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Genomes and Genes | Dale E BjorlingSummaryAffiliation: University of Wisconsin Country: USA Publications
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Publications
Models of inflammation of the lower urinary tractDale E Bjorling
Department of Surgical Sciences, University of Wisconsin Madison, Madison, WI, USA
Neurourol Urodyn 30:673-82. 2011..Comparative and translational studies are required if the full potential of findings obtained with animal models to improve prevention and treatment of lower urinary tract inflammation in people is to be realized...
Lidocaine prevents referred hyperalgesia associated with cystitisSimone D Guerios
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin, USA
Neurourol Urodyn 28:455-60. 2009..This study was performed to determine whether intrathecal or intravesical administration of lidocaine prior, or subsequent, to induction of chemical cystitis in rats would block referred mechanical hyperalgesia...
Blockade of NGF and trk receptors inhibits increased peripheral mechanical sensitivity accompanying cystitis in ratsSimone D Guerios
Department of Surgical Sciences, School of Veterinary Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA
Am J Physiol Regul Integr Comp Physiol 295:R111-22. 2008..These results suggest that the bladder-derived NGF acting via trk receptors at least partially mediates peripheral sensitization to mechanical stimuli associated with acute and subacute acrolein-induced cystitis...
Role of mast cells and protease-activated receptor-2 in cyclooxygenase-2 expression in urothelial cellsZun Yi Wang
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, Wisconsin 53719, USA
Am J Physiol Regul Integr Comp Physiol 297:R1127-35. 2009..These data indicate that there are functional interactions among mast cells, PAR-2 activation, and increased expression of COX-2 in bladder inflammation...
Bacterial cystitis is accompanied by increased peripheral thermal sensitivity in miceDale E Bjorling
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin, USA
J Urol 179:759-63. 2008..Visceral inflammation and pain associated with chemical cystitis produce increased sensitivity to noxious stimuli in the sacral dermatomes. We determined whether a similar sensitization occurs in response to bacterial cystitis...
The G protein-coupled receptor GPR30 inhibits human urothelial cell proliferationJian Teng
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin 53706, USA
Endocrinology 149:4024-34. 2008..These results suggest that GPR30-mediated inhibition of urothelial cell proliferation is the result of decreased cyclin D1 by down-regulation of activation protein-1 signaling...
Cannabinoid receptor 2 is increased in acutely and chronically inflamed bladder of ratsFabiola Voznika Merriam
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
Neurosci Lett 445:130-4. 2008..CB2 receptors may be a viable target for pharmacological treatment of bladder inflammation and associated pain...
Roles of estrogen receptor alpha and beta in modulating urothelial cell proliferationJian Teng
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
Endocr Relat Cancer 15:351-64. 2008..Increased expression of ERalpha may contribute to early induction of cyclin D1 and cyclin E during the cell cycle in bladder cancer cells...
Inhibition of fatty acid amide hydrolase suppresses referred hyperalgesia induced by bladder inflammationFabiola Voznika Merriam
Department of Surgical Sciences, School of Veterinary Medicine, Medical College of Wisconsin, Milwaukee, WI 53706, USA
BJU Int 108:1145-9. 2011....
Lack of TRPV1 inhibits cystitis-induced increased mechanical sensitivity in miceZun Yi Wang
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, 2015 Linden Drive, Madison, WI 53719, USA
Pain 139:158-67. 2008..Also, TRPV1 participates in development of visceral pain, as reflected by referred increased mechanosensitivity in peripheral tissues in the presence of visceral inflammation...
Evaluation of urothelial stretch-induced cyclooxygenase-2 expression in novel human cell culture and porcine in vivo ureteral obstruction modelsTravis J Jerde
The Uropharmacology and Endourology Research Laboratory, University of Wisconsin Medical School, Department of Pharmaceutical Science, Division of Urology, K6 561 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792, USA
J Pharmacol Exp Ther 317:965-72. 2006..Future elucidation of COX-2 signaling may identify novel therapeutic targets for treating stretch and distension of urinary tissues...
Nerve growth factor mediates peripheral mechanical hypersensitivity that accompanies experimental cystitis in miceSimone Domit Guerios
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, 2015 Linden Dr, Madison, 53706, USA
Neurosci Lett 392:193-7. 2006..This model of visceral pain causes increased sensitivity to peripheral application of mechanical stimuli. This effect is at least partially mediated by NGF, and the bladder may be the source of NGF in this process...
Arytenoid lateralization for treatment of laryngeal paralysis in 10 catsRobert J Hardie
Department of Surgical Sciences, School of Veterinary Medicine, The University of Wisconsin, Madison, WI 53706, USA
Vet Surg 38:445-51. 2009..To describe the signalment, history, clinical signs, surgical technique, and outcome for cats with laryngeal paralysis that had arytenoid lateralization...
Comparison of transdermal administration of fentanyl versus intramuscular administration of butorphanol for analgesia after onychectomy in catsKelly L Gellasch
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706, USA
J Am Vet Med Assoc 220:1020-4. 2002..Fentanyl appeared to provide equivalent analgesia to butorphanol in cats undergoing onychectomy. The primary advantage of using a TDF patch is that repeated injections are not required...
Accidental prehension and suspected transmucosal or oral absorption of fentanyl from a transdermal patch in a dogChad W Schmiedt
Department of Surgical Sciences, College of Veterinary Medicine, University of Wisconsin Madison, Madison, WI 53706 1102, USA
Vet Anaesth Analg 34:70-3. 2007..This clinical case documents the potential for neurologic sequelae, and bradycardia when fentanyl patches are used in animals to relieve postoperative pain...
