R M Bilder

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Executive control: balancing stability and flexibility via the duality of evolutionary neuroanatomical trends
    Robert M Bilder
    Department of Psychiatry and Biobehavioral Sciences, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA
    Dialogues Clin Neurosci 14:39-47. 2012
  2. ncbi request reprint The catechol-O-methyltransferase polymorphism: relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes
    Robert M Bilder
    Department of Psychiatry, David Geffen School of Medicine and Psychology, UCLA Neuropsychiatric Institute, University of California at Los Angeles, Los Angeles, CA, USA
    Neuropsychopharmacology 29:1943-61. 2004
  3. ncbi request reprint Cognitive development in schizophrenia: follow-back from the first episode
    Robert M Bilder
    Semel Institute for Neuroscience at UCLA, Los Angeles, CA, USA
    J Clin Exp Neuropsychol 28:270-82. 2006
  4. pmc The genetics of cognitive impairment in schizophrenia: a phenomic perspective
    Robert M Bilder
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Trends Cogn Sci 15:428-35. 2011
  5. pmc Phenomics: building scaffolds for biological hypotheses in the post-genomic era
    Robert M Bilder
    Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, California 90095, USA
    Biol Psychiatry 63:439-40. 2008
  6. pmc Phenomics: the systematic study of phenotypes on a genome-wide scale
    R M Bilder
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at University of California, Los Angeles, CA, USA
    Neuroscience 164:30-42. 2009
  7. pmc Cognitive ontologies for neuropsychiatric phenomics research
    Robert M Bilder
    Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, CA 90095, USA
    Cogn Neuropsychiatry 14:419-50. 2009
  8. pmc Neuropsychology 3.0: evidence-based science and practice
    Robert M Bilder
    Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, California 90095, USA
    J Int Neuropsychol Soc 17:7-13. 2011
  9. pmc Challenges in phenotype definition in the whole-genome era: multivariate models of memory and intelligence
    F W Sabb
    Consortium for Neuropsychiatric Phenomics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA
    Neuroscience 164:88-107. 2009
  10. ncbi request reprint Abnormal gyral complexity in first-episode schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90095 1769, USA
    Biol Psychiatry 55:859-67. 2004

Detail Information

Publications66

  1. pmc Executive control: balancing stability and flexibility via the duality of evolutionary neuroanatomical trends
    Robert M Bilder
    Department of Psychiatry and Biobehavioral Sciences, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA
    Dialogues Clin Neurosci 14:39-47. 2012
    ....
  2. ncbi request reprint The catechol-O-methyltransferase polymorphism: relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes
    Robert M Bilder
    Department of Psychiatry, David Geffen School of Medicine and Psychology, UCLA Neuropsychiatric Institute, University of California at Los Angeles, Los Angeles, CA, USA
    Neuropsychopharmacology 29:1943-61. 2004
    ....
  3. ncbi request reprint Cognitive development in schizophrenia: follow-back from the first episode
    Robert M Bilder
    Semel Institute for Neuroscience at UCLA, Los Angeles, CA, USA
    J Clin Exp Neuropsychol 28:270-82. 2006
    ..These observations may help advance concepts of premorbid cognitive ability in the schizophrenia syndrome and constrain models of pathophysiology...
  4. pmc The genetics of cognitive impairment in schizophrenia: a phenomic perspective
    Robert M Bilder
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Trends Cogn Sci 15:428-35. 2011
    ....
  5. pmc Phenomics: building scaffolds for biological hypotheses in the post-genomic era
    Robert M Bilder
    Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, California 90095, USA
    Biol Psychiatry 63:439-40. 2008
  6. pmc Phenomics: the systematic study of phenotypes on a genome-wide scale
    R M Bilder
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at University of California, Los Angeles, CA, USA
    Neuroscience 164:30-42. 2009
    ....
  7. pmc Cognitive ontologies for neuropsychiatric phenomics research
    Robert M Bilder
    Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, CA 90095, USA
    Cogn Neuropsychiatry 14:419-50. 2009
    ..It is hoped that these tools will help formalise inference about cognitive concepts in behavioural and neuroimaging studies, and facilitate discovery of the genetic bases of both healthy cognition and cognitive disorders...
