ROY DRAKE BLOEBAUM

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. pmc Does using autograft bone chips achieve consistent bone ingrowth in primary TKA?
    Roy D Bloebaum
    Bone and Joint Research Laboratory 151F, Department of Veterans Affairs Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT 84148, USA
    Clin Orthop Relat Res 470:1869-78. 2012
  2. ncbi request reprint Loading conditions and cortical bone construction of an artiodactyl calcaneus
    S C Su
    Bone and Joint Research Laboratory, Department of Veteran s Affairs Medical Center, Salt Lake City, UT 84148, USA City, UT 84112, USA
    J Exp Biol 202:3239-54. 1999
  3. ncbi request reprint Relationship between bone ingrowth, mineral apposition rate, and osteoblast activity
    R D Bloebaum
    Bone and Joint Research Lab, Research Service, VA SLC Health Care System, 500 Foothill Blvd, Salt Lake City, Utah 84148, USA
    J Biomed Mater Res A 81:505-14. 2007
  4. ncbi request reprint Mineral content changes in bone associated with damage induced by the electron beam
    Roy D Bloebaum
    Bone and Joint Research Laboratory, Department of Veterans Affairs Medical Center, Salt Lake City Health Care System, Salt Lake City, UT 84148 9998, USA
    Scanning 27:240-8. 2005
  5. ncbi request reprint Age-related mineralization heterogeneity changes in trabecular bone of the proximal femur
    Roy D Bloebaum
    Bone and Joint Research Laboratory 151F, Veterans Affairs Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT 84148, USA
    Anat Rec A Discov Mol Cell Evol Biol 281:1296-302. 2004
  6. ncbi request reprint Remodeling capacity of calcified fibrocartilage of the hip
    Roy D Bloebaum
    Bone and Joint Research Laboratory, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, UT 84048
    Anat Rec A Discov Mol Cell Evol Biol 279:736-9. 2004
  7. ncbi request reprint Measurement of femoral anteversion by biplane radiography and computed tomography imaging: comparison with an anatomic reference
    Tony Y Kuo
    Bone and Joint Research Laboratory, Department of Veterans Affairs Salt Lake City Health Care System, Utah 84148, USA
    Invest Radiol 38:221-9. 2003
  8. ncbi request reprint Cement lines of secondary osteons in human bone are not mineral-deficient: new data in a historical perspective
    John G Skedros
    Bone and Joint Research Laboratory, Department of Veterans Affairs Medical Center, Salt Lake City, Utah, USA
    Anat Rec A Discov Mol Cell Evol Biol 286:781-803. 2005
  9. pmc Pig dorsum model for examining impaired wound healing at the skin-implant interface of percutaneous devices
    Brian Mueller Holt
    Bone and Joint Research Laboratory, DVA SLC HCS, 500 Foothill Drive, 151F, Salt Lake City, UT 84148, USA
    J Mater Sci Mater Med 24:2181-93. 2013
  10. doi request reprint Characterization of bacterial isolates collected from a sheep model of osseointegration
    Dustin L Williams
    Associated Regional and University Pathologists ARUP Laboratories, ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Curr Microbiol 61:574-83. 2010

