Vijay Boggaram

Summary

Affiliation: University of Texas Health Center
Country: USA

Publications

  1. pmc Early secreted antigenic target of 6 kDa (ESAT-6) protein of Mycobacterium tuberculosis induces interleukin-8 (IL-8) expression in lung epithelial cells via protein kinase signaling and reactive oxygen species
    Vijay Boggaram
    Department of Cell and Molecular Biology and the Center for Pulmonary Infectious Disease Control, University of Texas Health Science Center, Tyler, Texas 75708 3154, USA
    J Biol Chem 288:25500-11. 2013
  2. pmc Transcriptional regulation of SP-B gene expression by nitric oxide in H441 lung epithelial cells
    Vijay Boggaram
    Center for Biomedical Research, Univ of Texas Health Science Center at Tyler, TX 75708 3154, USA
    Am J Physiol Lung Cell Mol Physiol 299:L252-62. 2010
  3. doi request reprint Thyroid transcription factor-1 (TTF-1/Nkx2.1/TITF1) gene regulation in the lung
    Vijay Boggaram
    Department of Molecular Biology, The University of Texas Health Science Center at Tyler, 11937 US Highway 271, Tyler, TX 75708 3154, USA
    Clin Sci (Lond) 116:27-35. 2009
  4. ncbi request reprint Regulation of lung surfactant protein gene expression
    Vijay Boggaram
    Department of Molecular Biology, University of Texas Health Center at Tyler, 11937, US Highway 271, Tyler, TX 75708 3154, USA
    Front Biosci 8:d751-64. 2003
  5. ncbi request reprint Regulation of surfactant protein gene expression by hyperoxia in the lung
    Vijay Boggaram
    Department of Molecular Biology, The University of Texas Health Center at Tyler, Tyler, TX 75708 3154, USA
    Antioxid Redox Signal 6:185-90. 2004
  6. pmc Thyroid transcription factor-1 (TTF-1) gene: identification of ZBP-89, Sp1, and TTF-1 sites in the promoter and regulation by TNF-α in lung epithelial cells
    Aparajita Das
    Center for Biomedical Research, The University of Texas Health Center at Tyler, 75708 3154, USA
    Am J Physiol Lung Cell Mol Physiol 301:L427-40. 2011
  7. pmc Regulation of lung injury and fibrosis by p53-mediated changes in urokinase and plasminogen activator inhibitor-1
    Yashodhar P Bhandary
    Texas Lung Injury Institute, Center for Biomedical Research, University of Texas Health Science Center at Tyler, Tyler, Texas 75708, USA
    Am J Pathol 183:131-43. 2013
  8. ncbi request reprint Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity
    Loretta Sparkman
    Dept of Molecular Biology, University of Texas Health Center at Tyler, TX 75708 3154, USA
    Am J Physiol Lung Cell Mol Physiol 290:L351-8. 2006
  9. ncbi request reprint Proteasome dysfunction inhibits surfactant protein gene expression in lung epithelial cells: mechanism of inhibition of SP-B gene expression
    Aparajita Das
    Department of Molecular Biology, The University of Texas Health Center at Tyler, 11937 US Highway 271, Tyler, TX 75708 3154, USA
    Am J Physiol Lung Cell Mol Physiol 292:L74-84. 2007
  10. ncbi request reprint Nitric oxide increases IL-8 gene transcription and mRNA stability to enhance IL-8 gene expression in lung epithelial cells
    Loretta Sparkman
    Department of Molecular Biology, University of Texas Health Center at Tyler, Tyler, Texas 75708 3154, USA
    Am J Physiol Lung Cell Mol Physiol 287:L764-73. 2004

Collaborators

  • Sreerama Shetty
  • Gilbert F Morris
  • Hong Long Ji
  • Buka Samten
  • Aparajita Das
  • Loretta Sparkman
  • Hemakumar Chandru
  • Yashodhar P Bhandary
  • Darrell Salinas
  • Amarnath S Marudamuthu
  • Steven Idell
  • Pierre F Neuenschwander
  • Jian Fu
  • Koteswara Rao Gottipati
  • Sunil Acharya
  • Joseph L Alcorn
  • James B McKnight
  • Kiflu Berhane