  8. pmc Neuropsychology 3.0: evidence-based science and practice
    Robert M Bilder
    Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, California 90095, USA
    J Int Neuropsychol Soc 17:7-13. 2011
    ..This article considers these opportunities, highlights selected obstacles, and offers suggestions for stepwise progress toward these goals...
  9. pmc Challenges in phenotype definition in the whole-genome era: multivariate models of memory and intelligence
    F W Sabb
    Consortium for Neuropsychiatric Phenomics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA
    Neuroscience 164:88-107. 2009
    ..These results are available online through the http://www.phenowiki.org database. Further work needs to be done in order to provide consensus-building applications for the broadly defined constructs used in neuroscience research...
  10. ncbi request reprint Abnormal gyral complexity in first-episode schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90095 1769, USA
    Biol Psychiatry 55:859-67. 2004
    ..Few studies, however, have investigated gyral complexity in schizophrenia...
  11. ncbi request reprint Cortical thinning in cingulate and occipital cortices in first episode schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California, USA
    Biol Psychiatry 58:32-40. 2005
    ....
  12. pmc Mapping the relationship between cortical convolution and intelligence: effects of gender
    Eileen Luders
    Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, USA
    Cereb Cortex 18:2019-26. 2008
    ..This might lead to the development of sexually dimorphic information processing strategies and affect the relationship between intelligence and cortical convolution...
  13. ncbi request reprint Impairments in perceptual competency and maintenance on a visual delayed match-to-sample test in first-episode schizophrenia
    Todd Lencz
    Department of Psychiatry, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
    Arch Gen Psychiatry 60:238-43. 2003
    ..It was hypothesized that patients in the first episode of schizophrenia would exhibit dissociable deficits in both WM domains...
  14. doi request reprint Selective corticostriatal dysfunction in schizophrenia: examination of motor and cognitive skill learning
    Karin Foerde
    Department of Psychology, University of California Los Angeles, Los Angeles, CA, USA
    Neuropsychology 22:100-9. 2008
    ..In contrast, patients were not impaired at learning on the SRT relative to controls, suggesting that patients with schizophrenia may have dysfunction in a specific corticostriatal subcircuit...
  15. ncbi request reprint Regional specificity of hippocampal volume reductions in first-episode schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1769, USA
    Neuroimage 21:1563-75. 2004
    ..Targeting regional hippocampal abnormalities may help dissociate schizophrenia patients from other groups exhibiting global hippocampal volume changes, and better focus systems-level pathophysiological hypotheses...
  16. ncbi request reprint Relationships between IQ and regional cortical gray matter thickness in healthy adults
    Katherine L Narr
    Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at the University of California, Los Angeles UCLA, Los Angeles, CA 90095 7334, USA
    Cereb Cortex 17:2163-71. 2007
    ..Sex moderates regional relationships that may index dimorphisms in cognitive abilities, overall processing strategies, or differences in structural organization...
  17. pmc The Cognitive Assessment Interview (CAI): development and validation of an empirically derived, brief interview-based measure of cognition
    Joseph Ventura
    Semel Institute for Neuroscience and Human Behavior, Geffen School of Medicine at UCLA, United States
    Schizophr Res 121:24-31. 2010
    ....
  18. pmc Asymmetries of cortical shape: Effects of handedness, sex and schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Department of Neurology, Division of Brain Mapping, UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095 1769, USA
    Neuroimage 34:939-48. 2007
    ....
  19. ncbi request reprint Working memory effects on semantic processing: priming differences in pars orbitalis
    Fred W Sabb
    Semel Institute for Neuroscience and Human Behavior, Department of Psychiatry, University of California, Los Angeles 760 Westwood Plaza, Los Angeles, CA 90095, USA
    Neuroimage 37:311-22. 2007
    ..fMRI signal changes in dorsolateral prefrontal cortex were negatively correlated with signal changes in pars orbitalis. The findings suggest that controlled semantic processing and working memory share neural system resources...
  20. pmc DTNBP1 is associated with imaging phenotypes in schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging and Ahmanson Lovelace Brain Mapping Center, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Hum Brain Mapp 30:3783-94. 2009
    ..Although DTNBP1 relates to cortical thinning in schizophrenia, morphological changes in the disorder are influenced by additional genetic and/or environmental factors...
