B Birmaher

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc The Adolescent Depression Rating Scale (ADRS): a validation study
    Anne Revah-Levy
    INSERM U669, Universite Paris Sud 11, Centre Hospitalier V, Dupouy, 95107 Argenteuil, France
    BMC Psychiatry 7:2. 2007
  2. ncbi request reprint Clinical outcome after short-term psychotherapy for adolescents with major depressive disorder
    B Birmaher
    Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, PA 15213, USA
    Arch Gen Psychiatry 57:29-36. 2000
  3. ncbi request reprint Fluoxetine for the treatment of childhood anxiety disorders
    Boris Birmaher
    Department of Child Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 42:415-23. 2003
  4. ncbi request reprint Course and outcome of child and adolescent major depressive disorder
    Boris Birmaher
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, 3811 O Hara Street, Pittsburgh, PA 15213 3811, USA
    Child Adolesc Psychiatr Clin N Am 11:619-37, x. 2002
  5. ncbi request reprint Randomized, controlled trial of amitriptyline versus placebo for adolescents with "treatment-resistant" major depression
    B Birmaher
    Division of Child Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, USA
    J Am Acad Child Adolesc Psychiatry 37:527-35. 1998
  6. ncbi request reprint Psychometric properties of the Screen for Child Anxiety Related Emotional Disorders (SCARED): a replication study
    B Birmaher
    Division of Child Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 38:1230-6. 1999
  7. ncbi request reprint Biological studies in depressed children and adolescents
    B Birmaher
    University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
    Int J Neuropsychopharmacol 4:149-57. 2001
  8. ncbi request reprint Growth hormone secretion in children and adolescents at high risk for major depressive disorder
    B Birmaher
    Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Arch Gen Psychiatry 57:867-72. 2000
  9. ncbi request reprint Cognitive and family therapies for adolescent depression: treatment specificity, mediation, and moderation
    D J Kolko
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
    J Consult Clin Psychol 68:603-14. 2000
  10. ncbi request reprint Screen for Child Anxiety-Related Emotional Disorders (SCARED): convergent and divergent validity
    S Monga
    Child Psychiatry Department, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA
    Depress Anxiety 12:85-91. 2000

Collaborators

Detail Information

Publications81

  1. pmc The Adolescent Depression Rating Scale (ADRS): a validation study
    Anne Revah-Levy
    INSERM U669, Universite Paris Sud 11, Centre Hospitalier V, Dupouy, 95107 Argenteuil, France
    BMC Psychiatry 7:2. 2007
    ..To examine the psychometric properties of the Adolescent Depression Rating Scale (ADRS), a new measure was specifically designed to evaluate adolescent depression...
  2. ncbi request reprint Clinical outcome after short-term psychotherapy for adolescents with major depressive disorder
    B Birmaher
    Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, PA 15213, USA
    Arch Gen Psychiatry 57:29-36. 2000
    ..However, the long-term impact of brief psychosocial interventions on the course of adolescent depression is not well established...
  3. ncbi request reprint Fluoxetine for the treatment of childhood anxiety disorders
    Boris Birmaher
    Department of Child Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 42:415-23. 2003
    ..To assess the efficacy and tolerability of fluoxetine for the acute treatment of children and adolescents with generalized anxiety disorder, separation anxiety disorder, and/or social phobia...
  4. ncbi request reprint Course and outcome of child and adolescent major depressive disorder
    Boris Birmaher
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, 3811 O Hara Street, Pittsburgh, PA 15213 3811, USA
    Child Adolesc Psychiatr Clin N Am 11:619-37, x. 2002
    ..Depressed youth who present with psychosis, psychomotor retardation, pharmacological induced hypomania/mania, and/or family history of bipolar disorder are at high risk to develop bipolar disorder...
