Research Topics
| P D BlancSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Higher environmental relative moldiness index values measured in homes of adults with asthma, rhinitis, or both conditionsPaul D Blanc
Department of Medicine, University of California San Francisco, San Francisco, CA, USA
Environ Res 122:98-101. 2013..0001). In this study in Northern California, the homes of adults with asthma had ERMI values consistent with a heavier burden of indoor mold than that measured in other homes from the same region...- A patient on RIPE therapy presenting with recurrent isoniazid-associated pleural effusions: a case reportVanja Varenika
Department of Occupational and Environmental Medicine, University of California, San Francisco, 350 Parnassus Avenue, Room 609, San Francisco, CA 94143 0924, USA
J Med Case Rep 5:558. 2011..abstract:.. 
Occupation and COPD: a brief reviewPaul D Blanc
Department of Medicine, Division of Occupational and Environmental Medicine, University of California, San Francisco, San Francisco, CA 94117, USA
J Asthma 49:2-4. 2012..This review summarizes the scientific literature relevant to occupational risk factors for chronic obstructive pulmonary disease (COPD)...- Matrix metalloproteinase-9 predicts pulmonary status declines in α1-antitrypsin deficiencyTheodore A Omachi
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
Respir Res 12:35. 2011..Matrix metalloproteinase-9 (MMP-9) may be important in the progression of emphysema, but there have been few longitudinal clinical studies of MMP-9 including pulmonary status and COPD exacerbation outcomes... - Body composition and functional limitation in COPDMark D Eisner
Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, USA
Respir Res 8:7. 2007..Low body mass index has been associated with increased mortality in severe COPD. The impact of body composition earlier in the disease remains unclear. We studied the impact of body composition on the risk of functional limitation in COPD... - Alpha-1-antitrypsin deficient man presenting with lung function decline associated with dust exposure: a case reportMoshe Zutler
505 Parnassus Avenue, M1097, San Francisco, CA 94143, USA
J Med Case Reports 5:154. 2011..abstract:.. - An integrated model of environmental factors in adult asthma lung function and disease severity: a cross-sectional studyLaura Trupin
Department of Medicine, University of California San Francisco, San Francisco, CA, USA
Environ Health 9:24. 2010..We sought to evaluate the contribution of combined social and physical environmental exposures to adult asthma lung function and disease severity... - Asthma caused by occupational exposures is common - a systematic analysis of estimates of the population-attributable fractionKjell Toren
Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Goteborg, Sweden
BMC Pulm Med 9:7. 2009..In recent years there has been a growing recognition of the potential importance of asthma induced by work-related exposures.. - Directly measured secondhand smoke exposure and COPD health outcomesMark D Eisner
Department of Medicine, University of California, San Francisco, UCSF Box 0924, San Francisco, CA 94113 0924, USA
BMC Pulm Med 6:12. 2006..Despite the importance of this question, the impact of SHS exposure on COPD health outcomes remains unknown... 
Occupation in chronic obstructive pulmonary disease and chronic bronchitis: an updateP D Blanc
Division of Occupational and Environmental Medicine, University of California San Francisco, San Francisco, California, USA
Int J Tuberc Lung Dis 11:251-7. 2007..This review supports previous analyses concluding that there is a causal association between work-related exposures and COPD...- Further exploration of the links between occupational exposure and chronic obstructive pulmonary diseasePaul D Blanc
Division of Occupational and Environmental Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA 94143 0924, USA
J Occup Environ Med 51:804-10. 2009..To examine occupational risk for Chronic Obstructive Pulmonary Disease (COPD)... - Occupational exposures and COPD: an ecological analysis of international dataP D Blanc
Division of Occupational and Environmental Medicine, University of California San Francisco, 350 Parnassus Ave, Suite 609, San Francisco, CA 94117, USA
Eur Respir J 33:298-304. 2009.... - Socioeconomic gradients in tiotropium use among adults with COPDPaul D Blanc
Division of Occupational and Environmental Medicine, Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94143 0924, USA
Int J Chron Obstruct Pulmon Dis 3:483-90. 2008..Inequalities in the use of new medications may contribute to health disparities. We analyzed socioeconomic gradients in the use of tiotropium for chronic obstructive pulmonary disease (COPD)... - Area-level socio-economic status and health status among adults with asthma and rhinitisP D Blanc
Dept of Medicine, University of California San Francisco, San Francisco, CA, USA
Eur Respir J 27:85-94. 2006..In conclusion, area-level socio-economic status is linked to some, but not all, of the studied health status measures after taking into account individual-level socio-economic status... - Performance of self-reported occupational exposure compared to a job-exposure matrix approach in asthma and chronic rhinitisP J Quinlan
Division of Occupational and Environmental Medicine, University of California San Francisco, 1001 Potrero Avenue, San Francisco, CA 94110, USA