  21. pmc Construction of a 3D probabilistic atlas of human cortical structures
    David W Shattuck
    Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, 635 Charles Young Drive South, NRB1, Suite 225, Los Angeles, CA 90095, USA
    Neuroimage 39:1064-80. 2008
    ....
  22. pmc Neural components underlying behavioral flexibility in human reversal learning
    Dara G Ghahremani
    Department of Psychology, University of California, Los Angeles, Los Angeles, CA 90065, USA
    Cereb Cortex 20:1843-52. 2010
    ..These regions and lateral OFC represent distinct neural components that support behavioral flexibility important for adaptive learning...
  23. pmc Positive correlations between corpus callosum thickness and intelligence
    Eileen Luders
    Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, and Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
    Neuroimage 37:1457-64. 2007
    ..Our findings emphasize the importance of incorporating posterior (callosal) regions into the theories and models proposed to explain the anatomical substrates of intelligence...
  24. pmc Asymmetries of cortical thickness: effects of handedness, sex, and schizophrenia
    Liberty S Hamilton
    Laboratory of Neuroimaging, Geffen School of Medicine at UCLA, Los Angeles, California 90095 7334, USA
    Neuroreport 18:1427-31. 2007
    ..Thus, dextrality relates to cortical thickness asymmetries, although schizophrenia may differentially affect asymmetry patterns across handedness...
  25. ncbi request reprint Mapping cortical thickness and gray matter concentration in first episode schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1769, USA
    Cereb Cortex 15:708-19. 2005
    ..Cortical thickness and gray matter concentration mapping produce similar results, although the concentration metric may be influenced by diagnostic differences in extra-cortical cerebrospinal fluid and surface curvature/complexity...
  26. doi request reprint A collaborative knowledge base for cognitive phenomics
    F W Sabb
    Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA 90095 1759, USA
    Mol Psychiatry 13:350-60. 2008
    ..It is hoped that this new open resource can serve as a starting point that enables broadly collaborative knowledge-building, and help investigators select and prioritize endophenotypes for translational research...
  27. pmc Striatal dopamine d2/d3 receptor availability is reduced in methamphetamine dependence and is linked to impulsivity
    Buyean Lee
    Department of Psychiatry, Brain Research Institute, University of California, Los Angeles, Los Angeles, California 90024, USA
    J Neurosci 29:14734-40. 2009
    ..12 corrected). The findings suggest that low striatal D(2)/D(3) receptor availability may mediate impulsive temperament and thereby influence addiction...
  28. ncbi request reprint Regional specificity of cerebrospinal fluid abnormalities in first episode schizophrenia
    Katherine L Narr
    Laboratory of Neuroimaging, Division of Brain Mapping, UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095 1769, USA
    Psychiatry Res 146:21-33. 2006
    ..In contrast, sulcal and subarachnoid CSF increases may be manifest near or before the first episode but after brain development is complete, reflecting pronounced reductions in proximal brain tissue...
  29. ncbi request reprint Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial
    Richard S E Keefe
    Department of Psychiatry, John Umstead Hospital, Duke University Medical Center, Durham, NC 27710, USA
    Arch Gen Psychiatry 64:633-47. 2007
    ..The relative effect of the second-generation (atypical) antipsychotic drugs and older agents on neurocognition has not been comprehensively determined...
  30. pmc CSF sub-compartments in relation to plasma osmolality in healthy controls and in patients with first episode schizophrenia
    Handan Gunduz-Bruce
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Psychiatry Res 155:57-66. 2007
    ..These results suggest that plasma osmolality is related to ventricle size in healthy volunteers and that this physiological link is impaired in patients with first episode schizophrenia...
  31. pmc A unique adolescent response to reward prediction errors
    Jessica R Cohen
    Department of Psychology, University of California Los Angeles, Los Angeles, California, USA
    Nat Neurosci 13:669-71. 2010
    ..This suggests that heightened dopaminergic prediction error responsivity contributes to adolescent reward seeking...
  32. ncbi request reprint Functional magnetic resonance imaging of source versus item memory
    Jin Fan
    Department of Psychiatry, Weill Medical College of Cornell University, New York, NY 10021, USA
    Neuroreport 14:2275-81. 2003
    ..Hippocampal activation showed no difference between source and item retrieval. This pattern of results supports a model proposing a larger role for the frontal lobes in encoding and retrieval of source information...