Cyclooxygenase-2 expression is up-regulated in obstructed human ureterStephen Y Nakada
Divisions of Urology and Transplantation, Department of Surgery, University of Wisconsin Medical School, Madison, Wisconsin, USA
J Urol 168:1226-9. 2002..Using selective COX-2 inhibitors may be useful for treating prostanoid induced effects associated with ureteral obstruction...
Tumor necrosis factor-α induces expression and release of interleukin-6 by human urothelial cellsZun Yi Wang
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, 2015 Linden Drive, Madison, WI 53719, USA
Inflamm Res 60:525-32. 2011....
Acute acrolein-induced cystitis in miceDale E Bjorling
Department of Surgical Sciences, School of Veterinary, University of Wisconsin, Madison, WI 53706, USA
BJU Int 99:1523-9. 2007....
Surgical excision of primary canine rectal tumors by an anal approach in twenty-three dogsNichole A Danova
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
Vet Surg 35:337-40. 2006..CLINICAL RELEVANCE: An anal approach facilitated by rectal prolapse should be considered as a viable option for the surgical treatment of selected cases of tumors of the caudal aspect of the rectum in dogs...
Outcome of accelerated radiotherapy alone or accelerated radiotherapy followed by exenteration of the nasal cavity in dogs with intranasal neoplasia: 53 cases (1990-2002)William M Adams
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
J Am Vet Med Assoc 227:936-41. 2005..Exenteration after radiotherapy may increase the risk of chronic complications...
Use of intraluminal nitinol stents in the treatment of tracheal collapse in a dogKelly L Gellasch
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
J Am Vet Med Assoc 221:1719-23, 1714. 2002..The stents are composed of material that has characteristics similar to those of the trachea; nitinol stents may provide a method of supporting intrathoracic tracheal and mainstem bronchial collapse in dogs...
Stretch induction of cyclooxygenase-2 expression in human urothelial cells is calcium- and protein kinase C zeta-dependentTravis J Jerde
University of Wisconsin Medical School, Department of Surgery, Division of Urology, K6 561 Clinical Science Center 600 Highland Avenue, Madison, WI 53792, USA
Mol Pharmacol 73:18-26. 2008..Elucidating the signaling mechanism of stretch-induced COX-2 expression may identify therapeutic targets...
Results of vulvoplasty for treatment of recessed vulva in dogsScott P Hammel
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706, USA
J Am Anim Hosp Assoc 38:79-83. 2002..The incidences of UTI, vaginitis, and external irritation were greatly reduced after surgery...
Urinary incontinence in a dog with an ectopic ureteroceleSarah J Lautzenhiser
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53705, USA
J Am Anim Hosp Assoc 38:29-32. 2002..Ureterocelectomy was performed, and the dog remains continent 4 years after ureterocelectomy. Persistent urinary incontinence and urinary tract infection were attributed to failure to resect the ureterocele...
Celecoxib inhibits ureteral contractility and prostanoid releaseTravis J Jerde
Department of Surgery, Division of Urology, University of Wisconsin Medical School, Madison, Wisconsin 53792, USA
Urology 65:185-90. 2005..Animal experiments and clinical trials evaluating the safety and efficacy of celecoxib for the treatment of symptomatic ureteral obstruction are warranted...
Obstruction alters the effect of prostaglandin E2 on ureteral contractilityPatrick S Lowry
Department of Surgery, Division of Urology, University of Wisconsin Medical School, Madison, Wisconsin 53792-3236, USA
J Endourol 19:183-7. 2005..The response to PGE2 was accentuated by a longer duration of obstruction. Prostaglandin E2 may be a unique target for pharmacologic modulation in the treatment of symptoms associated with acute urinary obstruction...
Investigation of the potential heritability of persistent right aortic arch in GreyhoundsJessica M Gunby
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
J Am Vet Med Assoc 224:1120-2, 1111. 2004....
Neurogenic inflammation of the bladderDale E Bjorling
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, USA
Adv Exp Med Biol 539:551-83. 2003..It is exciting to contemplate the same approach to prevention and treatment of neurogenic bladder inflammation...
Ultrastructural basement membrane topography of the bladder epitheliumGeorge A Abrams
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Drive, Madison, WI 53711, USA
Urol Res 31:341-6. 2003..This information provides a rational basis for design of nanostructured biomaterials to produce composite grafts for repair or replacement of segments of the urinary tract...
Estrogen-induced proliferation of urothelial cells is modulated by nerve growth factorJian Teng
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin 53706, USA
Am J Physiol Renal Physiol 282:F1075-83. 2002..1 microl/ml). These data indicate that the effects of ER activation on HUC proliferation at least partly involve activation of trkA by NGF...
Decreased antigen-induced eicosanoid release in conjugated linoleic acid-fed guinea pigsLeah D Whigham
Department of Nutritional Sciences, College of Agricultural and Life Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA
Am J Physiol Regul Integr Comp Physiol 282:R1104-12. 2002..These data indicate that feeding CLA reduces lipid-derived inflammatory mediators produced by this type I hypersensitivity model...
Suppression of 15-hydroxyprostaglandin dehydrogenase messenger RNA concentration, protein expression, and enzymatic activity during human ureteral obstructionTravis J Jerde
Department of Surgery, Division of Urology, University of Wisconsin Medical School, G5 339 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792, USA
J Pharmacol Exp Ther 309:398-403. 2004..Modulation of prostanoid degradation may have therapeutic relevance in obstructive disorders of the ureter...
