Jon Paul Bingham
Affiliation: University of Hawaii
Thapa P, Zhang R, Menon V, Bingham J. Native chemical ligation: a boon to peptide chemistry. Molecules. 2014;19:14461-83 pubmed publisher
..Here we illustrate and explore the historical and current nature of peptide ligation, providing a clear indication to the possibilities and use of these novel methods to take peptides outside their typically defined boundaries. ..
Halford Z, Yu P, Likeman R, Hawley Molloy J, Thomas C, Bingham J. Cone shell envenomation: epidemiology, pharmacology and medical care. Diving Hyperb Med. 2015;45:200-7 pubmed
..We have also made available a brief background to the biochemistry and pharmacology of Conus venoms to highlight their complex nature. ..
Thapa P, Cabalteja C, Philips E, Espiritu M, Peigneur S, Mille B, et al
. t-boc synthesis of huwentoxin-i through native chemical ligation incorporating a trifluoromethanesulfonic acid cleavage strategy. Biopolymers. 2016;106:737-45 pubmed publisher
..2016 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 106: 737-745, 2016. ..
Zhang R, Thapa P, Espiritu M, Menon V, Bingham J. From nature to creation: Going around in circles, the art of peptide cyclization. Bioorg Med Chem. 2018;26:1135-1150 pubmed publisher
..These efforts have circumvented otherwise impossible hurdles in their manipulation and production that are only now advancing cyclic peptides/cyclotides as research probes and future pharmaceutical templates. ..