Collaborators

Detail Information

Publications33

  1. pmc Does using autograft bone chips achieve consistent bone ingrowth in primary TKA?
    Roy D Bloebaum
    Bone and Joint Research Laboratory 151F, Department of Veterans Affairs Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT 84148, USA
    Clin Orthop Relat Res 470:1869-78. 2012
    ..Factors predicting durable fixation are not clearly understood, but we presumed bone ingrowth could be enhanced by the quantity of host bone and application of autograft bone chips...
  2. ncbi request reprint Loading conditions and cortical bone construction of an artiodactyl calcaneus
    S C Su
    Bone and Joint Research Laboratory, Department of Veteran s Affairs Medical Center, Salt Lake City, UT 84148, USA City, UT 84112, USA
    J Exp Biol 202:3239-54. 1999
    ..Variations in osteon and/or collagen fiber orientation may correlate more strongly with principal strain direction...
  3. ncbi request reprint Relationship between bone ingrowth, mineral apposition rate, and osteoblast activity
    R D Bloebaum
    Bone and Joint Research Lab, Research Service, VA SLC Health Care System, 500 Foothill Blvd, Salt Lake City, Utah 84148, USA
    J Biomed Mater Res A 81:505-14. 2007
    ....
  4. ncbi request reprint Mineral content changes in bone associated with damage induced by the electron beam
    Roy D Bloebaum
    Bone and Joint Research Laboratory, Department of Veterans Affairs Medical Center, Salt Lake City Health Care System, Salt Lake City, UT 84148 9998, USA
    Scanning 27:240-8. 2005
    ..When point mode is used to analyze minute regions, adjustments in accelerating voltages and probe current may be required to minimize damage...
  5. ncbi request reprint Age-related mineralization heterogeneity changes in trabecular bone of the proximal femur
    Roy D Bloebaum
    Bone and Joint Research Laboratory 151F, Veterans Affairs Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT 84148, USA
    Anat Rec A Discov Mol Cell Evol Biol 281:1296-302. 2004
    ..Future studies should examine a longer population base to confirm this observation...
  6. ncbi request reprint Remodeling capacity of calcified fibrocartilage of the hip
    Roy D Bloebaum
    Bone and Joint Research Laboratory, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, UT 84048
    Anat Rec A Discov Mol Cell Evol Biol 279:736-9. 2004
    ..The results of this investigation demonstrate that while the underlying cortical bone was actively remodeling, the calcified fibrocartilage appeared to have no remodeling capacity similar to that of cortical bone...
  7. ncbi request reprint Measurement of femoral anteversion by biplane radiography and computed tomography imaging: comparison with an anatomic reference
    Tony Y Kuo
    Bone and Joint Research Laboratory, Department of Veterans Affairs Salt Lake City Health Care System, Utah 84148, USA
    Invest Radiol 38:221-9. 2003
    ..The ability of biplane radiography and standard computed tomography (CT) imaging techniques to measure accurately the human femoral anteversion was evaluated and compared with an anatomic reference: the osteometric method...
  8. ncbi request reprint Cement lines of secondary osteons in human bone are not mineral-deficient: new data in a historical perspective
    John G Skedros
    Bone and Joint Research Laboratory, Department of Veterans Affairs Medical Center, Salt Lake City, Utah, USA
    Anat Rec A Discov Mol Cell Evol Biol 286:781-803. 2005
    ..These data reject the hypothesis that cement lines of secondary osteons are poorly mineralized...
  9. pmc Pig dorsum model for examining impaired wound healing at the skin-implant interface of percutaneous devices
    Brian Mueller Holt
    Bone and Joint Research Laboratory, DVA SLC HCS, 500 Foothill Drive, 151F, Salt Lake City, UT 84148, USA
    J Mater Sci Mater Med 24:2181-93. 2013
    ....
  10. doi request reprint Characterization of bacterial isolates collected from a sheep model of osseointegration
    Dustin L Williams
    Associated Regional and University Pathologists ARUP Laboratories, ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Curr Microbiol 61:574-83. 2010
    ..Two factors are believed to have contributed to this outcome: the delivery of CSA-13 and the lack of a skin seal at the skin/implant interface, which would create a biological barrier to infection...
  11. ncbi request reprint Effectiveness of resonance frequency in predicting orthopedic implant strength and stability in an in vitro osseointegration model
    Brad M Isaacson
    Bone and Joint Research Laboratory 151F, VA Salt Lake City Health Care System, Salt Lake City, UT 84148, USA
    J Rehabil Res Dev 46:1109-20. 2009
    ..The force required for implant displacement also correlated to the distance from the point of fixation to the transducer at the proximal end of the implant (point of resonance frequency monitoring)...
  12. ncbi request reprint Spinal cage retrieval and assessment of biologic response
    Darrel S Brodke
    Department of Orthopedics, School of Medicine 3B165, University of Utah, 50 North Medical Drive, Salt Lake City, UT 84132, U S A
    J Spinal Disord Tech 15:206-12. 2002
    ..An implant retrieval analysis program similar to the one discussed in the presented case study will enable an accurate assessment of outcomes of these commonly used implants and will guide future development...