  5. ncbi request reprint Randomized, controlled trial of amitriptyline versus placebo for adolescents with "treatment-resistant" major depression
    B Birmaher
    Division of Child Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, USA
    J Am Acad Child Adolesc Psychiatry 37:527-35. 1998
    ..To assess the response to a serotonergic/noradrenergic tricyclic antidepressant, amitriptyline (AMI), in a group of adolescents with treatment-resistant major depressive disorder (MDD)...
  6. ncbi request reprint Psychometric properties of the Screen for Child Anxiety Related Emotional Disorders (SCARED): a replication study
    B Birmaher
    Division of Child Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 38:1230-6. 1999
    ..To replicate and extend work on the psychometric properties of the Screen for Child Anxiety Related Emotional Disorders (SCARED), a child and parent self-report instrument used to screen for children with anxiety disorders...
  7. ncbi request reprint Biological studies in depressed children and adolescents
    B Birmaher
    University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
    Int J Neuropsychopharmacol 4:149-57. 2001
    ..Also, these and other studies using more sophisticated methods (e.g. functional MRI) aimed at elucidating the interrelationship between biological and other risk factors are needed...
  8. ncbi request reprint Growth hormone secretion in children and adolescents at high risk for major depressive disorder
    B Birmaher
    Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Arch Gen Psychiatry 57:867-72. 2000
    ..In this study, we sought to determine whether GH secretion is similarly altered in children and adolescents who had never experienced depression but were at high risk of developing depression...
  9. ncbi request reprint Cognitive and family therapies for adolescent depression: treatment specificity, mediation, and moderation
    D J Kolko
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
    J Consult Clin Psychol 68:603-14. 2000
    ..As in adult studies, relatively few areas of treatment specificity or mediation were identified. The implications of these findings for clinical treatment and research in adolescent depression are discussed...
  10. ncbi request reprint Screen for Child Anxiety-Related Emotional Disorders (SCARED): convergent and divergent validity
    S Monga
    Child Psychiatry Department, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA
    Depress Anxiety 12:85-91. 2000
    ..05), thus demonstrating the discriminant validity of the SCARED. The SCARED is a reliable and valid screening tool for clinically referred children and adolescents with anxiety disorders...
  11. ncbi request reprint Atypical symptoms of depression in a sample of depressed child and adolescent outpatients
    D E Williamson
    Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, USA
    J Am Acad Child Adolesc Psychiatry 39:1253-9. 2000
    ..To examine the presence of symptoms of atypical depression among children and adolescents with a major depressive disorder (MDD)...
  12. ncbi request reprint Nocturnal ACTH, cortisol, growth hormone, and prolactin secretion in prepubertal depression
    M D De Bellis
    Department of Psychiatry, University of Pittsburgh, USA
    J Am Acad Child Adolesc Psychiatry 35:1130-8. 1996
    ..To examine nocturnal secretion of adrenocorticotropin, cortisol, growth hormone, and prolactin in 38 medically healthy children with prepubertal major depression compared with 28 medically and psychiatrically healthy control children...
  13. ncbi request reprint Subsyndromal depression in adolescents after a brief psychotherapy trial: course and outcome
    D A Brent
    Division of Child and Adolescent Psychiatry, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    J Affect Disord 63:51-8. 2001
    ..Since treatment trials of adolescent MDD often result in subsyndromal depression as the outcome, the long-term course of these youth would be useful to understand...
  14. ncbi request reprint Compliance with recommendations to remove firearms in families participating in a clinical trial for adolescent depression
    D A Brent
    Division of Child and Adolescent Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
    J Am Acad Child Adolesc Psychiatry 39:1220-6. 2000
    ..To assess the rate and correlates of compliance with clinicians' recommendations to remove firearms from the homes of depressed adolescents participating in a clinical trial...
  15. ncbi request reprint Relation between anxiety and depressive disorders in childhood and adolescence
    D A Axelson
    Child Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Depress Anxiety 14:67-78. 2001
    ..This component could contribute to the negative affective temperament that appears to be common in both pediatric depression and anxiety disorders...
