Gregory P Bisson

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Early mortality and AIDS progression despite high initial antiretroviral therapy adherence and virologic suppression in Botswana
    Katherine T Steele
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e20010. 2011
  2. doi request reprint Early versus delayed antiretroviral therapy and cerebrospinal fluid fungal clearance in adults with HIV and cryptococcal meningitis
    Gregory P Bisson
    Department of Medicine, Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, and The Children s Hospital of Philadelphia, Philadelphia, PA 19104 6021, USA
    Clin Infect Dis 56:1165-73. 2013
  3. pmc Multiple oncogenic viruses identified in Ocular surface squamous neoplasia in HIV-1 patients
    Kenneth O Simbiri
    Department of Microbiology, and Abramson Comprehensive Cancer Center, Tumor Virology Program, University of Pennsylvania, 202A Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104 6076, USA
    Infect Agent Cancer 5:6. 2010
  4. pmc Lost but not forgotten--the economics of improving patient retention in AIDS treatment programs
    Gregory P Bisson
    University of Pennsylvania School of Medicine, Department of Medicine, Division of Infectious Diseases, Philadelphia, Pennsylvania, USA
    PLoS Med 6:e1000174. 2009
  5. ncbi request reprint Cryptococcus and lymphocytic meningitis in Botswana
    Gregory P Bisson
    Infectious Diseases Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    S Afr Med J 98:724-5. 2008
  6. pmc A simple novel method for determining mortality rates in HIV treatment programs worldwide
    Gregory P Bisson
    University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    PLoS Med 8:e1000392. 2011
  7. pmc Overestimates of survival after HAART: implications for global scale-up efforts
    Gregory P Bisson
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    PLoS ONE 3:e1725. 2008
  8. ncbi request reprint Diagnostic accuracy of CD4 cell count increase for virologic response after initiating highly active antiretroviral therapy
    Gregory P Bisson
    Department of Medicine, Division of Infectious Diseases, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania19104 6021, USA
    AIDS 20:1613-9. 2006
  9. ncbi request reprint Antiretroviral failure despite high levels of adherence: discordant adherence-response relationship in Botswana
    Gregory P Bisson
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Acquir Immune Defic Syndr 49:107-10. 2008
  10. pmc The use of HAART is associated with decreased risk of death during initial treatment of cryptococcal meningitis in adults in Botswana
    Gregory P Bisson
    Department of Medicine, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
    J Acquir Immune Defic Syndr 49:227-9. 2008

Research Grants

  1. Immunology and Outcomes after HAART in HIV/TB Coinfection
    Gregory P Bisson; Fiscal Year: 2010
  2. Immunology and Outcomes after HAART in HIV/TB Coinfection
    Gregory Bisson; Fiscal Year: 2009
  3. Effect of GBV-C on HIV
    Gregory Bisson; Fiscal Year: 2007
  4. Immunology and Outcomes after HAART in HIV/TB Coinfection
    Gregory P Bisson; Fiscal Year: 2010

