Research Topics
| Devin K BinderSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Surgical treatment of occipital lobe epilepsyDevin K Binder
Department of Neurological Surgery, University of California, Irvine, Orange, California 92868 3298, USA
J Neurosurg 109:57-69. 2008..Preoperative findings, surgical strategies, histopathological bases, and postoperative outcomes for OLE remain to be elucidated...
Neurotrophins in the dentate gyrusDevin K Binder
Department of Neurological Surgery, University of California, Irvine, CA 92868, USA
Prog Brain Res 163:371-97. 2007..Modulation of neurotrophin action holds significant potential for novel therapies for a variety of neurological and psychiatric disorders...- Friedrich-Christian Rosenthal: surgeon and anatomistDevin K Binder
Department of Neurological Surgery, University of California, Irvine, Irvine, California, USA
Neurosurgery 59:1328-33. 2006..After an itinerant academic, military, and professional career, he died of tuberculosis in Greifswald on December 5, 1829, working to the end on an unfinished treatise on the anatomy of the brain and cranial nerves... - The seminal contributions of Johann-Christian Reil to anatomy, physiology, and psychiatryDevin K Binder
Department of Neurological Surgery, University of California, Irvine, Orange, California 92868 3298, USA
Neurosurgery 61:1091-6; discussion 1096. 2007..quot; In addition, he was a private confidante and physician to Johann Wolfgang von Goethe. Reil died in 1813 from typhus while treating soldiers wounded in the Battle of the Nations at Leipzig during the Napoleonic Wars... - Surgical treatment of parietal lobe epilepsyDevin K Binder
Department of Neurological Surgery, University of California, Irvine, California, USA
J Neurosurg 110:1170-8. 2009..Preoperative findings, surgical strategies, pathological bases, and postoperative outcomes for PLE remain to be elucidated... - Characteristics of auras in patients undergoing temporal lobectomyDevin K Binder
Department of Neurological Surgery, University of California, Irvine, 101 The City Drive South, Building 56, Suite 400, ZOT 5397 Orange, California 92868 3298, USA
J Neurosurg 111:1283-9. 2009..Prior studies suggest that aura semiology may have localizing value. However, temporal lobe aura characteristics and response to surgery have not been studied in large patient series... - Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channelsDevin K Binder
Department of Neurological Surgery, University of California, San Francisco, 94110, USA
Glia 53:631-6. 2006..5 +/- 0.1 and 6.6 +/- 0.7 s, respectively). These results implicate AQP4 in the expression and termination of seizure activity and support the hypothesis that AQP4 is coupled to potassium homeostasis in vivo... - Enhanced macromolecular diffusion in brain extracellular space in mouse models of vasogenic edema measured by cortical surface photobleachingMarios C Papadopoulos
Department of Medicine and Physiology, University of California, San Francisco, California 94143-0521, USA
FASEB J 19:425-7. 2005..Our data provide in vivo evidence for enhanced ECS diffusion in vasogenic brain edema, yet greatly slowed diffusion in cytotoxic edema and in and around tumors... - Three distinct roles of aquaporin-4 in brain function revealed by knockout miceA S Verkman
Departments of Medicine and Physiology, Cardiovascular Research Institute, 1246 Health Sciences East Tower, Box 0521, University of California, San Francisco, CA 94143 0521, USA
Biochim Biophys Acta 1758:1085-93. 2006..Based on these findings, we propose modulation of AQP4 expression or function as a novel therapeutic strategy for a variety of cerebral disorders including stroke, tumor, infection, hydrocephalus, epilepsy, and traumatic brain injury... 