  13. doi request reprint Assessing peri-implant tissue infection prevention in a percutaneous model
    Emily L Perry
    Bone and Joint Research Laboratory, Veterans Affairs Health Care System, Salt Lake City, Utah, USA
    J Biomed Mater Res B Appl Biomater 92:397-408. 2010
    ..The purpose of this investigation was to determine if a broad spectrum antimicrobial, Ceragenin (CSA-13) could prevent pin track infections in a percutaneous tibial pin site in a sheep model...
  14. ncbi request reprint Experimental confirmation of the sheep model for studying the role of calcified fibrocartilage in hip fractures and tendon attachments
    Jill E Shea
    Bone and Joint Research Laboratory, VA Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT 84148, USA
    Anat Rec 266:177-83. 2002
    ..This suggests that the tendon insertions of the sheep are a better model than the tendon insertions of the rat for the investigation of calcified fibrocartilage in elderly hip fractures...
  15. ncbi request reprint Biological effects of calcium sulfate as a bone graft substitute in ovine metaphyseal defects
    Christopher L Peters
    Department of Orthopaedics, University of Utah Orthopaedic Center, 590 Wakara Way, Salt Lake City, Utah 84108, USA
    J Biomed Mater Res A 76:456-62. 2006
    ..Calcium sulfate appears to be a useful biocompatible bone graft substitute that yields results similar to autograft bone in sheep metaphyseal defects...
  16. ncbi request reprint Microvascularization of the hypermineralized calcified fibrocartilage and cortical bone in the sheep proximal femur
    Jill E Shea
    Bone and Joint Research Laboratory, VA Salt Lake City Health Care System, Salt Lake City, Utah 84184, USA
    Anat Rec 268:365-70. 2002
    ..Therefore future research should examine the role of the vascularity to the proximal femur in the mechanisms of numerous pathological conditions, such as avascular necrosis, osteopenia, and hip fractures...
  17. doi request reprint Immediate post-implantation skin immobilization decreases skin regression around percutaneous osseointegrated prosthetic implant systems
    Brian Mueller Holt
    Bone and Joint Research Laboratory, DVA SLC HCS, Salt Lake City, Utah 84148 Department of Orthopaedics, University of Utah, Salt Lake City, Utah 84108, USA
    J Biomed Mater Res A 101:2075-82. 2013
    ..The skin adaptations reported here will aid in informing the design and optimization of future percutaneous, OI devices intended for the treatment of upper- and lower-extremity amputees...
  18. ncbi request reprint Determining the degree of cortical bone asymmetry in bilateral, nonpathological, human femur pairs
    Teri G Rosenbaum
    Bone and Joint Research Lab 151F, SLC VA Health Care System, 500 Foothill Blvd, Salt Lake City, UT 84148, USA
    J Biomed Mater Res A 76:450-5. 2006
    ..6%. In conclusion, the data supports attributing cortical bone shape differences between implanted and contralateral nonimplanted femurs in levels 2-8 to the presence of the implant when the significant differences are greater than 6.6%...
  19. pmc Developing a quantitative measurement system for assessing heterotopic ossification and monitoring the bioelectric metrics from electrically induced osseointegration in the residual limb of service members
    Brad M Isaacson
    Department of Veterans Affairs, Salt Lake City, UT 84148, USA
    Ann Biomed Eng 38:2968-78. 2010
    ..041, r = -0.622). This study demonstrates that the volume of HO and age may affect the voltage threshold necessary to improve current osseointegration procedures...
  20. ncbi request reprint The relationship between femoral periprosthetic cortical bone geometry and porosity after total hip arthroplasty
    Teri G Rosenbaum Chou
    Bone and Joint Research Lab 151F, SLC VA Health Care System, 500 Foothill Blvd, Salt Lake City, Utah 84148, USA
    J Biomed Mater Res A 87:107-15. 2008
    ..In conclusion, the porosity increases in the implanted femurs may have regionally reduced cortical bone strength. The locations of higher porosity did not appear related to the cortical bone geometry...
  21. doi request reprint Evaluating antimicrobials and implant materials for infection prevention around transcutaneous osseointegrated implants in a rabbit model
    Teri G Rosenbaum Chou
    Bone and Joint Research Laboratory 151F, Department of Veterans Affairs Health Care System, Salt Lake City, Utah 84148 9998, USA
    J Biomed Mater Res A 92:942-52. 2010
    ..Porous tantalum will not likely prevent pin tract infection without additional methods of soft tissue immobilization around the implant site...
  22. ncbi request reprint Does celecoxib have an adverse effect on bone remodeling and ingrowth in humans?
    Aaron A Hofmann
    Department of Orthopaedics, University of Utah School of Medicine, Salt Lake City, UT, USA
    Clin Orthop Relat Res 452:200-4. 2006
    ..97 microm per day) and the tantalum (1.15 microm per day) plugs at 12 weeks as was bone ingrowth (886 microm versus 632 microm, respectively). Celecoxib does not seem to inhibit bone ingrowth or bone formation...
  23. ncbi request reprint Dual-energy x-ray absorptiometry measurement and accuracy of bone mineral after unilateral total hip arthroplasty
    Roy D Bloebaum
    Bone and Joint Research Laboratory, Salt Lake City Veterans Administration Health Care System, Salt Lake City, UT, USA