  16. ncbi request reprint Fluoxetine in adolescents with major depression and an alcohol use disorder: an open-label trial
    J R Cornelius
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA 15213, USA
    Addict Behav 26:735-9. 2001
    ..The fluoxetine was well tolerated during the study. These data suggest promise for fluoxetine for decreasing both the depressive symptoms and the drinking of adolescents with comorbid major depression and an AUD...
  17. ncbi request reprint Neuropsychological study of frontal lobe function in psychotropic-naive children with obsessive-compulsive disorder
    S R Beers
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA 15213, USA
    Am J Psychiatry 156:777-9. 1999
    ..The authors' goal was to evaluate cognition in children with obsessive-compulsive disorder (OCD) early in their illness...
  18. ncbi request reprint Anxiety disorders in suicidal youth
    J Strauss
    Division of Child Psychiatry, University of Pittsburgh Medical Center, Pennsylvania, USA
    Can J Psychiatry 45:739-45. 2000
    ..To test the hypothesis that anxiety disorders are associated with suicidal ideation and suicide attempts in a child and adolescent sample referred to a clinic...
  19. ncbi request reprint Oculomotor response inhibition abnormalities in pediatric obsessive-compulsive disorder
    D R Rosenberg
    Department of Psychiatry, University of Pittsburgh Medical Center, PA, USA
    Arch Gen Psychiatry 54:831-8. 1997
    ....
  20. ncbi request reprint Frontostriatal measurement in treatment-naive children with obsessive-compulsive disorder
    D R Rosenberg
    Department of Psychiatry, University of Pittsburgh Medical Center, PA, USA
    Arch Gen Psychiatry 54:824-30. 1997
    ....
  21. ncbi request reprint Pediatric Bipolar Disorder: Do we know how to detect it?
    I Mendez
    Department of Pyschiatry, University of Pittsburg Medical Centre, Pennsylvania 15213, USA
    Actas Esp Psiquiatr 38:170-82. 2010
    ..To review the literature covering the epidemiology, clinical characteristics, longitudinal course, prognosis and clues for the assessment of the Pediatrics Bipolar Disorder (PBD)...
  22. pmc Reward-related decision-making in pediatric major depressive disorder: an fMRI study
    Erika E Forbes
    University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15218, USA
    J Child Psychol Psychiatry 47:1031-40. 2006
    ..Depression is postulated to involve decreased activity in reward-related affective systems...
  23. ncbi request reprint Course and outcome of bipolar spectrum disorder in children and adolescents: a review of the existing literature
    Boris Birmaher
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, PA 15213, USA
    Dev Psychopathol 18:1023-35. 2006
    ..Thus, early recognition and treatment of BP in children and adolescents is of utmost importance...
  24. ncbi request reprint Processing emotional facial expressions influences performance on a Go/NoGo task in pediatric anxiety and depression
    Cecile D Ladouceur
    Department of Psychiatry, School of Medicine, Western Psychiatric Institute and Clinic, University of Pittsburgh, PA 15213, USA
    J Child Psychol Psychiatry 47:1107-15. 2006
    ..This study investigated whether processing emotionally salient information such as emotional facial expressions influences the performance on a cognitive control task in pediatric anxiety and depression...
  25. ncbi request reprint Steady-state clinical pharmacokinetics of bupropion extended-release in youths
    W Burleson Daviss
    Western Psychiatric Institute and Clinic, University of Pittsburgh, USA
    J Am Acad Child Adolesc Psychiatry 45:1503-9. 2006
    ..To examine in children and adolescents the 24-hour, steady-state clinical pharmacokinetics of an extended-release (XL) formulation of bupropion (Wellbutrin XL)...
