Marco Boccitto

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Daf-2 signaling modifies mutant SOD1 toxicity in C. elegans
    Marco Boccitto
    Department of Pediatrics, Division of Neurology, Children s Hospital of Philadelphia Research Institute, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 7:e33494. 2012
  2. pmc Regulation of Foxo-dependent transcription by post-translational modifications
    Marco Boccitto
    Department of Pediatrics, Division of Neurology, Abramson Research Center, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Curr Drug Targets 12:1303-10. 2011
  3. pmc Stress and aging induce distinct polyQ protein aggregation states
    Lorenza E Moronetti Mazzeo
    Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 109:10587-92. 2012
  4. pmc Signaling events in axons and/or dendrites render motor neurons vulnerable to mutant superoxide dismutase toxicity
    Goo Bo Jeong
    Division of Neurology, Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 31:295-9. 2011

Collaborators

Detail Information

Publications4

  1. pmc Daf-2 signaling modifies mutant SOD1 toxicity in C. elegans
    Marco Boccitto
    Department of Pediatrics, Division of Neurology, Children s Hospital of Philadelphia Research Institute, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 7:e33494. 2012
    ..These results suggest that manipulation of the DAF-2 Insulin/IGF-1 signaling pathway may have therapeutic potential for the treatment of ALS...
  2. pmc Regulation of Foxo-dependent transcription by post-translational modifications
    Marco Boccitto
    Department of Pediatrics, Division of Neurology, Abramson Research Center, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Curr Drug Targets 12:1303-10. 2011
    ....
  3. pmc Stress and aging induce distinct polyQ protein aggregation states
    Lorenza E Moronetti Mazzeo
    Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 109:10587-92. 2012
    ..Our findings show that in vivo, the same protein can adopt distinct aggregation states depending on the initiating stressor and that stress and aging impact the proteome in related but distinct ways...
  4. pmc Signaling events in axons and/or dendrites render motor neurons vulnerable to mutant superoxide dismutase toxicity
    Goo Bo Jeong
    Division of Neurology, Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 31:295-9. 2011
    ..BDNF action depends upon endocytosis of the BDNF-TrkB complex and de novo protein synthesis. These results highlight the importance of signaling events occurring in axons/dendrites in mutant SOD toxicity...