Detail Information

Publications12

  1. pmc Early secreted antigenic target of 6 kDa (ESAT-6) protein of Mycobacterium tuberculosis induces interleukin-8 (IL-8) expression in lung epithelial cells via protein kinase signaling and reactive oxygen species
    Vijay Boggaram
    Department of Cell and Molecular Biology and the Center for Pulmonary Infectious Disease Control, University of Texas Health Science Center, Tyler, Texas 75708 3154, USA
    J Biol Chem 288:25500-11. 2013
    ..This has important implications for the understanding of lung innate immune responses to tuberculosis and the pathogenesis of lung injury in tuberculosis. ..
  2. pmc Transcriptional regulation of SP-B gene expression by nitric oxide in H441 lung epithelial cells
    Vijay Boggaram
    Center for Biomedical Research, Univ of Texas Health Science Center at Tyler, TX 75708 3154, USA
    Am J Physiol Lung Cell Mol Physiol 299:L252-62. 2010
    ..NO inhibits TTF-1 levels and activity to decrease SP-B expression. NO inhibition of SP-B expression could be a mechanism by which surfactant dysfunction occurs in inflammatory lung diseases...
  3. doi request reprint Thyroid transcription factor-1 (TTF-1/Nkx2.1/TITF1) gene regulation in the lung
    Vijay Boggaram
    Department of Molecular Biology, The University of Texas Health Science Center at Tyler, 11937 US Highway 271, Tyler, TX 75708 3154, USA
    Clin Sci (Lond) 116:27-35. 2009
    ..Recent studies have implicated TTF-1 as a lineage-specific proto-oncogene for lung cancer...
  4. ncbi request reprint Regulation of lung surfactant protein gene expression
    Vijay Boggaram
    Department of Molecular Biology, University of Texas Health Center at Tyler, 11937, US Highway 271, Tyler, TX 75708 3154, USA
    Front Biosci 8:d751-64. 2003
    ..Surfactant protein promoter function is dependent on the combinatorial actions of multiple transcription factors, and thyroid transcription factor 1 (TTF-1/Nkx2.1) is a common positive regulator of surfactant protein promoter activity...
  5. ncbi request reprint Regulation of surfactant protein gene expression by hyperoxia in the lung
    Vijay Boggaram
    Department of Molecular Biology, The University of Texas Health Center at Tyler, Tyler, TX 75708 3154, USA
    Antioxid Redox Signal 6:185-90. 2004
    ..A limited number of studies have indicated that the increased tissue expression of surfactant protein mRNAs is associated with increased levels of surfactant proteins in the bronchoalveolar lavage...
  6. pmc Thyroid transcription factor-1 (TTF-1) gene: identification of ZBP-89, Sp1, and TTF-1 sites in the promoter and regulation by TNF-α in lung epithelial cells
    Aparajita Das
    Center for Biomedical Research, The University of Texas Health Center at Tyler, 75708 3154, USA
    Am J Physiol Lung Cell Mol Physiol 301:L427-40. 2011
    ..Because TTF-1 serves as a positive regulator for surfactant protein gene expression, TNF-α inhibition of TTF-1 expression could have important implications for the reduction of surfactant protein levels in diseases such as ARDS...
  7. pmc Regulation of lung injury and fibrosis by p53-mediated changes in urokinase and plasminogen activator inhibitor-1
    Yashodhar P Bhandary
    Texas Lung Injury Institute, Center for Biomedical Research, University of Texas Health Science Center at Tyler, Tyler, Texas 75708, USA
    Am J Pathol 183:131-43. 2013
    ..Our findings indicate that disruption of p53-fibrinolytic system cross talk may serve as a novel intervention strategy to prevent lung injury and pulmonary fibrosis...
  8. ncbi request reprint Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity
    Loretta Sparkman
    Dept of Molecular Biology, University of Texas Health Center at Tyler, TX 75708 3154, USA
    Am J Physiol Lung Cell Mol Physiol 290:L351-8. 2006
    ..Chemical inhibitors of de novo ceramide synthesis and sphingomyelin hydrolysis had no effect on TNF-alpha inhibition of SP-B promoter activity and mRNA levels, suggesting that ceramide does not play a role in the inhibition...
  9. ncbi request reprint Proteasome dysfunction inhibits surfactant protein gene expression in lung epithelial cells: mechanism of inhibition of SP-B gene expression
    Aparajita Das
    Department of Molecular Biology, The University of Texas Health Center at Tyler, 11937 US Highway 271, Tyler, TX 75708 3154, USA
    Am J Physiol Lung Cell Mol Physiol 292:L74-84. 2007
    ....
  10. ncbi request reprint Nitric oxide increases IL-8 gene transcription and mRNA stability to enhance IL-8 gene expression in lung epithelial cells
    Loretta Sparkman
    Department of Molecular Biology, University of Texas Health Center at Tyler, Tyler, Texas 75708 3154, USA
    Am J Physiol Lung Cell Mol Physiol 287:L764-73. 2004
    ..NO induction of IL-8 gene expression could be a significant contributing factor in the initiation and induction of inflammatory response in the respiratory epithelium...
  11. ncbi request reprint Nitric oxide inhibits surfactant protein B gene expression in lung epithelial cells
    Darrell Salinas
    Department of Molecular Biology, University of Texas Health Center at Tyler, Tyler, Texas 75708 3154, USA
    Am J Physiol Lung Cell Mol Physiol 285:L1153-65. 2003
    ..These data imply that reduced SP-B expression due to elevated NO levels can contribute to lung injury...
  12. pmc The role of sphingosine 1-phosphate in the TNF-alpha induction of IL-8 gene expression in lung epithelial cells
    Hemakumar Chandru
    Department of Molecular Biology, University of Texas Health Center at Tyler, 11937 US Highway 271 Tyler, TX 75708 3154, USA
    Gene 391:150-60. 2007
    ..These data show that increases in the intracellular S1-P partly mediate TNF-alpha induction of IL-8 gene expression in H441 lung epithelial cells via ERK and p38 MAPK signaling pathways and increased AP-1 DNA binding...