated protein kinase (MAPK) pathway in endometrial cancer cells
    Victoria L Bae-Jump
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Reprod Sci 15:1011-7. 2008
    ..Thus, As(2)O(3) may be valuable for its anti-estrogenic activity in combination with its anti-tumorigenic effects and be a novel therapeutic agent for endometrial cancer...
  16. pmc Estrogen induction of telomerase activity through regulation of the mitogen-activated protein kinase (MAPK) dependent pathway in human endometrial cancer cells
    Chunxiao Zhou
    Division of Gynecological Oncology, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, North Carolina, USA
    PLoS ONE 8:e55730. 2013
    ..These findings suggest that E2-induction of telomerase activity is mediated via the MAPK pathway in human endometrial cancer cells...
  17. doi request reprint What is the optimal minimally invasive surgical procedure for endometrial cancer staging in the obese and morbidly obese woman?
    Paola A Gehrig
    Division of Gynecologic Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Gynecol Oncol 111:41-5. 2008
    ..We sought to compare minimally invasive surgical techniques for staging the obese and morbidly obese woman with endometrial cancer...
  18. doi request reprint Robotic-assisted endometrial cancer staging and radical hysterectomy with the da Vinci surgical system
    Aaron Shafer
    Division of Gynecologic Oncology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Gynecol Oncol 111:S18-23. 2008
    ..The applications of robotic-assisted surgery are rapidly being incorporated into the field of gynecologic oncology...
  19. doi request reprint Outpatient end of life discussions shorten hospital admissions in gynecologic oncology patients
    Kemi M Doll
    Division of Gynecologic Oncology, University of North Carolina, Chapel Hill, NC, United States
    Gynecol Oncol 130:152-5. 2013
    ..The study goal was to determine whether prior outpatient exposure to hospice discussion altered the inpatient course and end-of-life (EOL) care among patients ultimately discharged to hospice...
  20. doi request reprint Physical strain and urgent need for ergonomic training among gynecologic oncologists who perform minimally invasive surgery
    Jason Franasiak
    Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7570, USA
    Gynecol Oncol 126:437-42. 2012
    ..There is limited data regarding physical strain and minimally invasive gynecologic surgery (MIS). We sought to evaluate ergonomic strain among gynecologic oncologists...
  21. ncbi request reprint Rapamycin inhibits telomerase activity by decreasing the hTERT mRNA level in endometrial cancer cells
    Chunxiao Zhou
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Mol Cancer Ther 2:789-95. 2003
    ..This work suggests that rapamycin is a potentially useful targeted therapy for endometrial cancer and that loss of telomerase activity may be a good surrogate biomarker for assessing antitumor activity of rapamycin...
  22. ncbi request reprint Association between uterine serous carcinoma and breast cancer
    Paola A Gehrig
    Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC 27599 7570, USA
    Gynecol Oncol 94:208-11. 2004
    ....
  23. doi request reprint Robotically assisted fluorescence-guided lymph node mapping with ICG for gynecologic malignancies: a feasibility study
    Emma C Rossi
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, USA
    Gynecol Oncol 124:78-82. 2012
    ..We performed a feasibility and dose-finding study to define the dose of ICG required to identify pelvic and para-aortic sentinel lymph nodes with robotically assisted endoscopic NIR imaging after cervical injection...
  24. doi request reprint Efficacy and safety of imatinib mesylate (Gleevec) and immunohistochemical expression of c-Kit and PDGFR-beta in a Gynecologic Oncology Group Phase Il Trial in women with recurrent or persistent carcinosarcomas of the uterus
    Warner K Huh
    Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, AL, USA
    Gynecol Oncol 117:248-54. 2010
    ..This multi-institutional phase II trial assessed the activity and toxicity of imatinib mesylate and explored c-Kit and platelet-derived growth factor receptor (PDGFR)-beta in recurrent or persistent uterine carcinosarcoma...
  25. ncbi request reprint The use of non-nutritive sucking to decrease the physiologic pain response during neonatal circumcision: a randomized controlled trial
    Mary M T South
    Department of Obstetrics and Gynecology, University of North Carolina Hospitals, Chapel Hill, NC 27514, USA
    Am J Obstet Gynecol 193:537-42; discussion 542-3. 2005
    ..The purpose of this research was to study the effects on the physiologic pain response of the neonate during circumcision with the use of a gloved human finger...
  26. doi request reprint Utility of the omentum in pelvic floor reconstruction following resection of anorectal malignancy: patient selection, technical caveats, and clinical outcomes
    Charles S Hultman
    Division of Plastic Surgery, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Ann Plast Surg 64:559-62. 2010
    ....
  27. doi request reprint Management of a persistent adnexal mass in pregnancy: what is the ideal surgical approach?
    Ursula Balthazar
    Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7570, USA
    J Minim Invasive Gynecol 18:720-5. 2011
    ..To compare short-term and pregnancy-related outcomes of laparoscopy with laparotomy for management of a persistent second-trimester adnexal mass...
  28. doi request reprint Emergence of robotic assisted surgery in gynecologic oncology: American perspective
    Alberto Mendivil
    University of North Carolina, Chapel Hill, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, 101 Manning Drive, CB 7572, Chapel Hill, NC 27599 7572 USA
    Gynecol Oncol 114:S24-31. 2009
    ..To discuss the emergence of robotic surgery in gynecologic oncology and describe the growth of robotic surgery in a university medical center and a community based practice...
  29. doi request reprint Robotic resection of adnexal masses during pregnancy
    Kacey Y Eichelberger
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC 27599, USA
    Am J Perinatol 30:371-5. 2013
    ..To characterize the safety and feasibility of robotic adnexal surgery during pregnancy, and to compare surgical and obstetric outcomes for robotic versus laparoscopic treatment of adnexal masses during pregnancy...
  30. ncbi request reprint EGFR expression and HER2/neu overexpression/amplification in endometrial carcinosarcoma
    Chad A Livasy
    Department of Pathology and Lab Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Gynecol Oncol 100:101-6. 2006
    ..The aim of this study was to evaluate for HER2 and EGFR expression in cases of endometrial carcinosarcoma...
  31. ncbi request reprint Weekly paclitaxel infusion as salvage therapy in ovarian cancer
    David M Boruta
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of North Carolina, Campus Box 7570, 4013 Old Clinic Building, Chapel Hill, NC 27599 7570, USA
    Cancer Invest 21:675-81. 2003
    ..The regimen is well tolerated with no cases of grade 4 neutropenia or worsening neuropathy in our population...
  32. doi request reprint Robotic surgical training program in gynecology: how to train residents and fellows
    Elizabeth J Geller
    Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, NC 27599 7570, USA
    J Minim Invasive Gynecol 18:224-9. 2011
    ..Resident and fellow instruction in new surgical technology is an important part of training in obstetrics and gynecology. Herein is reported a method to accomplish robotic training that standardizes instruction and assessment of skills...
  33. ncbi request reprint Phase III study of cisplatin with or without paclitaxel in stage IVB, recurrent, or persistent squamous cell carcinoma of the cervix: a gynecologic oncology group study
    David H Moore
    Indiana University School of Medicine, 3535 Barnhill Dr, RT433, Indianapolis, IN 46202 5274 e mail
    J Clin Oncol 22:3113-9. 2004
    ..Tumor measurements and quality-of-life (QOL) assessments were obtained before each treatment cycle...