Decreased expression of the glial water channel aquaporin-4 in the intrahippocampal kainic acid model of epileptogenesisDarrin J Lee
Department of Neurological Surgery, University of California, Davis, CA, USA
Exp Neurol 235:246-55. 2012..Restoration of astrocytic water and ion homeostasis may represent a novel therapeutic strategy...- In vivo measurement of brain extracellular space diffusion by cortical surface photobleachingDevin K Binder
Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California 94143 0521, USA
J Neurosci 24:8049-56. 2004.... - Functional changes in astroglial cells in epilepsyDevin K Binder
Department of Neurological Surgery, University of California, Irvine, Irvine, California, USA
Glia 54:358-68. 2006.... - Improved survival following cerebral edema using a novel hollow fiber-hydrogel deviceDevin W McBride
B2K Group Biotransport and Bioreaction Kinetics Group, Department of Bioengineering and the Center for Bioengineering Research, University of California, Riverside, California 92521, USA
J Neurosurg 116:1389-94. 2012..Current therapies of cerebral edema are often ineffective in treating severe edema. Here, the authors develop a hollow fiber-hydrogel device (HFHD) for direct surface contact-based treatment of severe cerebral edema... - Protective role of aquaporin-4 water channels after contusion spinal cord injuryAtsushi Kimura
Department of Neurological Surgery, University of California, Irvine, CA, USA
Ann Neurol 67:794-801. 2010..However, the mechanisms that control edema and the extent to which edema impacts outcome after SCI are not well elucidated... - Early optical detection of cerebral edema in vivoAmandip S Gill
Department of Neurological Surgery, University of California, Irvine, California, USA
J Neurosurg 114:470-7. 2011..The authors report the development of 2 distinct minimally invasive fiberoptic near-infrared (NIR) techniques able to directly detect early cerebral edema... - Transcortical cooling inhibits hippocampal-kindled seizures in the ratJustin M Burton
Department of Neurological Surgery, Washington University, St. Louis, Missouri 63110, USA
Epilepsia 46:1881-7. 2005..These findings have important implications for the potential use of implantable cooling devices in humans with refractory epilepsies in or near eloquent cortex or dominant hippocampal formations... - Altered white matter integrity in temporal lobe epilepsy: association with cognitive and clinical profilesJeffrey D Riley
Department of Neurology, University of California, Irvine, CA 92868, USA
Epilepsia 51:536-45. 2010..However, limited data exist regarding the extent of white matter tract abnormalities, cognitive effects of these abnormalities, and relationship to clinical factors. The current study examined these issues in subjects with chronic TLE... - Brain-derived neurotrophic factorDevin K Binder
Department of Neurological Surgery, M779 Moffitt Hospital, Box 0112, University of California, San Francisco, CA 94143 0112, USA
Growth Factors 22:123-31. 2004.... - Aquaporin-4-dependent edema clearance following status epilepticusDarrin J Lee
Department of Neurological Surgery, University of California, Davis, CA, United States
Epilepsy Res 98:264-8. 2012..These results have implications for the mechanisms of edema formation and clearance following intense seizure activity... - Hippocampus minor, calcar avis, and the Huxley-Owen debateChristopher M Owen
Department of Neurological Surgery, University of California, Irvine, California 92868 3298, USA
Neurosurgery 65:1098-104; discussion 1104-5. 2009..Thus, this relatively obscure neuroanatomic landmark served as a pivotal point of contention in the most popularized and acrimonious evolutionary debate of the 19th century... - Gamma Knife radiosurgery for brain metastases from primary breast cancerNorbert Kased
Department of Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, CA 94143 0226, USA
Int J Radiat Oncol Biol Phys 75:1132-40. 2009..The relative roles of stereotactic radiosurgery (SRS) vs. whole brain radiotherapy (WBRT) in the treatment of patients with brain metastases from breast cancer remain undefined. In this study, we reviewed our experience with these patients... - The maestro don Gonzalo Rodríguez-LaforaAnish S Nanduri
Department of Neurological Surgery, University of California, Irvine, California 92868 3298, USA