  33. ncbi request reprint Cortisol levels in relation to hippocampal sub-regions in subjects with first episode schizophrenia
    Handan Gunduz-Bruce
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Schizophr Res 94:281-7. 2007
    ..Larger scale studies are needed to conclude a link between the two measures, yet it is possible that the negative association that was previously shown in other disorders may not apply to schizophrenia...
  34. ncbi request reprint White matter abnormalities in first-episode schizophrenia or schizoaffective disorder: a diffusion tensor imaging study
    Philip R Szeszko
    The Zucker Hillside Hospital, Department of Psychiatry Research, 75 59 263rd St, Glen Oaks, NY 11004, USA
    Am J Psychiatry 162:602-5. 2005
    ..The goal of this study was to investigate brain white matter abnormalities by using diffusion tensor imaging in patients with schizophrenia or schizoaffective disorder close to illness onset...
  35. pmc DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia
    Philip R Szeszko
    Feinstein Institute for Medical Research, Manhasset, NY, USA
    Biol Psychol 79:103-10. 2008
    ..Given that DISC1 plays a role in cerebral cortex development, polymorphisms in this gene may have relevance for neurobiological models of schizophrenia that have implicated cortical deficits in its pathophysiology...
  36. ncbi request reprint Adolescent immaturity in attention-related brain engagement to emotional facial expressions
    Christopher S Monk
    Section on Development and Affective Neuroscience and Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Neuroimage 20:420-8. 2003
    ..These findings suggest that adults show greater modulation of activity in relevant brain structures based on attentional demands, whereas adolescents exhibit greater modulation based on emotional content...
  37. ncbi request reprint Category fluency in first-episode schizophrenia
    Tania Giovannetti
    Moss Rehabilitation Research Institute, Philadelphia, Pennsylvania 19141, USA
    J Int Neuropsychol Soc 9:384-93. 2003
    ..e., semantic search/access, response monitoring) or global cognitive impairment...
  38. ncbi request reprint Predictors of medication discontinuation by patients with first-episode schizophrenia and schizoaffective disorder
    Delbert G Robinson
    Department of Psychiatry Research, Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Schizophr Res 57:209-19. 2002
    ..Although extensively studied in multi-episode patients, little data exist on medication adherence by first-episode patients...
  39. ncbi request reprint No evidence for phenotypic variation between probands in case-control versus family-based association studies of schizophrenia
    Anil K Malhotra
    Hillside Hospital, Psychiatry Research, Glen Oaks, New York 11004, USA
    Am J Med Genet 114:509-11. 2002
    ....
  40. ncbi request reprint Neurocognitive correlates of the COMT Val(158)Met polymorphism in chronic schizophrenia
    Robert M Bilder
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Biol Psychiatry 52:701-7. 2002
    ....
  41. ncbi request reprint Frontal white matter microstructure, aggression, and impulsivity in men with schizophrenia: a preliminary study
    Matthew J Hoptman
    Division of Clinical Research and the Center for Advanced Brain Imaging, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    Biol Psychiatry 52:9-14. 2002
    ..Aggression and impulsivity may involve altered frontal white matter...
  42. ncbi request reprint Neuropsychological correlates of hippocampal volumes in patients experiencing a first episode of schizophrenia
    Philip R Szeszko
    Department of Psychiatry Research, Hillside Hospital, a division of North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Am J Psychiatry 159:217-26. 2002
    ..This study investigated the neuropsychological correlates of hippocampal volume in 43 men and 32 women experiencing a first episode of schizophrenia...
  43. ncbi request reprint Smaller anterior hippocampal formation volume in antipsychotic-naive patients with first-episode schizophrenia
    Philip R Szeszko
    Department of Psychiatry Research, The Zucker Hillside Hospital, 75 59 263rd St, Glen Oaks, NY 11004, USA
    Am J Psychiatry 160:2190-7. 2003
    ..The authors investigated volumetric alterations of the anterior hippocampal formation in patients experiencing a first episode of schizophrenia relative to healthy comparison subjects...
  44. ncbi request reprint Clinical and neuropsychological correlates of white matter abnormalities in recent onset schizophrenia
    Philip R Szeszko
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Neuropsychopharmacology 33:976-84. 2008
    ..These abnormalities have clinical and neuropsychological correlates, which may be useful in further characterizing structure-function relations in schizophrenia and constraining neurobiological models of the disorder...
