GUOQIANG BI

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi Temporal asymmetry in spike timing-dependent synaptic plasticity
    Guo Qiang Bi
    Department of Neurobiology, University of Pittsburgh School of Medicine, 200 Lothrop Street, E1451 BST, 15213, Pittsburgh, PA, USA
    Physiol Behav 77:551-5. 2002
  2. ncbi Coactivation and timing-dependent integration of synaptic potentiation and depression
    Huai-Xing Wang
    Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    Nat Neurosci 8:187-93. 2005
  3. ncbi Timing in synaptic plasticity: from detection to integration
    Guo Qiang Bi
    Department of Neurobiology and Center for the Neural Basis of Cognition, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Trends Neurosci 28:222-8. 2005
  4. ncbi Synaptic modification by correlated activity: Hebb's postulate revisited
    G Bi
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720 3200, USA
    Annu Rev Neurosci 24:139-66. 2001
  5. ncbi Recent advances in basic neurosciences and brain disease: from synapses to behavior
    Guo Qiang Bi
    Department of Neurobiology, University of Pittsburgh, Pittsburgh, USA
    Mol Pain 2:38. 2006
  6. ncbi Spatiotemporal specificity of synaptic plasticity: cellular rules and mechanisms
    Guo Qiang Bi
    Department of Neurobiology, University of Pittsburgh School of Medicine, 200 Lothrop St E 1452 BST, Pittsburgh, PA 15261, USA
    Biol Cybern 87:319-32. 2002
  7. ncbi Calcium time course as a signal for spike-timing-dependent plasticity
    Jonathan E Rubin
    Department of Mathematics, University of Pittsburgh, 301 Thackeray Hall, Pittsburgh, PA 15260, USA
    J Neurophysiol 93:2600-13. 2005
  8. ncbi Synaptic mechanisms of persistent reverberatory activity in neuronal networks
    Pak-Ming Lau
    Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Proc Natl Acad Sci U S A 102:10333-8. 2005
  9. ncbi Probing vesicle dynamics in single hippocampal synapses
    Matthew Shtrahman
    Department of Physics and Astronomy, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Biophys J 89:3615-27. 2005
  10. ncbi Modular competition driven by NMDA receptor subtypes in spike-timing-dependent plasticity
    Richard C Gerkin
    Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA
    J Neurophysiol 97:2851-62. 2007

Research Grants

  1. Spatio-Temporal Specificity of Synaptic Plasticity
    GUOQIANG BI; Fiscal Year: 2007

Detail Information

Publications12

  1. ncbi Temporal asymmetry in spike timing-dependent synaptic plasticity
    Guo Qiang Bi
    Department of Neurobiology, University of Pittsburgh School of Medicine, 200 Lothrop Street, E1451 BST, 15213, Pittsburgh, PA, USA
    Physiol Behav 77:551-5. 2002
    ..We also discuss our recent studies using a "triplet-spiking" paradigm that reveals nonlinear, temporally asymmetric integration of STDP...
  2. ncbi Coactivation and timing-dependent integration of synaptic potentiation and depression
    Huai-Xing Wang
    Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    Nat Neurosci 8:187-93. 2005
    ..The timing dependence of modular interaction provides a quantitative framework for understanding the temporal integration of STDP...
  3. ncbi Timing in synaptic plasticity: from detection to integration
    Guo Qiang Bi
    Department of Neurobiology and Center for the Neural Basis of Cognition, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Trends Neurosci 28:222-8. 2005
    ..This review is part of the TINS Synaptic Connectivity series...
  4. ncbi Synaptic modification by correlated activity: Hebb's postulate revisited
    G Bi
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720 3200, USA
    Annu Rev Neurosci 24:139-66. 2001
    ....
  5. ncbi Recent advances in basic neurosciences and brain disease: from synapses to behavior
    Guo Qiang Bi
    Department of Neurobiology, University of Pittsburgh, Pittsburgh, USA
    Mol Pain 2:38. 2006
    ..The second international meeting on Neurons and Brain Disease will be held in Toronto (August 29-31, 2007)...
  6. ncbi Spatiotemporal specificity of synaptic plasticity: cellular rules and mechanisms
    Guo Qiang Bi
    Department of Neurobiology, University of Pittsburgh School of Medicine, 200 Lothrop St E 1452 BST, Pittsburgh, PA 15261, USA
    Biol Cybern 87:319-32. 2002
    ..I also highlight several unresolved issues, and suggest future lines of research...
  7. ncbi Calcium time course as a signal for spike-timing-dependent plasticity
    Jonathan E Rubin
    Department of Mathematics, University of Pittsburgh, 301 Thackeray Hall, Pittsburgh, PA 15260, USA
    J Neurophysiol 93:2600-13. 2005
    ..This may account for the variability of STDP outcomes seen within hippocampal cultures, under repeated application of a single experimental protocol, as well as for that seen in multiple spike experiments across different systems...
  8. ncbi Synaptic mechanisms of persistent reverberatory activity in neuronal networks
    Pak-Ming Lau
    Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Proc Natl Acad Sci U S A 102:10333-8. 2005
    ..Thus, the oft-overlooked asynchronous phase of synaptic transmission plays a central role in the emergent phenomenon of network reverberation...
  9. ncbi Probing vesicle dynamics in single hippocampal synapses
    Matthew Shtrahman
    Department of Physics and Astronomy, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Biophys J 89:3615-27. 2005
    ..Our measurements suggest that the movement of vesicles to the active zone is the rate-limiting step in this process...
  10. ncbi Modular competition driven by NMDA receptor subtypes in spike-timing-dependent plasticity
    Richard C Gerkin
    Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA
    J Neurophysiol 97:2851-62. 2007
    ..Using a simple model, we show that such a modular competition recapitulates our observations...
  11. ncbi Calcium and synaptic dynamics underlying reverberatory activity in neuronal networks
    Vladislav Volman
    School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, Israel
    Phys Biol 4:91-103. 2007
    ..The simplicity of our model enabled a number of predictions that were confirmed by additional analyses of experimental manipulations...
  12. ncbi Synaptic modification in neural circuits: a timely action
    Benedikt Berninger
    Department of Neuroimmunology, Max Planck Institute of Neurobiology, D 82152 Martinsried, Germany
    Bioessays 24:212-22. 2002
    ..Ultimately, this synaptic property might also be fundamental for the cognitive process by which we structure our experience through cause and effect relations...

Research Grants5

  1. Spatio-Temporal Specificity of Synaptic Plasticity
    GUOQIANG BI; Fiscal Year: 2007
    ..Ultimately, these studies will provide insights into and may lead to cures for human diseases in the nervous system, especially those related to learning and memory. ..