Research Topics
| Vera A BittnerSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Detail Information
Publications
Women's angiographic vitamin and estrogen trial: design and methodsJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Control Clin Trials 23:708-27. 2002..Quantitative coronary angiography was performed at baseline and repeated after projected mean follow-up of 3 years...
Vitamin D levels do not predict cardiovascular events in statin-treated patients with stable coronary diseaseVera Bittner
University of Alabama at Birmingham, 35294 0007, USA
Am Heart J 164:387-93. 2012....
Postmenopausal hormone therapy and the risk of cardiovascular diseaseVera Bittner
University of Alabama at Birmingham, Division of Cardiovascular Disease, 701 19th Street South LHRB 310, Birmingham, Alabama 35294 0007, USA
Expert Opin Pharmacother 10:2041-53. 2009..Subsequent post hoc analyses of the Women's Health Initiative data have renewed enthusiasm for hormone therapy among younger postmenopausal women...
The triglyceride/high-density lipoprotein cholesterol ratio predicts all-cause mortality in women with suspected myocardial ischemia: a report from the Women's Ischemia Syndrome Evaluation (WISE)Vera Bittner
Department of Medicine, University of Alabama at Birmingham, USA
Am Heart J 157:548-55. 2009..The prognostic utility of the TG/HDL-C ratio, a marker for insulin resistance and small dense low-density lipoprotein particles, is unknown among high-risk women...
Influenza vaccination in secondary prevention: an opportunity missedVera Bittner
Division of Cardiovascular Disease, Preventive Cardiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Cardiopulm Rehabil Prev 27:202-7. 2007..Little is known about prevalence and correlates of FluVacc among patients with coronary heart disease enrolled in cardiac rehabilitation...
Perspectives on dyslipidemia and coronary heart disease in women: an updateVera Bittner
Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama, USA
Curr Opin Cardiol 21:602-7. 2006..This review summarizes observational studies of lipoproteins and coronary heart disease risk and randomized trials of lipid-lowering therapy among women and reviews progress in the implementation of proven therapies in clinical practice...
Cardiac rehabilitation as secondary prevention centerVera Bittner
Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama, USA
Coron Artery Dis 17:211-8. 2006..Future research directions are outlined...
Perspectives on dyslipidemia and coronary heart disease in womenVera Bittner
Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Am Coll Cardiol 46:1628-35. 2005....
Remnant-like lipoproteins, hormone therapy, and angiographic and clinical outcomes: the Women's Angiographic Vitamin & Estrogen TrialVera Bittner
University of Alabama at Birmingham, 35294, USA
Am Heart J 148:293-9. 2004....
Non-high-density lipoprotein cholesterol: an alternate target for lipid-lowering therapyVera Bittner
Division of Cardiovascular Disease, University of Alabama at Birmingham, 35294, USA
Prev Cardiol 7:122-6; quiz 129-30. 2004..In the National Cholesterol Education Program Adult Treatment Panel III report, non-HDL cholesterol has been designated a secondary target of therapy among patients with hypertriglyceridemia...
Women and coronary heart disease risk factorsVera Bittner
Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, LHRB 310 UAB Station, Birmingham, Alabama 35294, USA
J Cardiovasc Risk 9:315-22. 2002....
Non-high-density lipoprotein cholesterol levels predict five-year outcome in the Bypass Angioplasty Revascularization Investigation (BARI)Vera Bittner
University of Alabama at Birmingham, Birmingham, AL 35294, USA
Circulation 106:2537-42. 2002..26 mmol/L. It is not known whether non-HDL-C relates to prognosis among patients with coronary heart disease...
Treatment of dyslipidemia in pre- and postmenopausal women with and without known atherosclerotic cardiovascular diseaseV Bittner
Division of Cardiovascular Disease, University of Alabama at Birmingham, UAB Station LHR 310, Birmingham, AL 35294, USA
Curr Cardiol Rep 3:401-7. 2001....