  45. ncbi request reprint Catechol O-methyltransferase Val158Met polymorphism in schizophrenia: differential effects of Val and Met alleles on cognitive stability and flexibility
    Karen A Nolan
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Am J Psychiatry 161:359-61. 2004
    ..They hypothesized that the Val and Met alleles would be associated with deficits in imitation learning and reversal learning, respectively...
  46. ncbi request reprint A developmental examination of gender differences in brain engagement during evaluation of threat
    Erin B McClure
    Section on Development and Affective Neuroscience, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Biol Psychiatry 55:1047-55. 2004
    ..Recent theoretical models suggest that developmental changes in brain functioning play important roles in the emergence of such gender differences...
  47. ncbi request reprint Olfactory functions and volumetric measures of orbitofrontal and limbic regions in schizophrenia
    Claudia I Rupp
    Department of Psychiatry, Medical University Innsbruck, Austria
    Schizophr Res 74:149-61. 2005
    ..In this study, we examined the relationship between different olfactory functions and volumes of the hippocampus-amygdala complex (HAC) and the orbitofrontal brain region using magnetic resonance imaging (MRI)...
  48. pmc Quantitative MRI measures of orbitofrontal cortex in patients with chronic schizophrenia or schizoaffective disorder
    Matthew J Hoptman
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Psychiatry Res 140:133-45. 2005
    ..Larger left OFC gray matter volumes and larger OFC white matter volumes bilaterally were associated with greater levels of aggression. These findings are discussed in the context of potential iatrogenic effects...
  49. ncbi request reprint Symptomatic and functional recovery from a first episode of schizophrenia or schizoaffective disorder
    Delbert G Robinson
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Am J Psychiatry 161:473-9. 2004
    ..e., sustained improvement in both symptoms and social/vocational functioning) when examined decades after an index admission. This study addressed recovery during the crucial early course of the illness...
  50. ncbi request reprint Neurocognitive profile in adolescents with early-onset schizophrenia: clinical correlates
    Joseph P Rhinewine
    Department of Psychiatry Research Zucker Hillside Hospital, Glen Oaks, New York 11004, USA
    Biol Psychiatry 58:705-12. 2005
    ..Information concerning the severity, pattern, and clinical correlates of these deficits in EOS remains limited...
  51. ncbi request reprint Neurocognitive effects of clozapine, olanzapine, risperidone, and haloperidol in patients with chronic schizophrenia or schizoaffective disorder
    Robert M Bilder
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Am J Psychiatry 159:1018-28. 2002
    ....
  52. ncbi request reprint Neurocognitive correlates of response to treatment in formal thought disorder in patients with first-episode schizophrenia
    Rita Z Goldstein
    Brookhaven National Laboratory, Upton, New York 11973, USA
    Neuropsychiatry Neuropsychol Behav Neurol 15:88-98. 2002
    ..To examine the independent contribution of executive versus semantic function to improvement in formal thought disorder after initial stabilization in a first-episode sample...
  53. ncbi request reprint White matter abnormalities in obsessive-compulsive disorder: a diffusion tensor imaging study
    Philip R Szeszko
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Arch Gen Psychiatry 62:782-90. 2005
    ....
  54. ncbi request reprint The effects of second-generation antipsychotics on cognitive functioning and psychosocial outcome in schizophrenia
    Elisabeth M Weiss
    Department of Biological Psychiatry, Innsbruck University Clinics, Anichstrasse 35, 6020 Innsbruck University Clinics, Anichtrasse 35, 6020 Innsbruck, Austria
    Psychopharmacology (Berl) 162:11-7. 2002
    ..In this context it also addresses several methodological and conceptional issues that limited the comparison of these studies...
  55. ncbi request reprint Genetic linkage for schizophrenia?
    Jan Volavka
    Am J Psychiatry 161:1134-5; author reply 1135-6. 2004
  56. ncbi request reprint Baseline neurocognitive deficits in the CATIE schizophrenia trial
    Richard S E Keefe
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
    Neuropsychopharmacology 31:2033-46. 2006
    ..Multiple analyses suggested that a broad cognitive deficit characterizes this sample. These deficits are modestly related to negative symptoms and essentially independent of positive symptom severity...