  26. ncbi request reprint Criterion validity of the Mood and Feelings Questionnaire for depressive episodes in clinic and non-clinic subjects
    W Burleson Daviss
    Western Psychiatric Institute and Clinic and the University of Pittsburgh, USA
    J Child Psychol Psychiatry 47:927-34. 2006
    ..The current study re-examines the criterion validity of child- and parent-versions of the Mood and Feelings Questionnaire (MFQ-C, MFQ-P) in a heterogeneous sample of children and adolescents from clinic and non-clinic sources...
  27. ncbi request reprint Psychopharmacologic treatment of pediatric major depressive disorder
    Khrista Boylan
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1200 Main St W Box 2000, Hamilton, ON L8N 3Z5, Canada
    Psychopharmacology (Berl) 191:27-38. 2007
    ..The role of pharmacotherapy in the treatment of major depressive disorder (MDD) in youth has received much attention in recent years due to concerns of efficacy and safety of the antidepressants for the treatment of MDD in youth...
  28. ncbi request reprint Child comorbidity, maternal mood disorder, and perceptions of family functioning among bipolar youth
    Christianne Esposito-Smythers
    Department of Psychiatry, Brown Medical School, Providence, RI 02912, USA
    J Am Acad Child Adolesc Psychiatry 45:955-64. 2006
    ..To examine the association between youth comorbid psychiatric disorders, maternal mood disorder, and perceptions of family cohesion and conflict among youth diagnosed with pediatric bipolar disorder (PBD)...
  29. ncbi request reprint Psychotic symptoms in pediatric bipolar disorder and family history of psychiatric illness
    Richard Rende
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI, USA
    J Affect Disord 96:127-31. 2006
    ..Few studies have examined the specificity and non-specificity in patterns of familial loading for presentation of psychotic symptoms in pediatric bipolar disorder (BP)...
  30. ncbi request reprint Acute antidepressant response and plasma levels of bupropion and metabolites in a pediatric-aged sample: an exploratory study
    W Burleson Daviss
    Western Psychiatric Institute and Clinic, Pittsburgh, PA, and the University of Pittsburgh, Pittsburgh, PA 15213, USA
    Ther Drug Monit 28:190-8. 2006
    ..009). These preliminary findings suggest that plasma levels of bupropion and metabolites, particularly hydroxybupropion, may predict acute antidepressant response in depressed youths taking bupropion SR...
  31. ncbi request reprint Child mania rating scale: development, reliability, and validity
    Mani N Pavuluri
    Department of Psychiatry, University of Illinois at Chicago, 60612, USA
    J Am Acad Child Adolesc Psychiatry 45:550-60. 2006
    ..To develop a reliable and valid parent-report screening instrument for mania, based on DSM-IVsymptoms...
  32. pmc Clinical course of children and adolescents with bipolar spectrum disorders
    Boris Birmaher
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, PA 15213, USA
    Arch Gen Psychiatry 63:175-83. 2006
    ..Despite the high morbidity associated with bipolar disorder (BP), few studies have prospectively studied the course of this illness in youth...
  33. pmc History of suicide attempts in pediatric bipolar disorder: factors associated with increased risk
    Tina R Goldstein
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Bipolar Disord 7:525-35. 2005
    ..Despite evidence indicating high morbidity associated with pediatric bipolar disorder (BP), little is known about the prevalence and clinical correlates of suicidal behavior among this population...
  34. pmc Childhood-onset bipolar disorder: Evidence for increased familial loading of psychiatric illness
    Richard Rende
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI, USA
    J Am Acad Child Adolesc Psychiatry 46:197-204. 2007
    ..To determine whether childhood-onset bipolar disorder (BP) is associated with an increased psychiatric family history compared with adolescent-onset BP...
  35. ncbi request reprint Childhood anxiety in a diverse primary care population: parent-child reports, ethnicity and SCARED factor structure
    Frances J Wren
    Division of Child and Adolescent Psychiatry, Stanford University School of Medicine, 401 Quarry Road, Standford, CA 94305 5719, USA
    J Am Acad Child Adolesc Psychiatry 46:332-40. 2007
    ....
