William A Blattner

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi request reprint Rapid clearance of virus after acute HIV-1 infection: correlates of risk of AIDS
    William A Blattner
    Institute of Human Virology, University of Maryland, Baltimore, Maryland, USA
    J Infect Dis 189:1793-801. 2004
  2. pmc HIV-1 epidemic in the Caribbean is dominated by subtype B
    Yuka Nadai
    Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America
    PLoS ONE 4:e4814. 2009
  3. pmc Elevated hypermutation levels in HIV-1 natural viral suppressors
    Lindsay M Eyzaguirre
    Institute of Human Virology, University of Maryland School of Medicine, Baltimore, United States 725 West Lombard Street Baltimore, MD 21201, USA
    Virology 443:306-12. 2013
  4. pmc Protocol for nearly full-length sequencing of HIV-1 RNA from plasma
    Yuka Nadai
    Department of Epidemiology, Institute of Human Virology, University of Maryland, Baltimore, Maryland, USA
    PLoS ONE 3:e1420. 2008
  5. ncbi request reprint Improved classification of recent HIV-1 infection by employing a two-stage sensitive/less-sensitive test strategy
    Niel T Constantine
    Department of Pathology, University of Maryland, School of Medicine, Baltimore, Maryland 21201, USA
    J Acquir Immune Defic Syndr 32:94-103. 2003
  6. pmc Clinical features and preliminary studies of virological correlates of neurocognitive impairment among HIV-infected individuals in Nigeria
    Walter Royal
    Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA
    J Neurovirol 18:191-9. 2012
  7. ncbi request reprint Risk factors for in utero and intrapartum transmission of HIV
    Laurence S Magder
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 38:87-95. 2005
  8. ncbi request reprint Neurocognitive impairment associated with predominantly early stage HIV infection in Abuja, Nigeria
    Christopher Akolo
    The Institute of Human Virology at the University of Maryland School of Medicine, Baltimore, MD, USA
    J Neurovirol 20:380-7. 2014
  9. ncbi request reprint A cohort study of health effects of human T-cell lymphotropic virus type I infection in Jamaican children
    Elizabeth M Maloney
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, Bethesda, Maryland, USA
    Pediatrics 112:e136-42. 2003
  10. doi request reprint Tenofovir-based regimens associated with less drug resistance in HIV-1-infected Nigerians failing first-line antiretroviral therapy
    Mary Ann A Etiebet
    Institute of Human Virology, University of Maryland School of Medicine, MD, USA
    AIDS 27:553-61. 2013

Research Grants

  1. HIV-1 Incidence and Genetic Diversity in the Caribbean
    William Blattner; Fiscal Year: 2004
  2. Impact of Alcohol Consumption on HIV/AIDS in Women
    William Blattner; Fiscal Year: 2005
  3. Institute of Human Virology Clinical Trials Unit
    William Blattner; Fiscal Year: 2007
  4. COALITION FOR HIV VACCINE DEVELOPMENT
    William Blattner; Fiscal Year: 2006

