E Bi

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Role of Inn1 and its interactions with Hof1 and Cyk3 in promoting cleavage furrow and septum formation in S. cerevisiae
    Ryuichi Nishihama
    Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Cell Biol 185:995-1012. 2009
  2. pmc Immobile myosin-II plays a scaffolding role during cytokinesis in budding yeast
    Carsten Wloka
    Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA
    J Cell Biol 200:271-86. 2013
  3. pmc The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization
    Xiang Dong Gao
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Room 1012, BRB II III, 421 Curie Boulevard, Philadelphia, PA 19104 6058, USA
    J Cell Biol 162:635-46. 2003
  4. pmc Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae
    Jianying Luo
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6058, USA
    J Cell Biol 165:843-55. 2004
  5. pmc Adjacent positioning of cellular structures enabled by a Cdc42 GTPase-activating protein-mediated zone of inhibition
    Zongtian Tong
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Cell Biol 179:1375-84. 2007
  6. pmc Biphasic targeting and cleavage furrow ingression directed by the tail of a myosin II
    Xiaodong Fang
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Cell Biol 191:1333-50. 2010
  7. pmc Daughter cell identity emerges from the interplay of Cdc42, septins, and exocytosis
    Satoshi Okada
    Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Dev Cell 26:148-61. 2013
  8. pmc Cell polarization and cytokinesis in budding yeast
    Erfei Bi
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6058, USA
    Genetics 191:347-87. 2012
  9. ncbi request reprint Cytokinesis in budding yeast: the relationship between actomyosin ring function and septum formation
    E Bi
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia 19104 6058, USA
    Cell Struct Funct 26:529-37. 2001
  10. ncbi request reprint Cdc42 interacts with the exocyst and regulates polarized secretion
    X Zhang
    Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Biol Chem 276:46745-50. 2001

Collaborators

  • Xiang Dong Gao
  • Daniel J Lew
  • John R Pringle
  • Masayuki Onishi
  • Hay Oak Park
  • X Zhang
  • P Novick
  • Elizabeth A Vallen
  • Carsten Wloka
  • Xiaodong Fang
  • Ryuichi Nishihama
  • Jianying Luo
  • Satoshi Okada
  • Julia Hanna
  • Christopher Dravis
  • Zongtian Tong
  • Natasha S Savage
  • Lydia Thé
  • Marcin Leda
  • Younghoon Oh
  • Andrew B Goryachev
  • Mirko Travaglia
  • Masayuki Iwase
  • Jennifer H Schreiter
  • Katarina Moravcevic
  • Mark A Lemmon
  • Margaret F Lippincott
  • Haesun Han
  • Indrani Bose
  • Audrey S Howell
  • Serguei E Tcheperegine
  • Becky Drees

Detail Information

Publications10

  1. pmc Role of Inn1 and its interactions with Hof1 and Cyk3 in promoting cleavage furrow and septum formation in S. cerevisiae
    Ryuichi Nishihama
    Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Cell Biol 185:995-1012. 2009
    ..Thus, Inn1 and Cyk3 appear to cooperate in activating Chs2 for PS formation, which allows coordination of AMR contraction with ingression of the cleavage furrow...
  2. pmc Immobile myosin-II plays a scaffolding role during cytokinesis in budding yeast
    Carsten Wloka
    Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA
    J Cell Biol 200:271-86. 2013
    ..displayed Myo1-dependent immobility during cytokinesis, suggesting that Myo1 plays a scaffolding role in the assembly of a cytokinesis machine...
  3. pmc The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization
    Xiang Dong Gao
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Room 1012, BRB II III, 421 Curie Boulevard, Philadelphia, PA 19104 6058, USA
    J Cell Biol 162:635-46. 2003
    ..Using a strain defective in polarized secretion and actin-patch organization, we showed that a change in actin-patch organization could be a consequence of the fusion of mistargeted vesicles with the plasma membrane...
  4. pmc Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae
    Jianying Luo
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6058, USA
    J Cell Biol 165:843-55. 2004
    ..We also identify Mlc2p as the regulatory light chain for Myo1p and demonstrate its role in Myo1p ring disassembly, a function likely conserved among eukaryotes...
  5. pmc Adjacent positioning of cellular structures enabled by a Cdc42 GTPase-activating protein-mediated zone of inhibition
    Zongtian Tong
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Cell Biol 179:1375-84. 2007
    ..Thus, Cdc42 activators and GAPs establish concentric zones of action such that polarization is directed to occur adjacent to but not within the previous cell division site...
  6. pmc Biphasic targeting and cleavage furrow ingression directed by the tail of a myosin II
    Xiaodong Fang
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Cell Biol 191:1333-50. 2010
    ..Our study establishes a biphasic targeting mechanism for myosin II and highlights an underappreciated role of the AMR in cytokinesis beyond force generation...
  7. pmc Daughter cell identity emerges from the interplay of Cdc42, septins, and exocytosis
    Satoshi Okada
    Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Dev Cell 26:148-61. 2013
    ..Our findings define a fundamental mechanism underlying eukaryotic cell fate differentiation. ..
  8. pmc Cell polarization and cytokinesis in budding yeast
    Erfei Bi
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6058, USA
    Genetics 191:347-87. 2012
    ..In this chapter, we discuss the mechanics and spatial control of polarity development and cytokinesis, emphasizing the key concepts, mechanisms, and emerging questions in the field...
  9. ncbi request reprint Cytokinesis in budding yeast: the relationship between actomyosin ring function and septum formation
    E Bi
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia 19104 6058, USA
    Cell Struct Funct 26:529-37. 2001
    ..Here we review and provide additional evidence that defines the functional and molecular relationship between actomyosin ring function and septum formation...
  10. ncbi request reprint Cdc42 interacts with the exocyst and regulates polarized secretion
    X Zhang
    Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Biol Chem 276:46745-50. 2001
    ..These results have revealed a role for Cdc42 in exocytosis. We propose that Cdc42 coordinates the vesicle docking machinery and the actin cytoskeleton for polarized secretion...