  36. ncbi request reprint Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trials
    Jeffrey A Bridge
    Department of Pediatrics and Columbus Children s Research Institute, The Ohio State University, Columbus, USA
    JAMA 297:1683-96. 2007
    ..The US Food and Drug Administration (FDA) has issued warnings that use of antidepressant medications poses a small but significantly increased risk of suicidal ideation/suicide attempt for children and adolescents...
  37. pmc Familial transmission of suicidal behavior: factors mediating the relationship between childhood abuse and offspring suicide attempts
    Beth S Brodsky
    Department of Psychiatry, Columbia University New York State Psychiatric Institute, New York 10032, USA
    J Clin Psychiatry 69:584-96. 2008
    ..The current study investigates the relationship between reported childhood abuse and the familial transmission of suicidal behavior and other related risk factors...
  38. pmc Three-dimensional mapping of hippocampal anatomy in adolescents with bipolar disorder
    Carrie E Bearden
    Department of Psychiatry and Biobehavioral Sciences, UCLA, 300 Building Medical Plaza, Suite 2265, Los Angeles, CA 90095, USA
    J Am Acad Child Adolesc Psychiatry 47:515-25. 2008
    ..Using the same three-dimensional mapping methods, we sought to investigate whether a similar pattern exists in adolescents with bipolar disorder...
  39. pmc Subcortical gray matter volume abnormalities in healthy bipolar offspring: potential neuroanatomical risk marker for bipolar disorder?
    Cecile D Ladouceur
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 47:532-9. 2008
    ..The goal of this study was to examine whole-brain regional GM volume in healthy bipolar offspring (HBO) relative to age-matched controls to identify possible structural abnormalities that may be associated with risk for BD...
  40. pmc Mother-child interactions in depressed children and children at high risk and low risk for future depression
    Laura J Dietz
    Department of Psychiatry at the University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 47:574-82. 2008
    ..To compare mother-child interactions and parenting styles in families of children with major depressive disorder, youths at high risk for depression, and healthy controls...
  41. pmc Switching to another SSRI or to venlafaxine with or without cognitive behavioral therapy for adolescents with SSRI-resistant depression: the TORDIA randomized controlled trial
    David Brent
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    JAMA 299:901-13. 2008
    ..There are no data to guide clinicians on subsequent treatment strategy...
  42. doi request reprint Accuracy of brief and full forms of the Child Mania Rating Scale
    David B Henry
    Institute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60608, USA
    J Clin Psychol 64:368-81. 2008
    ..93 with 11 items from the full CMRS-P that were not used in constructing the brief version, and showed accuracy comparable to the full scale in differentiating BD from ADHD, and in discriminating among bipolar subtypes...
  43. pmc Pediatric bipolar disorder: validity, phenomenology, and recommendations for diagnosis
    Eric A Youngstrom
    Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 3270, USA
    Bipolar Disord 10:194-214. 2008
    ..To find, review, and critically evaluate evidence pertaining to the phenomenology of pediatric bipolar disorder and its validity as a diagnosis...
  44. pmc Objective sleep in pediatric anxiety disorders and major depressive disorder
    Erika E Forbes
    University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 47:148-55. 2008
    ..To examine objective and subjective sleep problems in early-onset anxiety and depression...
  45. pmc Pupillary reactivity to emotional information in child and adolescent depression: links to clinical and ecological measures
    Jennifer S Silk
    Western Psychiatric Institute and Clinic, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Am J Psychiatry 164:1873-80. 2007
    ....
  46. pmc Caffeine consumption, sleep, and affect in the natural environments of depressed youth and healthy controls
    Diana J Whalen
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    J Pediatr Psychol 33:358-67. 2008
    ..We examined caffeine use and its relation to sleep and affect in youth's natural environments...
