Affiliation: University of Pittsburgh
- Treatment of colon and rectal cancerDavid Blumberg
Division of GI Surgical Oncology, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15261, USA
J Clin Gastroenterol 34:15-26. 2002..This review details many of these advances in a comprehensive manner and illustrates the necessity of a multidisciplinary approach for optimizing outcome for patients with these cancers...
- Surgery for ulcerative colitisDavid Blumberg
Department of Surgery, University of Pittsburgh Medical Center, 497 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA
Gastroenterol Clin North Am 31:219-35. 2002..A restorative proctocolectomy is the preferred surgical approach that not only cures the patient of the disease and prevents the development of colorectal cancer, but also maintains continence with an improved quality of life...
- Laparoscopic colectomy performed using a completely intracorporeal technique is associated with similar outcome in obese and thin patientsDavid Blumberg
Department of Surgery, University of Pittsburgh Medical Center and Bandaid Surgery, Pittsburgh, PA 15232, USA
Surg Laparosc Endosc Percutan Tech 19:57-61. 2009..Despite the potential benefits of laparoscopic-assisted colectomy, it is often associated with high operative conversion rates and increased morbidity especially in patients with obesity...
- Laparoscopic colon resection of benign polyps: high grade dysplasia on endoscopic biopsy and polyp location predict risk of cancerDavid Blumberg
Department of Surgery, University of Pittsburgh Medical Center and Bandaid Surgery, Pittsburgh, PA 15232, USA Bandaidsurgery com
Surg Laparosc Endosc Percutan Tech 19:255-7. 2009..A retrospective review was performed of laparoscopic resections for colonic polyps to determine the incidence of occult cancer and, clinical and pathologic factors predictive of cancer...
- Is operative conversion necessary for patients diagnosed with dense adhesions during an elective laparoscopic colectomy?David Blumberg
University of Pittsburgh Medical Center and Bandaid Surgery, Pittsburgh, Pennsylvania 15232, USA
Surg Innov 15:213-8. 2008..Laparoscopic colectomy is often complicated by adhesions. Studies examining the morbidity of laparoscopic lysis of adhesions (LOA) combined with colectomy are sparse...
- Nitric oxide and ionizing radiation synergistically promote apoptosis and growth inhibition of cancer by activating p53Tracy Cook
Department of Surgery and Center for Biologic Imaging, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15232, USA
Cancer Res 64:8015-21. 2004..Furthermore, the transfer of both p53 and iNOS genes into tumor cells lacking functional p53 enhanced their radioresponsiveness more than transfer of either gene alone...
- Prognostic significance of depth of gross or microscopic perirectal fat invasion in T3 N0 M0 rectal cancers following sharp mesorectal excision and no adjuvant therapyAntonio I Picon
Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, NY 10021, New York, USA
Int J Colorectal Dis 18:487-92. 2003..CONCLUSION. Our data suggest that the extent of gross, or microscopic perirectal fat invasion (defined as >3 or </=3 mm), determined in the resected specimen, does not predict outcome in select T3 N0 rectal cancers...
- Overexpression of the human inducible nitric oxide synthase gene enhances radiation-induced apoptosis in colorectal cancer cells via a caspase-dependent mechanismPeter Chung
Department of Surgery, University of Pittsburgh School of Medicine, Cancer Pavillion, 5150 Centre Avenue, Rm 438, Pittsburgh, PA 15232, USA
Nitric Oxide 8:119-26. 2003..Gene transfer of iNOS holds much promise as a potential radiosensitizer of cancer cells since it increases apoptosis in an additive manner with radiation...
- Long-term results of local excision for rectal cancerPhilip B Paty
Department of Surgery, Pathology, and Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Surg 236:522-29; discussion 529-30. 2002..To review the authors' experience with local excision of early rectal cancers to assess the effectiveness of initial treatment and of salvage surgery...
- Should completely intracorporeal anastomosis be considered in obese patients who undergo laparoscopic colectomy for benign or malignant disease of the colon?Ioannis Raftopoulos
Division of Minimally Invasive, Bariatric and General Surgery, UPMC Shadyside and Magee Women s Hospitals, University of Pittsburgh, PA, USA
Surgery 140:675-82; discussion 682-3. 2006..The outcome of laparoscopic colectomy with completely intracorporeal anastomosis (LCIA) in obese and nonobese patients is assessed...