Amy Bishop

Summary

Affiliation: University of Alabama in Huntsville
Country: USA

Publications

  1. ncbi A key role for heme oxygenase-1 in nitric oxide resistance in murine motor neurons and glia
    Amy Bishop
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Biochem Biophys Res Commun 325:3-9. 2004
  2. ncbi NO signaling in the CNS: from the physiological to the pathological
    Amy Bishop
    Department of Biological Sciences, University of Alabama at Huntsville, Huntsville, Alabama 35899, USA
    Toxicology 208:193-205. 2005
  3. pmc Mitigation of peroxynitrite-mediated nitric oxide (NO) toxicity as a mechanism of induced adaptive NO resistance in the CNS
    Amy Bishop
    Department of Biological Sciences, University of Alabama at Huntsville, Huntsville, Alabama 35899, USA
    J Neurochem 109:74-84. 2009
  4. pmc Differential sensitivity of oligodendrocytes and motor neurons to reactive nitrogen species: implications for multiple sclerosis
    Amy Bishop
    Department of Biological Sciences, University of Alabama in Huntsville, Huntsville, Alabama 35899, USA
    J Neurochem 109:93-104. 2009
  5. ncbi Induced adaptive resistance to oxidative stress in the CNS: a discussion on possible mechanisms and their therapeutic potential
    Amy Bishop
    Department of Medicine, Harvard Medical School, Department of Cardiovascular Research, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Curr Drug Metab 4:171-84. 2003

Detail Information

Publications5

  1. ncbi A key role for heme oxygenase-1 in nitric oxide resistance in murine motor neurons and glia
    Amy Bishop
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Biochem Biophys Res Commun 325:3-9. 2004
    ..These results confirm the in vivo role of HO1 as a front-line defense against NO toxicity in neuronal cells...
  2. ncbi NO signaling in the CNS: from the physiological to the pathological
    Amy Bishop
    Department of Biological Sciences, University of Alabama at Huntsville, Huntsville, Alabama 35899, USA
    Toxicology 208:193-205. 2005
    ..Understanding how the actions of NO are transduced in the cell will lead us to more targeted application of therapies such as IAR...
  3. pmc Mitigation of peroxynitrite-mediated nitric oxide (NO) toxicity as a mechanism of induced adaptive NO resistance in the CNS
    Amy Bishop
    Department of Biological Sciences, University of Alabama at Huntsville, Huntsville, Alabama 35899, USA
    J Neurochem 109:74-84. 2009
    ..This data indicate that IAR is an HO1-dependent mechanism that prevents peroxynitrite-mediated NO toxicity in motor neurons, thereby elucidating therapeutic targets for the mitigation of CNS disease and injury...
  4. pmc Differential sensitivity of oligodendrocytes and motor neurons to reactive nitrogen species: implications for multiple sclerosis
    Amy Bishop
    Department of Biological Sciences, University of Alabama in Huntsville, Huntsville, Alabama 35899, USA
    J Neurochem 109:93-104. 2009
    ..Preliminary studies suggest oligodendrocytes release a soluble factor that protects motor neurons. Our findings challenge the current paradigm that oligodendrocytes are the exclusive target of multiple sclerosis pathology...
  5. ncbi Induced adaptive resistance to oxidative stress in the CNS: a discussion on possible mechanisms and their therapeutic potential
    Amy Bishop
    Department of Medicine, Harvard Medical School, Department of Cardiovascular Research, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Curr Drug Metab 4:171-84. 2003
    ..In fact, a variety of possible mechanisms may be involved in induced resistance to NO in the CNS. Ultimately elucidating these mechanisms will enable us to modulate them for therapeutic potential...