  47. pmc Familial pathways to early-onset suicidal behavior: familial and individual antecedents of suicidal behavior
    Nadine M Melhem
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Psychiatry 164:1364-70. 2007
    ..The authors sought to identify clinical predictors of new-onset suicidal behavior in children of parents with a history of mood disorder and suicidal behavior...
  48. pmc Aggression, hostility, and irritability in children at risk for bipolar disorder
    Tiffany R Farchione
    Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Bipolar Disord 9:496-503. 2007
    ..To assess aggression, irritability and hostility in children at risk for bipolar disorder (BP)...
  49. pmc Dialectical behavior therapy for adolescents with bipolar disorder: a 1-year open trial
    Tina R Goldstein
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 46:820-30. 2007
    ..To describe an adapted version of dialectical behavior therapy for adolescents with bipolar disorder...
  50. ncbi request reprint Increased error-related negativity (ERN) in childhood anxiety disorders: ERP and source localization
    Cecile D Ladouceur
    Department of Psychiatry, School of Medicine, Western Psychiatric Institute and Clinic, University of Pittsburgh, PA 15213, USA
    J Child Psychol Psychiatry 47:1073-82. 2006
    ....
  51. ncbi request reprint Fluoxetine for the treatment of childhood anxiety disorders: open-label, long-term extension to a controlled trial
    Duncan B Clark
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 44:1263-70. 2005
    ..To assess the efficacy of fluoxetine for the long-term treatment of children and adolescents with anxiety disorders, including generalized anxiety disorder, separation anxiety disorder, and/or social phobia...
  52. ncbi request reprint Psychosocial functioning in youths at high risk to develop major depressive disorder
    Boris Birmaher
    Department of Child Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, Pittsburgh PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 43:839-46. 2004
    ..To compare the psychosocial functioning of children and adolescents at high risk of major depressive disorder with youths with acute major depressive disorder and healthy controls...
  53. ncbi request reprint First episode of depression in children at low and high familial risk for depression
    Douglas E Williamson
    Department of Child and Adolescent Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 43:291-7. 2004
    ..To examine the development of first-onset major depressive disorder (MDD) in children at high and low familial risk for depression in a prospective study...
  54. ncbi request reprint Recurrent abdominal pain, anxiety, and depression in primary care
    John V Campo
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Pediatrics 113:817-24. 2004
    ..Our aim was to determine whether RAP is associated with psychiatric symptoms and disorders, anxious temperament, and functional impairment in pediatric primary care...
  55. ncbi request reprint Lifetime history of sexual abuse, clinical presentation, and outcome in a clinical trial for adolescent depression
    Rémy P Barbe
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Clin Psychiatry 65:77-83. 2004
    ..To investigate the impact of sexual abuse on clinical presentation and treatment outcome in depressed adolescents...
  56. ncbi request reprint Clinical presentation and course of depression in youth: does onset in childhood differ from onset in adolescence?
    Boris Birmaher
    University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 43:63-70. 2004
    ..To simultaneously and prospectively compare the clinical presentation, course, and parental psychiatric history between children and adolescents with major depressive disorder...
  57. ncbi request reprint Measuring mood and complex behavior in natural environments: use of ecological momentary assessment in pediatric affective disorders
    David A Axelson
    Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
    J Child Adolesc Psychopharmacol 13:253-66. 2003
    ..Potential applications of the EMA methodology to the study of neurobehavioral systems and the pathophysiology of pediatric affective disorders are discussed...
  58. ncbi request reprint Major depressive disorder in adolescents exposed to a friend's suicide
    Jeffrey A Bridge
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 42:1294-300. 2003
    ....
  59. ncbi request reprint Gastrointestinal distress to serotonergic challenge: a risk marker for emotional disorder?
    John V Campo
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 42:1221-6. 2003
    ..The authors' aim was to determine whether inadvertent gastrointestinal (GI) distress to serotonergic challenge predicted future major depressive and/or anxiety disorders in exposed children...