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Rapid clearance of virus after acute HIV-1 infection: correlates of risk of AIDS
    William A Blattner
    Institute of Human Virology, University of Maryland, Baltimore, Maryland, USA
    J Infect Dis 189:1793-801. 2004
    ..Our objective was to define early virologic and immunologic determinants of human immunodeficiency virus (HIV) type 1 disease progression among 22 case subjects with acute infection from the Trinidad Seroconvertor Cohort...
  2. pmc HIV-1 epidemic in the Caribbean is dominated by subtype B
    Yuka Nadai
    Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America
    PLoS ONE 4:e4814. 2009
    ..To expand our knowledge of this, nearly full genome amplification, sequencing and analysis was conducted...
  3. pmc Elevated hypermutation levels in HIV-1 natural viral suppressors
    Lindsay M Eyzaguirre
    Institute of Human Virology, University of Maryland School of Medicine, Baltimore, United States 725 West Lombard Street Baltimore, MD 21201, USA
    Virology 443:306-12. 2013
    ..043). Our data suggests that inactivation of the virus through the APOBEC3G system may contribute to the NVS phenotype...
  4. pmc Protocol for nearly full-length sequencing of HIV-1 RNA from plasma
    Yuka Nadai
    Department of Epidemiology, Institute of Human Virology, University of Maryland, Baltimore, Maryland, USA
    PLoS ONE 3:e1420. 2008
    ..This protocol provides a useful tool for molecular analysis to understand the HIV epidemic and pathogenesis, as well as diagnosis, therapy and future vaccine strategies...
  5. ncbi request reprint Improved classification of recent HIV-1 infection by employing a two-stage sensitive/less-sensitive test strategy
    Niel T Constantine
    Department of Pathology, University of Maryland, School of Medicine, Baltimore, Maryland 21201, USA
    J Acquir Immune Defic Syndr 32:94-103. 2003
    ....
  6. pmc Clinical features and preliminary studies of virological correlates of neurocognitive impairment among HIV-infected individuals in Nigeria
    Walter Royal
    Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA
    J Neurovirol 18:191-9. 2012
    ....
  7. ncbi request reprint Risk factors for in utero and intrapartum transmission of HIV
    Laurence S Magder
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 38:87-95. 2005
    ..To identify predictors of in utero and intrapartum HIV-1 transmission in infants born in the Women and Infants Transmission Study between 1990 and 2000...
  8. ncbi request reprint Neurocognitive impairment associated with predominantly early stage HIV infection in Abuja, Nigeria
    Christopher Akolo
    The Institute of Human Virology at the University of Maryland School of Medicine, Baltimore, MD, USA
    J Neurovirol 20:380-7. 2014
    ..Confirmation of these findings awaits analyses using data from a larger number of control subjects. ..
  9. ncbi request reprint A cohort study of health effects of human T-cell lymphotropic virus type I infection in Jamaican children
    Elizabeth M Maloney
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, Bethesda, Maryland, USA
    Pediatrics 112:e136-42. 2003
    ..Although HTLV-I is known to be associated with infective dermatitis in childhood, other HTLV-I-associated morbidity in children has not been well studied. We sought to determine the HTLV-I-associated health effects in Jamaican children...
  10. doi request reprint Tenofovir-based regimens associated with less drug resistance in HIV-1-infected Nigerians failing first-line antiretroviral therapy
    Mary Ann A Etiebet
    Institute of Human Virology, University of Maryland School of Medicine, MD, USA
    AIDS 27:553-61. 2013
    ..We retrospectively conducted genotypic analysis on archived samples from Nigerian patients who received targeted viral load testing to confirm treatment failure and report their drug resistance mutation patterns...
  11. ncbi request reprint Development of vaccination strategies that elicit broadly neutralizing antibodies against human immunodeficiency virus type 1 in both the mucosal and systemic immune compartments
    David M Hone
    Divisions of Basic Science and Vaccine Research, Institute of Human Virology, University of Maryland Biotechnology Institute, Baltimore, Maryland 21201, USA
    J Hum Virol 5:17-23. 2002
    ..This paper reviews recent advances made by the authors toward the development of an HIV-1 vaccine that elicits such antibodies in both the mucosal and systemic immune compartments...
  12. pmc Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
    Brandon F Keele
    Departments of Medicine and Microbiology, University of Alabama at Birmingham, Birmingham, AL 35223, USA
    Proc Natl Acad Sci U S A 105:7552-7. 2008
    ....
  13. ncbi request reprint Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers
    Paul A Goepfert
    University of Alabama at Birmingham, 908 20th Street South, CCB 328, Birmingham, AL 35294, USA
    Vaccine 25:510-8. 2007
    ..Use of the recombinant proteins NefTat and gp120(W61D) formulated with the AS02A adjuvant system was previously shown to protect against AIDS in a rhesus macaque SHIV animal model system...
  14. ncbi request reprint High-dose recombinant Canarypox vaccine expressing HIV-1 protein, in seronegative human subjects
    Paul A Goepfert
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 2050, USA
    J Infect Dis 192:1249-59. 2005
    ..0) TCID50 (60 participants) than when given at the regular dose, 10(7.26) TCID50 (40 participants); as a control, a placebo vaccine preparation also was administered (10 participants)...
  15. pmc Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial
    Nina D Russell
    Program in Infectious Diseases, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    J Acquir Immune Defic Syndr 44:203-12. 2007
    ..We conducted a phase 2 trial to determine if a canarypox vaccine candidate (vCP1452) administered with rgp120 subunit protein would "qualify" for a trial to define a correlate of efficacy...
  16. ncbi request reprint Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers
    Miriam C Poirier
    Carcinogen DNA Interactions Section, National Cancer Institute, National Institutes of Health, Building 37, Room 4032, 37 Convent Drive, Bethesda, MD 20892 4255, USA
    J Acquir Immune Defic Syndr 33:175-83. 2003
    ..The study shows that children of HIV+ mothers are at risk for mitochondrial damage that is further increased in infants of mothers receiving AZT during pregnancy...

Research Grants8

  1. HIV-1 Incidence and Genetic Diversity in the Caribbean
    William Blattner; Fiscal Year: 2004
    ....
  2. Impact of Alcohol Consumption on HIV/AIDS in Women
    William Blattner; Fiscal Year: 2005
    ..to-child transmission of HIV. ..
  3. Institute of Human Virology Clinical Trials Unit
    William Blattner; Fiscal Year: 2007
    ..Results of this clinical research impact the public health by advancing HIV treatment standards, developing a vaccine, and learning more effective approaches to HIV prevention. ADMINISTRATIVE COMPONENT: ..
  4. COALITION FOR HIV VACCINE DEVELOPMENT
    William Blattner; Fiscal Year: 2006
    ..abstract_text> ..