William A Blattner
Affiliation: University of Maryland
- Rapid clearance of virus after acute HIV-1 infection: correlates of risk of AIDSWilliam A Blattner
Institute of Human Virology, University of Maryland, Baltimore, Maryland, USA
J Infect Dis 189:1793-801. 2004..Our objective was to define early virologic and immunologic determinants of human immunodeficiency virus (HIV) type 1 disease progression among 22 case subjects with acute infection from the Trinidad Seroconvertor Cohort...
- HIV-1 epidemic in the Caribbean is dominated by subtype BYuka Nadai
Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America
PLoS ONE 4:e4814. 2009..To expand our knowledge of this, nearly full genome amplification, sequencing and analysis was conducted...
- Elevated hypermutation levels in HIV-1 natural viral suppressorsLindsay M Eyzaguirre
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, United States 725 West Lombard Street Baltimore, MD 21201, USA
Virology 443:306-12. 2013..043). Our data suggests that inactivation of the virus through the APOBEC3G system may contribute to the NVS phenotype...
- Protocol for nearly full-length sequencing of HIV-1 RNA from plasmaYuka Nadai
Department of Epidemiology, Institute of Human Virology, University of Maryland, Baltimore, Maryland, USA
PLoS ONE 3:e1420. 2008..This protocol provides a useful tool for molecular analysis to understand the HIV epidemic and pathogenesis, as well as diagnosis, therapy and future vaccine strategies...
- Improved classification of recent HIV-1 infection by employing a two-stage sensitive/less-sensitive test strategyNiel T Constantine
Department of Pathology, University of Maryland, School of Medicine, Baltimore, Maryland 21201, USA
J Acquir Immune Defic Syndr 32:94-103. 2003....
- Clinical features and preliminary studies of virological correlates of neurocognitive impairment among HIV-infected individuals in NigeriaWalter Royal
Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA
J Neurovirol 18:191-9. 2012....
- Risk factors for in utero and intrapartum transmission of HIVLaurence S Magder
Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, MD, USA
J Acquir Immune Defic Syndr 38:87-95. 2005..To identify predictors of in utero and intrapartum HIV-1 transmission in infants born in the Women and Infants Transmission Study between 1990 and 2000...
- Neurocognitive impairment associated with predominantly early stage HIV infection in Abuja, NigeriaChristopher Akolo
The Institute of Human Virology at the University of Maryland School of Medicine, Baltimore, MD, USA
J Neurovirol 20:380-7. 2014..Confirmation of these findings awaits analyses using data from a larger number of control subjects. ..
- A cohort study of health effects of human T-cell lymphotropic virus type I infection in Jamaican childrenElizabeth M Maloney
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, Bethesda, Maryland, USA
Pediatrics 112:e136-42. 2003..Although HTLV-I is known to be associated with infective dermatitis in childhood, other HTLV-I-associated morbidity in children has not been well studied. We sought to determine the HTLV-I-associated health effects in Jamaican children...
- Tenofovir-based regimens associated with less drug resistance in HIV-1-infected Nigerians failing first-line antiretroviral therapyMary Ann A Etiebet
Institute of Human Virology, University of Maryland School of Medicine, MD, USA
AIDS 27:553-61. 2013..We retrospectively conducted genotypic analysis on archived samples from Nigerian patients who received targeted viral load testing to confirm treatment failure and report their drug resistance mutation patterns...
- Development of vaccination strategies that elicit broadly neutralizing antibodies against human immunodeficiency virus type 1 in both the mucosal and systemic immune compartmentsDavid M Hone
Divisions of Basic Science and Vaccine Research, Institute of Human Virology, University of Maryland Biotechnology Institute, Baltimore, Maryland 21201, USA
J Hum Virol 5:17-23. 2002..This paper reviews recent advances made by the authors toward the development of an HIV-1 vaccine that elicits such antibodies in both the mucosal and systemic immune compartments...
- Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infectionBrandon F Keele
Departments of Medicine and Microbiology, University of Alabama at Birmingham, Birmingham, AL 35223, USA
Proc Natl Acad Sci U S A 105:7552-7. 2008....
- Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteersPaul A Goepfert
University of Alabama at Birmingham, 908 20th Street South, CCB 328, Birmingham, AL 35294, USA
Vaccine 25:510-8. 2007..Use of the recombinant proteins NefTat and gp120(W61D) formulated with the AS02A adjuvant system was previously shown to protect against AIDS in a rhesus macaque SHIV animal model system...
- High-dose recombinant Canarypox vaccine expressing HIV-1 protein, in seronegative human subjectsPaul A Goepfert
Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 2050, USA
J Infect Dis 192:1249-59. 2005..0) TCID50 (60 participants) than when given at the regular dose, 10(7.26) TCID50 (40 participants); as a control, a placebo vaccine preparation also was administered (10 participants)...
- Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trialNina D Russell
Program in Infectious Diseases, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
J Acquir Immune Defic Syndr 44:203-12. 2007..We conducted a phase 2 trial to determine if a canarypox vaccine candidate (vCP1452) administered with rgp120 subunit protein would "qualify" for a trial to define a correlate of efficacy...
- Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothersMiriam C Poirier
Carcinogen DNA Interactions Section, National Cancer Institute, National Institutes of Health, Building 37, Room 4032, 37 Convent Drive, Bethesda, MD 20892 4255, USA
J Acquir Immune Defic Syndr 33:175-83. 2003..The study shows that children of HIV+ mothers are at risk for mitochondrial damage that is further increased in infants of mothers receiving AZT during pregnancy...
- HIV-1 Incidence and Genetic Diversity in the CaribbeanWilliam Blattner; Fiscal Year: 2004....
- Impact of Alcohol Consumption on HIV/AIDS in WomenWilliam Blattner; Fiscal Year: 2005..to-child transmission of HIV. ..
- Institute of Human Virology Clinical Trials UnitWilliam Blattner; Fiscal Year: 2007..Results of this clinical research impact the public health by advancing HIV treatment standards, developing a vaccine, and learning more effective approaches to HIV prevention. ADMINISTRATIVE COMPONENT: ..
- COALITION FOR HIV VACCINE DEVELOPMENTWilliam Blattner; Fiscal Year: 2006..abstract_text> ..