  60. ncbi request reprint The stressful life events schedule for children and adolescents: development and validation
    Douglas E Williamson
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Psychiatry Res 119:225-41. 2003
    ..48). The results of this study indicate that the SLES has good psychometric properties. The SLES is a useful, cost-effective tool for assessing stressful life events in children and adolescents...
  61. ncbi request reprint Peripubertal suicide attempts in offspring of suicide attempters with siblings concordant for suicidal behavior
    David A Brent
    Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Am J Psychiatry 160:1486-93. 2003
    ....
  62. ncbi request reprint Familial pathways to early-onset suicide attempt: risk for suicidal behavior in offspring of mood-disordered suicide attempters
    David A Brent
    Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Arch Gen Psychiatry 59:801-7. 2002
    ..Although adoption, twin, and family studies have shown that suicidal behavior is familial, the risk factors for familial transmission from parent to child remain unclear...
  63. ncbi request reprint Heterogeneity in EEG sleep findings in adolescent depression: unipolar versus bipolar clinical course
    Uma Rao
    Department of Psychiatry and Biobehavioral Sciences, UCLA, Los Angeles, CA 90024 1759, USA
    J Affect Disord 70:273-80. 2002
    ..This investigation was designed to assess whether some of the observed variability is related to undifferentiated unipolar and bipolar disorders in a sample that was reported previously...
  64. ncbi request reprint Is bipolar disorder specifically associated with panic disorder in youths?
    Boris Birmaher
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA 15213, USA
    J Clin Psychiatry 63:414-9. 2002
    ..To replicate previous findings of high rates of bipolar disorder (BPD) in patients with panic disorder (PD) and determine if youths with both PD and BPD have more severe illness...
  65. ncbi request reprint Cross-sectional study of abnormal amygdala development in adolescents and young adults with bipolar disorder
    Barbara K Chen
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Biol Psychiatry 56:399-405. 2004
    ....
  66. ncbi request reprint Phenomenology of panic disorder in youth
    Rasim Somer Diler
    Division of Child Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
    Depress Anxiety 20:39-43. 2004
    ..Subjects with both panic and non-panic anxiety disorders were more likely to have comorbid major depression and conduct disorders than those with other non-anxiety disorders...
  67. ncbi request reprint Citalopram treatment of pediatric recurrent abdominal pain and comorbid internalizing disorders: an exploratory study
    John V Campo
    Department of Pyschiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 43:1234-42. 2004
    ..To assess the potential efficacy, tolerability, and safety of citalopram in the treatment of functional pediatric recurrent abdominal pain and comorbid internalizing disorders...
  68. ncbi request reprint Emergent suicidality in a clinical psychotherapy trial for adolescent depression
    Jeffrey A Bridge
    Western Psychiatric Institute and Clinic, Child and Adolescent Psychiatry, 3811 O Hara St, BFT 311, Pittsburgh, PA 15213 2592, USA
    Am J Psychiatry 162:2173-5. 2005
    ..The authors' goal was to examine the incidence and predictors of emergent suicidality that occurred during a clinical trial of psychotherapy for adolescent depression...
  69. ncbi request reprint Subjective sleep complaints in pediatric depression: a controlled study and comparison with EEG measures of sleep and waking
    Michele A Bertocci
    University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 44:1158-66. 2005
    ..This article examines subjective sleep reports of children with MDD and healthy controls focusing on comparing subjective and objective sleep measures...
  70. ncbi request reprint Stressful life events in anxious and depressed children
    Douglas E Williamson
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA Williamson
    J Child Adolesc Psychopharmacol 15:571-80. 2005
    ..The aim of this study was to examine the occurrence of stressful life events in anxious and depressed children...
  71. pmc Peri-sleep-onset cortisol levels in children and adolescents with affective disorders
    Erika E Forbes
    Department of Psychiatry, University of Pittsburgh, PA 15213, USA
    Biol Psychiatry 59:24-30. 2006
    ..Evidence also indicates that pubertal development may influence the expression of HPA dysregulation. We hypothesized that adolescents with depression and youth with anxiety disorders exhibit elevated peri-sleep-onset cortisol...