Collaborators

Detail Information

Publications19

  1. pmc Early mortality and AIDS progression despite high initial antiretroviral therapy adherence and virologic suppression in Botswana
    Katherine T Steele
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e20010. 2011
    ..We sought to determine the relationship between very early ART adherence and early adverse outcomes in HIV-infected adults in Botswana...
  2. doi request reprint Early versus delayed antiretroviral therapy and cerebrospinal fluid fungal clearance in adults with HIV and cryptococcal meningitis
    Gregory P Bisson
    Department of Medicine, Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, and The Children s Hospital of Philadelphia, Philadelphia, PA 19104 6021, USA
    Clin Infect Dis 56:1165-73. 2013
    ..This study tested the hypothesis that initiation of ART during initial treatment of HIV/CM would improve CSF clearance of C. neoformans...
  3. pmc Multiple oncogenic viruses identified in Ocular surface squamous neoplasia in HIV-1 patients
    Kenneth O Simbiri
    Department of Microbiology, and Abramson Comprehensive Cancer Center, Tumor Virology Program, University of Pennsylvania, 202A Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104 6076, USA
    Infect Agent Cancer 5:6. 2010
    ..Ocular surface squamous neoplasia (OSSN) is a rare cancer that has increased in incidence with the HIV pandemic in Africa. The underlying cause of this cancer in HIV-infected patients from Botswana is not well defined...
  4. pmc Lost but not forgotten--the economics of improving patient retention in AIDS treatment programs
    Gregory P Bisson
    University of Pennsylvania School of Medicine, Department of Medicine, Division of Infectious Diseases, Philadelphia, Pennsylvania, USA
    PLoS Med 6:e1000174. 2009
    ..Gregory Bisson and Jeffrey Stringer discuss the implications of a new study showing how loss to follow-up affects the effectiveness of a public sector HIV program in Côte d'Ivoire...
  5. ncbi request reprint Cryptococcus and lymphocytic meningitis in Botswana
    Gregory P Bisson
    Infectious Diseases Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    S Afr Med J 98:724-5. 2008
    ..Moreover, almost 70% of CSF samples with significant lymphocytosis did not yield a pathogen, suggesting that many causes of lymphocytic meningitis go undiagnosed...
  6. pmc A simple novel method for determining mortality rates in HIV treatment programs worldwide
    Gregory P Bisson
    University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    PLoS Med 8:e1000392. 2011
    ....
  7. pmc Overestimates of survival after HAART: implications for global scale-up efforts
    Gregory P Bisson
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    PLoS ONE 3:e1725. 2008
    ..Determining definitive outcomes of these lost patients, and the effects of losses to follow-up on estimates of survival and risk factors for death after HAART, are key to monitoring the effectiveness of global HAART scale-up efforts...
  8. ncbi request reprint Diagnostic accuracy of CD4 cell count increase for virologic response after initiating highly active antiretroviral therapy
    Gregory P Bisson
    Department of Medicine, Division of Infectious Diseases, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania19104 6021, USA
    AIDS 20:1613-9. 2006
    ..To derive and internally validate a clinical prediction rule for virologic response based on CD4 cell count increase after initiation of HAART in a resource-limited setting...
  9. ncbi request reprint Antiretroviral failure despite high levels of adherence: discordant adherence-response relationship in Botswana
    Gregory P Bisson
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Acquir Immune Defic Syndr 49:107-10. 2008
    ..Although adherence to antiretroviral therapy may be higher in sub-Saharan Africa, knowledge regarding the magnitude of adherence needed to maintain virological suppression in this setting is limited...
  10. pmc The use of HAART is associated with decreased risk of death during initial treatment of cryptococcal meningitis in adults in Botswana
    Gregory P Bisson
    Department of Medicine, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
    J Acquir Immune Defic Syndr 49:227-9. 2008
    ..The objective of this study was to evaluate outcomes among adults with a first episode of cryptococcal meningitis (CM), comparing those on highly active antiretroviral therapy (HAART) with those not on HAART...
  11. pmc Early immunologic failure is associated with early mortality among advanced HIV-infected adults initiating antiretroviral therapy with active tuberculosis
    Shruthi Ravimohan
    Department of Medicine, Division of Infectious Diseases
    J Infect Dis 208:1784-93. 2013
    ..The relationship between antiretroviral therapy (ART) response and early mortality after ART initiation is unknown. We hypothesized that early mortality is associated with decreased early immunologic response to ART...
  12. pmc Pharmacy refill adherence compared with CD4 count changes for monitoring HIV-infected adults on antiretroviral therapy
    Gregory P Bisson
    Department of Medicine, Division of Infectious Diseases, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
    PLoS Med 5:e109. 2008
    ....
  13. pmc Upregulation of the phthiocerol dimycocerosate biosynthetic pathway by rifampin-resistant, rpoB mutant Mycobacterium tuberculosis
    Gregory P Bisson
    Division of Infectious Diseases, Department of Medicine, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Bacteriol 194:6441-52. 2012
    ..These findings may assist in developing novel methods to diagnose and treat drug-resistant M. tuberculosis infections...
  14. pmc Isoniazid-resistant tuberculous meningitis, United States, 1993-2005
    Christopher Vinnard
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Emerg Infect Dis 17:539-42. 2011
    ..Foreign-born patients were more likely to be infected with an isoniazid-resistant strain...
  15. ncbi request reprint Out-of-pocket costs of HAART limit HIV treatment responses in Botswana's private sector
    Gregory P Bisson
    Division of Infectious Disease, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    AIDS 20:1333-6. 2006
    ..001]. HAART costs should be minimized as scale-up efforts in sub-Saharan Africa progress...
  16. pmc HIV infection and glycemic response to newly initiated diabetic medical therapy
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, 3rd Floor, Silverstein Building, Ste E, Philadelphia, PA 19104, USA
    AIDS 26:2087-95. 2012
    ..The objective of this study was to compare the effectiveness of initial diabetic medical therapy in patients with and without HIV infection...
  17. ncbi request reprint Effect of GB virus C viremia on HIV acquisition and HIV set-point
    Gregory P Bisson
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    AIDS 19:1910-2. 2005
    ..32; 95% confidence interval 0.6-2.6). Pre-existing GBV-C viremia at the time of HIV acquisition was also not associated with lower plasma HIV-RNA levels...
  18. pmc Isoniazid resistance and death in patients with tuberculous meningitis: retrospective cohort study
    Christopher Vinnard
    Department of Medicine, Division of Infectious Diseases, University of Pennsylvania School of Medicine, 502 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104, USA
    BMJ 341:c4451. 2010
    ..To determine whether initial isoniazid resistance is associated with death during the treatment of tuberculous meningitis...
  19. pmc Dose-dependent activity of pyrazinamide in animal models of intracellular and extracellular tuberculosis infections
    Zahoor Ahmad
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Antimicrob Agents Chemother 55:1527-32. 2011
    ..Clinical studies are warranted to investigate the sterilizing activity and tolerability of higher doses of pyrazinamide in combination tuberculosis regimens...

Research Grants5

  1. Immunology and Outcomes after HAART in HIV/TB Coinfection
    Gregory P Bisson; Fiscal Year: 2010
    ..Conducted as a prospective cohort study in Gaborone, Botswana, the project will yield important information to clinical care and public health efforts designed to improve the outcomes in global antiretroviral therapy scale-up efforts. ..
  2. Immunology and Outcomes after HAART in HIV/TB Coinfection
    Gregory Bisson; Fiscal Year: 2009
    ..Conducted as a prospective cohort study in Gaborone, Botswana, the project will yield important information to clinical care and public health efforts designed to improve the outcomes in global antiretroviral therapy scale-up efforts. ..
  3. Effect of GBV-C on HIV
    Gregory Bisson; Fiscal Year: 2007
    ..This aim will be examined using a cohort study with GBV-C viremia at baseline as the exposure and viral load breakthrough as the outcome. Analysis will examine effect of GBV-C viremia on time to virologic breakthrough. ..
  4. Immunology and Outcomes after HAART in HIV/TB Coinfection
    Gregory P Bisson; Fiscal Year: 2010
    ..Conducted as a prospective cohort study in Gaborone, Botswana, the project will yield important information to clinical care and public health efforts designed to improve the outcomes in global antiretroviral therapy scale-up efforts. ..