  57. ncbi request reprint Investigation of unirhinal olfactory identification in antipsychotic-free patients experiencing a first-episode schizophrenia
    Philip R Szeszko
    Department of Psychiatry Research, North Shore Long Island Jewish Health System, Zucker Hillside Hospital, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Schizophr Res 67:219-25. 2004
    ....
  58. ncbi request reprint Sex differences in frontal lobe white matter microstructure: a DTI study
    Philip R Szeszko
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Neuroreport 14:2469-73. 2003
    ..Our findings may be indicative of increased directional coherence and/or density of left hemisphere white matter fibers and a leftward asymmetry of this structural integrity among women compared to men...
  59. ncbi request reprint Anterior cingulate grey-matter deficits and cannabis use in first-episode schizophrenia
    Philip R Szeszko
    Zucker Hillside Hospital, Psychiatry Research, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Br J Psychiatry 190:230-6. 2007
    ..Despite the high prevalence of cannabis use in schizophrenia, few studies have examined the potential relationship between cannabis exposure and brain structural abnormalities in schizophrenia...
  60. ncbi request reprint Increased stress and smaller anterior hippocampal volume
    Philip R Szeszko
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Neuroreport 17:1825-8. 2006
    ..Our results may also have implications for neuropsychiatric disorders that have implicated stress and hippocampal abnormalities in their pathogenesis...
  61. ncbi request reprint Lack of normal association between cerebellar volume and neuropsychological functions in first-episode schizophrenia
    Philip R Szeszko
    Department of Psychiatry Research, Zucker Hillside Hospital, North Shore Long Island Jewish Health System, NY 11004, USA
    Am J Psychiatry 160:1884-7. 2003
    ..Few studies, however, have examined the relationship between cerebellar size and neuropsychological functioning in schizophrenia. The authors' goal was to examine this relationship in patients and healthy comparison subjects...
  62. ncbi request reprint Neurocognitive assessment in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project schizophrenia trial: development, methodology, and rationale
    Richard S E Keefe
    Neurocognitive Assessment Unit, Duke University Medical Center, Durham, NC 27710, USA
    Schizophr Bull 29:45-55. 2003
    ....
  63. pmc Aggression and quantitative MRI measures of caudate in patients with chronic schizophrenia or schizoaffective disorder
    Matthew J Hoptman
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    J Neuropsychiatry Clin Neurosci 18:509-15. 2006
    ..The relationship between aggression and caudate volumes may be related to the iatrogenic effects of long-term treatment with typical antipsychotic agents or to a direct effect of schizophrenic processes on the caudate...
  64. ncbi request reprint Reversed cerebellar asymmetry in men with first-episode schizophrenia
    Philip R Szeszko
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Biol Psychiatry 53:450-9. 2003
    ..In this study, we investigated whether patients experiencing first-episode schizophrenia differed from healthy comparison subjects in regional cerebellar volumes or cerebellar asymmetry...
  65. pmc Patterns of stress in schizophrenia
    Julia D Betensky
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Psychiatry Res 160:38-46. 2008
    ....
  66. ncbi request reprint Neurodevelopmental aspects of spatial navigation: a virtual reality fMRI study
    Daniel S Pine
    Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Building 10, Room 4N 222 MSC1381, Bethesda, Maryland 20892 1381, USA
    Neuroimage 15:396-406. 2002
    ..Consistent with developmental models, these findings relate maturation in the coding of spatial information to functional changes in a distributed, left-lateralized neural network...

Research Grants18

  1. COGNITIVE PHENOTYPING:NEUROPSYCHIATRIC THERAPEUTICS(RMI)
    Robert Bilder; Fiscal Year: 2006
    ....
  2. LONGITUDINAL NEUROIMAGING OF FIRST EPISODE SCHIZOPHRENIA
    Robert Bilder; Fiscal Year: 2003
    ....
  3. LONGITUDINAL EVALUATION OF PATIENTS W/ FIRST EPISODE SCHIZOPHRENIA
    Robert Bilder; Fiscal Year: 2002
    ..Specific Aim 5. Cross-validate and integrate the methods developed here with methods based on Surface Parameterization (Project 1) and other comparable or compatible approaches. ..