Non-high-density lipoprotein cholesterol and cardiovascular diseaseVera Bittner
Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Curr Opin Lipidol 14:367-71. 2003....
Effect of coronary angiography on use of lipid-lowering agents in women: a report from the Women's Ischemia Syndrome Evaluation (WISE) study. For the WISE InvestigatorsV Bittner
Division of Cardiovascular Disease, University of Alabama at Birmingham, 35294, USA
Am J Cardiol 85:1083-8. 2000..Intensification of lipid-lowering therapy was not apparent 6 weeks after coronary angiography in women with newly diagnosed CAD or among women whose diagnosis was confirmed...
Correlates of high HDL cholesterol among women with coronary heart diseaseV Bittner
University of Alabama at Birmingham, 35294, USA
Am Heart J 139:288-96. 2000....
Hormone replacement therapy in clinical cardiologyV Bittner
Division of Cardiovascular Disease, University of Alabama at Birmingham, LHR 310A, University Station, Birmingham, AL 35294, USA
Cardiol Rev 8:57-64. 2000..For now, a cautionary approach to hormone replacement therapy appears warranted, at least among postmenopausal women with established coronary artery disease...
Referral patterns to a University-based cardiac rehabilitation programV Bittner
Department of Medicine, University of Alabama at Birmingham, 35294 0007, USA
Am J Cardiol 83:252-5, A5. 1999..Only 8.7% of eligible patients were referred, suggesting that more education targeting physicians, patients, and insurers is needed and barriers to participation must be systematically addressed...
Cholesterol-lowering medication, cholesterol level, and reproductive hormones in women: the Women's Ischemia Syndrome Evaluation (WISE)C Noel Bairey Merz
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
Am J Med 113:723-7. 2002..We also sought to evaluate this association, independent of statin use, particularly among premenopausal women of childbearing age...
The economic burden of angina in women with suspected ischemic heart disease: results from the National Institutes of Health--National Heart, Lung, and Blood Institute--sponsored Women's Ischemia Syndrome EvaluationLeslee J Shaw
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, Calif, USA
Circulation 114:894-904. 2006..Few data exist regarding the type and intensity of resource consumption in women with chest pain after coronary angiography...
Importance of socioeconomic status as a predictor of cardiovascular outcome and costs of care in women with suspected myocardial ischemia. Results from the National Institutes of Health, National Heart, Lung and Blood Institute-sponsored Women's Ischemia Leslee J Shaw
Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30306, USA
J Womens Health (Larchmt) 17:1081-92. 2008..For women, who are more likely to live in poverty, defining the clinical and economic impact of socioeconomic factors may aid in defining redistributive policies to improve healthcare quality...
Hypoestrogenemia of hypothalamic origin and coronary artery disease in premenopausal women: a report from the NHLBI-sponsored WISE studyC Noel Bairey Merz
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
J Am Coll Cardiol 41:413-9. 2003..We sought to evaluate hypoestrogenemia of hypothalamic origin and its association with angiographic coronary artery disease (CAD) in premenopausal women...
Exercise as a treatment for the risk of cardiovascular diseaseBilal Aijaz
Division of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, LHRB 306 701, 19th Street South, Birmingham, AL, 35294, USA
Curr Treat Options Cardiovasc Med 12:329-41. 2010..Health care providers have an opportunity and a responsibility to include exercise counseling in routine office visits...
Variations in prevalent cardiovascular disease and future risk by metabolic syndrome classification in the REasons for Geographic and Racial Differences in Stroke (REGARDS) studyTodd M Brown
Division of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, AL, USA
Am Heart J 159:385-91. 2010..The International Diabetes Federation (IDF) and Adult Treatment Panel (ATP) III define metabolic syndrome (MetSyn) differently, with unclear implications for cardiovascular disease (CVD) risk...
Metabolic syndrome and coronary angiographic disease progression: the Women's Angiographic Vitamin & Estrogen trialJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Am Heart J 146:439-45. 2003....