  72. ncbi request reprint Acute phase and five-year follow-up study of fluoxetine in adolescents with major depression and a comorbid substance use disorder: a review
    Jack R Cornelius
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 30:1824-33. 2005
    ..However, the long-term clinical course for the Major Depression of that comorbid adolescent population is surprisingly poor...
  73. ncbi request reprint Altered emotional processing in pediatric anxiety, depression, and comorbid anxiety-depression
    Cecile D Ladouceur
    Department of Psychiatry, School of Medicine, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Abnorm Child Psychol 33:165-77. 2005
    ..Further, research is needed to replicate this study and delineate underlying neural mechanisms...
  74. ncbi request reprint Clinical differences between suicidal and nonsuicidal depressed children and adolescents
    Rémy P Barbe
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Clin Psychiatry 66:492-8. 2005
    ..To examine the clinical symptoms and comorbid psychiatric disorders of depressed children and adolescents with and without clinically significant suicidal ideation...
  75. ncbi request reprint Platelet serotonin reuptake inhibition and response to SSRIs in depressed adolescents
    David A Axelson
    Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Am J Psychiatry 162:802-4. 2005
    ..The authors examined platelet serotonin reuptake inhibition and response to selective serotonin reuptake inhibitor (SSRI) treatment in depressed adolescents...
  76. ncbi request reprint Steady-state pharmacokinetics of bupropion SR in juvenile patients
    W Burleson Daviss
    Western Psychiatric Institute and Clinic, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 44:349-57. 2005
    ..To examine the steady-state pharmacokinetic properties of bupropion sustained release (SR) and their potential developmental differences in youths...
  77. ncbi request reprint Posttraumatic stress disorder comorbid with major depression: factors mediating the association with suicidal behavior
    Maria Oquendo
    Department of Neuroscience, New York State Psychiatric Institute Columbia University, 1051 Riverside Dr, Unit 42, New York, NY 10032, USA
    Am J Psychiatry 162:560-6. 2005
    ....
  78. ncbi request reprint Clinical characteristics of depressive symptoms in children and adolescents with major depressive disorder
    Ozgur Yorbik
    Gulhane Military Medical Faculty, The Department of Child and Adolescent Psychiatry, Ankara, Turkey
    J Clin Psychiatry 65:1654-9; quiz 1760-1. 2004
    ..Very few studies have compared the symptoms of major depressive disorder (MDD) and rates of comorbid psychiatric disorders between depressed children and adolescents. The aim of this study was to reproduce and extend these findings...
  79. ncbi request reprint Screening for childhood anxiety symptoms in primary care: integrating child and parent reports
    Frances J Wren
    Division of Child and Adolescent Psychiatry, Stanford University School of Medicine, CA 94305 5719, USA
    J Am Acad Child Adolesc Psychiatry 43:1364-71. 2004
    ..It also explores the use in primary care of the Screen for Child Anxiety Related Emotional Disorders (SCARED) and the Pediatric Symptom Checklist (PSC-17)...
  80. ncbi request reprint Familial transmission of mood disorders: convergence and divergence with transmission of suicidal behavior
    David A Brent
    Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 43:1259-66. 2004
    ..In this study, the authors examine the factors associated with the familial transmission of these two related conditions to learn which are shared or unique risk factors for familial transmission...
  81. ncbi request reprint Superior temporal gyrus volumes in pediatric generalized anxiety disorder
    Michael D De Bellis
    University of Pittsburgh Medical Center, Developmental Traumatology Program Developmental Family Health Clinic and Neuroimaging Laboratory, Western Psychiatric Institute and Clinic, Rm 392, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Biol Psychiatry 51:553-62. 2002
    ..Larger amygdala volumes were previously reported in pediatric GAD; however, the brain regions involved in social intelligence were not examined in this pilot study...