Epilepsia 49:943-7. 2008..quot; Throughout his intellectual endeavors, Lafora manifested a singular purpose and intensity and a burning devotion to scientific honesty... - Cerebral salt wasting and elevated brain natriuretic peptide levels after traumatic brain injury: 2 case reportsDaniel C Lu
Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94107, USA
Surg Neurol 69:226-9. 2008..Here, we describe 2 cases of CSW in TBI patients with elevated BNP levels. This phenomenon has not been previously described... - Multispectral imaging of tissue absorption and scattering using spatial frequency domain imaging and a computed-tomography imaging spectrometerJessie R Weber
University of California, Irvine, Beckman Laser Institute and Medical Clinic, 1002 Health Sciences Road East, Irvine, California, 92612, USA
J Biomed Opt 16:011015. 2011..The SFDI-CTIS platform was applied to a mouse model of brain injury in order to demonstrate the utility of this approach in characterizing spatially and spectrally varying tissue optical properties... - Robert Bentley Todd's contribution to cell theory and the neuron doctrineDevin K Binder
Center for Glial Neuronal Interactions, Division of Biomedical Sciences, University of California, Riverside, CA, USA
J Hist Neurosci 20:123-34. 2011..Influenced by his contemporary, Faraday, Todd was also the first to develop the functional concept of dynamic polarization ("nervous polarity") to explain nerve cell conduction... - Tumor-associated epilepsyKiran F Rajneesh
Department of Neurological Surgery, University of California, Irvine, California, USA
Neurosurg Focus 27:E4. 2009..Further understanding of the mechanisms of tumor-associated epilepsy may lead to new types of treatments targeted at perilesional tissue alterations... - William P. van Wagenen and the first corpus callosotomies for epilepsyMarlon S Mathews
Department of Neurological Surgery, University of California, Irvine, Orange, CA 92868, USA
J Neurosurg 108:608-13. 2008..Sperry in 1981. These contributions firmly establish William P. van Wagenen as one of the founding pioneers in the surgical treatment of patients with epilepsy... - Expression of the aquaporin-1 water channel in human glial tumorsKotaro Oshio
Department of Neurological Surgery, University of California, San Francisco, San Francisco, California, USA
Neurosurgery 56:375-81; discussion 375-81. 2005.... - The madness of Dionysus: a neurosurgical perspective on Friedrich NietzscheChristopher M Owen
Department of Neurological Surgery, University of California, Irvine, Irvine, California, USA
Neurosurgery 61:626-31; discussion 631-2. 2007..To examine the possibility that an intracranial mass may have been the etiology of the headaches and neurological findings of the philosopher Friedrich Nietzsche (1844-1900) and the cause of his ultimate mental collapse in 1889... - Aquaporin-4 and epilepsyDevin K Binder
Center for Glial Neuronal Interactions, Division of Biomedical Sciences, University of California, Riverside, California 92521 0121, USA
Glia 60:1203-14. 2012..While many questions remain unanswered, the available data indicate that AQP4 and its molecular partners may represent important new therapeutic targets... - Local cortical hypoperfusion imaged with CT perfusion during postictal Todd's paresisMarlon S Mathews
Department of Neurological Surgery, University of California, Irvine, CA, USA
Neuroradiology 50:397-401. 2008..However, it is unclear whether the pathophysiology of Todd's paralysis is related to alterations in cerebral perfusion. We report CT perfusion findings in a patient presenting with postictal aphasia and right hemiparesis... - Multiple root avulsions from the brachial plexus. Case illustrationDevin K Binder
Department of Neurological Surgery, University of California, San Francisco, California 94143-0112, USA
Neurosurg Focus 19:E9. 2005 - Isolated amygdala neurocysticercosis in a patient presenting with déjà vu and olfactory auras. Case reportDarrin J Lee
Department of Neurological Surgery, University of California, Irvine, CA, USA
J Neurosurg Pediatr 3:538-41. 2009..Uniquely, the case demonstrates that both olfactory and déjà vu auras can emanate from the amygdala... - Aquaporin-4-dependent K(+) and water transport modeled in brain extracellular space following neuroexcitationByung Ju Jin
Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
J Gen Physiol 141:119-32. 2013.... - In vivo detection of cortical optical changes associated with seizure activity with optical coherence tomographyMelissa M Eberle
Department of Bioengineering, University of California, Riverside, 900 University Ave, Riverside, CA 92521, USA
Biomed Opt Express 3:2700-6. 2012..These results indicate the feasibility of minimally-invasive optical detection of seizures with OCT... - Increased seizure threshold in mice lacking aquaporin-4 water channelsDevin K Binder
Department of Neurological Surgery, University of California, 505 Parnassus Ave, Box 0112, San Francisco, CA 94143, USA
Neuroreport 15:259-62. 2004..These results suggest that glial water channels may modulate brain excitability and the initiation and generalization of seizure activity... - Primary brachial plexus tumors: imaging, surgical, and pathological findings in 25 patientsDevin K Binder
Department of Neurological Surgery, University of California, San Francisco, California 94143-0112, USA
Neurosurg Focus 16:E11. 2004..CONCLUSIONS: Primary tumors arising in the brachial plexus are rare. Careful workup, surgical technique, and attention to pathological diagnosis optimize management... - The role of BDNF in epilepsy and other diseases of the mature nervous systemDevin K Binder
Department of Neurological Surgery, University of California at San Francisco, Moffitt Hospital, USA
Adv Exp Med Biol 548:34-56. 2004..Further study of the cellular and molecular mechanisms by which BDNF influences cell survival and excitability will likely provide novel concepts and targets for the treatment of diverse CNS diseases... - A history of Todd and his paralysisDevin K Binder
Department of Neurological Surgery, M779 Moffitt Hospital, Box 0112, University of California San Francisco, San Francisco, CA 94143 0112, USA
Neurosurgery 54:480-6; discussion 486-7. 2004..quot;.. - Hemorrhagic complications of microelectrode-guided deep brain stimulationDevin K Binder
Department of Neurological Surgery, University of California, San Francisco, CA 94143 0112, USA
Stereotact Funct Neurosurg 80:28-31. 2003..We report the incidence of hemorrhage in a large series of DBS implants into the subthalamic nucleus (STN), thalamus (VIM) and internal globus pallidus (GPi)... - Intrathecal saline infusion in the treatment of obtundation associated with spontaneous intracranial hypotension: technical case reportDevin K Binder
Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143 0112, USA
Neurosurgery 51:830-6; discussion 836-7. 2002..Spontaneous intracranial hypotension is an increasingly recognized cause of postural headache. However, appropriate management of obtundation caused by intracranial hypotension is not well defined... - Transcranial motor evoked potential recording in a case of Kernohan's notch syndrome: case reportDevin K Binder
Department of Neurological Surgery, M779 Moffitt Hospital, Box 0112, University of California San Francisco, San Francisco, CA 94143 0112, USA
Neurosurgery 54:999-1002; discussion 1002-3. 2004..Here, we demonstrate a case in which clinical, radiological, and electrophysiological findings were used together to define this syndrome... - Transsylvian functional hemispherectomyDevin K Binder
Department of Neurosurgery, University of Bonn Medical Center, Sigmund-Freud-Str. 25, 53105, Bonn, Germany
Childs Nerv Syst 22:960-6. 2006..The efficacy of functional hemispherectomy procedures in achieving seizure freedom appears to be at least as good compared to resective procedures. The long-term complication rate will require longer follow-up times... - Wilder Penfield, PÃo del RÃo-Hortega, and the discovery of oligodendrogliaAmandip S Gill
Neurosurgery 60:940-8; discussion 940-8. 2007..While working with RÃo-Hortega, his report on oligodendroglia was critical to advancing the characterization of this important class of glial cells...
Research Grants
- Aquaporin Water Transport, Extracellular Space, and EpilepsyDevin Binder; Fiscal Year: 2007..In addition, development of novel optical techniques for seizure detection based on changes in the brain that occur just prior to seizure onset will have a direct clinical impact on the many patients whose seizures remain uncontrolled. ..