Outcomes at one-year follow-up of women and men with coronary artery disease discharged from cardiac rehabilitation: what benefits are maintained?Ritesh Gupta
Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, 35294 0007, USA
J Cardiopulm Rehabil Prev 27:11-8; quiz 19-20. 2007..Little is known about which benefits achieved during cardiac rehabilitation (CR) are maintained 1 year after CR discharge and whether there are any gender-specific differences...
Does prevalence of the metabolic syndrome in women with coronary artery disease differ by the ATP III and IDF criteria?Todd M Brown
Health Services Research Training Program, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
J Womens Health (Larchmt) 17:841-7. 2008..Whether the IDF definition identifies a greater prevalence of the metabolic syndrome than the ATP III definition in women with coronary artery disease (CAD) is unknown...
Relations between endogenous androgens and estrogens in postmenopausal women with suspected ischemic heart diseaseGlenn D Braunstein
Department of Medicine, Room 2119, Plaza Level, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, California 90048, USA
J Clin Endocrinol Metab 93:4268-75. 2008..If so, then epidemiologic studies that examine the association between androgens and pathological processes should adjust the results for the independent effect of estrogens...
Predictors of cardiac rehabilitation referral in coronary artery disease patients: findings from the American Heart Association's Get With The Guidelines ProgramTodd M Brown
University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Am Coll Cardiol 54:515-21. 2009..Our purpose was to determine factors independently associated with cardiac rehabilitation referral, which are currently not well described at a national level...
Drugs are not enough: the metabolic syndrome--a call for intensive therapeutic lifestyle changeTodd M Brown
Division of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
J Cardiometab Syndr 4:20-5. 2009..More emphasis on therapeutic lifestyle change in addition to intensive pharmacologic therapy is needed to reduce MetS prevalence in patients with coronary artery disease...
Lipoprotein abnormalities related to women's healthVera Bittner
Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama 35294
Am J Cardiol 90:77i-84i. 2002..In contrast, lifestyle changes and pharmacological lipid-lowering therapy have been shown to favorably influence the natural course of atherosclerotic disease and reduce cardiovascular events in men and women...
Optimizing risk stratification in cardiac rehabilitation with inclusion of a comorbidity indexGilbert J Zoghbi
Division of Cardiovascular Disease, University of Alabama at Birmingham, 35294 0007, USA
J Cardiopulm Rehabil 24:8-13; quiz 14-5. 2004..This study was designed to ascertain the prevalence of noncardiac comorbidities among CR patients, and to assess their relation to the current risk stratification algorithm for clinical events...
Glucose, blood pressure, and lipid control in older people with and without diabetes mellitus: the Cardiovascular Health StudyNicholas L Smith
Department of Medicine, Cardiovascular Health Research Unit, University of Washington, 1730 Minor Avenue, Seattle, WA 98101, USA
J Am Geriatr Soc 50:416-23. 2002....
Depression, the metabolic syndrome and cardiovascular riskViola Vaccarino
Division of Cardiology, Department of Medicine, Emory University School of Medicine, 1256 Briarcliff Road NE, Suite 1 North, Atlanta, GA 30306, USA
Psychosom Med 70:40-8. 2008..The relationship between depression and the metabolic syndrome is unclear, and whether metabolic syndrome explains the association between depression and cardiovascular disease (CVD) risk is unknown...
Depression, inflammation, and incident cardiovascular disease in women with suspected coronary ischemia: the National Heart, Lung, and Blood Institute-sponsored WISE studyViola Vaccarino
Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia 30306, USA
J Am Coll Cardiol 50:2044-50. 2007..The purpose of this study was to examine prospectively whether inflammation explains the relationship between depression and cardiovascular disease (CVD)...
Comparison of baseline characteristics and outcomes in younger and older patients completing cardiac rehabilitationSanjay Maniar
School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
J Cardiopulm Rehabil Prev 29:220-9. 2009..The present study compares baseline characteristics and CR outcomes between younger and older patients participating in CR...