Occup Environ Med 66:154-60. 2009..Our objective was to characterise the performance of VGDF for repeatability, systematic misclassification, and sensitivity and specificity against exposure likelihood by a job-exposure matrix (JEM)... - Negative life events and quality of life in adults with asthmaC Archea
Department of Medicine, University of California San Francisco, 350 Parnassus Avenue, Suite 609, San Francisco, CA 94117, USA
Thorax 62:139-46. 2007..Stress, quantified by negative life events, may be linked to quality of life in asthma through multiple pathways, including increase in disease severity and adverse effects on socioeconomic status (SES)... - The association between occupational factors and adverse health outcomes in chronic obstructive pulmonary diseaseP D Blanc
Division of Occupational and Environmental Medicine, University of California San Francisco, 350 Parnassus Avenue, Suite 609, San Francisco, CA 94117, USA
Occup Environ Med 61:661-7. 2004..Despite recognition that occupational exposures may make a substantive contribution to the aetiology of COPD, little is known about the potential role of work related factors in COPD related health outcomes... - Measurement of environmental tobacco smoke exposure among adults with asthmaM D Eisner
Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, California 94117, USA
Environ Health Perspect 109:809-14. 2001..This instrument could be a valuable tool for studying the effect of ETS exposure on adult asthma health outcomes... - Socioeconomic status, race and COPD health outcomesM D Eisner
Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0111, USA
J Epidemiol Community Health 65:26-34. 2011..Although chronic obstructive pulmonary disease (COPD) is a common cause of death and disability, little is known about the effects of socioeconomic status (SES) and race-ethnicity on health outcomes... - Work dynamics of adults with asthmaE Yelin
Department of Medicine, University of California, San Francisco 94143 0920, USA
Am J Ind Med 35:472-80. 1999..Asthma has been found to be among the most common conditions in the working age population and is among the most common causes of work limitation, but we could find no longitudinal studies of employment among persons with this condition... - Risk factors for hospitalization among adults with asthma: the influence of sociodemographic factors and asthma severityM D Eisner
Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, California, USA
Respir Res 2:53-60. 2001..The morbidity and mortality from asthma have markedly increased since the late 1970s. The hospitalization rate, an important marker of asthma severity, remains substantial... - Alternative therapies among adults with a reported diagnosis of asthma or rhinosinusitis : data from a population-based surveyP D Blanc
Division of Occupational and Environmental Medicine, University of California San Francisco, San Francisco, CA 94143 0924, USA
Chest 120:1461-7. 2001..Alternative treatments could have important impacts on health status among those individuals with these conditions, but specific prevalence data for these treatments are limited... - Asthma and smoking status in a population-based study of California adultsM D Eisner
Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco 94117, USA
Public Health Rep 116:148-57. 2001..The authors sought to determine whether adult asthmatics are less likely to smoke cigarettes than members of the general population... - The work impact of asthma and rhinitis: findings from a population-based surveyP D Blanc
Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, San Francisco, CA 94143 0924, USA
J Clin Epidemiol 54:610-8. 2001..The economic impact of asthma and rhinitis and related conditions may be under-appreciated... - The occupational burden of chronic obstructive pulmonary diseaseL Trupin
Division of Rheumatology, University of California, San Francisco, CA 94143 0920, USA
Eur Respir J 22:462-9. 2003.... - Predictors of cigarette smoking and smoking cessation among adults with asthmaM D Eisner
University of California, San Francisco, USA
Am J Public Health 90:1307-11. 2000..This study sought to determine the predictors of smoking and time until smoking cessation in a cohort of adults with asthma... - Occupational exposures and the risk of COPD: dusty trades revisitedP D Blanc
Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA 94117, USA
Thorax 64:6-12. 2009..The contribution of occupational exposures to chronic obstructive pulmonary disease (COPD) and, in particular, their potential interaction with cigarette smoking remains underappreciated... - The association between occupation and asthma in general medical practiceP D Blanc
Department of Medicine, University of California at San Francisco, 94143 0924, USA
Chest 115:1259-64. 1999..In general practice settings, the proportion of adult asthma attributable to occupational factors is not known... - Survival following lung transplantation for silicosis and other occupational lung diseasesJ P Singer
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, CA 94143, USA
Occup Med (Lond) 62:134-7. 2012..Information is scant assessing outcomes in lung transplantation (LT) in advanced occupational lung diseases (OLD)... - Comparison of cardiac and pulmonary-specific quality-of-life measures in pulmonary arterial hypertensionH Chen