    J Arthroplasty 21:612-22. 2006
    ..Dual-energy x-ray absorptiometry failed to show an acceptable level of accuracy compared with ash data (r = 0.56; P = .002). It did show relative patterns of bone loss. Bone loss was consistent with implant-induced stress shielding...
  24. ncbi request reprint A comparative staining technique to detect mineral oil contaminants from orthopedic implants
    Bettina M Willie
    Bone and Joint Research Lab 151F, SLC VA Health Care System, 500 Foothill Boulevard, Salt Lake City, Utah 84148, USA
    J Biomed Mater Res B Appl Biomater 70:130-8. 2004
    ..Histological analysis of sheep tissue and saline-injected rabbit tissue showed no evidence of mineral oil or adverse tissue response...
  25. ncbi request reprint Are uniform regional safety factors an objective of adaptive modeling/remodeling in cortical bone?
    John G Skedros
    Utah Bone and Joint Center, Salt Lake City, UT 84115, USA
    J Exp Biol 206:2431-9. 2003
    ..Contrary to the hypothesis of uniform safety factors, the MC3 has a broad range of tension (caudo-medial, 4.0; cranio-lateral, 37.7) and compression (caudo-medial, 5.7; cranio-lateral, 68.9) safety factors...
  26. ncbi request reprint Bone viability determination in human cancellous bone from patients undergoing revision hip arthroplasty
    Roy D Bloebaum
    Department of Veterans Affairs, Salt Lake City Health Care System, Utah 84148, USA
    J Arthroplasty 19:745-50. 2004
    ..Significant improvement was observed in postoperative Harris Hip Scores when compared with preoperative Harris Hip Scores...
  27. ncbi request reprint Oxidative degradation in highly cross-linked and conventional polyethylene after 2 years of real-time shelf aging
    Bettina M Willie
    Bone and Joint Research Lab 151F, SLC VA Health Care System, Salt Lake City, UT 84148, USA
    Biomaterials 27:2275-84. 2006
    ..It is likely that current manufacturing and packaging technologies have limited the previous clinical concerns related to oxidative degradation during shelf aging of highly cross-linked and conventional PE components...
  28. ncbi request reprint Ambulatory activities maintain cortical bone after total hip arthroplasty
    Teri G Rosenbaum
    Bone and Joint Research Lab 151F, SLC VA Health Care System, 500 Foothill Boulevard, Salt Lake City, UT 84148, USA
    Clin Orthop Relat Res 450:129-37. 2006
    ..Principal axis location did not change. Bone loss was more likely to occur uniformly than to change cortical bone distribution. Bone loss was minimized in patients with higher activity levels...
  29. ncbi request reprint Regional differences in cortical bone organization and microdamage prevalence in Rocky Mountain mule deer
    John G Skedros
    Department of Veterans Affairs Medical Center, Salt Lake City, Utah, USA
    Anat Rec A Discov Mol Cell Evol Biol 274:837-50. 2003
    ....
  30. ncbi request reprint Determining relevance of a weight-bearing ovine model for bone ingrowth assessment
    Bettina M Willie
    Bone and Joint Research Lab 151F, Salt Lake City Veterans Affairs Health Care System, and Department of Bioengineering, University of Utah, 84148, USA
    J Biomed Mater Res A 69:567-76. 2004
    ..The results of this study appear to validate the ovine model for use in understanding skeletal attachment of porous-coated implants to cancellous bone in humans...
  31. ncbi request reprint Quantifying the effect of resin type and sterilization method on the degradation of ultrahigh molecular weight polyethylene after 4 years of real-time shelf aging
    Bettina M Willie
    Bone and Joint Research Lab 151F, Salt Lake City Veterans Affairs Health Care System, and Department of Bioengineering, University of Utah, USA
    J Biomed Mater Res A 69:477-89. 2004
    ..079) when examining the influence of sterilization method. The data supported that after 4 years of real-time shelf aging, the type of sterilization method had a larger influence on PE degradation than resin type...
  32. ncbi request reprint A comparison of the microarchitectural bone adaptations of the concave and convex thoracic spinal facets in idiopathic scoliosis
    Kevin G Shea
    St Luke s Children s Hospital, Boise, Idaho 83702, USA
    J Bone Joint Surg Am 86:1000-6. 2004
    ..The purpose of this study was to analyze the facets in patients with scoliosis to determine whether there are differences in the bone microarchitecture of contralateral facets at the same anatomic level...
  33. pmc An assessment of the biological fixation of a retrieved Mayo femoral component
    Russell D Meldrum
    Indiana University, School of Medicine, Department of Orthopedics, 541 Clinical Drive, Room 600, Indianapolis, IN 46202 5111, USA
    Iowa Orthop J 23:103-7. 2003
    ..These results are similar to percentages of ingrowth seen with more conventional, anatomic design prostheses...

Research Grants2

  1. Prevention of Biofilm Related Infections Using a Novel, Broad Spectrum Antimicrob
    Roy Bloebaum; Fiscal Year: 2009
    ..We hope this will give civilian and military patients a more sure way of avoiding infection in grossly contaminated wounds. ..
  2. Prevention of Biofilm Related Infections Using a Novel, Broad Spectrum Antimicrob
    ROY DRAKE BLOEBAUM; Fiscal Year: 2010
    ..We hope this will give civilian and military patients a more sure way of avoiding infection in grossly contaminated wounds. ..