Secondary prevention outcomes among black and white cardiac rehabilitation patientsBonnie K Sanderson
Division of Cardiovascular Disease, Preventive Cardiology, University of Alabama at Birmingham, AL 35294, USA
Am Heart J 153:980-6. 2007..It is unknown if cardiac rehabilitation (CR) narrows the gap in risk factor control between black and white patients. Thus, we compared baseline characteristics and secondary prevention outcomes between black and white CR patients...
Racial differences of lipoprotein subclass distributions in postmenopausal womenAmit N Vora
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Ethn Dis 18:176-80. 2008..We assessed racial differences in lipoprotein particle size, a marker of atherosclerosis risk, among women with coronary disease...
Physical activity patterns among women in rural AlabamaBonnie K Sanderson
Department of Medicine, Divison of Cardiovascular Disease, University of Alabama at Birmingham, 35294, USA
Am J Health Behav 27:311-21. 2003..To explore factors associated with physically active women in a rural community...
Women in cardiac rehabilitationVera Bittner
Division of Cardiovascular Disease, University of Alabama at Birmingham, USA
J Am Med Womens Assoc 58:227-35. 2003....
Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part II: gender differences in presentation, diagnosis, and outcome with regard to gender-based pathophysiology of atherosclerosis and macrovascular and microvascular corC Noel Bairey Merz
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
J Am Coll Cardiol 47:S21-9. 2006..Additionally, innovative cardiovascular imaging techniques will be discussed. Finally, we identify critical areas of further inquiry needed to advance this new gender-specific IHD understanding into improved outcomes for women...
Association of race and sex with risk of incident acute coronary heart disease eventsMonika M Safford
School of Medicine, University of Alabama, Birmingham, AL 35294, USA
JAMA 308:1768-74. 2012..It is unknown whether long-standing disparities in incidence of coronary heart disease (CHD) among US blacks and whites persist...
Biomarkers of atherosclerosis: clinical applicationsTodd M Brown
Preventive Cardiology, University of Alabama at Birmingham, Division of Cardiovascular Disease, 701 19th Street South LHRB 310, Birmingham, AL 35294 0007, USA
Curr Cardiol Rep 10:497-504. 2008..We review the recently published literature on blood-based biomarkers and examine whether incorporating these markers may improve clinical decision making...
Diabetes mellitus, hypothalamic hypoestrogenemia, and coronary artery disease in premenopausal women (from the National Heart, Lung, and Blood Institute sponsored WISE study)Bina Ahmed
Department of Medicine, Division of Cardiology, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
Am J Cardiol 102:150-4. 2008..The presence of both DM and HHE predicted a greater burden of angiographic CAD. Prospective research is warranted to better understand causal relations between DM, endogenous hormones, and MACE in premenopausal women...
Cardiac rehabilitation and women: what keeps them away?Bonnie K Sanderson
University of Alabama at Birmingham, 35294, USA
J Cardiopulm Rehabil Prev 30:12-21. 2010..Cardiac rehabilitation (CR) is underutilized, especially among women. The goal of this study was to examine CR referral and enrollment patterns among eligible women and identify factors associated with utilization...
Past oral contraceptive use and angiographic coronary artery disease in postmenopausal women: data from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome EvaluationC Noel Bairey Merz
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute and Medical Center, Los Angeles, California, USA
Fertil Steril 85:1425-31. 2006..To evaluate past oral contraceptive use and angiographic coronary artery disease in women...
Postmenopausal women with a history of irregular menses and elevated androgen measurements at high risk for worsening cardiovascular event-free survival: results from the National Institutes of Health--National Heart, Lung, and Blood Institute sponsored WLeslee J Shaw
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
J Clin Endocrinol Metab 93:1276-84. 2008..Women with polycystic ovary syndrome (PCOS) have a greater clustering of cardiac risk factors. However, the link between PCOS and cardiovascular (CV) disease is incompletely described...
Factors associated with the failure of patients to complete cardiac rehabilitation for medical and nonmedical reasonsBonnie K Sanderson
School of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
J Cardiopulm Rehabil 23:281-9. 2003..The purposes of this study were to describe completion rates in a hospital-based outpatient CR program, and to identify factors associated with patients failing to complete CR because of nonmedical and medical reasons...