Dept of Medicine, University of California, San Francisco, CA 94143 0924, USA
Eur Respir J 38:608-16. 2011..In conclusion, both cardiac-specific and respiratory-specific measures appropriately assess HRQoL in most patients with PAH. Overall, the LHFQ demonstrates stronger performance characteristics than the AQ20... - A thematic analysis of quality of life in lung transplant: the existing evidence and implications for future directionsJ P Singer
Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, University of California, San Francisco, CA, USA
Am J Transplant 13:839-50. 2013..Opportunity for future study lies in validating existing and potential novel HRQL instruments and further elucidating the determinants of HRQL through longitudinal multidimensional investigation... - Beta agonists, inhaled steroids, and the risk of intensive care unit admission for asthmaM D Eisner
Cardiovascular Research Institute, Division of Research Northern California Kaiser Permanente, University of California, San Francisco, USA
Eur Respir J 17:233-40. 2001..This suggests that ICS prescription to adults with moderate-to-severe asthma could reduce the risk of life-threatening exacerbation... - Functional recovery following musculoskeletal injury in hospital workersM Gillen
University of California, San Francisco, CA 94143 0608, USA
Occup Med (Lond) 60:532-9. 2010..Hospital workers are at high risk of work-related musculoskeletal disorders (WRMSDs), but outcomes following such injuries have not been well studied longitudinally... - Gas stove use and respiratory health among adults with asthma in NHANES IIIM D Eisner
Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, CA 94117, USA
Occup Environ Med 60:759-64. 2003..Adults with asthma may be susceptible to the effects of gas stove exposure because of their underlying airway hyperresponsiveness, but this association has been difficult to establish... - Exposure to indoor combustion and adult asthma outcomes: environmental tobacco smoke, gas stoves, and woodsmokeM D Eisner
Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, 94117, USA
Thorax 57:973-8. 2002..Despite widespread exposure to environmental tobacco smoke (ETS), gas stoves, and woodsmoke, the impact of these exposures on adult asthma has not been well characterised... - The impact of pretransplant mechanical ventilation on short- and long-term survival after lung transplantationJ P Singer
Division of Pulmonary, Critical Care, Allergy and Sleep, Department of Medicine, University of California, San Francisco, USA
Am J Transplant 11:2197-204. 2011..Notably, the increased risk of death appears to be strongest the early posttransplant period and limited to certain pretransplant diagnoses... - Health and socioeconomic impact of work-related asthmaO Vandenplas
Service de Pneumologie, Cliniques de Mont Godinne, Universite Catholique de Louvain, Yvoir, Belgium
Eur Respir J 22:689-97. 2003..clinician's role in reducing the respiratory health consequences of work-related asthma? 6) to what extent do existing compensation and other social insurance schemes successfully address occupational asthma and work-aggravated asthma?.. - TENOR risk score predicts healthcare in adults with severe or difficult-to-treat asthmaM K Miller
Genentech, Inc, 1 DNA Way, MS 214B, South San Francisco, CA 94044, USA
Eur Respir J 28:1145-55. 2006..77). The risk score derived is a clinically useful tool for assessing the likelihood of asthma-related hospitalisation or emergency department visits in adults with severe and difficult-to-treat asthma... - Why quality of life should matter to occupational health researchersP D Blanc
Occup Environ Med 61:571. 2004 - Epidemiology and costs of COPDP D Blanc
Eur Respir J 28:1290. 2006
Research Grants
- Physical and Social Environmental Factors in Adult Asthma OutcomesPaul Blanc; Fiscal Year: 2009..The proposed project builds upon our success in the current R01 by testing more specific pathways in the context of our accumulated experience to date. ..
- Physical and Social Environmental Factors in Adult Asthma OutcomesPaul Blanc; Fiscal Year: 2007..The proposed project builds upon our success in the current R01 by testing more specific pathways in the context of our accumulated experience to date. ..
- Adult Asthma: Biology, Society and EnvironmentPaul Blanc; Fiscal Year: 2005..05 level for dichotomous outcomes. This project addresses a major research need and can be a basis for the development of public policies to address environmentally related and other health disparities in adult asthma. ..
- OCCUPATIONAL HEALTH GRADIENTS IN HOSPITAL WORKERS: THEPaul Blanc; Fiscal Year: 2004..The study team will also work with a labor-management team to develop possible interventions for the problems that are identified by this study. ..
- ASSESSING THE OCCUPATION BURDEN IN COPDPaul Blanc; Fiscal Year: 2002..5 percent. In the longitudinal study component, we should be able to detect a RR>2.1 for selected occupational risk factors as predictors of outcomes occurring in at least 10 percent of the group. ..
- Physical and Social Environmental Factors in Adult Asthma OutcomesPaul D Blanc; Fiscal Year: 2010..The proposed project builds upon our success in the current R01 by testing more specific pathways in the context of our accumulated experience to date. ..