Research Grants14

  1. SIGNALING MECHANISMS IN CELL POLARITY IN YEAST
    Erfei Bi; Fiscal Year: 1999
    ..Thus, studying the signaling mechanisms of Cdc42p in yeast represents an important bridge between basic and clinical sciences. ..
  2. SIGNALING MECHANISMS IN CELL POLARITY IN YEAST
    Erfei Bi; Fiscal Year: 2011
    ..Deregulation of Cdc42p activity in mammals is associated with serious human diseases, such as cancer. Thus, studying the signaling mechanisms of Cdc42p in yeast will have profound implication in basic biology and clinical sciences. ..
  3. SIGNALING MECHANISMS IN CELL POLARITY IN YEAST
    Erfei Bi; Fiscal Year: 2000
    ..Thus, studying the signaling mechanisms of Cdc42p in yeast represents an important bridge between basic and clinical sciences. ..
  4. SIGNALING MECHANISMS IN CELL POLARITY IN YEAST
    Erfei Bi; Fiscal Year: 2001
    ..Thus, studying the signaling mechanisms of Cdc42p in yeast represents an important bridge between basic and clinical sciences. ..
  5. Mechanisms of Cytokinesis in Yeast
    Erfei Bi; Fiscal Year: 2010
    ..Failure in cytokinesis is associated with serious human diseases such as cancer. Thus, studying the mechanisms of cytokinesis will have profound implications in basic as well as clinical sciences. ..
  6. SIGNALING MECHANISMS IN CELL POLARITY IN YEAST
    Erfei Bi; Fiscal Year: 2009
    ..Deregulation of Cdc42p activity in mammals is associated with serious human diseases, such as cancer. Thus, studying the signaling mechanisms of Cdc42p in yeast will have profound implication in basic biology and clinical sciences. ..
  7. SIGNALING MECHANISMS IN CELL POLARITY IN YEAST
    Erfei Bi; Fiscal Year: 2010
    ..Deregulation of Cdc42p activity in mammals is associated with serious human diseases, such as cancer. Thus, studying the signaling mechanisms of Cdc42p in yeast will have profound implication in basic biology and clinical sciences. ..
  8. SIGNALING MECHANISMS IN CELL POLARITY IN YEAST
    Erfei Bi; Fiscal Year: 2009
    ..Deregulation of Cdc42p activity in mammals is associated with serious human diseases, such as cancer. Thus, studying the signaling mechanisms of Cdc42p in yeast will have profound implication in basic biology and clinical sciences. ..
  9. SIGNALING MECHANISMS IN CELL POLARITY IN YEAST
    Erfei Bi; Fiscal Year: 2007
    ..Thus, studying the signaling mechanisms of Cdc42p in yeast will have profound implications in basic biology and clinical sciences. ..
  10. SIGNALING MECHANISMS IN CELL POLARITY IN YEAST
    Erfei Bi; Fiscal Year: 2005
    ..Thus, studying the signaling mechanisms of Cdc42p in yeast will have profound implications in basic biology and clinical sciences. ..
  11. SIGNALING MECHANISMS IN CELL POLARITY IN YEAST
    Erfei Bi; Fiscal Year: 2004
    ..Thus, studying the signaling mechanisms of Cdc42p in yeast will have profound implications in basic biology and clinical sciences. ..
  12. SIGNALING MECHANISMS IN CELL POLARITY IN YEAST
    Erfei Bi; Fiscal Year: 2003
    ..Thus, studying the signaling mechanisms of Cdc42p in yeast represents an important bridge between basic and clinical sciences. ..
  13. SIGNALING MECHANISMS IN CELL POLARITY IN YEAST
    Erfei Bi; Fiscal Year: 2002
    ..Thus, studying the signaling mechanisms of Cdc42p in yeast represents an important bridge between basic and clinical sciences. ..
  14. SIGNALING MECHANISMS IN CELL POLARITY IN YEAST
    Erfei Bi; Fiscal Year: 2006
    ..Thus, studying the signaling mechanisms of Cdc42p in yeast will have profound implications in basic biology and clinical sciences. ..