Personal, social, and physical environmental correlates of physical activity in rural African-American women in AlabamaBonnie K Sanderson
Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Am J Prev Med 25:30-7. 2003..Physical inactivity is prevalent among African-American women in rural Alabama. The purpose of this study was to explore personal, social, and physical environmental factors associated with activity to help plan interventions...
Accuracy of the triglyceride to high-density lipoprotein cholesterol ratio for prediction of the low-density lipoprotein phenotype BViktor Hanak
Department of Medicine, Carraway Methodist Medical Center, Birmingham, Alabama, USA
Am J Cardiol 94:219-22. 2004..8. The ratio was reliable for identifying LDL phenotype B in men and women...
Prehospital delay in individuals with acute coronary disease: concordance of medical records and follow-up phone interviewsRobert J Goldberg
Department of Medicine, University of Massachusetts Medical School, Worcester, Mass. 01655, USA
Cardiology 97:159-65. 2002..These results suggest that a telephone interview carried out several months following hospitalization for acute coronary disease may not provide sufficiently reliable information about prehospital delay...
Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part I: gender differences in traditional and novel risk factors, symptom evaluation, and gender-optimized diagnostic strategiesLeslee J Shaw
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
J Am Coll Cardiol 47:S4-S20. 2006....
Practical interpretation of 6-minute walk data using healthy adult reference equationsBonnie Sanderson
Division of Cardiovascular Disease, Preventive Cardiology, and CardioPulmonary Rehabilitation, University Hospital, University of Alabama at Birmingham, 35294, USA
J Cardiopulm Rehabil 26:167-71. 2006
Migraines, angiographic coronary artery disease and cardiovascular outcomes in womenBina Ahmed
Division of Cardiology, Department of Medicine, Cedars-Sinai Research Institute, Cedars-Sinai Medical Center, Los Angeles, Calif, USA
Am J Med 119:670-5. 2006..We could not support an association between migraines and cardiovascular events or death. Further research studying the common pathophysiology underlying migraines and cardiovascular disease is warranted...
Total estrogen time and obstructive coronary disease in women: insights from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE)C Noel Bairey Merz
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
J Womens Health (Larchmt) 18:1315-22. 2009..The aim of this study was to evaluate the relationships between detailed measurements of endogenous and exogenous estrogen exposure time with angiographic CAD and major adverse cardiovascular events...
Women in cardiac rehabilitation: outcomes and identifying risk for dropoutBonnie K Sanderson
Division of Cardiovascular Disease, Department and School of Medicine, University of Alabama, Birmingham, Alabama 35294, USA
Am Heart J 150:1052-8. 2005..The purposes of this study were to (1) compare baseline characteristics between women who completed and did not complete CR, (2) identify factors associated with women completing CR, and (3) describe outcomes among completers...
Assessing patient recall of discharge instructions for acute myocardial infarctionBonnie K Sanderson
University Hospital, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Healthc Qual 31:25-33; quiz 34. 2009..Quality improvement strategies are needed to guide more effective provider-patient communication...
The 6-minute walk test: how important is the learning effect?Grace Wu
University of Alabama School of Medicine, University of Alabama at Birmingham, AL 35294 0007, USA
Am Heart J 146:129-33. 2003..An initial learning effect with repeated administration is well documented, but it is unknown whether this learning effect persists with time...
Intensive lipid lowering with atorvastatin in patients with coronary artery disease, diabetes, and chronic kidney diseaseJames Shepherd
University of Glasgow, United Kingdom
Mayo Clin Proc 83:870-9. 2008....
Research Grants
- ACTION - A CHF Trial Investigating Outcomes of ExerciseVera Bittner; Fiscal Year: 2005..The trial will take place over 5 years with an initial 6 months for planning, training, and implementation; 3 years of enrollment; 1 year of follow-up; and 6 months for close out, analysis, and presentation. ..
